| KREATECH BIOTECHNOLOGY B.V. Patent applications |
| Patent application number | Title | Published |
| 20110104103 | Method of conjugating therapeutic compounds to cell targeting devices via metal complexes - The present invention relates to a cell-targeting complex comprising a targeting moiety and a deliverable compound, wherein said targeting moiety and said deliverable compound are joined by means of a (transition) metal ion complex having at least a first reactive moiety for forming a coordination bond with a reactive site of said targeting moiety and having at least a second reactive moiety for forming a coordination bond with a reactive site of said deliverable compound, and wherein said deliverable compound is a therapeutic compound. | 05-05-2011 |
| 20100267056 | DIFFERENTIAL LABELLING METHOD - The invention relates to a method for differentially labelling one or more entities, together comprising distinct reactive sites. The invention further relates to an entity that has been labelled by a method according to the invention and to a diagnostic kit comprising a labelled entity and to a diagnostic kit to employ a method according to the invention. | 10-21-2010 |
| 20090023910 | Applications with and Methods for Producing Selected Interstrand Cross-Links in Nucleic Acids - The invention provides a method for stably cross-linking a first nucleic acid sequence selected for being stably cross-linked in the presence of a second nucleic acid sequence selected for not being stably cross-linked in a nucleic acid molecule. The method comprises providing a nucleic acid sequence that is complementary to the first nucleic acid sequence; hybridizing the first nucleic acid sequence to its complementary sequence; and stably cross-linking the first nucleic acid sequence to the complementary sequence. | 01-22-2009 |