| Kona Medical, Inc. Patent applications |
| Patent application number | Title | Published |
|---|
| 20130138095 | METHODS AND DEVICES TO MODULATE THE AUTONOMIC NERVOUS SYSTEM VIA THE CAROTID BODY OR CAROTID SINUS - In some embodiments, sympathetic nerves surrounding arteries or leading to organs are targeted with energy sources to correct or modulate physiologic processes. In some embodiments, different types of energy sources are utilized singly or combined with one another. In some embodiments, bioactive agents or devices activated by the energy sources are delivered to the region of interest and the energy is enhanced by such agents. | 05-30-2013 |
| 20130138018 | NERVE TREATMENT SYSTEM - A method of treatment includes delivering an agent into a patient, and providing energy inside the patient so that the energy can interact with the agent to treat a nerve. A system for treatment includes a source of agent for delivery into a patient, and an energy source for providing energy inside the patient so that the energy can interact with the agent to treat a nerve. | 05-30-2013 |
| 20130012839 | SYSTEM AND METHOD FOR TREATING A THERAPEUTIC SITE - A targeting catheter is used to locate an arteriotomy, such as is formed during a femoral artery catheterization procedure. The targeting catheter includes one or more targeting aids, such as an inflatable balloon or sensor (e.g., Doppler or temperature sensor), to locate the arteriotomy. The targeting aid may be positioned at the arteriotomy. An ultrasonic beacon on the catheter may then be located relative to a therapeutic ultrasonic applicator (e.g., by using acoustic time-of-flight) so that the focus of ultrasonic energy from the applicator can be aligned with the arteriotomy. | 01-10-2013 |
| 20120277781 | METHODS AND DEVICES TO MODULATE THE AUTONOMIC NERVOUS SYSTEM WITH ULTRASOUND - In some embodiments, sympathetic nerves surrounding arteries or leading to organs are targeted with energy sources to correct or modulate physiologic processes. In some embodiments, different types of energy sources are utilized singly or combined with one another. In some embodiments, bioactive agents or devices activated by the energy sources are delivered to the region of interest and the energy is enhanced by such agents. | 11-01-2012 |
| 20120271171 | ENERGETIC MODULATION OF NERVES - A system to modulate an autonomic nerve in a patient utilizing transcutaneous ultrasound energy delivery includes a processor comprising an input for receiving information regarding energy and power to be delivered to a treatment region containing the nerve, and an output for outputting a signal, wherein the processor is configured to determine a position of a reference target from outside the patient to localize the nerve relative to the reference target, a therapeutic energy device comprising a transducer for delivering ultrasound energy from outside the patient, a controller to control an aiming of the transducer based at least in part on the signal from the processor, and an imaging system coupled to the processor or the therapeutic energy device. | 10-25-2012 |
| 20120253239 | ENERGETIC MODULATION OF NERVES - A system for applying focused ultrasound energy to a nerve surrounding an artery of a patient includes a piezoelectric array comprising a plurality of piezoelectric elements, a controller configured to control at least a subset of the piezoelectric elements so that at least one of the piezoelectric elements in the subset is in a signal transmitting mode, in a signal sensing mode, or both, a first platform on which the piezoelectric elements are coupled and a second platform, wherein the second platform is configured to support at least a part of the patient, a programmable generator configured to generate output power for one or more of the piezoelectric elements, and a programmable processor configured to process a signal sensed by at least one of the piezoelectric elements. | 10-04-2012 |
| 20120245494 | METHODS FOR TREATMENT USING ULTRASONIC ENERGY - In some examples, nerves surrounding arteries or leading to organs are targeted with energy sources to correct or modulate physiologic processes. In some examples, different types of energy sources are utilized singly or combined with one another. In some examples, bioactive agents or devices activated by the energy sources are delivered to the region of interest and the energy is enhanced by such agents or the agents are enhanced by the energy sources. | 09-27-2012 |
| 20120238919 | NERVE TREATMENT SYSTEM - In some examples, nerves surrounding arteries or leading to organs are targeted with energy sources to correct or modulate physiologic processes. In some examples, different types of energy sources are utilized singly or combined with one another. In some examples, bioactive agents or devices activated by the energy sources are delivered to the region of interest and the energy is enhanced by such agents or the agents are enhanced by the energy sources. | 09-20-2012 |
| 20120238918 | METHODS FOR DELIVERING ENERGY TO MODULATE NEURAL STRUCTURES - In some examples, nerves surrounding arteries or leading to organs are targeted with energy sources to correct or modulate physiologic processes. In some examples, different types of energy sources are utilized singly or combined with one another. In some examples, bioactive agents or devices activated by the energy sources are delivered to the region of interest and the energy is enhanced by such agents or the agents are enhanced by the energy sources. | 09-20-2012 |
| 20120197166 | METHODS AND DEVICES TO MODULATE THE AUTONOMIC NERVOUS SYSTEM WITH ULTRASOUND - In some embodiments, sympathetic nerves surrounding arteries or leading to organs are targeted with energy sources to correct or modulate physiologic processes. In some embodiments, different types of energy sources are utilized singly or combined with one another. In some embodiments, bioactive agents or devices activated by the energy sources are delivered to the region of interest and the energy is enhanced by such agents. | 08-02-2012 |
| 20120172723 | INTRAVASCULAR CATHETER TO DELIVER UNFOCUSED ENERGY TO NERVES SURROUNDING A BLOOD VESSEL - In some examples, nerves surrounding arteries or leading to organs are targeted with energy sources to correct or modulate physiologic processes. In some examples, different types of energy sources are utilized singly or combined with one another. In some examples, bioactive agents or devices activated by the energy sources are delivered to the region of interest and the energy is enhanced by such agents or the agents are enhanced by the energy sources. | 07-05-2012 |
| 20120109023 | SYSTEMS AND METHODS TO TARGET BLOOD VESSEL ADVENTITIA WITH TRANSCUTANEOUS FOCUSED ULTRASOUND - Systems and methods for maintaining the alignment of a therapeutic ultrasound applicator to a target site are described. Overlapping ultrasound signals are sent to a target tissue site and the echo detected. An algorithm is described for detecting tissue movement relative to the applicator based on comparison of the echo with a previously stored echo. | 05-03-2012 |
| 20120109018 | ENERGETIC MODULATION OF NERVES - A system for applying high intensity ultrasound energy to a nerve surrounding an artery of a patient includes a piezoelectric array comprising a plurality of ultrasound elements, a controller configured to individually control a phasing of each of the ultrasound elements, a platform on which the ultrasound elements are coupled, wherein the platform is configured to support at least a part of the patient, a programmable generator configured to generate an output power for at least one of the ultrasound elements, and a programmable processor configured to process a signal transmitted from one of the ultrasound elements and reflected back from tissue, and determine a tissue characteristic based on the reflected signal. | 05-03-2012 |
| 20120108967 | USE OF FOCUSED ULTRASOUND FOR VASCULAR SEALING - Methods for applying heat to a region proximate a blood vessel are disclosed. In one embodiment, a method can include generating an imaging ultrasound beam adapted to image a blood vessel target and receiving a reflection of the imaging ultrasound beam. The method can also include producing an output signal in response to the reflection of the imaging ultrasonic beam and processing the output signal to identify a location of a treatment zone proximate an outer wall of the blood vessel. Therapeutic energy can be applied to the treatment zone. In some embodiments, the therapeutic ultrasound energy beam can be moved to over-scan the treatment zone. Other methods are also disclosed. | 05-03-2012 |
| 20120108966 | USE OF FOCUSED ULTRASOUND FOR VASCULAR SEALING - Methods for applying heat to a region proximate a blood vessel are disclosed. In one embodiment, a method can include generating an imaging ultrasound beam adapted to image a blood vessel target and receiving a reflection of the imaging ultrasound beam. The method can also include producing an output signal in response to the reflection of the imaging ultrasonic beam and processing the output signal to identify a location of a treatment zone proximate an outer wall of the blood vessel. Therapeutic energy can be applied to the treatment zone. In some embodiments, the therapeutic ultrasound energy beam can be moved to over-scan the treatment zone. Other methods are also disclosed. | 05-03-2012 |
| 20120065494 | ENERGETIC MODULATION OF NERVES - A method to deliver focused ultrasound energy from a position outside a skin of a patient to a nerve surrounding a blood vessel, includes placing the patient on a table in a substantially flat position, moving a transducer into a position inferior to ribs, superior to an iliac crest, and lateral to a spine of the patient, maintaining the transducer at the position relative to the patient, and delivering focused ultrasound energy through the skin of the patient without traversing bone, wherein the direction of the focused ultrasound is directed from a lower torso to an upper torso of the patient. | 03-15-2012 |
| 20120065493 | ENERGETIC MODULATION OF NERVES - A method to apply a nerve inhibiting cloud surrounding a blood vessel includes creating a treatment plan, wherein the treatment plan prescribes application of the nerve inhibiting cloud towards at least a majority portion of a circumference of a blood vessel wall, and applying the nerve inhibiting cloud towards the majority portion of the circumference of the blood vessel wall for a time sufficient to inhibit a function of a nerve that surrounds the blood vessel wall. | 03-15-2012 |
| 20120065492 | ENERGETIC MODULATION OF NERVES - A system for treatment includes a focused ultrasound energy source for placement outside a patient, wherein the focused ultrasound energy source is configured to deliver ultrasound energy towards a blood vessel with a surrounding nerve that is a part of an autonomic nervous system inside the patient, and wherein the focused ultrasound energy source is configured to deliver the ultrasound energy from outside the patient to the nerve located inside the patient to treat the nerve. | 03-15-2012 |
| 20120059259 | SYSTEM AND METHOD FOR TREATING A THERAPEUTIC SITE - A targeting catheter is used to locate an arteriotomy, such as is formed during a femoral artery catheterization procedure. The targeting catheter includes one or more targeting aids, such as an inflatable balloon or sensor (e.g., Doppler or temperature sensor), to locate the arteriotomy. The targeting aid may be positioned at the arteriotomy. An ultrasonic beacon on the catheter may then be located relative to a therapeutic ultrasonic applicator (e.g., by using acoustic time-of-flight) so that the focus of ultrasonic energy from the applicator can be aligned with the arteriotomy. | 03-08-2012 |
| 20120059258 | USE OF FOCUSED ULTRASOUND FOR VASCULAR SEALING - An ultrasonic applicator unit ( | 03-08-2012 |
| 20120022409 | ENERGETIC MODULATION OF NERVES - A system for applying focused ultrasound energy to a nerve surrounding an artery of a patient includes a piezoelectric array comprising a plurality of piezoelectric elements, a controller configured to control at least a subset of the piezoelectric elements so that at least one of the piezoelectric elements in the subset is in a signal transmitting mode, in a signal sensing mode, or both, a first platform on which the piezoelectric elements are coupled and a second platform, wherein the second platform is configured to support at least a part of the patient, a programmable generator configured to generate output power for one or more of the piezoelectric elements, and a programmable processor configured to process a signal sensed by at least one of the piezoelectric elements. | 01-26-2012 |
| 20120016226 | ENERGETIC MODULATION OF NERVES - A system to modulate an autonomic nerve in a patient utilizing transcutaneous ultrasound energy delivery includes a processor comprising an input for receiving information regarding energy and power to be delivered to a treatment region containing the nerve, and an output for outputting a signal, wherein the processor is configured to determine a position of a reference target from outside the patient to localize the nerve relative to the reference target, a therapeutic energy device comprising a transducer for delivering ultrasound energy from outside the patient, a controller to control an aiming of the transducer based at least in part on the signal from the processor, and an imaging system coupled to the processor or the therapeutic energy device. | 01-19-2012 |
| 20110319765 | ENERGETIC MODULATION OF NERVES - A system for applying focused ultrasound energy to a nerve surrounding an artery of a patient includes a piezoelectric array comprising a plurality of piezoelectric elements, a controller configured to control at least a subset of the piezoelectric elements so that at least one of the piezoelectric elements in the subset is in a signal transmitting mode, in a signal sensing mode, or both, a first platform on which the piezoelectric elements are coupled and a second platform, wherein the second platform is configured to support at least a part of the patient, a programmable generator configured to generate output power for one or more of the piezoelectric elements, and a programmable processor configured to process a signal sensed by at least one of the piezoelectric elements. | 12-29-2011 |
| 20110257561 | ENERGETIC MODULATION OF NERVES - A system for treatment of an autonomic nervous system of a patient includes a focused ultrasound energy source for placement outside the patient, wherein the focused ultrasound energy source is configured to deliver ultrasound energy towards a blood vessel with a surrounding nerve that is a part of the autonomic nervous system inside the patient, and wherein the focused ultrasound energy source is configured to deliver the ultrasound energy based on a position of an indwelling vascular catheter. | 10-20-2011 |
| 20110230796 | SYSTEM AND METHOD FOR TREATING A THERAPEUTIC SITE - A targeting catheter is used to locate an arteriotomy, such as is formed during a femoral artery catheterization procedure. The targeting catheter includes one or more targeting aids, such as an inflatable balloon or sensor (e.g., Doppler or temperature sensor), to locate the arteriotomy. The targeting aid may be positioned at the arteriotomy. An ultrasonic beacon on the catheter may then be located relative to a therapeutic ultrasonic applicator (e.g., by using acoustic time-of-flight) so that the focus of ultrasonic energy from the applicator can be aligned with the arteriotomy. | 09-22-2011 |
| 20110230763 | SYSTEM AND METHOD FOR TREATING A THERAPEUTIC SITE - A targeting catheter is used to locate an arteriotomy, such as is formed during a femoral artery catheterization procedure. The targeting catheter includes one or more targeting aids, such as an inflatable balloon or sensor (e.g., Doppler or temperature sensor), to locate the arteriotomy. The targeting aid may be positioned at the arteriotomy. An ultrasonic beacon on the catheter may then be located relative to a therapeutic ultrasonic applicator (e.g., by using acoustic time-of-flight) so that the focus of ultrasonic energy from the applicator can be aligned with the arteriotomy. | 09-22-2011 |
| 20110178445 | METHODS AND DEVICES TO TARGET VASCULAR TARGETS WITH HIGH INTENSITY FOCUSED ULTRASOUND - An ultrasonic applicator unit ( | 07-21-2011 |
| 20110178403 | METHODS AND DEVICES TO TARGET VASCULAR TARGETS WITH HIGH INTENSITY FOCUSED ULTRASOUND - An ultrasonic applicator unit ( | 07-21-2011 |
| 20110118602 | METHODS AND APPARATUS FOR FOCUSED ULTRASOUND APPLICATION - An ultrasonic applicator unit ( | 05-19-2011 |
| 20110066085 | FORMATION OF ULTRASOUND BASED HEATING REGIONS ADJACENT BLOOD VESSELS - An ultrasound system used for both imaging and delivery high intensity ultrasound energy therapy to treatment sites and a method for treating tumors and other undesired tissue within a patient's body with an ultrasound device. The ultrasound device has an ultrasound transducer array disposed on a distal end of an elongate, relatively thin shaft. In one form of the invention, the transducer array is disposed within a liquid-filled elastomeric material that more effectively couples ultrasound energy into the tumor, that is directly contacted with the device. Using the device in a continuous wave mode, a necrotic zone of tissue having a desired size and shape (e.g., a necrotic volume selected to interrupt a blood supply to a tumor) can be created by controlling at least one of the f-number, duration, intensity, and direction of the ultrasound energy administered. This method speeds the therapy and avoids continuously pausing to enable intervening normal tissue to cool. | 03-17-2011 |
| 20110021913 | USE OF FOCUSED ULTRASOUND FOR VASCULAR SEALING - An ultrasonic applicator unit ( | 01-27-2011 |
