| KYOTO UNIVERSITY Patent applications |
| Patent application number | Title | Published |
|---|
| 20120136131 | POLYMERIZATION INITIATOR FOR LIVING RADICAL POLYMERIZATION - Provided is a method of living radical polymerization which does not necessitate complicated and intricate synthesis of a dormant species and which is highly efficient. A halogenated derivative compound is used as a dormant species for initiating living radical polymerization. The derivative compound is obtained by halogenating an alcohol compound having a non-conjugated structure or an amine compound having a non-conjugated structure with a halogenating agent capable of halogenating an alcohol or amine. A radical produced by elimination of halogen from the halogenated derivative compound is allowed to react with the unsaturated bond of the monomer. Thus, the monomer, which has a radical-reactive unsaturated bond, is polymerized by living radical polymerization. Preferably, the halogenating agent is a compound (NIS or the like) which also has a function as a catalyst. | 05-31-2012 |
| 20120129172 | METHOD FOR SELECTING CLONE OF INDUCED PLURIPOTENT STEM CELLS - To efficiently identify and select a clone from clones of induced pluripotent stem cells (iPS cell) having low tumor formation rate in vivo when allowed to differentiate and transplanted in a living body, iPS cells of the clones are induced to differentiate, undifferentiated cells among the cells after the induction of differentiation are detected, and a clone having the content of the undifferentiated cell below a control is selected. | 05-24-2012 |
| 20120124706 | SCANNING PROBE MICROSCOPE AND METHOD FOR DETECTING PROXIMITY OF PROBES THEREOF - A scanning probe microscope includes: a first and second probes for scanning a sample while maintaining the distance to the sample surface; crystal oscillators holding each of the first and second probes; and a modulation oscillator for providing the first probe with a vibration of a specific frequency which is different from the resonant frequency of each crystal oscillator. A control unit monitors the vibration of the specific frequency of the first and second probes, detects proximity of the first probe and the second probe to each other based on the change of the specific frequencies, and controls the drive of the first and second probes. | 05-17-2012 |
| 20120114219 | IMAGE PROCESSING APPARATUS, INCUBATION OBSERVING APPARATUS, AND IMAGE PROCESSING METHOD - An image processing apparatus includes an outline extracting processing unit inputting a phase contrast image of a cell colony acquired by an observing unit, and extracting an outline of the cell colony, an extracting unit extracting a feature quantity of an outline part of the cell colony based on brightness information at an outside and brightness information at an inside of the outline on the phase contrast image, and an automatic discriminating unit automatically discriminating whether or not the cell colony is an iPS cell colony based on a discriminant criterion determined in advance and the feature quantity extracted by the extracting unit. | 05-10-2012 |
| 20120112187 | METHOD FOR FORMING METAL OXIDE FILM, METAL OXIDE FILM AND APPARATUS FOR FORMING METAL OXIDE FILM - The present method of forming a metal oxide film can increase production efficiency while maintaining the low resistance of the metal oxide film. The present method of forming a metal oxide film includes first misting a solution containing a metallic element and ethylenediamine; meanwhile, heating a substrate; and then, supplying the misted solution onto a first main surface of the substrate. | 05-10-2012 |
| 20120101391 | BLOOD VESSEL WALL ANALYZING DEVICE AND BLOOD VESSEL WALL ANALYZING METHOD - The present invention relates to a blood vessel wall analyzing apparatus provided with a structure enabling accurate measurement of plaque components in a blood vessel wall in a state that reduces the burden on a patient. In the blood vessel wall analyzing apparatus ( | 04-26-2012 |
| 20120100516 | PORTABLE PRACTICE TOOL FOR HEART MASSAGING IN CARDIOPULMONARY RESUSCITATION - Provided is a training box that is a practice tool for learning heart massaging (sternal compression) through experience; is low-cost, small-sized, light weight, and easy to transport; retains durability under repeated use; and on which AED use procedures can also be drilled. The portable practice tool for heart massaging in cardiopulmonary resuscitation is characterized by being provided with a chest-mockup main unit ( | 04-26-2012 |
| 20120095227 | COMPOUND HAVING HETERO RING SKELETON, AND PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUND USING THE AFOREMENTIONED COMPOUND AS ASYMMETRIC CATALYST - The present invention provides a compound having a heterocyclic skeleton, which is represented by of the formula (I): | 04-19-2012 |
| 20120087863 | Peptide Derivative and Use of the Same - A new peptide derivative is provided. The peptide derivative is represented by the following general formula (I), | 04-12-2012 |
| 20120085918 | ION BEAM IRRADIATION DEVICE AND METHOD FOR SUPPRESSING ION BEAM DIVERGENCE - To improve an efficiency of utilizing electrons and efficiently suppress an ion beam spread by a space charge effect while eliminating a need for a special magnetic pole structure by effectively using a space in the vicinity of a magnet, there are provided an ion source, a collimating magnet and a plurality of electron sources, wherein the electron sources are arranged in a magnetic field gradient region formed on an ion beam upstream side or ion beam downstream side of the collimating magnet and arranged outside a region passed by the ion beam, and an irradiation direction of the electrons is directed to supply the electrons to the magnetic field gradient region. | 04-12-2012 |
| 20120078117 | BLOOD VESSEL INNER WALL ANALYZING DEVICE AND BLOOD VESSEL INNER WALL ANALYZING METHOD - The present invention relates to a blood vessel inner wall analyzing apparatus provided with a structure for more accurately analyzing components of substances adhered to the inner walls of blood vessels. A blood vessel inner wall analyzing apparatus ( | 03-29-2012 |
| 20120070896 | METHOD FOR PRODUCING INDUCED PLURIPOTENT STEM CELLS AND METHOD FOR CULTURING THE SAME - [Object] To provide a technology for production of safer iPS cells and to provide a more efficient technology for culturing iPS cells. | 03-22-2012 |
| 20120058393 | BATTERY AND ENERGY SYSTEM - A battery including a positive electrode, a negative electrode mainly composed of sodium, and an electrolyte provided between the positive electrode and the negative electrode, the electrolyte being molten salt containing anions expressed with chemical formula (I) below and cations of metal, | 03-08-2012 |
| 20120046771 | MUSIC AUDIO SIGNAL GENERATING SYSTEM - A system for timbral change, capable of changing timbres included in an existing music audio signal to arbitrary timbres. Replaced harmonic peak parameters are created by replacing a plurality of harmonic peaks included in harmonic peak parameters, which are stored in a separated audio signal analyzing and storing section | 02-23-2012 |
| 20120045107 | METHOD OF ANALYZING MOTION OF IMAGING TARGET BY MEANS OF TAGGED MR IMAGES, AND MRI DEVICE - A method for analyzing motion of an imaging target by means of tagged MR images includes performing, on the same motion of an imaging target, N | 02-23-2012 |
| 20120040196 | THERMAL EXPANSION SUPPRESSING MEMBER AND ANTI-THERMALLY-EXPANSIVE MEMBER - Provided are a thermal expansion suppressing member having negative thermal expansion properties and a metal-based anti-thermally-expansive member having small thermal expansion. More specifically, provided are a thermal expansion suppressing member, including at least an oxide represented by the following general formula (1), and an anti-thermally-expansive member, including a metal having a positive linear expansion coefficient at 20° C., and a solid body including at least an oxide represented by the following general formula (1), the metal and solid being joined to each other: (Bi | 02-16-2012 |
| 20120040083 | METHOD FOR FORMING METAL OXIDE FILM, METAL OXIDE FILM, AND APPARATUS FOR FORMING METAL OXIDE FILM - The present invention aims at providing a method for forming a metal oxide film which can further improve the production efficiency while maintaining low resistance of a metal oxide film formed thereby. In the method for forming a metal oxide film of the present invention, a solution ( | 02-16-2012 |
| 20120037842 | ANTI-THERMALLY-EXPANSIVE RESIN AND ANTI-THERMALLY-EXPANSIVE METAL - Provided are resin-based and metal-based anti-thermally-expansive members each having small thermal expansion. More specifically, provided are an anti-thermally-expansive resin and an anti-thermally-expansive metal, each including a resin or a metal having a positive linear expansion coefficient at 20° C. and a solid particle dispersed in the resin or metal, in which the solid particle includes at least an oxide represented by the following general formula (1): (Bi | 02-16-2012 |
| 20120027038 | TWO-DIMENSIONAL PHOTONIC CRYSTAL LASER - A two-dimensional photonic crystal laser according to the present invention includes a two-dimensional photonic crystal layer | 02-02-2012 |
| 20120003299 | NOVEL HSP90-TARGETED ANTI-CANCER CHIMERIC PEPTIDE - Disclosed is a substance which is not accumulated stably in cells, does not cause the dysfunction of normal cells, and so on, and therefore can be used as an anti-cancer agent or in a DDS without having any adverse side effects. It is found that Hsp90 alone cannot exhibit its function as a chaperone in assisting the refolding of a protein such as survivin, but can exhibit this function when Hop (which is one of the partner proteins of Hsp90) binds to Hsp90. Thus, specifically disclosed herein is a chimeric peptide comprising of an Hsp90 TPR domain binding peptide and a cell-penetrating peptide. | 01-05-2012 |
| 20120002783 | NONDESTRUCTIVE INSPECTION SYSTEM USING NUCLEAR RESONANCE FLUORESCENCE - Isotope identification imaging of nuclear fuel material or explosives concealed in a drum or container in which nuclear reactor fuel or radioactive waste are sealed is realized while ensuring high precision, high reliability, and safety. A sample | 01-05-2012 |
| 20120002692 | Surface-emitting laser light source using two-dimensional photonic crystal - The present invention intends to provide a surface-emitting laser light source using a two-dimensional photonic crystal in which the efficiency of extracting light in a direction perpendicular to the surface is high. In a laser light source provided with a two-dimensional photonic crystal layer created from a plate-shaped matrix body in which a large number of holes are periodically arranged and an active layer arranged on one side of the two-dimensional photonic crystal layer, the holes are created to be columnar with a predetermined cross-sectional shape such as a circular shape, and the main axis of each of the columnar holes is tilted to a surface of the matrix body. When provided with this two-dimensional photonic crystal layer, the surface-emitting laser source using a two-dimensional photonic crystal has a Q | 01-05-2012 |
| 20110294850 | INDOLINE DERIVATIVES - The present invention provides a novel indoline derivative or a pharmacologically acceptable salt thereof or a solvate of the derivative or a salt thereof represented by the following formula (1) that has an excellent butyrylcholinesterase inhibitory activity. In the formula, R | 12-01-2011 |
| 20110288667 | INDUSTRIAL ROBOT SYSTEM - Provided is an industrial robot system which enables a reduction in an installation/adjustment period, and an increase in a no-error continuous operation period, and includes an action planning section ( | 11-24-2011 |
| 20110287112 | PROSTATE CANCER PROGRESSION INHIBITOR AND PROGRESSION INHIBITION METHOD - A prostate cancer progression inhibitor comprises 4-(4-cyano-2-{[2-(4-fluoro-1-naphthyl)propanoyl]amino}phenyl)butyric acid, a salt thereof, a solvate thereof, or a prodrug thereof. 4-(4-Cyano-2-{[2-(4-fluoro-1-naphthyl)propanoyl]amino}phenyl)butyric acid is useful as a prostate cancer progression inhibitor because this butyric acid has, for example, a growth inhibiting effect and a hormone responsiveness recovering effect on prostate cancer that has acquired hormone resistance. | 11-24-2011 |
| 20110286911 | HYDROGEN FLUORIDE PURIFICATION METHOD - To provide a novel method for purifying hydrogen fluoride, capable of efficiently reducing the content of arsenic in hydrogen fluoride. | 11-24-2011 |
| 20110275775 | CATALYST FOR LIVING RADICAL POLYMERIZATION - Provided is a catalyst used for a living radical polymerization method, which contains a central element consisting of carbon and at least one halogen atom binding to the central element. Further, a hydrocarbon compound can be used as a catalyst precursor. A monomer having a radical-reactive unsaturated bond is subjected to a radical polymerization reaction in the presence of the catalyst, consequently a polymer having narrow molecular weight distribution can be obtained, and thus the cost of the living radical polymerization can be remarkably reduced. The present invention is significantly more environmentally friendly and economically excellent than conventional living radical polymerization methods, due to advantages such as low toxicity of the catalyst, low amount of the catalyst used, high solubility of the catalyst, mild reaction conditions, and no coloration/no odor (no need of any post-treatments for a molded article), and the like. | 11-10-2011 |
| 20110270088 | ULTRASONOGRAPHIC DIAGNOSTIC SYSTEM AND ULTRASONIC DIAGNOSTIC DEVICE - An ultrasonic probe is constituted by ultrasonic transducer elements arranged in a direction. A beam forming unit forms acoustic field sensitivity modulated in a direction substantially orthogonal to scan lines in a subject by focusing an ultrasonic wave on a sequence of sampling points existing along the scan lines, and applying delay and apodization on a transmission/reception signal of each of the ultrasonic transducer elements. A detecting unit detects displacements at each sampling point in a direction tangential to the scan lines and in a direction tangential to curves substantially orthogonal to the scan lines by arithmetic between reception signals for the sampling point at different time points. Each curve of the curves substantially orthogonal to the scan lines is constituted by a sequence of points for which a total of times taken for ultrasonic pulses to reach from two points fixed to the ultrasonic probe is substantially the same. | 11-03-2011 |
| 20110265877 | ORGANIC THIN-FILM PHOTOELECTRIC CONVERSION ELEMENT AND METHOD OF MANUFACTURING THE SAME - The objectives of the present invention are to enable the manufacturing of an organic thin-film photoelectric conversion element under normal atmosphere, improve the photoelectric conversion efficiency of the element, and enhance its durability. A hole-blocking TiO2 layer is created between the photoelectric conversion layer and the electrode by a wet process. In the manufacturing process, the hole-blocking TiO2 layer is air-dried so that it will be an amorphous layer. It is possible to provide a concentration gradient layer of PCBM/P3HT in which the PCBM concentration is higher in a region close to the hole-blocking TiO2 layer. This structure will reduce the electric resistance of that region and minimize the current loss within the photoelectric conversion element. In the vicinity of the hole-blocking TiO2 layer, the PCBM concentration is increased, which in turn makes it easier for electrons to flow into the TiO2 layer since PCBM is electrically conductive. Due to these features, the organic thin-film photoelectric conversion element having the gradient structure of the present embodiment has a high level of photoelectric conversion efficiency and good durability. | 11-03-2011 |
| 20110263843 | MICROWAVE RADIATING DEVICE, CONNECTING TYPE MICROWAVE RADIATING DEVICE, AND METHODS OF PRODUCING SUGAR INGREDIENT FROM PLANT MATERIALS - The present invention provides a microwave radiating device which treats a radiated material by microwave irradiation; and further provides a method of producing a sugar ingredient from a plant material. | 10-27-2011 |
| 20110263756 | MOLDING MATERIAL CONTAINING UNSATURATED POLYESTER RESIN AND MICROFIBRILLATED PLANT FIBER - The present invention relates to a molding material comprising an unsaturated polyester resin and microfibrillated plant fibers, the microfibrillated plant fibers comprising cellulose and hemicellulose, and having a specific surface area of 5 to 20 m | 10-27-2011 |
| 20110251393 | HELICENE DERIVATIVE, AXIALLY ASYMMETRIC AMINO ACID, AMINE OR AMINOALCOHOL DERIVATIVE, PERYLENE DERIVATIVE OR SALT THEREOF, AND METHODS FOR PRODUCING SAME - The invention provides a helicene derivative, axially chiral amino acid, amine or amino alcohol derivative, and azaperylene, such as compounds represented by Formulae (I), (I′), (II), (II′), and (III): | 10-13-2011 |
| 20110250692 | METHOD FOR PRODUCING INDUCED PLURIPOTENT STEM CELLS - The present invention relates to a method for producing mammalian induced pluripotent stem cells, comprising introducing mammal-derived reprogramming factors comprising Oct3/4 and Nanog, or nucleic acids encoding Oct3/4 and Nanog, into mammal-derived somatic cells and thereby inducing induced pluripotent stem cells from the somatic cells, wherein the reprogramming factors comprise neither Sox2 nor nucleic acid encoding Sox2. | 10-13-2011 |
| 20110247107 | METHOD FOR PROCESSING OUTPUT OF SCANNING TYPE PROBE MICROSCOPE, AND SCANNING TYPE PROBE MICROSCOPE - Incident light | 10-06-2011 |
| 20110226622 | NOVEL CLEAR NATIVE ELECTROPHORESIS METHOD UTILIZING AROMATIC SULFONIC ACID COMPOUND - This invention provides a reagent for protein electrophoresis, an electrophoresis gel or buffer composition containing the reagent, and a protein separation method and an electrophoresis kit using the reagent and the composition. | 09-22-2011 |
| 20110223669 | METHOD OF EFFICIENTLY ESTABLISHING INDUCED PLURIPOTENT STEM CELLS - The present invention provides a method of improving the efficiency of establishment of induced pluripotent stem (iPS) cells, comprising inhibiting the p53 function in the step of somatic cell nuclear reprogramming. The inhibition of p53 function is achieved by bringing a substance selected from the group consisting of (1) chemical inhibitors of p53, (2) dominant negative mutants of p53 and nucleic acids that encode the same, (3) siRNAs and shRNAs against p53 and DNAs that encode the same, and (4) p53 pathway inhibitors, into contact with a somatic cell, and the like. The present invention also provides an agent for improving the efficiency of establishment of iPS cells, the agent comprising an inhibitor of p53 function, particularly (1) chemical inhibitors of p53, (2) dominant negative mutants of p53 and nucleic acids that encode the same, (3) siRNAs and shRNAs against p53 and DNAs that encode the same, and (4) p53 pathway inhibitors. The present invention further provides a method of producing an iPS cell, comprising bringing a nuclear reprogramming substance and an inhibitor of p53 function into contact with a somatic cell. | 09-15-2011 |
| 20110223529 | AQUEOUS PIGMENT DISPERSION AND APPLICATIONS THEREOF - Disclosed are an aqueous pigment dispersion containing at least a pigment, water, a high-molecular dispersant, and an alkali. The high-molecular dispersant is a diblock polymer having a formula (1) of A-B or a triblock polymer having a formula (2) of A-B-C. The diblock or triblock polymer is a diblock or triblock polymer obtained by polymerizing addition-polymerizable monomers with a radical generator while using an organic iodide as a polymerization initiating compound and an organic phosphorus compound, organic nitrogen compound or organic oxygen compound as a catalyst. Also disclosed are a production method and use of the aqueous pigment dispersion. With the high-molecular dispersant obtained by a simple living radical polymerization process free of the problems of conventional living radical polymerization and having a precisely-controlled molecular structure, the aqueous pigment dispersion can be obtained with the pigment dispersed in it. | 09-15-2011 |
| 20110206605 | Molecular Probe for Imaging of Pancreatic Islets and Use of the Same - A molecular probe for use in imaging of pancreatic islets is provided. The molecular probe comprises a polypeptide represented by the following formula (1), (2), or (3), or a polypeptide having homology with the foregoing polypeptide, | 08-25-2011 |
| 20110201520 | COMPOSITION AND METHOD FOR DIAGNOSING ESOPHAGEAL CANCER AND METASTASIS OF ESOPHAGEAL CANCER - This invention relates to a composition, kit, or DNA chip comprising polynucleotides and antibodies as probes for detecting, determining, or predicting the presence or metastasis of esophageal cancer, and to a method for detecting, determining, or predicting the presence or metastasis of esophageal cancer using the same. | 08-18-2011 |
| 20110201110 | EFFICIENT METHOD FOR ESTABLISHING INDUCED PLURIPOTENT STEM CELLS - The present invention provides a method of producing induced pluripotent stem (iPS) cells, comprising bringing a nuclear reprogramming substance into contact with dental pulp stem cells. By using dental pulp stem cells as a source of somatic cells, the efficiency of establishment of human iPS cells by transfer of 3 or 4 factors can be improved dramatically. Additionally, dental pulp stem cells are easily available because they can be isolated and prepared from extracted wisdom teeth and teeth extracted because of periodontal disease and the like, so that they can be used widely as a source of somatic cells for iPS cell banks. | 08-18-2011 |
| 20110194668 | X-RAY CT APPARATUS AND METHOD THEREOF - In an X-ray CT apparatus | 08-11-2011 |
| 20110187371 | Transmit-Receive Switching Circuit for NMR Spectrometer and NMR Spectrometer Incorporating Same - A transmit-receive switching circuit is offered which is for use in an NMR spectrometer that employs a solid-state NMR probe using a cooled detection coil. The switching circuit is cryogenically cooled to reduce thermal noise in use. The switching circuit has a first terminal for applying high-power RF pulses sent in from the power amplifier of the NMR spectrometer, a second terminal for sending the RF pulses applied from the first terminal to the NMR detector via crossed-diodes and for receiving and entering a low-power NMR signal detected by the NMR detector, and a third terminal for sending the NMR signal entered from the second terminal toward a preamplifier. Plural stages of shunts are connected to the transmission line connecting the second and third terminals such that one stage of shunt corresponds to a 90° phase shift in the RF radiation. | 08-04-2011 |
| 20110172948 | METHOD AND DEVICE FOR DETERMINING INTERFACE PARTICLE USED IN PARTICLE METHOD, AND PROGRAM FOR DETERMINING INTERFACE PARTICLE - A method for determination of interface particles used in a particle method is proposed. According to the present invention, the method for determination includes a density acquiring step of acquiring density in a predetermined range based on a determining-target particle, a first discriminating step of comparing the density with a predetermined threshold, a second discriminating step of determining a symmetry of an arrangement of the other particles within a predetermined range based on the determining-target particle, and a determining step of determining the determining-target particle as an interface particle in the case that the density determined by the first discriminating step is found to be smaller than the predetermined threshold and the arrangement of the other particles determined by the second discriminating step is found to be asymmetrical. | 07-14-2011 |
| 20110171129 | Molecular Probe Precursor for Imaging of Pancreatic Islet, and Use Thereof - A precursor of a molecular probe for imaging of pancreatic islets is provided. The precursor includes a polypeptide represented by any one of the following formulae (1) to (12), or a polypeptide having a homology with the foregoing polypeptide: | 07-14-2011 |
| 20110152523 | CATALYST FOR CROSS-COUPLING REACTION, AND PROCESS FOR PRODUCTION OF AROMATIC COMPOUND USING THE SAME - The present invention provides a process for efficiently producing an alkylated aromatic compound in good yield, by a cross-coupling reaction between an alkyl halide and an aromatic magnesium reagent. A process for producing an aromatic compound represented by Formula (1): | 06-23-2011 |
| 20110147896 | CLUSTER JET PROCESSING METHOD, SEMICONDUCTOR ELEMENT, MICROELECTROMECHANICAL ELEMENT, AND OPTICAL COMPONENT - A method for processing a sample using an electrically neutral reactive cluster is provided. The surface of a sample is processed by jetting out a mixed gas that is composed of a reactive gas and a gas with a boiling point lower than that of the reactive gas from a gas jetting part of a vacuum process room in which the sample is placed by a pressure in a range in which the mixed gas is not liquefied, in a predetermined direction, while adiabatically-expanding the mixed gas, thereby generating a reactive cluster and jetting the reactive cluster against the sample in the vacuum process room. | 06-23-2011 |
| 20110136965 | PIGMENT DISPERSIONS, BLOCK POLYMERS AND MANUFACTURING METHOD THEREFOR - Disclosed is a pigment dispersion containing at least a pigment, a liquid medium and a high-molecular dispersant. The high-molecular dispersant is a block polymer represented by A-B or A-B-C, in which A, B and C each represent a polymer block and the A and C blocks may be the same or different. The block polymer and its production process are also disclosed. The high-molecular dispersant is free of problems of a smell, coloration, a heavy metal and cost, and its use can provide a pigment dispersion excellent in the dispersion stability of a pigment. | 06-09-2011 |
| 20110135130 | METHOD FOR DESIGNING AUDIO SIGNAL PROCESSING SYSTEM FOR HEARING AID, AUDIO SIGNAL PROCESSING SYSTEM FOR HEARING AID, AND HEARING AID - A hearing aid tailored to a hard-of-hearing person is designed using sampled-data control theory. The method is for designing an audio signal processing system for a hearing aid, wherein the system comprises an AD converter for converting an analog audio input signal (y | 06-09-2011 |
| 20110133733 | MAGNETIC FIELD SENSOR DEVICE - A magnetic field sensor device | 06-09-2011 |
| 20110124832 | NOVEL LIVING RADICAL POLYMERIZATION METHOD USING ALCOHOL AS CATALYST - Provided is a low-cost, environmentally friendly living radical polymerization catalyst having high activity. The catalyst is used for a living radical polymerization method, and contains a central element consisting of oxygen and at least one halogen atom bound to the central element. Furthermore, an alcohol compound can be used as a catalyst precursor. By polymerizing a monomer in the presence of the catalyst, a polymer having narrow molecular weight distribution can be obtained, and the cost of the living radical polymerization can be remarkably reduced. The present invention is significantly more environmentally friendly and economically excellent than conventional living radical polymerization methods, due to advantages of the catalyst such as low toxicity of the catalyst, low amount of the catalyst necessary, high solubility of the catalyst, mild reaction conditions, and no coloration/no odor (which do not require a post-treatment for a molded article), and the like. | 05-26-2011 |
| 20110117645 | METHOD FOR PROLIFERATION OF PLURIPOTENT STEM CELLS - For efficient proliferation of pluripotent stem cells in a system free from any animal-derived material such as feeder cells or serum, the present invention provides a method for proliferation of pluripotent stem cells, which comprises culturing the pluripotent stem cells in a medium free from both feeder cells and serum in a system containing laminin-5. | 05-19-2011 |
| 20110117319 | NANOFIBER SHEET AND METHOD FOR MANUFACTURING THE SAME - A nanofiber sheet that has a high degree of transparency, a high modulus of elasticity, a low coefficient of linear thermal expansion as well as high degrees of flatness and smoothness, in particular, a nanofiber sheet produced as a uniform and flat sheet having a high optical transmittance with cellulose as the only component. This sheet has the following characteristics: Calculated for a thickness of 60 μm, the transmittance for parallel rays of light having a wavelength of 600 nm is equal to or higher than 70%; The Young's modulus measured in accordance with the JIS K7161 method is equal to or greater than 10 GPa; The coefficient of linear thermal expansion measured in accordance with the ASTM D606 method is equal to or smaller than 10 ppm/K. | 05-19-2011 |
| 20110112807 | Apparatus and method for evaluating deterioration performance - When a manager uses an input device to input the inspected states of the degrees of soundness of a plurality of objects, a data receiving unit receives them as inspection data. A deterioration characteristic calculating unit calculates the average value of the deterioration characteristics of the objects based on data related to the degrees of soundness of the plurality of objects that is received by the data receiving unit. A heterogeneous parameter calculating unit calculates a heterogeneous parameter for each heterogeneous factor that cannot be observed or is difficult to observe, and causes a variation in the deterioration characteristics. A benchmarking unit evaluates the influence of the heterogeneous factors on the deterioration characteristics based on the heterogeneous parameters, and an output unit outputs the evaluation result. | 05-12-2011 |
| 20110112242 | METHOD FOR PRODUCING DYE POLYMER, DYE POLYMER AND USE OF THE SAME - Disclosed are a production process of a dye polymer having a dye content of from 1 to 50 wt %, and the dye polymer and its use. The production process includes subjecting an addition-polymerizable monomer to living radical polymerization by using, as a polymerization initiator, a dye having a polymerization initiating group enabling the living radical polymerization. The dye polymer and a composition of the dye polymer and a pigment are useful as good coloring agents for various products or articles. The colored products or articles are high in transparency, and are provided with high added value. The dye polymer can also be used as a dispersant for pigments, thereby making it possible to afford pigment dispersions excellent in dispersion properties and dispersion stability. | 05-12-2011 |
| 20110098568 | IMAGE FORMING METHOD USING ULTRASOUND AND ABERRATION CORRECTION METHOD - An ultrasound image forming method comprises a first step of receiving a first signal reflected from the object, a second step of obtaining an aberration correction value based on the first signal thus received, a third step of receiving a second signal reflected from the object when a second ultrasound corrected based on the aberration correction value is transmitted to the object, and a fourth step of forming an image from the aberration correction value and the second signal. The center frequency of the second ultrasound is between 0.5 MHz and 20 MHz, the center frequency of the first ultrasound is between 3/16 and 9/20 of the center frequency of the second ultrasound. By this method, an accurate aberration correction value can be obtained and an ultrasound imaging with high resolution can be achieved even if aberrations are large and difficult to correct. | 04-28-2011 |
| 20110091974 | Conductive Substrate and Method for Introducing Nucleic Acid - A conductive substrate for introducing a nucleic acid into a cell, which comprises a carbon nanotube with a carboxyl group, and a nucleic acid, the carbon nanotube and the nucleic acid being loaded on an electrode substrate with a cationic surface. | 04-21-2011 |
| 20110083511 | SIGNAL PROCESSING APPARATUS, ULTRASONIC APPARATUS, CONTROL METHOD FOR SIGNAL PROCESSING APPARATUS, AND CONTROL METHOD FOR ULTRASONIC APPARATUS - A signal processing apparatus scans a beam of elastic waves into an object to be examined, acquires received waveform data of a plurality of scan lines, and performs signal processing to form a tomographic image of said object to be examined from the received waveform data of the plurality of scan lines. The signal processing apparatus includes a scan line correlation calculation part ( | 04-14-2011 |
| 20110082295 | NOVEL CURCUMIN DERIVATIVE - To develop a highly safe measure to treat Alzheimer's disease using a secretase-inhibiting substance, there is provided a compound represented by the following general formula (I) or a salt thereof: | 04-07-2011 |
| 20110081663 | Molecular Probe for Imaging of Pancreatic Islets and Use of the Same - A molecular probe for imaging of pancreatic islets is provided. The molecular probe includes a polypeptide represented by the following formula (1), or a polypeptide that has a homology with the foregoing polypeptide. | 04-07-2011 |
| 20110079883 | FERROELECTRIC THIN FILM - Provided is a ferroelectric thin film formed on a substrate and having an amount of remanent polarization increased in its entirety. The ferroelectric thin film contains a perovskite-type metal oxide formed on a substrate, the ferroelectric thin film containing a column group formed of multiple columns each formed of a spinel-type metal oxide, in which the column group is in a state of standing in a direction perpendicular to a surface of the substrate, or in a state of slanting at a slant angle in a range of −10° or more to +10° or less with respect to the perpendicular direction. | 04-07-2011 |
| 20110069541 | FERROMAGNETIC THIN WIRE ELEMENT - The present invention uses a ferromagnetic thin wire having a domain wall inside, with the magnetic moment at the center thereof being perpendicular to the longitudinal axis of the thin wire. With the domain wall being fixed by a domain wall fixation device (e.g. antiferromagnetic thin wires) so that the domain wall is prevented from moving in the ferromagnetic thin wire, when a direct current is supplied, the magnetic moment rotates in the immobilized domain wall. This rotation of the moment can be detected by a TMR element or the like. This configuration of the ferromagnetic thin wire element can be directly used to create a microwave oscillator or magnetic memory. | 03-24-2011 |
| 20110059483 | Molecular Probe for Imaging of Pancreatic Islets and Use of the Same - To provide a molecular probe for imaging of pancreatic islets. A molecular probe for use in imaging of pancreatic islets is provided. The molecular probe includes any one of the following polypeptides; polypeptides represented by the following formulae (1), (5), and (9); and polypeptides having homology with the foregoing polypeptides; | 03-10-2011 |
| 20110044170 | MULTI-HOP WIRELESS TERMINAL AND TRAFFIC CONTROL METHOD THEREOF - A multi-hop wireless terminal having a user application section, a traffic control section and a wireless transmitting/receiving section, the traffic control section enqueuing a packet of a transmission flow from the user application section and a packet of a forward flow from the wireless transmitting/receiving section in queues different for each flow and performing traffic control, where the traffic control section includes a queue manager for sorting a packet of each input flow into a corresponding queue and enqueuing the packet, and a packet scheduler for dequeuing a packet from each queue and outputting the packet, and where the packet scheduler selects from the queues a queue from which a packet is to be dequeued and output, based on transmission information of each of the flows. | 02-24-2011 |
| 20110039786 | METASTIN DERIVATIVE AND USE THEREOF - The present invention provides a metastin derivative represented by the formula (I): | 02-17-2011 |
| 20110039338 | METHOD OF EFFICIENTLY ESTABLISHING INDUCED PLURIPOTENT STEM CELLS - Provided is a method of improving the efficiency of establishment of induced pluripotent stem cells, comprising culturing somatic cells under hypoxic conditions in the step of nuclear reprogramming thereof. | 02-17-2011 |
| 20110033936 | CANINE iPS CELLS AND METHOD OF PRODUCING SAME - Provided are a method of producing canine iPS cells, comprising (a) the step of bringing into contact with each other a canine somatic cell and a nuclear reprogramming factor, and (b) the step of culturing the cell in a medium containing at least one substance selected from the group consisting of a mitogen-activated protein kinase kinase inhibitor, an activin receptor-like kinase inhibitor, a glycogen synthase kinase inhibitor, a L-type calcium channel agonist and a DNA methylation inhibitor, and a leukemia inhibitory factor, and canine iPS cells that can be obtained by the method. | 02-10-2011 |
| 20110033381 | MOLECULAR PROBE FOR IMAGING OF PANCREATIC ISLET AND THE PRECURSOR, AND USE OF THE SAME - A precursor of molecular probe for imaging of pancreatic islets is provided. A polypeptide represented by any one of the following formulae (1) to (4), or a polypeptide having a homology with the foregoing polypeptide. | 02-10-2011 |
| 20110028713 | AZA COMPOUNDS AND PRODUCTION METHOD THEREOF, AND METAL COMPLEXES AS MRI CONTRAST AGENTS - A core of a cyclic structure represented by (—N—(CH | 02-03-2011 |
| 20110021654 | NOVEL CATIONIC PHOTOPOLYMERIZATION INITIATOR - An object of the present invention is to provide a novel cationic photopolymerization initiator that efficiently absorbs light and generates protons. As a means of achieving the object above, a preferred cationic photopolymerization initiator of the present invention includes an initiator comprising a bismuthonium salt represented by the following general formula (II): | 01-27-2011 |
| 20110020851 | NOVEL GLUCOSE DEHYDROGENASE - The invention provides a glucose dehydrogenase that is an extremely stable enzyme having a thermostability of 80° C. or more, and that does not substantially act upon saccharides other than glucose (e.g., having a reactivity of less than 3% with respect to maltose, galactose, and xylose). The invention also provides a method for producing such an enzyme, and a composition for quantifying glucose using such an enzyme. | 01-27-2011 |
| 20110016967 | FLUID DISTRIBUTION DEVICE, MICRO PLANT, METHOD OF DESIGNING FLUID DISTRIBUTION DEVICE, AND METHOD OF DETECTING BLOCKAGE OF FLOW CHANNEL - The present invention provides a fluid distribution device for uniformly distributing and outputting a fluid, which is supplied to an input flow channel, into at least three output flow channels, comprising a plurality of branch flow channels, at least three fluid bifurcation portions, and at least one fluid converging portion, wherein the fluid distribution device is configured to correspond to a pressure drop compartment connection model composed of a fluid balance equation and a pressure balance equation. Furthermore, the present invention provides a micro plant using the fluid distribution device, a method of designing the fluid distribution device and a method of detecting blockage of flow channels of the fluid distribution device. | 01-27-2011 |
| 20110012050 | PIEZOELECTRIC MATERIAL - Provided is a piezoelectric material including a lead-free perovskite-type composite oxide which is excellent in piezoelectric characteristics and temperature characteristics and is represented by the general formula (1): | 01-20-2011 |
| 20110003365 | METHOD OF PREPARING INDUCED PLURIPOTENT STEM CELLS DEPRIVED OF REPROGRAMMING GENE - Provided is a method of preparing an induced pluripotent stem cell (iPS cell) deprived of a reprogramming gene, including providing an iPS cell having an expression vector wherein a loxP sequence is placed on each of the 5′ and 3′ sides of the reprogramming gene or a vector component necessary for the replication of the reprogramming gene in the same orientation, and treating the IPS cell with Cre recombinase. Also provided are an iPS cell deprived of a reprogramming gene, as obtained by the method, and a use of the iPS cell as a cell source for producing somatic cells. | 01-06-2011 |
| 20110002552 | METHOD AND APPARATUS FOR REMOVING IMAGE NOISE - An FFT analysis is performed to the image data of one frame which has been decoded, and a cutoff frequency on the assumption that the original signal has first-order attenuation characteristics is obtained each in the horizontal direction and in the vertical direction. A sampled-data H | 01-06-2011 |
| 20100303909 | PREPARATION FOR TREATING HEART DISEASE USED IN CELL THERAPY - An object of the present invention is to establish a cell transplantation method which can markedly improve the survival of grafted pluripotent stem cells and the efficiency of cardiomyocyte regeneration in cell therapy using pluripotent stem cells derived from heart tissue and can treat heart disease further effectively. Specifically, according to the present invention, enhancement in the survival of grafted pluripotent stem cells and significant improvement in the efficiency of cardiomyocyte regeneration are achieved by using, in combination, pluripotent stem cells derived from heart tissue and a hydrogel containing a basic fibroblast growth factor (bFGF) in cell therapy for heart disease. | 12-02-2010 |
| 20100298499 | NOVEL LIVING RADICAL POLYMERIZATION METHOD USING A PHOSPHORUS COMPOUND OR NITROGEN COMPOUND AS A CATALYST - A highly active and environment-friendly catalyst for use in a living radical polymerization is provided. A catalyst for use in a living radical polymerization method is provided. The catalyst comprises a central element, which is selected from nitrogen and phosphorus, and at least one halogen atom, which is bound to the central element. A monomer having a radical reactive unsaturated bond is subjected to a radical polymerization reaction in the presence of the catalyst, thereby it is possible to obtain a polymer having narrow molecular weight distribution. The present invention has the merits such as low toxicity of the catalyst, a small amount of the catalyst being required, high solubility of the catalyst in the polymerization media, mild reaction conditions, no coloration, no odor (unnecessary post-treatment of molded products). The method of the present invention is more environment-friendly and economical than other living radical polymerization methods. | 11-25-2010 |
| 20100290108 | LIGHT AMPLIFIER - A light amplifier includes first and second multi-pass amplifiers, an excitation light source, and a beam splitter. The second multi-pass amplifier includes a light attenuation portion provided in an optical path for a light pulse to travel to pass through a light amplification medium a plurality of times, for attenuating energy of the input light pulse. In addition, an excitation light pulse from the excitation light source is split by the beam splitter into two light pulses. These two pulses are input to the first and second multi-pass amplifiers, respectively. Thus, fluctuation in energy of the light pulse output from the light amplifier can be less than fluctuation in energy of the excitation light pulse. | 11-18-2010 |
| 20100268753 | INVERSE LAPLACE TRANSFORM PROGRAM, PROGRAM FOR FORMING TABLE FOR INVERSE LAPLACE TRANSFORM, PROGRAM FOR CALCULATING NUMERICAL SOLUTION OF INVERSE LAPLACE TRANSFORM, AND INVERSE LAPLACE TRANSFORM DEVICE - A table forming unit calculates, in a weighted reproducing kernel Hilbert space formed of an absolutely continuous function that is zero at an origin, solutions of simultaneous equations obtained by discretization of an integral equation of the second kind derived from Tikhonov regularization method with a weighted square integrable space used as an observation space, and forms an H table describing information including numerical solution of the integral equation of the second kind based on the solutions of the simultaneous equations. An inverse transform unit obtains, by numerical calculation, an inner product, in the weighted square integrable space, of the numerical solution of the integral equation of the second kind and a Laplace transform image multiplied by a mollifier function with reference to the H table. | 10-21-2010 |
| 20100260322 | X-RAY GENERATOR EMPLOYING HEMIMORPHIC CRYSTAL - An X-ray generator comprises a container ( | 10-14-2010 |
| 20100254172 | PWM SIGNAL GENERATOR, AND INVERTER EQUIPPED WITH THIS PWM SIGNAL GENERATOR - The PWM signal generator of the present invention generates a first pulse waveform in which a first on-time ΔT | 10-07-2010 |
| 20100248279 | SUBSTRATE PROBE, ENZYME-ACTIVITY DETECTION METHOD BY A MULTI-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE METHOD AND ENZYME-ACTIVITY IMAGING METHOD - Substrate probe capable of detecting enzyme activity with high accuracy and a method for detecting the enzyme activity by a multi nuclear magnetic resonance method using the substrate probe. Multi-dimensional nuclear magnetic resonance is performed by using a substrate probe, which is used for measuring enzyme activity by a multi-dimensional nuclear magnetic resonance method and characterized by containing a enzyme recognition site that is selectively recognized by an active-state enzyme, as at least one constitutional unit, and a group to which at least three nuclear magnetic resonance active nuclei each having a nuclear spin and a different resonance frequency are connected, being present specifically to the enzyme recognition, thereby detecting presence of the substrate probe and the enzyme activity. Alternatively, imaging of the enzyme activity is performed by a multi-dimensional nuclear resonance imaging method. | 09-30-2010 |
| 20100247444 | COMPOUND, DIAGNOSTIC AGENT, NUCLEAR MAGNETIC RESONANCE ANALYSIS METHOD, NUCLEAR MAGNETIC RESONANCE IMAGING METHOD, MASS SPECTROMETRY METHOD AND MASS SPECTROMETRY IMAGING METHOD - To produce a labeled compound for a selected biological substance not using a radioisotope atom which has a risk of exposure to radioactivity and limitation on handling time but using a stable isotope atom; and that the labeled compound can be measured with good sensitivity separably from naturally occurring compounds of the selected biological substance which are substituted with the stable isotope atom. Choline as a biological substance is labeled by substituting the nitrogen atom of the quaternary ammonium group and all the carbon atoms of the methyl group attached to the nitrogen atom with respective isotopes | 09-30-2010 |
| 20100237239 | Ion Beam Detector - In order to attain an object to realize an ion beam capable of (i) immediately determining energy of the ion beam to be generated, and (ii) measuring an ion beam in real time while carrying out laser irradiation, an ion beam detector ( | 09-23-2010 |
| 20100231095 | PIEZOELECTRIC MATERIAL, PIEZOELECTRIC DEVICE, AND METHOD OF PRODUCING THE PIEZOELECTRIC DEVICE - Provided are a bismuth-based piezoelectric material whose insulation property is improved while its performance as a piezoelectric body is not impaired and a piezoelectric device using the piezoelectric material. The piezoelectric material includes a perovskite-type metal oxide represented by the following general formula (1): | 09-16-2010 |
| 20100225314 | NUCLEAR MAGNETIC RESONANCE MEASURING METHOD - The present invention provides a method for measuring nuclear magnetic resonance that employs a compound in which a plurality of nuclei is labeled with isotopes as a probe agent, highly selectively and highly sensitively obtains a nuclear magnetic resonance signal of the above described probe agent, and can attach a spatial positional information to the above described nuclear magnetic resonance signal, and an apparatus therefore. | 09-09-2010 |
| 20100216236 | Nuclear reprogramming factor and induced pluripotent stem cells - The present invention relates to a nuclear reprogramming factor having an action of reprogramming a differentiated somatic cell to derive an induced pluripotent stem (iPS) cell. The present invention also relates to the aforementioned iPS cells, methods of generating and maintaining iPS cells, and methods of using iPS cells, including screening and testing methods as well as methods of stem cell therapy. The present invention also relates to somatic cells derived by inducing differentiation of the aforementioned iPS cells. | 08-26-2010 |
| 20100210014 | Nuclear reprogramming factor and induced pluripotent stem cells - The present invention relates to a nuclear reprogramming factor having an action of reprogramming a differentiated somatic cell to derive an induced pluripotent stem (iPS) cell. The present invention also relates to the aforementioned iPS cells, methods of generating and maintaining iPS cells, and methods of using iPS cells, including screening and testing methods as well as methods of stem cell therapy. The present invention also relates to somatic cells derived by inducing differentiation of the aforementioned iPS cells. | 08-19-2010 |
| 20100198170 | SUCTION DEVICE, SUCTION SYSTEM, AND SUCTION METHOD - A suction device according to the present invention has: an outer tube connected to a fluid supply unit on a base-end side thereof and including an opening edge section; and a suction tube provided in the outer tube and connected to a negative pressure generating unit on a base-end side thereof, the suction tube including an opening edge section, wherein an annular fluid supply passage is formed between an inner peripheral surface of the outer tube and an outer peripheral surface of the suction tube, and the opening edge section of the suction tube is placed inside the opening edge section of the outer tube toward the base-end side thereof. | 08-05-2010 |
| 20100190685 | PROGNOSTIC FACTOR IN SARCOMA, AND METASTASIS INHIBITOR - The present invention relates to uses of sarcopodin as a gene associated with distant metastasis or prognosis for survival in tumors. Specifically, the present invention provides a method of determining the risk of distant metastasis or prognosis for survival in a tumor, comprising measuring the expression level of sarcopodin in a tumor tissue. Furthermore, the present invention provides an agent for inhibiting metastasis containing a polynucleotide complementary to an mRNA that encodes sarcopodin or an expression vector capable of expressing the polynucleotide. | 07-29-2010 |
| 20100184166 | METHOD FOR PRODUCING ALKALOIDS - The present invention provides a method for producing an alkaloid, for example, reticuline, comprising providing dopamine as a substrate for a series of actions of monoamine oxidase, norcoclaurine-6-O-methyltransferase, coclaurine-N-methyltransferase and 3′-hydroxy-N-methylcoclaurine-4′-O-methyltransferase. | 07-22-2010 |
| 20100160241 | NOVEL COMPOUND HAVING GPR54 AGONISTIC ACTIVITY - The present invention provides a compound represented by the following formula (1); | 06-24-2010 |
| 20100155647 | OXYNITRIDE PIEZOELECTRIC MATERIAL AND METHOD OF PRODUCING THE SAME - Provided are an oxynitride piezoelectric material which exhibits ferroelectricity and has good piezoelectric properties and a method of producing the oxynitride piezoelectric material. The oxynitride piezoelectric material includes a tetragonal perovskite-type oxynitride represented by the following general formula (1): | 06-24-2010 |
| 20100153028 | POWDERY/GRANULAR MATERIAL FLOWABILITY EVALUATION APPARATUS AND METHOD - A powdery/granular material flowability evaluation apparatus and a powdery/granular material flowability evaluation method are provided to evaluate the flowability of a powdery/granular material in a dynamic state of the powdery/granular material. The powdery/granular material flowability evaluation apparatus (A) has a hopper ( | 06-17-2010 |
| 20100133445 | ION BEAM CONTROL APPARATUS AND METHOD - Provided are an ion beam control apparatus and a control method for controlling an ion beam energy expansion level and an ion beam size in a radial direction. An ion beam control apparatus Sa is provided with an ion beam generating unit | 06-03-2010 |
| 20100131086 | SOUND SOURCE SEPARATION SYSTEM, SOUND SOURCE SEPARATION METHOD, AND COMPUTER PROGRAM FOR SOUND SOURCE SEPARATION - An audio signal produced by playing a plurality of musical instruments is separated into sound sources according to respective instrument sounds. Each time a separation process is performed, the updated model parameter estimation/storage section | 05-27-2010 |
| 20100130603 | MEDICAMENT FOR PROPHYLACTIC AND THERAPEUTIC TREATMENT OF DERMATOSIS RESULTING FROM EXCESSIVELY ADVANCED KERATINIZATION - A medicament for prophylactic and/or therapeutic treatment of a dermatosis resulting from excessively advanced keratinization, such as non-hereditary inflammatory keratosis and hereditary congenital keratosis, which comprises a substance selected from the group consisting of a cannabinoid agonist and a vanilloid agonist as an active ingredient. | 05-27-2010 |
| 20100112601 | NOVEL MONOCLONAL ANTIBODY AND USE OF THE SAME - The present invention provides an anti-PAC1 monoclonal antibody capable of recognizing a PAC1 having a native structure, a PAC1 activity regulator (in particular, activity inhibitor) containing the antibody, a prophylactic/therapeutic agent for a disease associated with accentuation of a bioactivity of PAC1, containing the antibody, a diagnostic reagent for a disease associated with an abnormality of PAC1 activity, containing the antibody, and a screening method for a substance that regulates the expression of PAC1, using the antibody and a PAC1-expressing cell. | 05-06-2010 |
| 20100106054 | PROBE TYPE DEVICE FOR REMOVING LIVING BODY TISSUE - There is provided a probe type living body tissue removing device comprising a probe unit having a probe formed in a capillary tube shape and an opening hole portion for internally aspirating a living body tissue, and also having a dissection device arranged within the probe and dissecting the living body tissue aspirated into the probe from the opening hole portion of the probe; wherein an aspiration force supplying device for supplying aspiration force to the probe unit, and a dissection driving source supplying device for supplying power or energy for fulfilling a function of the dissection device to the probe unit are connected to the probe unit; and the probe type living body tissue removing device dissects, and aspirates and removes the living body tissue by the dissecting means while the probe is inserted into the living body tissue and the living body tissue is aspirated through the opening hole portion; and a plurality of the opening hole portions of the probe are arranged. | 04-29-2010 |
| 20100104250 | TWO-DIMENSIONAL PHOTONIC CRYSTAL - A two-dimensional photonic crystal according to the present invention includes a first layer having a dielectric first layer slab in which first layer holes having a refractive index lower than that of the first layer slab are arranged cyclically, a second layer formed on the first layer, including dielectric columns having a refractive index higher than the air arranged in the air with the same cycle as the first layer hole, and a third layer having a dielectric third layer slab in which third layer holes having a refractive index lower than that of the third layer slab are arranged cyclically. Thus, it is possible to obtain the two-dimensional photonic crystal that can create a wider complete PBG than before regardless of the polarization of light and can be manufactured easily. | 04-29-2010 |
| 20100099891 | ESTIMATION OF PROTEIN-COMPOUND INTERACTION AND RATIONAL DESIGN OF COMPOUND LIBRARY BASED ON CHEMICAL GENOMIC INFORMATION - A data processing method for an estimation of compound-protein interaction using both chemical substance information, such as a chemical property of the compound, and biological information, such as sequence information of genes to rationally and efficiently screen compounds. First space representing space coordinates of a first chemical substance group and second space representing space coordinates of a second chemical substance group are defined, and the first chemical substance group is characterized by a first characteristic amount and the second chemical substance group is characterized by a second characteristic amount, and map transformation of the coordinates of the first space and the coordinates of the second space results in the solution so as to increase the correlation between the first space and the second space using a multivariable analysis technique or a machine learning method. | 04-22-2010 |
| 20100094018 | CATALYST COMPOSITION, AND PROCESS FOR PRODUCTION OF CROSS-COUPLING COMPOUND USING THE SAME - The invention provides a catalyst composition for use in a cross-coupling reaction containing an iron or cobalt fluoride and a nitrogen-containing heterocyclic ring compound represented by General Formula (1A) or (1B), | 04-15-2010 |
| 20100091801 | Data communication system, data transmitting device, data transmitting method, data receiving device, and data receiving method - A probe transmitting section ( | 04-15-2010 |
| 20100077163 | Memory Management Method, Memory Management Apparatus, and Recording Medium Recording the Memory Management Program - In a memory management method, a memory management device, and a recording medium containing a memory management program, a main program executes a process by interrupting a process for generating a continuous usable region. When the main program writes data into a heap region during a compaction process, the memory management program judges whether the data write destination is a recording region of the object to be copied or a recording region of the copied object. If the data write destination is one of those recording regions, then the write data is written into both the recording regions of the object to be copied and the copied object. For this, even if the main program performs writing during a compaction process, it is possible to maintain consistency between data on the object to be copied and the copied object. | 03-25-2010 |
| 20100075421 | Efficient method for nuclear reprogramming - A method of preparing induced pluripotent stem cells, comprising a nuclear reprogramming step with a nuclear reprogramming factor in the presence of miRNA, wherein said miRNA has a property of providing a higher nuclear reprogramming efficiency in the presence of said miRNA than in the absence thereof. | 03-25-2010 |
| 20100062533 | Nuclear reprogramming factor and induced pluripotent stem cells - The present invention relates to a nuclear reprogramming factor having an action of reprogramming a differentiated somatic cell to derive an induced pluripotent stem (iPS) cell. The present invention also relates to the aforementioned iPS cells, methods of generating and maintaining iPS cells, and methods of using iPS cells, including screening and testing methods as well as methods of stem cell therapy. The present invention also relates to somatic cells derived by inducing differentiation of the aforementioned iPS cells. | 03-11-2010 |
| 20100055088 | CXCR4 Antagonists for Wound Healing and Re-Epithelialization - The present invention provides novel uses for CXCR4 antagonists, including specifically peptides of the T-140 family, in the treatment of skin burns and other injuries. The invention further provides methods for increasing epithelialisation in a subject in need thereof, and for preventing or inhibiting fibrosis and excessive scar formation, using peptide inhibitors of the T-140 family as well as other CXCR4 antagonists. | 03-04-2010 |
| 20100048901 | NOVEL CURCUMIN DERIVATIVE - The present invention provides a novel compound that is structurally similar to curcumin and has a suppressive effect on Aβ aggregation, a degradative effect on Aβ aggregates, an inhibitory effect on β-secretase, and a protective effect on neurons. The novel compound is a compound represented by the following general formula (Ia) or a salt thereof: | 02-25-2010 |
| 20100028973 | METHOD FOR PROLIFERATING HEPATITIS VIRUS, HOLLOW FIBER FOR CULTURING HEPATITIS VIRUS-INFECTED CELLS, AND USE THEREOF - The present invention provides (i) a method for proliferating a hepatitis virus, the method including the steps of: infecting, with the hepatitis virus, cells packed into a lumen of a hollow fiber made of a permeabilized membrane; and culturing the cells or (ii) a method for proliferating a hepatitis virus, the method including the steps of: infecting cells with the hepatitis virus; packing the cells into a lumen of a hollow fiber made of a permeabilized membrane; and culturing the cells. This provides an experimental system for infecting in vitro culture cells with a hepatitis virus such as HBV or HCV and then proliferating the hepatitis virus. | 02-04-2010 |
| 20100025617 | METAL OXIDE - Provided is a piezoelectric material excellent in piezoelectricity. The piezoelectric material includes a perovskite-type complex oxide represented by the following General Formula (1). | 02-04-2010 |
| 20100021431 | Agent for Promoting the Production of Thioredoxin - A novel pharmaceutical application of an extract from a vaccine virus-inoculated and inflamed tissue and relates to a thioredoxin production promoting agent containing the extract as an active ingredient. The extract has an excellent thioredoxin production promoting action against an oxidative stress caused by a stimulus by such as a tobacco smoke extract or hydrogen peroxide and showed a significant lung cell protective effect. Therefore, the pharmaceutical of the invention containing the extract as an active ingredient is highly useful as a preventive or therapeutic agent for a chronic obstructive lung disease considered to be mainly caused by a continuous oxidative stress such as chronic smoking and the pharmaceutical with less side effects and high safety. | 01-28-2010 |
| 20100004275 | AGENT FOR SUPPRESSING DEVELOPMENT OF TOLERANCE TO NARCOTIC ANALGESICS - A medicament for suppressing development of tolerance to analgesic effect induced by administration of a narcotic analgesic such as morphine, which comprises an antagonist of the vasopressin receptor 1b as an active ingredient. | 01-07-2010 |
| 20100002908 | Pedestrian Tracking Method and Pedestrian Tracking Device - A pedestrian tracking method and a pedestrian tracking device with a simple structure can estimate the motion of a pedestrian in images without using color information, making it possible to achieve a robust pedestrian tracking. The pedestrian tracking device ( | 01-07-2010 |
| 20090324673 | METHOD FOR PRODUCING BIOACTIVE COMPOSITES - An object of the present invention is to provide a method for producing bioactive composites having imparted thereto bioactivity, to thereby form and grow in vivo or in vitro a coating layer containing a calcium phosphate compound as the major component with a high adhesion strength on the surface of various types of porous substrates such as a porous shaped body comprising an organic polymer. The means for solving the problem is characterized by comprising at least (1) a step of immersing a porous substrate in a solution containing at least calcium ions and hydrogenphosphate ions, thereby distributing the solution to the inside of at least a part of the pores of the substrate, and (2) a step of depositing fine particles containing a calcium phosphate compound as the major component inside the pores into which the solution is introduced. | 12-31-2009 |
| 20090315432 | METAL OXIDE, PIEZOELECTRIC MATERIAL AND PIEZOELECTRIC ELEMENT - Provided are a piezoelectric material without using lead or an alkali metal, the piezoelectric material having a stable crystal structure in a wide temperature range, high insulation property, and high piezoelectric property, and a piezoelectric element using the piezoelectric material, in which the piezoelectric material is made of a metal oxide having a tetragonal crystal structure and expressed by Ba(Si | 12-24-2009 |
| 20090305950 | MULTIMER OF EXTRACELLULAR DOMAIN OF CELL SURFACE FUNCTIONAL MOLECULE - As a substance which pharmacologically regulates the function of a cell surface functional molecule, a substance which has specificity and an activity or efficacy equal or superior to an antibody and does not require an advanced production technique and facility for application thereof to a pharmaceutical product has been demanded. The invention relates to a multimer of an extracellular domain of a cell surface functional molecule, particularly a tetramer of an extracellular domain of PD-1 or PD-L1. Further, the invention relates to an application of such a tetramer as a preventive and/or therapeutic agent for cancer, cancer metastasis, immunodeficiency, an infectious disease or the like and an application of PD-1 or PD-L1 as a testing or diagnostic agent or a research agent for such a disease. | 12-10-2009 |
| 20090305409 | Liposome Capable of Effective Delivery of Given Substance Into Nucleus - Disclosed is a non-viral vector capable of delivering a given substance into the nucleus of a target cell effectively even when the target cells is a undividable cell such as a dendritic cell. A bilamellar liposome having a first lipid membrane and a second lipid membrane successively from the outside, the first lipid membrane having a membrane-fusing ability and the second lipid membrane having on its surface a nuclear transport peptide. | 12-10-2009 |
| 20090297539 | PROCESS FOR PRODUCTION OF REGULATORY T CELL - The present invention provides a method of producing a regulatory T cell, which includes culturing a peripheral CD25 | 12-03-2009 |
| 20090291302 | Method for producing nanometer-size wires and nanometer-size wire - The present invention provides a nanowire production method that is simpler than conventional nanowire production methods, and that makes it easier to control the size and shape of the nanowires by using a technique completely different from the conventional ones. A powder particle containing a metal element is divided into nanometer-size wires containing the metal element by irradiating a suspension of the powder particles with a femtosecond laser. The present invention also makes it possible to divide the nanometer-size wires thus formed into nanometer-size particles containing the metal element by irradiating further the nanometer-size wires with the femtosecond laser. | 11-26-2009 |
| 20090285255 | Two-Dimensional Photonic Crystal Surface Emitting Laser Light Source - An objective of the present invention is to provide a surface emitting laser capable of selectively generating a laser oscillation in the fundamental mode and thereby emitting a single-wavelength laser light. In a surface emitting laser including an active layer and a two-dimensional photonic crystal provided on one side of the active layer, a reflector | 11-19-2009 |
| 20090279579 | Two-dimensional photonic crystal surface-emitting laser light source - The present invention provides a two-dimensional photonic crystal surface-emitting laser light source capable of producing a beam that is not accompanied by unnecessary side lobes. A window-shaped electrode | 11-12-2009 |
| 20090279084 | Optical Sensor and Method for Manufacturing the Same - An optical sensor according to the present invention significantly enhances the sensitivity of an optical sensor for molecular measurement using light such as Surface Enhanced Raman Scattering and Plasmon Resonance Spectroscopy utilizing the local plasmon's excitation of a noble metal. By using a transparent substance deposition step for forming a large number of anisotropic nano-columns having a predetermined aspect ratio, with their longitudinal direction and transverse direction aligned, by depositing a transparent substance onto a substrate from an oblique position while periodically inverting the position and a noble metal deposition step for depositing a noble metal onto surfaces of the formed anisotropic nano-columns, it is possible to manufacture an optical sensor with very high sensitivity at very low cost. | 11-12-2009 |
| 20090276608 | MICRO PROCESSOR, METHOD FOR ENCODING BIT VECTOR, AND METHOD FOR GENERATING BIT VECTOR - In a microprocessor for pipeline processing instruction execution, dependency relationship information representing a dependency relationship of each of a plurality of instructions with all the preceding instructions is stored, and whether or not the instructions in stages after instruction issue depend on the instruction of a miss speculation is judged based on the dependency relationship information if the miss speculation occurs during the execution of the plurality of instructions in accordance with a set schedule. Thus, this microprocessor can perform a recovery processing for invalidating only the instructions in a dependency relationship at once in the case of a miss speculation in speculative scheduling. | 11-05-2009 |
| 20090270267 | Composition and method for diagnosing esophageal cancer and metastasis of esophageal cancer - This invention relates to a composition, kit, or DNA chip comprising polynucleotides and antibodies as probes for detecting, determining, or predicting the presence or metastasis of esophageal cancer, and to a method for detecting, determining, or predicting the presence or metastasis of esophageal cancer using the same. | 10-29-2009 |
| 20090269404 | Crosslinked Gelatin Gel, Multilayered Structure, Carrier for Bioactive Factor, Preparation for Release of Bioactive Factor, and Their Production Methods - A multi-layer crosslinked gelatin gel structure having a layer structure that plural layers of crosslinked gelatin gel crosslinked by irradiating gelatin or a gelatin derivative with electron beam under an oxygen-containing atmosphere are arranged adjoiningly to each other, a preparation for release of a bioactive factor with the bioactive factor contained in the multi-layer crosslinked gelatin gel structure, and production processes thereof. | 10-29-2009 |
| 20090263094 | Two-Dimensional Photonic Crystal | 10-22-2009 |
| 20090252465 | WAVEGUIDE AND RESONATOR CAPABLE OF SUPPRESSING LOSS DUE TO SKIN EFFECT - The objective of the present invention is to provide a waveguide and resonator capable of suppressing the energy loss due to the skin effect. A conductive material layer is formed in the vicinity of an inside tube in the region between an outside tube and the inside tube which share the central axis and are made of a conductive material. A spacer layer (space) is formed between the surface of the inside tube and the conductive material layer. In the spacer layer, the end is thicker than the center in the layered body of the spacer layer and the conductive material layer. With the provision of such a layered body, the energy loss due to the skin effect can be suppressed. The effect becomes more prominent with a larger difference of the thickness of the spacer layer between the center and the end. | 10-08-2009 |
| 20090246875 | Efficient method for nuclear reprogramming - This relates to a method of preparing induced pluripotent stem cells, comprising a nuclear reprogramming step with a nuclear reprogramming factor in the presence of miRNA, wherein said miRNA has a property of providing a higher nuclear reprogramming efficiency in the presence of said miRNA than in the absence thereof. | 10-01-2009 |
| 20090246212 | DEVELOPMENT OF METHOD FOR SCREENING FOR DRUG CAPABLE OF IMPROVING PRODUCTION OF REGULATORY T CELLS AND METHOD FOR PRODUCING REGULATORY T CELLS USING IMMUNOSUPPRESSIVE MACROLIDE ANTIBIOTIC - The present invention provides a screening method for a compound capable of inducing regulatory T cells, comprising the following steps: | 10-01-2009 |
| 20090233373 | MULTISITE PHOSPHORYLATED PEPTIDE (PROTEIN) RECOGNIZING COMPOUND AND DETECTION METHOD, IMAGING METHOD, ALZHEIMER'S DISEASE DIAGNOSING METHOD AND REAGENT KIT USING THE SAME - There are provided a novel compound which captures a multisite phosphorylated peptide or protein specifically to a phosphorylation site and a method for detecting a multisite phosphorylated peptide or protein using the same. In particular, there are provided a compound which specifically detects an excessively phosphorylated tau protein observed in the brain affected by Alzheimer's disease and a method for diagnosing Alzheimer's disease in vitro or in vivo using the compound. By bringing a metal complex compound having two dipicolylamine (Dpa) moieties and a spacer including a chromogenic or luminescent functional group or atom group into contact with a multisite phosphorylated peptide or protein, the compound recognizes the distance between phosphate groups and specifically binds to the peptide or the protein, and a multisite phosphorylated peptide or protein or a kinase activity is optically detected by measuring the change, or a multisite phosphorylated peptide or protein or kinase activity is imaged by an optical imaging method applying the change in the luminescence. | 09-17-2009 |
| 20090232441 | Polarized Light Mode Converter - The present invention provides a polarized light mode converter which can be provided within a two-dimensional photonic crystal or can be smoothly connected to a two-dimensional photonic crystal. In a two-dimensional photonic crystal made of a slab-like main body provided with a plurality of different refractive index regions (for example, holes | 09-17-2009 |
| 20090216821 | Singular Value Decomposition Apparatus and Singular Value Decomposition Method - The present invention provides a singular value decomposition apparatus that can perform processing in parallel at high speed and high accuracy. The singular value decomposition apparatus comprises a matrix dividing portion | 08-27-2009 |
| 20090215122 | Process for Producing Thioredoxin - An object of the present invention is to provide a process for conveniently and efficiently producing high purity thioredoxin from yeast. | 08-27-2009 |
| 20090208465 | METHOD OF TREATING NEURAL DEFECTS - The present invention provides a therapeutic agent for a nerve injury and a method for treating a nerve injury. One aspect of the invention is the method for treating a nerve injury by administering to a patient with a nerve injury a therapeutic agent for a nerve injury containing a differentiated cell-derived pluripotent cell obtained by forced expression of reprogramming genes such as a combination of the Oct3/4 gene, Sox2 gene, Klf4, and c-myc gene. in a differentiated cell; or cells obtained by inducing the aforementioned differentiated cell-derived pluripotent cells to differentiate into an embryoid body or a neurosphere. | 08-20-2009 |
| 20090203199 | ION BEAM IRRADIATING APPARATUS, AND METHOD OF PRODUCING SEMICONDUCTOR DEVICE - An ion beam irradiating apparatus has a field emission electron source | 08-13-2009 |
| 20090203134 | REMEDY FOR NERVE CELL REGENERATION | 08-13-2009 |
| 20090194236 | Plasma processing equipment - A plurality of concentric ring-shaped slots ( | 08-06-2009 |
| 20090181012 | METHOD FOR DETECTING REGULATORY T CELLS USING EXPRESSION OF FOLATE RECEPTOR 4 AS INDICATOR, METHOD FOR TREATING DISEASES USING THE DETECTION METHOD, PHARMACEUTICAL COMPOSITION FOR IMMUNOSTIMULATION, AND METHOD FOR TREATING DISEASES USING THE COMPOSTION - An object of the present invention is to provide a technique to distinguish between T | 07-16-2009 |
| 20090178966 | Process for Producing Organic Porous Material and Organic Porous Column and Organic Porous Material - An organic porous material is provided being excellent in mechanical properties such as strength and in which structures of a skeleton and pores are controlled more precisely. By a production process including (i) subjecting a low molecular compound having living radical and/or anionic polymerizability to living radical or anionic polymerization in a system including the compound, an organic polymer as a phase separation inducing component, a polymerization initiator, and a polymerization solvent, and thereby forming a gel including a skeletal phase rich in a polymer of the compound and a solvent phase rich in the solvent and having a co-continuous structure formed of the skeletal and solvent phases, and (ii) removing the solvent from the gel thus formed to form a skeleton containing the polymer as a base material thereof from the skeletal phase while forming first pores from the solvent phase, and thereby obtaining an organic porous material with a co-continuous structure formed of the skeleton and the first pores. | 07-16-2009 |
| 20090175304 | Two-Dimensional Photonic Crystal Surface Emitting Laser Light Source - A two-dimensional photonic crystal surface emitting laser light source according to the present invention includes a two-dimensional photonic crystal made of a plate-shaped body material provided with a periodic arrangement of identically-shaped holes | 07-09-2009 |
| 20090170960 | PEPTIDE LIPID-CONTAINING CARRIER AND METHOD FOR INTRODUCING COMPOUND INTO CELLS USING SAME - The present invention provides a carrier capable of highly efficiently introducing a compound into cells with low cytotoxicity, which contains peptide lipids represented by the following formula, and a method for introducing a compound into cells using the carrier: wherein R | 07-02-2009 |
| 20090162008 | POLARIZATION-INDEPENDENT TWO-DIMENSIONAL PHOTONIC CRYSTAL MULTIPLEXER/DEMULTIPLEXER - The present invention is aimed at providing a two-dimensional photonic crystal wavelength multiplexer/demultiplexer capable of multiplexing and demultiplexing both TE and TM-polarized lights. In the wavelength multiplexer/demultiplexer, first and second resonators and having the same resonance wavelength λr are provided between first and second waveguides and which are separately provided in a two-dimensional photonic crystal having a photonic band gap for the TE polarization. A first polarization converter for converting a TM-polarized light to a TE-polarized light is provided on the first waveguide | 06-25-2009 |
| 20090152430 | Brace - The object is to provide a brace which allows its installment to an object portion and its detachment therefrom to be carried out easily. In a brace including a brace body | 06-18-2009 |
| 20090151787 | Organic thin-film photoelectric conversion element and method of manufacturing the same - The objectives of the present invention are to enable the manufacturing of an organic thin-film photoelectric conversion element under normal atmosphere, improve the photoelectric conversion efficiency of the element, and enhance its durability. A hole-blocking TiO2 layer is created between the photoelectric conversion layer and the electrode by a wet process. In the manufacturing process, the hole-blocking TiO2 layer is air-dried so that it will be an amorphous layer. It is possible to provide a concentration gradient layer of PCBM/P3HT in which the PCBM concentration is higher in a region close to the hole-blocking TiO2 layer. This structure will reduce the electric resistance of that region and minimize the current loss within the photoelectric conversion element. In the vicinity of the hole-blocking TiO2 layer, the PCBM concentration is increased, which in turn makes it easier for electrons to flow into the TiO2 layer since PCBM is electrically conductive. Due to these features, the organic thin-film photoelectric conversion element having the gradient structure of the present embodiment has a high level of photoelectric conversion efficiency and good durability. | 06-18-2009 |
| 20090135869 | Surface-emitting laser light source using two-dimensional photonic crystal - The present invention intends to provide a surface-emitting laser light source using a two-dimensional photonic crystal in which the efficiency of extracting light in a direction perpendicular to the surface is high. In a laser light source provided with a two-dimensional photonic crystal layer created from a plate-shaped matrix body in which a large number of holes are periodically arranged and an active layer arranged on one side of the two-dimensional photonic crystal layer, the holes are created to be columnar with a predetermined cross-sectional shape such as a circular shape, and the main axis of each of the columnar holes is tilted to a surface of the matrix body. When provided with this two-dimensional photonic crystal layer, the surface-emitting laser source using a two-dimensional photonic crystal has a Q | 05-28-2009 |
| 20090121489 | Energy converter, flag type energy converter - An energy converter comprises a flexible plane unit | 05-14-2009 |
| 20090104401 | Method for Producing Alkylsiloxane Aerogel, Alkylsiloxane Aerogel, Apparatus for Producing Same, and Method for Manufacturing Panel Containing Same - A method for producing an alkylsiloxane aerogel of the invention includes (a) a step of letting a reaction to produce a sol and a reaction to convert the sol to a gel take place in one step by adding a silicon compound whose molecules have a hydrolysable functional group and a nonhydrolysable functional group to an acidic aqueous solution containing a surfactant, and (b) a step of drying the gel produced in the step (a). In the step (b), the gel is dried at a temperature and a pressure below the critical point of a solvent used to dry the gel. | 04-23-2009 |
| 20090101514 | Electrodeposition Method for Metals - An objective of the present invention is to provide an electrodeposition method for metals using a molten salt, which easily enables the electrodeposition of various types of metals such as refractory metals and rare earth metals. In order to solve this problem, the invention is characterized in that it is effected at the electrodeposition temperature in a range of from 100° C. to 200° C. using a molten salt of quaternary ammonium halide represented by the general formula (I) below (wherein, in the formula, R | 04-23-2009 |
| 20090079736 | INFORMATION PROCESSING APPARATUS AND PROGRAM - Conventional information processing apparatuses have the problem of not being able to simulate deformation of a three-dimensional object in real time, along with its color information. An information processing apparatus according to the present invention deforms stored first mesh information of a three-dimensional object based on a deformation instruction for instructing deformation of the three-dimensional object, to acquire second mesh information, acquires a first slice information group, which is a plurality of slice information, based on the second mesh information, determines color information of the points after deformation from stored 3D voxel information, sets new color information for the points of the first slice information group based on the determined color information of the points to acquire a second slice information group, and displays that second slice information group. With this information processing apparatus, it is possible to render deformation in the shape of a three-dimensional object in real time, along with the color information of its surface and interior. | 03-26-2009 |
| 20090078619 | Classification Apparatus For Powdery Substance - A classification apparatus including a magnetic stirrer composed of main body ( | 03-26-2009 |
| 20090078029 | Powdery/granular material flowability evaluation apparatus and method - The present invention aims to provide a powdery/granular material flowability evaluation apparatus and a powdery/granular material flowability evaluation method capable of evaluating the flowability of a powdery/granular material in a dynamic state of the powdery/granular material. A powdery/granular material flowability evaluation apparatus A according to the present invention is provided with a hopper part | 03-26-2009 |
| 20090074776 | Human FGF-21 gene and gene expression products - This invention relates to human fibroblast growth factor (hF-GF-21), and to variants thereof and to polynucleotides encoding FGF-21. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, and to methods of treating liver disease such as cirrhosis and cancer, methods of treating conditions related to thymic function, and methods of treating conditions of the testis. The invention also relates to mouse fibroblast growth factor (mFGF-21), and to variants thereof and polynucleotides encoding mFGF-21. | 03-19-2009 |
| 20090054552 | FIBER-REINFORCED COMPOSITE MATERIAL AND PROCESS FOR PRODUCING THE SAME - Disclosed is a highly transparent fiber-reinforced composite material including an assembly of cellulose fibers of 4 to 200 nm average fiber diameter impregnated with a matrix material so as to not only remedy the moisture absorbency attributed to cellulose fibers but also further improve transparency. There is provided a fiber-reinforced composite material including an assembly of cellulose fibers impregnated with a matrix material. In the fiber-reinforced composite material, hydroxyl groups of cellulose fibers are chemically modified through a reaction with one or more chemical modifiers selected from the group consisting of an acid, an alcohol, a halogenating reagent, an acid anhydride, and an isocyanate so that the ratio of a functional group introduced by the chemical modification is 5 to 40 percent by mole based on the hydroxyl groups of cellulose fibers before the chemical modification. The chemical modification of hydroxyl groups of cellulose fibers can reduce the hydrophilicity of cellulose fibers to thereby reduce the moisture absorbency of fiber-reinforced composite material. Further, the affinity between cellulose fibers and matrix material can be enhanced to thereby further improve transparency. | 02-26-2009 |
| 20090051082 | METHOD FOR PRODUCING ARTIFICIAL BONE - A method for producing an artificial bone precursor is disclosed. The method comprises: extracting a part corresponding to a cancellous bone and/or a cortical bone from digitalized three-dimensional image data of a living bone, followed by setting a center line on the part; drawing a beam or a wall having a uniform diameter or thickness along the center line to form artificial bone image data; and stacking a sintered layer by laser-sintering a powder of titanium and the like based on the artificial bone image data. The precursor is suitable for an artificial bone having excellent osteoconductivity and osteoinductivity. | 02-26-2009 |
| 20090047263 | Nuclear reprogramming factor and induced pluripotent stem cells - The present invention relates to a nuclear reprogramming factor having an action of reprogramming a differentiated somatic cell to derive an induced pluripotent stem (iPS) cell. The present invention also relates to the aforementioned iPS cells, methods of generating and maintaining iPS cells, and methods of using iPS cells, including screening and testing methods as well as methods of stem cell therapy. The present invention also relates to somatic cells derived by inducing differentiation of the aforementioned iPS cells. | 02-19-2009 |
| 20090036549 | SUBSTANCE-ENCAPSULATED CARBON NANOHORN COMPLEX AND PRODUCING METHOD THEREOF - A cap of polyamine molecules is provided on an aperture portion of carbon nanohorns having apertures formed by oxidation. The polyamine cap opens and closes according to the pH of the ambient environment, thereby controlling release of an encapsulation substance. | 02-05-2009 |
| 20090036416 | Novel CXCR4 Antagonist and Use Thereof - A novel non-peptide CXCR4 antagonist has a low molecular-weight and uses various aromatic compounds, each containing a dipicolylamine-zinc complex. This CXCR4 antagonist finds use, e.g., as an anti-HIV agent, a metastasis inhibitor for a malignant tumor, and a chronic rheumatoid arthritis treatment and/or prevention agent. | 02-05-2009 |
| 20090034566 | Photonic crystal laser - One objective of the present invention is to provide a laser device which is capable of scanning beams of a laser light of high output power at a high speed without using mechanical scanning mechanisms. A plurality of the upper electrodes | 02-05-2009 |
| 20090028770 | METHOD FOR PRODUCING IRON OXYHYDROXIDE AND ADSORBING MATERIAL COMPRISING IRON OXYHYDROXIDE - The present invention provides a method for advantageously producing an iron oxyhydroxide exhibiting excellent capability of adsorbing harmful substances, such as a phosphrous components and endocrine disrupting chemicals, which are contained in industrial wastewater, exhaust gases, etc., and an adsorbent material comprising the iron oxyhydroxide produced by the method as a main component. Specifically, the present invention provides an adsorbent material produced by a method comprising the steps of:
| 01-29-2009 |
| 20090012273 | Method of Regenerating Elastic Fiber with the Use of Dance or Factor Enhancing the Expression Thereof - The present invention provides a technique for conveniently and efficiently regenerating elastic fiber retaining a normal structure, and a technique enabling preparation of an artificial tissue comprising elastic fiber (for example, artificial skin, artificial blood vessels) that can be transplanted to humans. Specifically, the invention provides a method of producing elastic fiber, comprising culturing (for example, culturing in serum-free medium) cells having the capability of regenerating elastic fiber in the presence of DANCE and/or fibulin-4; artificial elastic fiber comprising DANCE and/or fibulin-4; an elastic fiber regenerating agent; a serum-free medium comprising DANCE and/or fibulin-4; and cells having the capability of regenerating elastic fiber, transfected with at least one of a DANCE expression vector, a fibulin-4 expression vector and a DANCE inducing factor expression vector, and the like. | 01-08-2009 |
| 20090003397 | OPTICAL DEVICE, AND SEMICONDUCTOR LASER OSCILLATOR - In an optical device, a slab layer includes an active layer sandwiched between cladding layers. The slab layer has a periodic refractive index profile structure in a two-dimensional plane, as a two-dimensional slab photonic crystal structure, and a linear defect region serving as a waveguide in the periodic refractive index profile structure. Regions having different widths of the waveguides, as segments of the waveguide, are connected in series. | 01-01-2009 |
| 20080302674 | Probe Unit, Apparatus for Identifying Nucleotide Region and Method of Identifying Nucleotide Region - A probe unit for identifying a target nucleotide region in a target nucleic acid, the unit being provided with an electrode, a probe bound to the electrode and recognizes the target nucleic acid, and a hole-transfer-inducing agent bound to the probe, wherein a nucleotide region corresponding to the target nucleotide region is located between the hole-transfer-inducing-agent-binding site and the electrode-binding end of the probe. A state of the target nucleotide region in the target nucleic acid can be identified by comparing electrochemical signal levels by energy-induced hole transfers before and after the hybridization of such a probe unit with the target nucleic acid. | 12-11-2008 |
| 20080299369 | Composite Nanosheet, Method of Producing the Same, and Method for Producing Metal Oxide Nanosheet - Various metal oxide nanosheets with uniform thickness under mild conditions and in a short time are provided. A mixed solution containing a surfactant such as laurylamine and a metal alkoxide are allowed to flow over water surface to obtain a composite nanosheet. The composite nanosheet comprises a lamella molecular film consisting of a surfactant, and a metal oxide nanosheet formed along the surface of the molecular film. If necessary, the composite nanosheet was separated and then immersed in a solvent in which the surfactant can be dissolved, to separate the metal oxide nanosheet from the molecular film. | 12-04-2008 |
| 20080280767 | Method For Producing Superconducting Wire Material - A method for producing a superconducting wire material having a high resistivity layer outside a superconducting material, which is capable of easily forming a homogeneous high resistivity layer, a superconducting wire material and a superconducting device are provided. | 11-13-2008 |
| 20080241111 | Pluripotent Stem Cell Derived from Cardiac Tissue - An object of the present invention is to provide a stem cell applicable to regenerative therapeutic method, and to provide a technique to carry out regenerative therapy using the cell. A collected cardiac tissue fragment is enzymatically treated to prepare a cell suspension. Then using the cell suspension, following steps are carried out: (1) separation of cells by the density gradient method, (2) suspension-culture in a culture medium containing fibroblast growth factor and epidermal growth factor and (3) selection and separation of cells forming a floating sphere to obtain pluripotent stem cells. Thus-obtained pluripotent stem cells are used to carry out regenerative therapy. | 10-02-2008 |
| 20080240193 | Two-dimensional photonic crystal surface-emitting laser - The two-dimensional photonic crystal surface emitting laser according to the present invention includes a semiconductor substrate, a main laser section and a reflection film. The main laser section includes a lower cladding layer, an active layer, a two-dimensional photonic crystal layer, an upper cladding layer and a contact layer, which are all deposited on the semiconductor substrate. The reflection film, which surrounds the entire side surfaces of the main laser section, is made of a thin titanium-gold film deposited by sputtering. | 10-02-2008 |
| 20080240179 | Two-dimensional photonic crystal surface-emitting laser - The two-dimensional photonic crystal surface emitting laser according to the present invention includes a number of main modified refractive index areas periodically provided in a two-dimensional photonic crystal and secondary structures each relatively located in a similar manner to each of the main modified refractive index areas. The location of the secondary structure is determined so that a main reflected light which is reflected by a main modified refractive index area and a secondary reflected light which is reflected by a secondary structure are weakened or intensified by interference. | 10-02-2008 |
| 20080227802 | Agent For Suppressing Development of Tolerance to Narcotic Analgesics - A medicament for suppressing development of tolerance to analgesic effect induced by administration of a narcotic analgesic such as morphine, which comprises an antagonist of the vasopressin receptor | 09-18-2008 |
| 20080226223 | METHOD OF MANUFACTURING A SEMICONDUCTOR DEVICE - A semiconductor device has a two-dimensional slab photonic crystal structure in which a substrate supports a sheet-like slab layer including, sequentially stacked, a lower cladding layer, an active layer, and an upper cladding layer. A periodic refractive index profile structure, in surfaces of the stacked layers, introduces a linear defect region that serves as a waveguide. A p-type region and an n-type region in the slab layer define a pn junction surface at a predetermined angle with respect to the surfaces of the stacked layers in the slab layer. | 09-18-2008 |
| 20080223794 | Pillar Structure for Separating or Capturing Target Substance - A structure having an opening communicating with an inner space is adapted for separating or capturing a substance introduced from the opening into the inner space. The structure comprises a hollow member having the inner space with the opening and plural pillars positioned mutually separately in the inner space. The pillars are formed of a material containing an inorganic oxide and different in composition from the hollow member. | 09-18-2008 |
| 20080213231 | Pluripotent Stem Cell Cloned From Single Cell Derived From Skeletal Muscle Tissue - Techniques are provided which can isolate pluripotent stem cells at high purity capable of differentiation into at least a myocardial cell to regenerate the cardiac muscle. The pluripotent stem cells at high purity capable of differentiation into at least a myocardial cell to regenerate the cardiac muscle can be isolated through the following steps: (i) collecting a skeletal muscle tissue from a mammal and enzymatically treating the obtained skeletal muscle tissue to prepare a skeletal muscle tissue-derived cell; (ii) culturing the obtained skeletal muscle tissue-derived cell in a culture medium containing an epidermal growth factor and a fibroblast growth factor; (iii) selecting and separating a colony that is floating in the culture medium. | 09-04-2008 |
| 20080206828 | Device For Introducing Substance Into Cell, Cell Clamping Device and Flow Path Forming Method - A device for introducing a substance into a cell which can realize a high-efficient external substance introduction by means of electro-poration not depending on a cell size, a cell clamping device capable of clamping a cell at many locations, and a flow path forming method capable of efficiently forming a flow path. The device for introducing a substance into a cell ( | 08-28-2008 |
