KROMATID, INC. Patent applications |
Patent application number | Title | Published |
20120088239 | Detection of Chromosomal Inversions - A method and a kit for the identification of chromosomal inversions are described. Chromosomal inversions are difficult to detect unless they are quite large. The improved ability to detect chromosomal inversions is important to a number of medical applications, such as cancer and birth defects, as examples. Reporter species are attached to oligonucleotide strands designed such that they may hybridize to portions of only one of a pair of single-stranded sister chromatids prepared by the CO-FISH procedure, as an example. If an inversion has occurred, these marker probes will be detected on the sister chromatid at the same location as the inversion on the first chromatid. | 04-12-2012 |
20110287425 | Assays to Detect Small-Scale Mutations in Individual Cells - Methods, compositions, and assays are described which are useful in identifying point mutations, identifying cancer cells, and diagnosing cancer. | 11-24-2011 |