| KEIO UNIVERSITY Patent applications |
| Patent application number | Title | Published |
|---|
| 20120122797 | PEPTIDIC COMPOUND AND USE OF SAME - An object of the present invention is to provide a novel compound having an antitumor/anticancer effect. Specifically, the present invention provides a compound represented by Formula (I), a derivative thereof or a salt of the same. In Formula (I), R | 05-17-2012 |
| 20120101391 | BLOOD VESSEL WALL ANALYZING DEVICE AND BLOOD VESSEL WALL ANALYZING METHOD - The present invention relates to a blood vessel wall analyzing apparatus provided with a structure enabling accurate measurement of plaque components in a blood vessel wall in a state that reduces the burden on a patient. In the blood vessel wall analyzing apparatus ( | 04-26-2012 |
| 20120094383 | METHODS FOR INDUCING CELL DEATH IN PLURIPOTENT STEM CELLS AND DIFFERENTIATED CELLS OTHER THAN CARDIAC MYOCYTES - The present invention has as its object developing a method that does not involve genomic modification and which yet is capable of inducing cell death in pluripotent stem cells such as embryonic stem cells and induced pluripotent stem cells, as well as in differentiated cells other than cardiomyocytes derived from pluripotent stem cells, but not in cardiomyocytes. It has been revealed that by establishing a method capable of inducing cell death in cells other than cardiomyocytes in a very efficient manner by adding a substance having no recognized inherent toxicity or cell death inducing action to the culture conditions for pluripotent stem cells and non-cardiomyocytes, the stated problem can be solved without relying upon genomic modification. | 04-19-2012 |
| 20120091211 | SEALED SEMICONDUCTOR RECORDING MEDIUM AND SEALED SEMICONDUCTOR MEMORY - The invention relates to a sealed semiconductor recording medium and a sealed semiconductor memory and provides at low cost a sealed semiconductor memory with high reliability that can allow wireless data communication to be carried out at high speed without interference. At least one semiconductor substrate is provided with a number of read only memory blocks having such a size that the maximum side is 20 mm or less in such a state that the read only memory blocks do not share a power source wire, wherein each of the above-described read only memory blocks has a coil for power reception and a coil for data communication, and data different from each other are written in the above-described read only memory blocks. | 04-19-2012 |
| 20120088816 | Head-And-Neck Tumor Proliferation Inhibitor - It is to provide a novel head-and-neck tumor proliferation inhibitor, head-and-neck tumor metastasis inhibitor and pharmaceutical composition for treating a head-and-neck tumor. The present invention is characterized by using an inhibitory substance of a microRNA whose expression increases in a head-and-neck tumor and/or a promoting substance of a microRNA whose expression decreases in a head-and-neck tumor. Preferred examples of the microRNA whose expression increases in a head-and-neck tumor include miR-455-3p, miR-455-5p, miR-130b, miR-130b*, miR-801, miR-196a, miR-21 and miR-31. Preferred examples of the microRNA whose expression decreases in a head-and-neck tumor include miR-133b, miR-145 and miR-375. | 04-12-2012 |
| 20120065695 | MEDICAL WIRE - The present invention provides a medical wire capable of significantly reducing the risk of its frontal end to puncture an anterior wall of a bone and to move out of the bone, thereby greatly improving safety of a surgery. The medical wire includes an end composed of a material that deforms to increase resistance during advancement in the bone and substantially regains initial shape during retreat from the bone. | 03-15-2012 |
| 20120064595 | Method for accumulating cells - The present invention has as an object to simplify the implant work in a series of the process from the separation of target cells by dielectrophresis to the cell cultivation and to realize a cell accumulation method that prevents bacteria contamination by bacteria. | 03-15-2012 |
| 20120064132 | ANTIBACTERIAL MEDICAL EQUIPMENT AND METHOD FOR PRODUCING THE SAME - An object of the present invention is to provide an antibacterial medical equipment which has sufficient antibacterial activity in vivo and is excellent in compatibility with living tissues, and also can maintain antibacterial activity over a long period and has high safety. | 03-15-2012 |
| 20120059488 | TRANSPLANTATION DEVICE - The present invention is intended to provide a transplantation device which can transplant a graft into a layered tissue easily and without damaging the graft or a tissue around the transplantation site. A transplantation device ( | 03-08-2012 |
| 20120041540 | STENT TO BE USED IN TUBULAR ORGAN IN VIVO - Provided is a stent to be inserted into an in vivo organ having a tubular structure that allows a degree of freedom in design and excellent mechanical flexibility. A cylinder-shaped stent is inserted to be placed and used in the inner cavity of an in vivo tubular organ, wherein: the wall of the stent has a planar mesh pattern filled with a plurality of closed cells being adjacent to each other and having congruent shapes; the closed cells have point-symmetric parallel hexagonal shapes; all closed cells circumferentially adjacent to each other are congruent and similar in shape; two closed cells adjacent to each other sharing different sides form a substantially V-shaped member; and the vertex of each folded part in the substantially V-shaped member points to the circumferential direction. | 02-16-2012 |
| 20120034374 | EXTRUSION MATERIAL SUPPLY DEVICE AND OPTICAL TRANSMISSION BODY MANUFACTURING METHOD USING THE SAME - The invention provides an extrusion material supply device suitable for use in melt extrusion molding, and a method for manufacturing an optical transmission body, in which a deterioration of an optical signal transmission loss is extremely small, and productivity intrinsic to an extrusion molding method is provided in combination. An extrusion material supply device | 02-09-2012 |
| 20120021040 | THERAPEUTIC AGENT FOR SPINAL CORD INJURIES - Disclosed is a therapeutic agent effective for the fundamental treatment of a spinal cord injury and a demyelinating disease. Specifically disclosed are a therapeutic agent for a spinal cord injury and a therapeutic agent for a demyelinating disease, each of which comprises an HGF protein as an active ingredient. | 01-26-2012 |
| 20120012822 | AROMATIC COMPOUND AND METHOD FOR PRODUCING SAME - An aromatic compound represented by the following formula (1). | 01-19-2012 |
| 20120007438 | ELECTRONIC CIRCUIT - A low-power high-speed asynchronous inductive-coupling transmission and reception technology is provided, in which a current signal of a single pulse is made to flow through a transmitting coil, and a voltage signal of a double pulse induced in an inductively-coupled receiving coil can be received asynchronously. A transmitting circuit for performing non-contact proximity communication adopts a configuration in which current flows through a first coil in a first direction for each change of a logical value of transmit data. A receiving circuit connected to a second coil coupled inductively to the first coil employs a comparator which determines an induced voltage of a double pulse induced in the second coil by current in the first direction and outputs a unipolar single pulse signal. Whenever the single pulse signal outputted by the comparator is inputted, the receiving circuit inverts the output in a sequential circuit and reproduces receive data. | 01-12-2012 |
| 20110309907 | INDUCTOR ELEMENT AND INTEGRATED CIRCUIT DEVICE - The invention relates to an inductor element and an integrated circuit device where the efficiency of use of wire materials is high and noise interference through capacitive/inductive coupling from peripheral wires is low. | 12-22-2011 |
| 20110260786 | ELECTRONIC CIRCUIT - To provide an electronic circuit that has an interposer (rewiring layer) inserted therein and an asynchronous receiver capable of properly receiving a signal. An electronic circuit includes: a first substrate having a first coil that is formed by a wire and transmits a signal and a first transmission circuit that is connected to the first coil and asynchronously outputs the signal to the first coil; a second substrate having a second coil that is formed by a wire at a position corresponding to the first coil and forms a communication channel with the first coil to receive the signal and a third coil that is connected to the second coil by a wire on the substrate and transmits the signal; and a third substrate having a fourth coil that is formed by a wire at a position corresponding to the third coil and forms a communication channel with the third coil to receive the signal and a first reception circuit that is connected to the fourth coil and asynchronously receives the signal, the first substrate, the second substrate and the third substrate being stacked on one another, and the first transmission circuit changes a current that is to be made to flow to the first coil each time a logical value of transmission data changes. | 10-27-2011 |
| 20110259743 | METHOD FOR DETERMINATION OF OXIDATIVE STRESS - Provided is a biomarker that enables easy and rapid detection of oxidative stress on a living organism and enables prevention of tissue damage or cell necrosis by drug administration, and which is a powerful marker for the study of toxicity and pharmacokinetics of various agents. Oxidative stress is determined by measuring blood concentration of ophthalmic acid, which is a substance that varies in blood depending on the variation of reduced glutathione (GSH) concentration in a biological sample with the use of an analyzer such as a capillary electrophoresis-mass spectrometer. Further, an anti-oxidative stress agent is screened by administering an anti-oxidative stress candidate agent to a non-human animal under oxidative stress conditions, measuring blood concentration of ophthalmic acid, and evaluating the degree of decrease in the ophthalmic acid concentration. | 10-27-2011 |
| 20110256561 | LIVER DISEASE MARKER, METHOD AND APPARATUS FOR MEASURING THE SAME, AND METHOD FOR ASSAYING PHARMACEUTICAL PREPARATION - A normal person (i.e. a control) and liver diseases such as drug induced liver injury, an asymptomatic hepatitis B carrier, an asymptomatic hepatitis C carrier, chronic hepatitis B, chronic hepatitis C, liver cancer, a nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), and simple steatosis (SS) are identified by measuring the concentrations of γ-Glu-X (X represents an amino acid or an amine) peptides or the levels of AST or ALT in blood and carrying out, for example, a multiple logistic regression based on the measured value. | 10-20-2011 |
| 20110255352 | ELECTRONIC CIRCUIT - An electronic circuit for which a coil | 10-20-2011 |
| 20110250684 | METHOD FOR PRODUCING NEURAL STEM CELLS - In order to provide a method for producing neural stem cells easily and quickly by inducing differentiation of somatic cells directly into neurospheres, dedifferentiation factors are introduced into somatic cells, which are then cultured in suspension in the presence of growth factors to produce the neurospheres, thereby allowing the neural stem cells to be produced quickly without establishing iPS cells. | 10-13-2011 |
| 20110250214 | DRUG DELIVERY SYSTEM TOWARD DEMYELINATING LESION AND BIOCHEMICAL MARKER OF DEMYELINATING LESION - It is intended to provide a drug delivery system toward a demyelinating lesion. It is also intended to provide a biochemical marker of a demyelinating lesion. A delivery system for a prophylactic and/or therapeutic agent for a demyelinating disease characterized in that a substance capable of specifically recognizing Contactin is conjugated to an active ingredient of a prophylactic and/or therapeutic agent for a demyelinating disease is provided. Also provided is a method of evaluating and/or differentiating a demyelinating disease, including measuring the expression of Contactin in a body fluid. | 10-13-2011 |
| 20110217326 | METHOD FOR DIAGNOSING AND/OR TREATING TUMOR - An object of the present invention is to provide methods for diagnosing and/or treating tumors using HERV-H env gene or HERV-H env protein. Specifically, tumors are diagnosed by detecting expression of HERV-H env gene; and agents for detecting the expression are used as diagnosing agents. Further, tumors are treated by inhibiting function of HERV-H env gene; and agents for inhibiting the function are used as antitumor agents. Furthermore, tumors are treated by administering a peptide having a certain sequence of HERV-H env protein and the like; and the peptide is used as a cancer vaccine. | 09-08-2011 |
| 20110213163 | TRI-SUBSTITUTED AROMATIC COMPOUND -
A compound represented by the following formula (1):
| 09-01-2011 |
| 20110213001 | PHARMACEUTICAL COMPOSITIONS - The object of the present invention is to provide a pharmaceutical composition that inhibits expression of iNOS and COX-2 without inhibiting NF-κB. The pharmaceutical composition that inhibits expression of iNOS and COX-2 without inhibiting NF-κB contains DTCM glutarimide of the Formula (I) as an effective ingredient, thereby being able to inhibit nitric oxide (NO) production and prostaglandin production. | 09-01-2011 |
| 20110201271 | ELECTRONIC CIRCUIT AND COMMUNICATION FUNCTIONALITY INSPECTION METHOD - To provide an electronic circuit capable of easily testing semiconductor chips that are inductively coupled to each other and that communicate with each other, and an inspection method performed in the electronic circuit. An electronic circuit includes: a first substrate; a first transmission coil that is formed by a wire and transmits a signal; a first transmission circuit that outputs a signal to the first transmission coil; a first reception coil that is formed by a wire at such a position that the first reception coil is inductively coupled to the first transmission coil and receives the signal from the first transmission coil; a first reception circuit that receives the signal from the first reception coil; and a first determination circuit that compares data input to the first transmission circuit and data output from the first reception circuit, the first transmission coil, the first transmission circuit, the first reception coil, the first reception circuit and the first determination circuit being mounted on the first substrate. | 08-18-2011 |
| 20110200601 | Drug Delivery to Human Tissues by Single Chain Variable Region Antibody Fragments Cloned by Phage Display - The present invention relates to the use of non-pathogenic antibodies to deliver biologically-active proteins to specific cellular and sub-cellular sites. The invention also relates to the use of non-pathogenic antibodies to deliver biologically-active, non-protein molecules to specific cellular and sub-cellular sites. | 08-18-2011 |
| 20110183912 | AGENT FOR PROMOTING NEURONAL DIFFERENTIATION AND METHOD THEREFOR - An agent for promoting neuronal differentiation of a neural stem/progenitor cell includes an inhibitor of function of a COUP-TFI protein and/or a COUP-TFII protein. To promote neuronal differentiation of a neural stem/progenitor cell, the agent is administered to the neural stem/progenitor cell to inhibit function of a COUP-TFI protein and/or a COUP-TFII protein. | 07-28-2011 |
| 20110182545 | WAVELENGTH DOMAIN OPTICAL SWITCH - To provide a waveguide type wavelength domain optical switch which makes it possible to use a cheap lens, makes it possible to correct aberration of the demultiplexed wavelengths produced in a plurality of waveguide type demultiplexing circuits, a wavelength domain optical switch is provided with: an integrated element formed by laminating three or more waveguide type demultiplexing circuits; a first lens for collecting light emitted from the integrated element; a polarization separation element for separating light emitted from the first lens into X polarization and Y polarization and emitting the X polarization and the Y polarization at different angles; a second lens for collecting the X polarization and the Y polarization; a first reflective optical phase modulator for reflecting the collected X polarization and Y polarization at any angles; a ½-wavelength plate disposed between the second lens and the first reflective optical phase modulator in order to make polarization directions of the X polarization and the Y polarization identical; and a second reflective optical phase modulator for inputting light from the first reflective optical phase modulator into one of the waveguide type demultiplexing circuits. | 07-28-2011 |
| 20110174988 | METHOD AND APPARATUS FOR QUANTITATIVE EVALUATION OF WALL ZETA-POTENTIAL, AND METHOD AND APPARATUS FOR QUANTITATIVE VISUALIZATION OF SURFACE MODIFICATION PATTERN - A first and a second fluorescent dye are mixed into a solution, the first dye being positively ionized in the solution and the second dye being negatively ionized in the solution and having different fluorescence wavelength from the first dye. The solution is flown onto a measured surface, and the surface is excited with an evanescent wave to produce a fluorescence intensity distribution of two colors. A fluorescence intensity of the surface is measured using a two-dimensional imaging element, the element providing a fluorescence intensity of each color separated from the other colors, thereby calculating a ratio of the fluorescence intensities of the colors. Using an equation expressing a relationship between the ratio of fluorescence intensities and wall zeta potential, the ratio is converted to a two-dimensional distribution of wall zeta potentials. This achieves visualizing in real time and quantitatively evaluating the two-dimensional distribution of wall zeta potentials, and surface modifications. | 07-21-2011 |
| 20110166041 | Diagnosis/Therapeutic Strategy For Gynecological Cancer by Utilizing Micro-RNA as Biomarker - Disclosed are: a method for using a particular microRNA as a biomarker for gynecological cancer; a method for the determination of gynecological cancer; a kit for the determination of gynecological cancer, and the like. The present invention is characterized in that at least one microRNA selected from the group of microRNAs consisting of miR-592, miR-629*, miR-517a, miR-205, miR-184, miR-509-5p, miR-135a*, miR-137, miR-602, miR-186*, miR-181a-2*, miR-193b*, miR-377*, miR-449b, miR-449a, miR-369-3p, miR-323-3p, miR-329, miR-299-5p, miR-34b, miR-411, miR-34c-5p, miR-376b, miR-885-5p, miR-337-3p, miR-337-5p, miR-127-3p, miR-138, miR-203, miR-488, miR-489, miR-643, miR-888, miR-424, miR-432, miR-433, miR-450a, miR-503, miR-542-3p, miR-542-5p and miR-584 is used as a biomarker for gynecological cancer. | 07-07-2011 |
| 20110156488 | ELECTRONIC CIRCUIT - An electronic circuit carries out communication by inductive coupling between chips which are stacked and mounted. The electronic circuit relays an inter-chip communication signal by a repeater which receives a signal from a transmitter to recognize a transmission source and a receiving destination, and relays a received signal when the repeater itself exists between the transmission source and the receiving destination, and does not relay the received signal when the repeater itself does not exist between the transmission source and the receiving destination. Accordingly, data can be transferred at high speed up to a chip farther than the dimensions of a coil through communications by inductive coupling between the stacked and mounted chips. | 06-30-2011 |
| 20110152178 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR INFLUENZA VIRUS INFECTION - The present invention provides a self-assembly of a compound or of a pharmaceutically acceptable salt thereof, the compound being represented by formula (I) | 06-23-2011 |
| 20110133309 | SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD THEREFOR - The invention relates to a semiconductor device and a manufacturing method for the same, and makes the rejection rate of the product after chips are stacked and mounted sufficiently low, even when the chips are selected in a conventional, simple and inexpensive wafer test. | 06-09-2011 |
| 20110123193 | LINE CONTROL METHOD IN OPTICAL NETWORK AND OPTICAL NETWORK ITSELF - In an access network using optical switches, communications between an OLT and ONUs are established without a photoelectric conversion performed at an optical switching unit. | 05-26-2011 |
| 20110114891 | INK COMPOSITION - An ink composition comprising a microparticulate fluorescent material which can emit a high brightness fluorescent light by ultraviolet ray and has a predetermined nanosize is provided. The ink composition comprises a microparticulate fluorescent material represented by the formula YVO | 05-19-2011 |
| 20110111986 | NOVEL SACCHARIDE PRIMER AND USE THEREOF - The present invention can provide a novel saccharide primer, which makes it possible to efficiently synthesize a sugar chain, and a method for using the primer. According to the present invention, the saccharide primer of the present invention is a saccharide primer having an alkenyl chain that has one or more double bonds in a position other than the alkyl chain terminal, and represented by the following general formula (I): | 05-12-2011 |
| 20110103742 | PLASMON WAVEGUIDE AND OPTICAL ELEMENT USING THE SAME - Disclosed is a plasmon waveguide including cladding ( | 05-05-2011 |
| 20110102015 | ELECTRONIC CIRCUIT DEVICE - In the electronic circuit device with stacked plural components of the same function, this invention enables to select an arbitrary component among plural components by a control element, without setting pre-determined identification information in each component. By installing a sequential logic circuit in each component, and changing a state of the sequential logic circuit by control data transmitted from the component stacked in a preceding stage or the control element, the state of the controlled component is set to a state that accepts a selection made by the control element. | 05-05-2011 |
| 20110096818 | MULTICARRIER COMMUNICATION SYSTEM - This invention provides a multi-carrier system that can separate multi-carrier certainly by improving channel response characteristics between a transmitter and a receiver, in a MIMO system increasing receiving antennas by using a fractional sampling in a receiver. The transmitter delays and transmits a part of plural transmitting signals for a time decided from a magnification of a fractional sampling and a pulse length of a transmitting signal, or a time decided with channel response characteristics from the transmitter that the receiver measured. | 04-28-2011 |
| 20110090036 | INDUCTOR ELEMENT, INTEGRATED CIRCUIT DEVICE, AND THREE-DIMENSIONAL CIRCUIT DEVICE - The invention relates to an inductor element, an integrated circuit device and a three-dimensional circuit device where a wire passes through the opening of a coil so that the efficiency in the use of wires is high. | 04-21-2011 |
| 20110084349 | THERMOELECTRIC CONVERSION DEVICE - The thermoelectric conversion efficiency of a thermoelectric conversion device is increased by increasing the figure of merit of a spin-Seebeck effect element. | 04-14-2011 |
| 20110083962 | ADSORPTION PREVENTION METHOD OF INNER-WALL-COATED CAPILLARY FOR CAPILLARY ELECTROPHORESIS, INNER-WALL-COATED CAPILLARY FOR CAPILLARY ELECTROPHORESIS, MANUFACTURING METHOD THEREOF, AND METHOD FOR SIMULTANEOUS ANALYSIS OF PHOSPHORYLATED COMPOUND AND ANION BY CAPILLARY ELECTROPHORESIS - A inner-wall-coated capillary in which a zwitterionic polymer including a phosphate group including, for example, a phosphorylcholine group, is fixed on a wall surface including, for example, silanol by ionic interaction, is obtained by flowing a polymer solution including a phospholipid polymer combining, for example, MPC and BMA or MPC and SMA, through a capillary that includes silanol on the wall surface, for example. Consequently, adsorption of phosphorylated compounds can be prevented simply and highly durably. | 04-14-2011 |
| 20110075476 | SPINTRONIC DEVICE AND INFORMATION TRANSMITTING METHOD - A concrete means for making transmission over long distances possible using a spin-wave spin current is provided in a spintronic device and an information transmitting method. | 03-31-2011 |
| 20110055939 | METHOD FOR INTRODUCING FOREIGN GENE INTO EARLY EMBRYO OF PRIMATE ANIMAL AND METHOD FOR PRODUCING TRANSGENIC PRIMATE ANIMAL COMPRISING SUCH METHOD - An object of the present invention is to provide a method for introducing a gene into an embryo for production of a human disease model primate animal using a non-human primate animal such as a marmoset. The present invention relates to a method for introducing a foreign gene into an early embryo of a non-human primate animal, which comprises placing early embryos of a non-human primate in a 0.2 M to 0.3 M sucrose solution, so as to increase the volume of the perivitelline spaces, and then injecting a viral vector containing a human foreign gene operably linked to a promoter into the perivitelline spaces of the early embryos. | 03-03-2011 |
| 20110045548 | NOVEL HYDROGEN PEROXIDE-FORMING NADH OXIDASE AND DNA ENCODING THE SAME - It is an object of the present invention to provide DNA encoding novel NADH oxidase from a microorganism belonging to the genus | 02-24-2011 |
| 20110044928 | MICROPARTICLE FILM COMPOSITION - The present invention provides a film composition effective for correcting irregularities on the skin surface, which has stretchability and flexibility as a result of crosslinkable protein microparticles in the film composition being crosslinked by transglutaminase, as well as superior air permeability and moisture evaporation properties as a result of forming a film with the crosslinkable protein microparticles. | 02-24-2011 |
| 20110040357 | COILED LIGHT DIFFUSER FOR IRRADIATION OF BIOLOGICAL TISSUE WITH LIGHT BEAM AND LIGHT-DIFFUSING DEVICE COMPRISING THE SAME - According to the present invention, a light diffuser capable of efficiently and uniformly irradiating a wide area of a biological tissue with a light beam such as a laser light beam, which can be readily produced at low cost, and a light-diffusing device comprising the same are provided. | 02-17-2011 |
| 20110039493 | ELECTRONIC CIRCUIT - By stacking and mounting a second substrate | 02-17-2011 |
| 20110033428 | METHOD FOR ISOLATING SMOOTH MUSCLE STEM CELLS - This invention relates to a method for isolating smooth muscle stem cells derived from mammalian smooth muscle comprising bringing mammalian smooth muscle cells into contact with a fluorescence-labeled anti-CD45 antibody, anti-CD34 antibody, and anti-CD49f antibody, and isolating cells that would not bind to the anti-CD45 antibody but would bind to the anti-CD34 antibody and the anti-CD49f antibody. | 02-10-2011 |
| 20110028739 | TRI-SUBSTITUTED AROMATIC COMPOUND - A compound represented by the following formula (1): | 02-03-2011 |
| 20110021347 | Molecule Recognizing Material And Process For Producing The Molecule Recognizing Material - The present invention provides a new molecular recognition material, wherein the control of morphology is possible and the selectivity and capture efficiency of the template molecule are excellent, and to provide a simple production method thereof. The molecular recognition material of the present invention is a core-shell particle, which has a shell layer on the core particle surface, and the material is characterized in that template molecules are imprinted on the above-described shell layer. And a production method of the molecular recognition material of the present invention comprising: (a) introducing an iniferter group on the core particle surface, (b) adsorbing the template molecule, after process (a), onto the core particle surface, and (c) forming the shell layer, after process (b), on the core particle surface. | 01-27-2011 |
| 20110003842 | MARKER FOR DETERMINATION OF SENSITIVITY TO ANTI-CANCER AGENT - Provided are a marker for determining sensitivity to an anticancer agent capable of distinguishing a therapeutic response of an individual patient and a novel means for a cancer therapy using the marker. The marker for determining sensitivity to an anticancer agent contains a substance in a metabolic pathway in which L-phenylalanine and/or N,N-dimethyl glycine are/is involved. | 01-06-2011 |
| 20100323034 | METHOD FOR DETERMINATION OF SENSITIVITY TO ANTI-CANCER AGENT - Provided are an marker for determining sensitivity to an anticancer agent capable of distinguishing a therapeutic response of an individual patient and a novel means for a cancer therapy using the marker. The marker for determining sensitivity to an anticancer agent contains a calcium-binding protein S100A7, S100A8, or S100A10. | 12-23-2010 |
| 20100297767 | NOVEL CELL CULTURE AND METHODS OF PRODUCING AND COLLECTING CELL MASSES USING THE SAME - The inventors of the present invention have developed a novel cell culture method with a view to providing a process by which cell masses uniform in size and properties can be produced in large quantities and with convenience, as well as a method of recovering them. | 11-25-2010 |
| 20100276770 | SPIN CURRENT THERMAL CONVERSION DEVICE AND THERMOELECTRIC CONVERSION DEVICE - The invention relates to a spin current thermal conversion device and a thermoelectric conversion device, with which a spin current is thermally generated, and its concrete application is realized. | 11-04-2010 |
| 20100261202 | METHOD FOR EFFICIENT PRODUCTION OF MONOCYTE-DERIVED MULTIPOTENT CELL (MOMC) - It is to provide a practical method for producing efficiently a large amount of MOMC, which is a multipotent cell which is very suitable for cell transplantation for organ regeneration. It was found that by culturing peripheral blood monocytes in vitro on fibronectin in the presence of SDF-1, MOMC can be produced more efficiently, and the present invention has been completed. Specifically, it is a method for producing MOMC by culturing in vitro peripheral blood monocytes expressing CD14 on fibronectin, wherein the in vitro culture is performed in the presence of SDF-1. | 10-14-2010 |
| 20100223684 | HUMANIN RECEPTOR OR HUMANIN-LIKE POLYPEPTIDE RECEPTOR - One aspect of the present invention is directed to search receptors based on the information of HN signaling pathways in order to find Humanin receptor or Humanin-like polypeptide receptor (HNR), and to reveal a mechanism of promoting or suppressing the intracellular signal transduction for neuroprotecting activity of HN and identify a compound involved in the mechanism. The aspect of the invention is directed to a method for screening of HNR agonist and HNR antagonist, to utilize the screened compound in development of a drug for the treatment of neurodegenerative disease, and to provide an assay system of AD neuronal cell death, and to provide methods for the compulsory expression of HNR gene or knocking-out of intracellular genes. | 09-02-2010 |
| 20100210023 | Salivary metabolic biomarkers for human oral cancer detection - The present invention provides a novel oral cancer and periodontal disease salivary metabolome for use in the diagnosis or for providing a prognosis for oral cancer and periodontal disease in an individual. The present invention also provides novel methods of diagnosing or providing a prognosis for oral cancer or periodontal disease by detecting metabolites found in the saliva of an individual. Finally, the present invention provides kits for the detection of salivary metabolites useful in the diagnosis or prognosis of oral cancer and periodontal disease in an individual. | 08-19-2010 |
| 20100204435 | 12-HYDROXSTEARIC ACID COPOLYMER AND METHOD FOR PRODUCING THE SAME - Manufacture, at a high yield, a new, biodegradable 12-hydroxy acid copolymer being a non-petroleum material and contributing to prevention of environmental pollution and global warming, from materials that include 12-hydroxystearic acid or derivative thereof obtained by hydrogenating ricinoleic acid which in turn is obtained from castor oil, as well as long-chain hydroxy acid that can be synthesized from plant-based seed oil, by using an immobilized lipase as a catalyst. | 08-12-2010 |
| 20100201357 | METHOD OF LOCALLY MEASURING MOBILITY OF PROTIC SOLVENT IN SAMPLE, INSTRUMENT OF LOCALLY MEASURING MOBILITY OF PROTIC SOLVENT IN SAMPLE, MEASURING INSTRUMENT LOCALLY MEASURING BEHAVIOR OF PROTIC SOLVENT IN SAMPLE BASED ON MAGNETIC - An instrument locally measuring mobility of a protic solvent in a sample | 08-12-2010 |
| 20100164780 | EVENT DETECTING APPARATUS - An event detecting apparatus capable of high-precision detection of an event even by use of a narrow-band signal comprises: a plurality of antennas | 07-01-2010 |
| 20100136319 | METHOD FOR FORMING MESOPOROUS SILICA LAYER, ITS POROUS COATING, ANTI-REFLECTION COATING, AND OPTICAL MEMBER - A method for forming a mesoporous silica layer composed of nanometer-sized, mesoporous silica particles on an optical substrate or a dense layer formed thereon, comprising the steps of (1) hydrolyzing and polycondensing alkoxysilane in a solvent containing a catalyst, a cationic surfactant and a nonionic surfactant to prepare composites comprising nanometer-sized, mesoporous silica particles and these surfactants, (2) applying a solution containing the composites to the substrate or the dense layer, (3) drying the solution to remove the solvent, and (4) removing both surfactants by baking the resultant coating at 120-250° C. in an oxygen-containing gas atmosphere, or plasma-treating it using an oxygen-containing gas. | 06-03-2010 |
| 20100120146 | ACTIVATOR OF SIGNAL TRANSDUCTION PATHWAY - The present invention is directed to providing the activator of the integrin signaling in neural stem cells or neural progenitors and the method for using the same. The activator of the integrin signaling comprises galectin-1 and can be used as a regulator that regulates maintenance, survival, or differentiation of a neural stem cells or a neural progenitor. | 05-13-2010 |
| 20100119588 | PEPTIDE FOR INHIBITION OF INFLUENZA INFECTION, INHIBITOR OF INFLUENZA INFECTION, LIPOSOME, AND PROPHYLACTIC/THERAPEUTIC AGENT FOR INFLUENZA - To provide peptides having high affinity for hemagglutinin and peptides having high inhibitory activity against influenza virus infection, as well as pharmaceutical compositions containing the peptides, the polypeptides having any one of SEQ ID NOs: 2 to 7, 9 to 10, and 12 to 18 are obtained by introducing mutation into a peptide having the sequence of ARLSPTMVHPNGAQP (peptide A-1: SEQ ID NO: 1) and screening for peptides having higher affinity for hemagglutinin. Further, the inhibitory activity of the peptide of SEQ ID NO: 3 against influenza virus infection can be enhanced by truncating SEQ ID NO: 3 in its C-terminus region with leaving ARLPR or ARLP. In addition, an influenza virus-infection inhibitor and an influenza preventive/therapeutic agent can be prepared by formulating these influenza virus receptor-binding peptides. | 05-13-2010 |
| 20100108526 | ELECTROCHEMICAL ANALYSIS METHOD USING BORON-DOPED ELECTROCONDUCTIVE DIAMOND ELECTRODE - This invention provides an electrochemical analysis method for accurately detecting a harmful substance such as arsenic contained in a solution. In the electrochemical analysis method, a working electrode and a counter electrode are disposed in an object electrolytic solution. A negative potential is applied to the working electrode to electrodeposit the electrolyte onto the surface of the working electrode and thus to form an electrodeposit. Next, the potential of the working electrode is sweeped in a positive potential direction to allow the electrodeposit to elute into the solution and, at the same time, to detect a current change upon a potential change and thus to analyze an object substance dissolved as an electrolyte in the object electrolytic solution. A boron-doped electroconductive diamond electrode or an electrode with gold deposited on its surface is used as the working electrode. | 05-06-2010 |
| 20100100361 | NUMERICAL STRUCTURE-ANALYSIS CALCULATION SYSTEM - The object is to enable the calculation of load transfer paths in case of distributed load applied to the structure with the numerical structure-analysis calculation system. The value of the parameter U** at each point is calculated according to the ratio of the complementary strain energy U at the application of load without fixing the point in the structure and the complementary strain energy U′ at the application of load with fixing one point in the structure. In the actual calculation, according to the complementary strain energy U, and the flexibility matrix C | 04-22-2010 |
| 20100097063 | METHOD FOR CHANGING SPIN RELAXATION, METHOD FOR DETECTING SPIN CURRENT AND SPINTRONICS DEVICE USING SPIN RELAXATION - The invention relates to a method for changing spin relaxation, a method for detecting a spin current, and a spintronic device using spin relaxation, and spin relaxation is changed through injection of a spin current. | 04-22-2010 |
| 20100081617 | THERAPEUTIC AGENT FOR SPINAL CORD INJURIES - Disclosed is a therapeutic agent effective for the fundamental treatment of a spinal cord injury and a demyelinating disease. Specifically disclosed are a therapeutic agent for a spinal cord injury and a therapeutic agent for a demyelinating disease, each of which comprises an HGF protein as an active ingredient. | 04-01-2010 |
| 20100074921 | CARRIER - The present invention is directed to providing a carrier which can transport a compound to a gut-associated lymphoid tissue efficiently without being degraded or digested. For that purpose, the carrier contains a coccoid cell of a gastric mucosa-damaging spiral bacterium. Preferably, the carrier is orally administered. By making this carrier carry an antigen and orally administering it, a local or a systemic immunological reaction to the antigen can be induced. | 03-25-2010 |
| 20100070438 | METHOD FOR PREDICTING INTERACTION BETWEEN PROTEIN AND CHEMICAL - The present invention has an object to provide a method for configuring a pattern recognizer using versatile, readily available data, comprehensive protein data, and comprehensive chemical data and an object to provide a method for predicting an unknown interaction of a pair by the pattern recognizer-configuring method. In particular, an interaction such as the coupling between a protein and a chemical is used as an index; at least one selected from four parameters that are the position of a peak in mass spectrum data obtained from each chemical, the set of the position and intensity of the peak, the distance between two peaks, and the set of the positions and intensities of the two peaks is vectorized for each of a first pair having a first interaction and a second pair having a second interaction; an amino acid sequence of each protein is vectorized; a vector containing elements of the vector derived from each protein and elements of the vector derived from each chemical paired with the protein is created; and a support vector machine (SVM) is applied to this vector and trained to learn them, whereby the pattern recognizer is configured so as to discriminate between a class to which the first pair belong and a class to which the second pair belong. | 03-18-2010 |
| 20100067900 | Optical waveguide-type wavelength domain switch - An optical waveguide-type wavelength domain switch includes a waveguide-type multi/demultiplexing device laminate comprising three or more laminated waveguide-type multi/demultiplexing devices, a lens system positioned on a demultiplex side of the waveguide-type multi/demultiplexing device laminate, and a reflective optical phase-modulating cell positioned on an opposite side of the waveguide-type multi/demultiplexing device laminate to the lens system. The lens system includes a lens alignment composed of plural lenses in one-to-one correspondence with the waveguide-type multi/demultiplexing devices and having a light-collecting or collimating function in the lens-aligning direction, an image-magnifying optical system having an N:1 (N>1) image-magnifying function arranged on the optical phase-modulating cell side of the lens alignment, an f-f lens (Y) arranged on the optical phase-modulating cell side of the image-magnifying optical system, and having a light-collecting or collimating function in the same direction as the lens-aligning direction of the lens alignment, and an f-f lens (X) having a light-collecting or collimating function in a perpendicular direction to the lens-aligning direction of the lens alignment. | 03-18-2010 |
| 20100062413 | METHOD OF EVALUATING IBD, AMINO ACID DATA PROCESSOR, AMINO ACID DATA-PROCESSING METHOD, AMINO ACID DATA-PROCESSING SYSTEM, AMINO-ACID DATA-PROCESSING PROGRAM AND RECORDING MEDIUM - According to the method of evaluating IBD of the present invention, amino acid concentration data on the concentration value of amino acid in blood collected from a subject to be evaluated is measured, and an inflammatory bowel disease state in the subject is evaluated based on the measured amino acid concentration data of the subject. | 03-11-2010 |
| 20100047561 | METAL OXIDE PHOSPHOR MICROPARTICLE AND PROCESS FOR PRODUCING THE SAME; UTILIZING THE SAME, DISPERSION LIQUID, FLUORESCENCE CONVERSION MEMBRANE, METHOD OF SEPARATING METAL OXIDE PHOSPHOR MICROPARTICLE, FLUORESCENT LIQUID, FLUORESCENT PASTE, PHOSPHOR AND PROCESS FOR PRODUCING THE SAME; AND FLUORESCENCE CONVERTER - In accordance with the present invention, there are provided metal oxide-based phosphor microfine particles comprising a matrix crystal made of a metal oxide and a metal element doped as an emission center into the matrix crystal, wherein the microfine particles are provided with an organic group coordinated to a surface thereof, have a small particle size as well as a high affinity to and a high dispersibility in light-transmittable resins, and are inhibited from scattering light emitted from a light source; a process for producing the metal oxide-based phosphor microfine particles; a dispersion of the metal oxide-based phosphor microfine particles; a fluorescent conversion film; a method of separating the metal oxide-based phosphor microfine particles; a fluorescent liquid; a fluorescent paste; a phosphor; a process for producing the phosphor; and a fluorescent converter. | 02-25-2010 |
| 20100034811 | THERAPEUTIC AGENTS FOR DISEASES INVOLVING CHOROIDAL NEOVASCULARIZATION - The present inventors focused on the fact that inflammation at the subretinal macular area enhances choroidal neovascularization, and developed pharmaceutical agents that suppress initiation or advancement of neovascularization by angiogenic factors such as VEGF. More specifically, the present inventors revealed that administering anti-IL-6 receptor monoclonal antibodies to mice treated with laser photocoagulation inhibits the development of choroidal neovascularization. | 02-11-2010 |
| 20100027123 | ANTI-REFLECTION COATING, OPTICAL MEMBER COMPRISING IT, AND EXCHANGE LENS UNIT AND IMAGING DEVICE COMPRISING SUCH OPTICAL MEMBER - An anti-reflection coating laminated on a substrate, wherein in a wavelength range of 400-700 nm, the substrate has a refractive index of 1.45-1.72, the first layer is based on alumina, the second to sixth layers are dense layers having refractive indices of 1.95-2.23, 1.33-1.50, 2.04-2.24, 1.33-1.50 and 1.85-2.40, respectively, the seventh layer is composed of nanometer-sized, mesoporous silica particles, and the first to seventh layers have optical thicknesses of 25.0-250.0 nm, 27.5-52.5 nm, 37.5-54.0 nm, 45.0-62.5 nm, 77.5-102.5 nm, 16.0-26.5 nm and 112.5-162.5 nm, respectively. | 02-04-2010 |
| 20090299525 | AUTONOMOUS MOVING BODY AND METHOD FOR CONTROLLING MOVEMENT THEREOF - An autonomous moving body includes: an omnidirectional moving mechanism for moving the moving body; a detecting unit for detecting an obstacle; and a movement control unit for generating a movement instruction signal for avoiding the obstacle detected by the detecting unit while maintaining a frontal direction of the moving body to be substantially constant and transmitting the generated signal to the omnidirectional moving mechanism. | 12-03-2009 |
| 20090291439 | PHOSPHATASES INVOLVED IN THE REGULATION OF CARDIOMYOCYTE DIFFERENTIATION - An object of the invention is to provide a dephosphorylation enzyme that regulates cardiomyocyte differentiation, dominant negative enzyme thereof, a gene encoding the enzyme protein and use thereof. A protein or the like consisting of any one of the following amino acid sequences (A) to (C) is used: | 11-26-2009 |
| 20090285013 | MAGNETO-RESISTANCE EFFECT ELEMENT AND MAGNETIC MEMORY DEVICE - The invention relates to a magneto-resistance effect element and a magnetic memory device. Lowering the magnetic domain wall movement current and drive at room temperature in a current induction single magnetic domain wall movement phenomenon are achieved. A magneto-resistance effect element is formed by including at least: a magnet wire | 11-19-2009 |
| 20090280511 | Methods for selecting candidate peptides presented on the surface of cancer cells following their binding to MHC class I molecules - An objective of the present invention is to provide methods for selecting candidate peptides presented on the surface of cancer cells following binding to MHC class I molecules, wherein the peptides are involved in the stimulation of T cell immunity (cellular immunity). The present inventors discovered a new principle of MHC I-mediated antigen presentation in which a T cell antigen epitope is more efficiently presented on MHC I molecules when it is positioned at the N-terminal side than when positioned at the C-terminal side. | 11-12-2009 |
| 20090275132 | METHOD FOR PURIFYING CARDIOMYOCYTES OR PROGRAMMED CARDIOMYOCYTES DERIVED FROM STEM CELLS OR FETUSES - An object of the present invention is to develop a method for purify cardiomyocytes at a high degree of purification and at a high yield from a cell mixture comprising cardiomyocytes derived from fetuses and stem cells using various features which have not been previously expected to be used for purification of cardiomyocytes or which are newly found, wherein said method is carried out without undergoing any genetic modification or without adding any special proteins or biologically active agents. | 11-05-2009 |
| 20090274370 | COMPOSITIONAL ANALYSIS METHOD, IMAGE APPARATUS HAVING COMPOSITIONAL ANALYSIS FUNCTION, COMPOSITIONAL ANALYSIS PROGRAM, AND COMPUTER-READABLE RECORDING MEDIUM - A technology is disclosed for easily executing a compositional analysis to obtain a preferred composition. Image data is acquired, the image data is analyzed, and a plurality of composition lines expressing the feature of the image data on the composition are acquired. On the composition formed of the plurality of acquired composition lines, the ratio of lengths of two sides selected from the plurality of sides in the region partitioned by the plurality of composition lines is detected to be a specified value (for example, the golden ratio). | 11-05-2009 |
| 20090274151 | BROADCAST-CONTENT TRANSMISSION APPARATUS, AND BROADCAST-CONTENT TRANSMISSION METHOD - A transmitting side ( | 11-05-2009 |
| 20090269335 | THERAPEUTIC AGENT FOR PROSTATE CANCER - The present inventors investigated the antitumor effects of anti-IL-6 receptor antibodies against prostate cancer. The result showed that the anti-IL-6 receptor antibodies had both in vivo and in vitro antitumor effects against prostate cancer. It was also revealed that the hPM1 antitumor effect is via IL-6 receptor. | 10-29-2009 |
| 20090267848 | Electronic circuit - An electronic circuit, for which a coil | 10-29-2009 |
| 20090246769 | MOLECULAR DIAGNOSIS OF OVARIAN CANCERS - A molecular diagnosis system of ovarian cancers encompasses a detection device configured to obtain a detected value of an expression amount of an apolipoprotein A1 gene in ovarian tissue as a diagnosis subject, a storage device configured to store a normal value of the expression amount of the apolipoprotein A1 gene in normal ovarian tissue, and a determination mechanism configured to determine that the ovarian tissue as the diagnosis subject is clear cell adenocarcinoma when the detected value is lower than the normal value. | 10-01-2009 |
| 20090245250 | CONTENT TRANSMITTING APPARATUS, CONTENT RECEIVING APPARATUS, CONTENT TRANSMITTING METHOD, AND CONTENT RECEIVING METHOD - A content transmitting apparatus includes a content transmitting unit ( | 10-01-2009 |
| 20090245161 | INFORMATION COMMUNICATION APPARATUS, INFORMATION TRANSMITTING APPARATUS, AND INFORMATION COMMUNICATION METHOD - An information communication apparatus ( | 10-01-2009 |
| 20090221496 | NOVEL ANTITHROMBOTIC AGENT - The present invention provides: a pharmaceutical composition comprising an albumin conjugated with polyethylene glycol; and a method of treating a human thrombosis or a human ischemic disease, comprising intravenously administering an albumin conjugated with polyethylene glycol to a patient. | 09-03-2009 |
| 20090220774 | ANTI-REFLECTION COATING AND ITS PRODUCTION METHOD - An anti-reflection coating comprising a mesoporous silica coating composed of mesoporous silica nano-particles formed on a substrate or a dense coating formed on the substrate, the mesoporous silica coating having a refractive index of more than 1.10 and 1.35 or less. | 09-03-2009 |
| 20090220422 | Drug Delivery Material - The present invention provides a drug delivery material, which is a conjugate of 1) a drug-carrying molecular assembly, 2) a linker and 3) a substance that recognizes activated platelet, injury site of blood vessel and/or inflammatory tissue, and capable of efficiently delivering a drug to a desired site, during which the drug under delivery does not affect sites other than a desired site (hence, low possibility of causing side effects), which releases the drug only at the desired site without requiring an external means and allows the drug to exhibit an effect. | 09-03-2009 |
| 20090208465 | METHOD OF TREATING NEURAL DEFECTS - The present invention provides a therapeutic agent for a nerve injury and a method for treating a nerve injury. One aspect of the invention is the method for treating a nerve injury by administering to a patient with a nerve injury a therapeutic agent for a nerve injury containing a differentiated cell-derived pluripotent cell obtained by forced expression of reprogramming genes such as a combination of the Oct3/4 gene, Sox2 gene, Klf4, and c-myc gene. in a differentiated cell; or cells obtained by inducing the aforementioned differentiated cell-derived pluripotent cells to differentiate into an embryoid body or a neurosphere. | 08-20-2009 |
| 20090202469 | Detection of inflammatory disease and composition for preventing or treatment of inflammatory disease - A novel method for detection of an inflammatory disease and a novel composition for prevention or treatment of an inflammatory disease are provided. The method for detection of an inflammatory disease comprises using RANKL and/or OPG as a marker in a biological sample. The composition for prevention or treatment of an inflammatory disease comprises RANKL and/or M-CSF as an active ingredient. | 08-13-2009 |
| 20090196388 | SIGNAL TRANSMISSION SYSTEM AND SEMICONDUCTOR INTEGRATED CIRCUIT DEVICE - Disclosed is a semiconductor integrated circuit device including a transmitting circuit and a receiving coil inductively coupled to a transmitting coil. The transmitting circuit transmits data by supplying a current through the transmitting coil not at the time of transition of data but at every rising edge or falling edge of a clock used in transmission of data. At every rising edge or falling edge of the clock, a receiving circuit captures a voltage induced in the receiving coil due to the current flowing through the transmitting coil, reproduces the transmitted data and outputs the reproduced data. | 08-06-2009 |
| 20090196312 | Integrated circuit - An integrated circuit multiplexes transmission data faster than by a system clock, and transfers a timing pulse Txclk for that multiplexing and a multiplexed signal Txdata from a transmitter chip | 08-06-2009 |
| 20090176313 | Fluorescent Compound and Labeling Agent Comprising the Same - A novel fluorescent compound having a high light fastness, high fluorescence quantum yield and sharp absorption spectrum, which emits fluorescence having a wavelength in long wavelength region, as well as its use as a labeling agent, is disclosed. In Formula [I] below, by forming a specific hetero ring(s) with R | 07-09-2009 |
| 20090168453 | SURFACE LIGHT EMITTING DEVICE AND POLARIZATION LIGHT SOURCE - A surface light emitting device includes a polarized light source that emits polarized light; and a light guide plate including a light incident surface on which the polarized light emitted from the polarized light source is made incident, and a light emitting surface that emits light, the light guide plate being made of light transmissive resin having low birefringence in which retardation is one-fourth or less of a wavelength of the polarized light. | 07-02-2009 |
| 20090140736 | METHOD AND INSTRUMENT OF LOCALLY MEASURING PROTIC SOLVENT CONTENT IN SAMPLES - Excitation-use high frequency RF generated by an RF oscillator | 06-04-2009 |
| 20090127510 | Fine particle and red fluorescence conversion medium using the same - Particles including at least a metal oxide represented by the following formula and having a number-average particle diameter of 100 nm or less; | 05-21-2009 |
| 20090125282 | NUMERICAL STRUCTURAL ANALYSIS SYSTEM BASED ON THE LOAD-TRANSFER-PATH METHOD - The purpose of this invention is to reduce the calculation time in the numerical structure analysis system based on load-transfer-path method. | 05-14-2009 |
| 20090117644 | RECOMBINANT HSV USEFUL FOR TREATMENT OF HUMAN GLIOMA - The present invention provides a recombinant HSV having the ability to specifically kill tumor cells such as human glioma cells in vivo, useful and safe for treating human glioma, etc. and that can easily put to clinical use. A new recombinant HSV, KeM345, is constructed by inserting a γ34.5 gene transcription unit, which is expressed by Musashil promoter, into a ribonucleotide reductase gene site of the genome of a herpes simplex virus (HSV) previously attenuated, by means of homologous recombination and obtained as a purified strain. Since KeM345 is a recombinant virus itself, it can not only induce viral proliferation by being transmitted to culture cells but can also induce viral replication equivalent to that of wild-type HSV, showing an excellent cytotoxic effect (cytolytic ability) selectively upon a malignant glioma. | 05-07-2009 |
| 20090053300 | MONOCLONAL ANTIBODY, GENE ENCODING THE ANTIBODY, HYBRIDOMA, PHARMACEUTICAL COMPOSITION, AND DIAGNOSTIC REAGENT - Disclosed is a monoclonal antibody which has a heavy chain variable region containing amino acid sequences depicted in SEQ ID NOs:74, 76 and 78 and a light chain variable region containing amino acid sequences depicted in SEQ ID NOs:80, 82 and 84. The monoclonal antibody can be used as a cancer therapeutic agent which acts selectively on a cancer tissue of non-small lung cancer, pancreatic cancer, gastric cancer or the like. | 02-26-2009 |
| 20090047738 | FEEDER CELL DERIVED FROM TISSUE STEM CELL - It is an object of the present invention to provide a feeder cell with less variation in quality. The present invention relates to a feeder cell derived from a tissue stem and/or progenitor cell. A method of preparation of the feeder cell, a method of preparation of a cultured cell using the feeder cell, and a cell culturing kit are also provided. | 02-19-2009 |
| 20090046621 | RELAY APPARATUS, COMMUNICATION TERMINAL, AND COMMUNICATION METHOD - A relay apparatus ( | 02-19-2009 |
| 20090029409 | METHOD FOR DETERMINATION OF OXIDATIVE STRESS - Provided is a biomarker that enables easy and rapid detection of oxidative stress on a living organism and enables prevention of tissue damage or cell necrosis by drug administration, and which is a powerful marker for the study of toxicity and pharmacokinetics of various agents. Oxidative stress is determined by measuring blood concentration of ophthalmic acid, which is a substance that varies in blood depending on the variation of reduced glutathione (GSH) concentration in a biological sample with the use of an analyzer such as a capillary electrophoresis-mass spectrometer. Further, an anti-oxidative stress agent is screened by administering an anti-oxidative stress candidate agent to a non-human animal under oxidative stress conditions, measuring blood concentration of ophthalmic acid, and evaluating the degree of decrease in the ophthalmic acid concentration. | 01-29-2009 |
| 20090016987 | Pharmaceutical composition and therapeutic method - The object of the present invention is, based on the finding of a novel effect of IL-18, to provide pharmaceutical compositions containing IL-18 and therapeutic methods, for preventing, improving, or treating inflammatory diseases such as systemic inflammatory response syndrome (SIRS). Inflammatory diseases, such as SIRS, can be prevented, improved, or treated by administering the pharmaceutical compositions according to the present invention containing IL-18 in an amount which does not bring the decreased interleukin 18 level in either plasma or liver to a higher level than normal. | 01-15-2009 |
| 20080258744 | Electronic Circuit Testing Apparatus - The present invention has an object to provide an electronic circuit testing apparatus that is preferable for testing an electronic circuit which carries out communications between substrates based on inductive coupling and is capable of testing the electronic circuit without using test pads, wherein a probe | 10-23-2008 |
| 20080248012 | Erythrocyte Function Modifying Substance - A promoter of ATP release from red blood cells, comprising a substance capable of stabilizing the structure of hemoglobin in red blood cells in its T-state; and a method of releasing ATP from red blood cells with the use of the promoter. There are further provided an inhibitor of ATP release from red blood cells, comprising a substance capable of stabilizing the structure of hemoglobin in red blood cells in its R-state; and a method of inhibiting ATP release from red blood cells with the use of the inhibitor. | 10-09-2008 |
| 20080243019 | Respiratory function measuring equipment and storage medium - A respiratory function measuring device comprises: a three-dimensional measuring unit that measures a chest movement and an abdomen movement of a breathing animal; a first measuring unit that measures a time T | 10-02-2008 |
| 20080221560 | Intravascular Diagnostic or Therapeutic Apparatus Using High-Intensity Pulsed Light - An intravascular diagnostic or therapeutic apparatus capable of removing blood in an intravascular lumen to be observed using a minimally invasive method is provided. The apparatus includes high-intensity pulsed light generating means and high-intensity pulsed light transmitting means for transmitting high-intensity pulsed light, capable of irradiating the interior of a blood vessel with high-intensity pulsed light, producing water-vapor bubbles and temporarily removing the blood in the blood vessel. | 09-11-2008 |
