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KEDRION S.P.A.

KEDRION S.P.A. Patent applications
Patent application numberTitlePublished
20110282032PROCESS FOR HIGHLY SELECTIVE PURIFICATION OF TWO PLASMA PROTEINS: VON WILLEBRAND FACTOR (VWF) AND FIBRONECTIN (FN) - There is described a chromatographic purification process that allows highly purified von Willebrand factor (vWF) and Fibronectin (Fn) to be obtained, starting from a biological fraction enriched in vWF and Fn and easily scaled up to industrial level. Chromatographic purification was obtained by a strong anionic exchange resin. The concentrates obtained have a high specific activity and, given the low content of contaminant proteins, are particularly suitable for therapeutic use.11-17-2011