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LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

PARIS CEDEX, FR

LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE Patent applications
Patent application numberTitlePublished
20120077775MACROCYCLIC COMPOUNDS USEFUL AS INHIBITORS OF KINASES AND HSP90 - Disclosed are macrocyclic compounds of formulae I-V, which are analogs of the pochonin resorcylic acid lactones, and processes for the preparation of the compounds. The compounds disclosed are useful as inhibitors of kinases and Heat Shock Protein 90 (HSP 90). Also disclosed are pharmaceutical compositions comprising an effective kinase-inhibiting amount or an effective HSP90-inhibiting amount of the compounds and methods for the treatment of disorders that are mediated by kinases and HSP90.03-29-2012
20110283416METHODS FOR PLANT FIBER CHARACTERIZATION AND IDENTIFICATION - The present invention relates to materials and methods for the expression of a gene of interest preferably in seeds of plants, even more specifically in oilseed plants. In particular, the invention provides an expression cassette for regulating seed-preferential expression in plants.11-17-2011
20110212365Carbon-Coated Li-Containing Powders and Process for Production Thereof - The invention provides a new route for the synthesis of carbon-coated powders having the olivine or NASICON structure, which form promising classes of active products for the manufacture of rechargeable lithium batteries. Carbon-coating of the powder particles is necessary to achieve good performances because of the rather poor electronic conductivity of said structures. For the preparation of coated LiFePO09-01-2011
20110177534DIAGNOSTICS FOR MEMBRANOUS NEPHROPATHY - The invention relates to immunoassays, reagents, therapeutics and methods of diagnosing and prognosis evaluation of idiopathic membranous nephropathy (MN). Immunoassays comprise enzyme-linked immunoabsorbent assays and nephelometric immunoassays for serum auto-antibodies reactive against a phospholipase A2 receptor (PLA2R). Therapeutic methods include removal of the auto-antibodies by absorbance or administration of soluble PLA2R or fragments to sequester the auto-antibodies.07-21-2011
20100331343NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS - The present invention provides novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors according to formula (I) that are useful in the treatment or prophylaxis of physiological and/or pathophysiological conditions in mammals, preferably humans, that are mediated by GHS receptors. The present invention further provides GHS receptor antagonists and agonists that can be used for modulation of these receptors and are useful for treating above conditions, in particular growth retardation, cachexia, short-, medium- and/or long term regulation of energy balance; short-, medium- and/or long term regulation (stimulation and/or inhibition) of food intake; adipogenesis, adiposity and/or obesity; body weight gain and/or reduction; diabetes, diabetes type I, diabetes type II, tumor cell proliferation; inflammation, inflammatory effects, gastric postoperative ileus, postoperative ileus and/or gastrectomy (ghrelin replacement therapy).12-30-2010
201003300642-mercaptocyclopentanecarboxylic acid compounds, a process for their preparation and pharmaceutical compositions containing them - Compounds of formula (I):12-30-2010
20100324234COPOLYCONDENSATION POLYMERIZATION OF FLUOROPOLYMERS - Fluorinated copolymers are prepared via copolycondensation polymerization in a process comprising reacting A) a telechelic fluoroazido compound of formula N12-23-2010
20100324222CURABLE FLUOROELASTOMER COMPOSITIONS - This invention relates to curable fluoroelastomer compositions comprising a) fluoroelastomers having either nitrile, alkyne or azide cure sites and b) fluorinated curatives containing diazide, dinitrile or dialkyne groups for reacting with cure sites on the fluoroelastomer. Fluoroelastomers having azide cure sites form crosslinks with curatives having dinitrile or dialkyne groups. Fluoroelastomers having nitrile or alkyne cure sites form crosslinks with curatives having diazide groups.12-23-2010
20100222943FLIGHT CONTROL SYSTEM AND AIRCRAFT COMPRISING IT - The flight control system comprises: 09-02-2010
20100204853FLIGHT CONTROL SYSTEM AND AIRCRAFT COMPRISING IT - The flight control system comprises: 08-12-2010
20090268901CONTINUOUS VARIABLE QUANTUM ENCRYPTION KEY DISTRIBUTION SYSTEM - A continuous variable quantum encryption key distribution system comprises a sender (Alice) able to randomly choose the phase and the amplitude of each coherent light pulse of a signal, to provide a coherent state defined by a first quadrature and a second quadrature that are random, and to transmit to a receiver (Bob) the signal pulses (S) and a local oscillator (LO), the receiver comprising a homodyne detector (10-29-2009
20090111024Lithium transition-metal phosphate powder for rechargeable batteries - Methods of manufacture and use of phosphates of transition metals are described as positive electrodes for secondary lithium batteries, including a process for the production of LiMPO04-30-2009
20090072203Carbon-Coated Li-Containing Powders and Process for Production Thereof - The invention provides a new route for the synthesis of carbon-coated powders having the olivine or NASICON structure, which form promising classes of active products for the manufacture of rechargeable lithium batteries. Carbon-coating of the powder particles is necessary to achieve good performances because of the rather poor electronic conductivity of said structures. For the preparation of coated LiFePO03-19-2009

Patent applications by LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE