Knu-Industry Cooperation Foundation Patent applications |
Patent application number | Title | Published |
20160002308 | MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR-DERIVED PEPTIDE AND COMPOSITION CONTAINING SAME - The present invention provides small peptide fragments derived from microphthalmia-associated transcription factor (MITF) and a pharmaceutical composition for preventing or treating melanoma comprising the same as an active ingredient. And also, the present invention provides a cosmetic composition for skin-whitening and/or for inhibiting skin pigmentation, comprising the peptide fragments as an active ingredient. | 01-07-2016 |
20150252073 | PEPTIDES HAVING NF-KB INHIBITORY ACTIVITY, OR COMPOSITION COMPRISING SAME - The present invention provides small peptide fragments derived from the NF-κB p65 subunit and a pharmaceutical or cosmetic composition comprising the same. The peptides have a NF-κB inhibitory activity, through controlling the transcription-activation of NF-κB. The peptides inhibit the expressions of pro-inflammatory mediators, which are induced by NF-κB, and also inhibit the transmigration of leukocytes, thereby exhibiting an anti-inflammatory activity. Especially, the peptides have excellent inhibitory activities against dermatitis and skin aging. And also, the peptides inhibit base membrane invasion of cancer cells, thereby exhibiting an inhibitory activity against the growth and/or metastasis of cancer cells. | 09-10-2015 |
20140242145 | CHITOSAN NANOFIBER FOR ANIONIC PROTEIN DRUG DELIVERY, METHOD OF PREPARING THE SAME, AND PHARMACEUTICAL PREPARATION FOR TRANSMUCOSAL ADMINISTRATION COMPRISING THE CHITOSAN NANOFIBER - A chitosan nanofiber for delivering an anionic protein drug, a method of preparing the same, and a pharmaceutical preparation for transmucosal administration including the chitosan nanofiber are provided. The chitosan nanofiber including an anionic protein drug in a core and chitosan in a shell is prepared by coaxial electrospinning an aqueous solution of the anionic protein drug through an inner nozzle and a solution of the chitosan or a chitosan derivative through an outer nozzle. | 08-28-2014 |
20140213769 | FUSION PROTEIN FOR SUPPRESSING CANCER CELL GROWTH AND SUPPRESSING VASCULOGENESIS, AND ANTICANCER COMPOSITION COMPRISING SAME - The present invention relates to a fusion protein resulting from the fusion of a cancer-specific antibody and an angiogenesis inhibitor, and relates to an anti-cancer composition including the same. More specifically, in the present invention, it is preferable that the cancer-specific antibody is trastuzumab or a fragment thereof, and the angiogenesis inhibitor is a VEGF-Trap. When the fusion protein according to the present invention is used, there are advantages in that angiogenesis and cancer cell growth can be effectively inhibited as compared to trastuzumab or VEGF-Trap, and side effects can also be reduced. | 07-31-2014 |
20140178762 | NEGATIVE ACTIVE MATERIAL FOR RECHARGEABLE LITHIUM BATTERY, METHOD OF PREPARING THE SAME, AND RECHARGEABLE LITHIUM BATTERY INCLUDING THE SAME - Disclosed are a negative active material for a rechargeable lithium battery including a spherically-shaped natural graphite-modified composite particle including: a spherically-shaped natural graphite particle where flake-shaped natural graphite fragments build up and assemble into a cabbage or random shape; and amorphous or semi-crystalline carbon, wherein an open gap between the flake-shaped natural graphite fragments is positioned on a surface part or inside the spherically-shaped natural graphite particle, the amorphous or semi-crystalline carbon is coated on the surface of the spherically-shaped natural graphite particle, and the amorphous or semi-crystalline carbon is present in the open gap, and thereby the open gap positioned on the surface part and inside the spherically-shaped natural graphite particle is maintained, a method of preparing the same, and a rechargeable lithium battery including the same. | 06-26-2014 |
20140065488 | METHOD OF PREPARING NEGATIVE ACTIVE MATERIAL FOR RECHARGEABLE LITHIUM BATTERY, AND NEGATIVE ACTIVE MATERIAL AND RECHARGEABLE LITHIUM BATTERY PREPARED FROM THE SAME - Disclosed are a method of preparing a negative active material for a rechargeable lithium battery that includes preparing a solution including spherically shaped natural graphite particles and a solvent, ultrasonic wave-treating the solution, and drying the ultrasonic wave-treated solution to prepare graphite modified particles, and a rechargeable lithium battery prepared therefrom. | 03-06-2014 |
20130261796 | INTELLIGENT ROBOT APPARATUS RESPONSIVE TO ENVIRONMENTAL CHANGE AND METHOD OF CONTROLLING AND RECONFIGURING INTELLIGENT ROBOT APPARATUS - Provided is a robot apparatus and a method of reconfiguring a software component and an internal environment that may autonomously optimize and reconfigure a component execution program, execution environment settings, and the like, dynamically reconfigure components using a component included in the robot or a component downloaded from a server, or optimally configure an internal configuration of the robot, in response to the provided command so that the robot apparatus may perform a provided command in response to a change in an environment by dynamically recognizing the change in the environment when an environment in which the robot is used, although the external environment or the internal environment is changed while the robot is operated. | 10-03-2013 |
20130079653 | ARRHYTHMIA DIAGNOSIS METHOD AND DEVICE - Disclosed is an arrhythmia-diagnosing method and device for diagnosing arrhythmias, such as fibrillation or tachycardia. The arrhythmia-diagnosing method includes the following steps: measuring (a) the heart characteristic length, and the (b) frequency and (c) conduction velocity of the cardiac electrical wave; and (d) determining the occurrence or absence of an arrhythmia by using the three parameters measured in steps (a) to (c). With this invention, it is possible to predict and diagnose an electrical wave tornado, one of the causes of arrhythmia, by using a non-dimensional parameter, to identify patients at risk of death or brain death due to an arrhythmia and to reduce the mortality of patients suffering from arrhythmias significantly. | 03-28-2013 |
20130055276 | TASK SCHEDULING METHOD AND APPARATUS - A task scheduling method and apparatus are provided to execute periodic tasks together with an aperiodic real-time task in a single system, to perform scheduling while satisfying a precedence relation between periodic tasks, and to perform scheduling so that an aperiodic real-time task may be efficiently executed for a residual time left after scheduling of the periodic tasks. Additionally, a component scheduling method and apparatus in robot software are provided. | 02-28-2013 |
20120021011 | ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITION COMPRISING EXTRACTS FROM BROUSSONETIA PAPYRIFERA AND LONICERA JAPONICA - The present invention relates to a pharmaceutical composition for alleviating or treating inflammations and/or pains, the pharmaceutical composition comprising extracts from | 01-26-2012 |
20100281555 | METHOD FOR MARKING BIO-INFORMATION INTO GENOME OF ORGANISM AND ORGANISM MARKED WITH THE BIO-INFORMATION - Disclosed herein is a method for marking bio-information into the genome of an organism, an organism marked with inherent bio-information by the method and a method for reading the bio-information. The method is characterized in that inherent bio-information encoded to a DNA sequence or RNA sequence is inserted into genome of organisms through a gene delivery system. Inherent bio-information is inserted into genome of organisms, thus avoiding loss by cell culture or artificial manipulation and being widely used even for organisms whose host-vector system is not provided. Based on these features, the method has the following advantages. First, inherent bio-informtion can be clearly obtained from the organisms themselves, rather than an additional means such as catalogs. Second, when organisms developed through desperate efforts are stolen, they can be tracked down and identified. Third, when serious problems occur by overuse or misuse of organisms, the origin thereof can be clearly determined. | 11-04-2010 |
20100273058 | NEGATIVE ACTIVE MATERIAL FOR LITHIUM SECONDARY BATTERY, METHOD FOR PREPARING THE SAME, NEGATIVE ELECTRODE COMPRISING THE SAME, AND LITHIUM SECONDARY BATTERY COMPRISING SAME - The present invention relates to a negative active material for a rechargeable lithium battery, a method of manufacturing the negative active material, and a rechargeable lithium battery including the negative active material. The negative active material includes a sphere-shaped first graphite particle that a first particle precursor, a flake-shaped graphite piece, is linked to each other; and at least one second particle dispersed between the flake-shaped graphite pieces inside the sphere-shaped first graphite particle and selected from the group consisting of at least one element particle selected from the group consisting of Si, Sn, Al, Ge, Pb, and combinations thereof; at least one element compound particle selected from the group consisting of Si, Sn, Al, Ge, Pb, and combinations thereof; a composite particle including at least one element selected from the group consisting of Si, Sn, Al, Ge, Pb, and combinations thereof; a carbon composite particle including at least one element selected from the group consisting of Si, Sn, Al, Ge, Pb, and combinations thereof; and a combination particle thereof. | 10-28-2010 |
20100234633 | METHODS FOR THE SYNTHESIS OF ORGANIC SULFIDES BY USING SULFIDES AND ORGANIC SULFUR-INDIUM COMPLEXES - The present invention relates to a novel synthesis method for the formation of carbon-sulfur bonds by the reaction of an organic sulfur-indium complex with nucleophile in the presence of a palladium catalyst. The present invention provides a synthesis method to prepare several kinds of organic sulfides which are difficult to be prepared by the conventional synthesis methods. A short reaction time and quantitative yield are the advantages of this method. In addition, several kinds of organic sulfide can be prepared by the selection of nucleophile and organic sulfur-indium complex to be used. | 09-16-2010 |
20100197576 | Polypeptides or fusion proteins thereof inhibiting transmigration of leucocytes or growth and/or metastasis of cancer cells - The present invention provides a polypeptide or its fusion protein derived from a paired immunoglobulin-like receptor α or β (PILRα or PILRβ), one of the transmembrane proteins, which inhibits the transmigration of leukocytes or the growth and/or metastasis of cancer cells. The present invention also provides a polynucleotide encoding the polypeptide or its fusion protein, a vector including the polynucleotide, and a transformant transformed with the vector. The present invention also provides a pharmaceutical composition for the prevention or treatment of inflammatory diseases including the polypeptide or a fusion protein thereof. The present invention also provides a pharmaceutical composition for inhibiting the growth and/or metastasis of cancer cells including the polypeptide or a fusion protein thereof. | 08-05-2010 |
20080270888 | Method For Generating Metadata For Symbolic Music of Traditional Music, and Apparatus For Coding/Decoding Multimedia Data Using the Same - Provided is a method for generating metadata for symbolic music and a music restoring apparatus employing the same, and more particularly, a method for generating metadata for ornaments existing in the Korean traditional music and an apparatus for restoring multimedia including the same. A method for generating metadata for music, which is suggested in the present invention, includes the steps of: a) generating an extensible Markup Language (XML) notation for ornaments; b) generating a complete form of metadata including the XML notation; and c) generating metadata for entire music by using the complete form of metadata and the XML notation. | 10-30-2008 |