| 20120214860 | METHOD OF REGULATING THE EXPRESSION LEVEL OF SURVIVAL OF MOTOR NEURON 1 (SMN1) AND DETECTING ENZYME ACTIVITY OF UBIQUITIN CARBOXYL-TERMINAL HYDROLASE L1 (UCHL1) - The present invention relates to a method of regulating the expression level of survival of motor neuron 1 (SMN1) comprising administering to a subject in need thereof a therapeutically effective amount of ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) regulator and a pharmaceutically acceptable carrier. The present invention also relates to a method of detecting enzyme activity of ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) in human fibroblasts comprising detecting protein expression level of survival of motor neuron 1 (SMN1). | 08-23-2012 |
