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Laboratoire Tetra Medical

Annonay, FR

Laboratoire Tetra Medical Patent applications
Patent application numberTitlePublished
20120022242METHOD FOR PRODUCING AN ELONGATE POLYSACCHARIDE ELEMENT, IN PARTICULAR A CHITOSAN THREAD, AND POLYSACCCHARIDE THREAD OBTAINED - The invention relates to a method for producing an elongate polysaccharide element, in particular a chitosan thread, comprising an operation of extruding an extrusible solution of said polysaccharide through an extrusion die and an operation of coagulating the extruded solution. The extrusible solution is a hydroalcoholic solution containing an alcohol that does not form an azeotrope with water and which has a boiling point of more than 150° C. at atmospheric pressure. The coagulation operation includes a step of evaporating the water, preferably over the alcohol, producing a gelled extruded elongate element in the form of a mainly alcoholic gel, in particular by subjecting the extruded solution to a hot air flow. At least one operation of eliminating the alcohol contained in said gel makes it possible to obtain the elongate polysaccharide element. The chitosan thread has a crystalline structure corresponding to the anhydrous allomorph and a rupture stress of at least 150 MPa after being immersed in demineralised water for fifteen hours. The apparatus (01-26-2012