| KYOWA MEDEX CO., LTD. Patent applications |
| Patent application number | Title | Published |
| 20120003678 | NOVEL FRUCTOSYL PEPTIDE OXIDASE - A protein described in any one of [1] to [4] below is provided according to the present invention:
| 01-05-2012 |
| 20110243816 | FECES SAMPLING CONTAINER - It is to provide a device for sampling feces that enables an accurate and quantitative evaluation by decreasing the variations of feces sampling levels, wherein the confirmation of the presence or absence of feces sampling can be performed hygienically and simply from an outside of a container. A device for sampling feces comprising a feces sampling stick | 10-06-2011 |
| 20110223626 | METHOD FOR QUANTITATIVELY DETERMINING CHOLESTEROL IN LOW-DENSITY LIPOPROTEINS,REAGENT FOR QUANTITATIVE DETERMINATION,AND QUANTITATIVE DETERMINATION KIT - A method for measuring cholesterol in low-density lipoprotein contained in a sample, which comprises reacting a sample with (i) a combination of cholesterol ester hydrolase and cholesterol oxidase or (ii) a combination of cholesterol ester hydrolase, an oxidized coenzyme and cholesterol dehydrogenase in the presence of: [a] a polyoxyethylene-polyoxyalkylene alkylaryl ether; [b] one or more surfactants selected from the group consisting of a polyoxyethylene-polyoxyalkylene copolymer, a polyoxyethylene alkenyl ether, a polyoxyethylene branched alkyl ether, and a polyoxyethylene-polyoxyalkylene branched alkyl ether; [c] one or more surfactants selected from the group consisting of a primary amine, a secondary amine, a tertiary amine, and a quaternary ammonium; and [d] a polyanion, and measuring a substance formed or consumed in the reaction. | 09-15-2011 |
| 20110129816 | DEVICE FOR DETECTION OF INFLUENZA VIRUS - A device for detecting or quantifying influenza viruses in a sample, which comprises a detection region having a human anti-influenza virus nucleoprotein antibody immobilized onto a support, a sample supply region, and a sample-migrating region; and a kit for detecting or quantifying influenza viruses, which comprises a solid phase in which a human anti-influenza virus nucleoprotein antibody is fixed onto a carrier. | 06-02-2011 |
| 20100068738 | Method of Immunoassaying A Component to be Measured - A method of immunoassaying a component to be measured in a sample containing hemoglobin, which comprises reacting a component to be measured in a sample containing hemoglobin with an antibody capable of binding to the component in the presence of a bile acid derivative different from a bile acid derivative that is inherently contained in the sample; a method of suppressing an interference of hemoglobin in immunoassaying a component to be measured in a sample containing hemoglobin, which comprises reacting a component to be measured in a sample containing hemoglobin with an antibody capable of binding to the component in the presence of a bile acid derivative different from a bile acid derivative that is inherently contained in the sample; a reagent of immunoassay of a component to be measured in a sample containing hemoglobin, which comprises a bile acid derivative, are described. | 03-18-2010 |
| 20100041080 | METHOD FOR QUANTIFICATION OF CHOLESTEROL IN SMALL DENSE LOW-DENSITY LIPOPROTEIN - A method for determination of sdLDL-C, which comprises the steps of: (i) in a reaction solution containing a surfactant which preferentially inhibits the reaction of sdLDL-C with enzymes for cholesterol measurement such as cholesterol ester hydrolase, allowing the enzymes for cholesterol measurement to act on a sample to eliminate HDL-C, VLDL-C, CM-C and LgLDL-C in the sample; (ii) adding a reagent which causes the reaction of sdLDL-C remaining in the reaction solution after the above step (i) to form hydrogen peroxide or reduced coenzyme, and measuring the formed hydrogen peroxide or reduced coenzyme; and (iii) determining the sdLDL-C concentration in the sample from the measurement value in (ii) and a previously prepared calibration curve. | 02-18-2010 |
| 20090286330 | Immunoassay using insoluble carrier particles and reagent therefor - The present invention provides a reagent for an immunoassay comprising insoluble carrier particles which can give the values to be determined with high accuracy and reliability, and can be stored for a long time; an immunoassay using the reagent; and a method for keeping the reagent stable. The present invention provides an immunoassay which comprises carrying out an antigen-antibody reaction using insoluble carrier particles in an aqueous medium comprising a buffer having its buffer capacity in a neutral or alkaline region (except for a carbonate-based buffer) and a carbonic acid compound releasing a bicarbonate ion; a reagent for an immunoassay comprising a buffer having its buffer capacity in a neutral or alkaline region (except for a carbonate-based buffer), a carbonic acid compound releasing bicarbonate ion, and insoluble carrier particles; and a method for keeping the reagent for an immunoassay comprising insoluble carrier particles stable, which comprises allowing insoluble carrier particles to co-exist in an aqueous medium comprising a buffer having its buffer capacity in a neutral or alkaline region (except for a carbonate-based buffer) and a carbonic acid compound releasing a bicarbonate ion. | 11-19-2009 |
| 20090280514 | METHOD FOR MEASUREMENT OF CHOLESTEROL IN HIGH-DENSITY LIPOPROTEIN - The present invention provides a method, a reagent and a kit for the simple and accurate measurement of HDL cholesterol. The method for the measurement of cholesterol in high-density lipoprotein in a sample comprises reacting the sample with i) cholesterol esterase and cholesterol oxidase or ii) cholesterol esterase, oxidized coenzyme and cholesterol dehydrogenase in an aqueous medium comprising a specific nitrogen-containing surfactant having the structure of amine or ammonium salt and a polyanion, and measuring the formed hydrogen peroxide or reduced coenzyme. | 11-12-2009 |
| 20090170139 | METHOD, REAGENT AND KIT FOR MEASUREMENT OF CHOLESTEROL IN REMNANT-LIKE PARTICLES - The present invention provides a method for simple and accurate measurement of cholesterol in remnant-like lipoprotein (RLP) (RLP-C) in a sample, which comprises the steps of: (i) eliminating cholesterol in lipoproteins other than RLP by reacting the sample with cholesterol oxidase, or cholesterol dehydrogenase and oxidized coenzyme, in an aqueous medium comprising surfactant A; (ii) reacting the reaction solution from which cholesterol in lipoproteins other than RLP has been eliminated in the above step (i) with cholesterol esterase and cholesterol oxidase, or cholesterol esterase, cholesterol dehydrogenase and oxidized coenzyme, in the presence of surfactant B to form hydrogen peroxide or reduced coenzyme; and (iii) measuring the hydrogen peroxide or reduced coenzyme formed in the above step (ii). | 07-02-2009 |
| 20090035803 | METHOD FOR STABILIZATION OF PEPTIDES IN A BIOLOGICAL SAMPLE - The present invention provides a simple method for the stabilization of a peptide in a biological sample and a reagent for the stabilization, a simple method for the preservation of a biological sample comprising a peptide and a reagent for the preservation, and a method for the accurate measurement of a peptide in a biological sample and a reagent for the measurement. Addition of a saccharide to a biological sample enables the stabilization of a peptide in the biological sample, the preservation of the biological sample comprising a peptide in a stable condition and the accurate measurement of a peptide in the biological sample. As the present invention can stabilize a peptide in a biological sample collected in the clinical examination, the peptide as a marker in the biological sample can be measured accurately in the clinical examination. | 02-05-2009 |
| 20090023167 | METHOD, REAGENT AND KIT FOR DETERMINATION OF CHOLESTEROL IN REMNANT-LIKE PARTICLES (RLP) - The present invention provides a method, a reagent and a kit for simple and sensitive determination of cholesterol in remnant-like particles without separation of components of a sample. A method for quantitatively determining remnant-like particle cholesterol in a sample, which comprises: in an aqueous medium containing the sample and in the presence of a combination of specific surfactants and a phospholipid-hydrolyzing enzyme, allowing remnant-like particle cholesterol in the sample to react with cholesterol esterase and cholesterol oxidase or cholesterol dehydrogenase (in the presence of oxidized coenzyme); and determining the formed hydrogen peroxide or reduced coenzyme. | 01-22-2009 |