LAY LINE GENOMICS S.p.A.

Patent application number	Title	Published
LAY LINE GENOMICS S.p.A. Patent applications
20110206682	MONOCLONAL ANTIBODIES, SYNTHETIC AND BIOTECHNOLOGICAL DERIVATIVES THEREOF ACTING AS NGF-ANTAGONIST MOLECULES - Monoclonal antibodies, synthetic and biotechnological derivatives thereof (ScFv or others) are able to recognise the NGF high affinity receptor, TrkA, and act as NGF-antagonist molecules. Pharmacological compositions for therapy, gene therapy, diagnostics of neurological pathologies are also described. Transgenic animal models to study such pathologies are also described.	08-25-2011
20110145941	ANTIBODIES AND DERIVATIVES THEREOF - An anti-TrkA antibody is provided that comprises:	06-16-2011
20110105727	Method for the humanization of antibodies and humanized antibodies thereby obtained - Method for the humanization of the VII and VL variable regions of an animal antibody of known sequence, humanized animal antibody obtainable according to the method, in particular anti-NGF and anti-TrkA humanized animal antibodies.	05-05-2011
20090123464	Method for the potentiation of opioid analgesics effects on pain - According to the invention there is provided use of an anti-TrkA antibody capable of inhibiting the binding between NGF and TrkA combined with at least one opioid analgesic for the preparation of a medicament for treating and/or preventing pain.	05-14-2009

Patent applications by LAY LINE GENOMICS S.p.A.