| Kagoshima University Patent applications |
| Patent application number | Title | Published |
| 20130078741 | IGA-BINDING PEPTIDE AND PURIFICATION OF IGA USING THE SAME - This invention relates to: a peptide which comprises an amino acid sequence consisting of 12 to 18 amino acid residues represented by (X | 03-28-2013 |
| 20130045490 | ANTIBODY AGAINST MUCIN 1 (MUC1) PROTEIN AND USE OF SAME - The present invention provides means and a method assuring the effectiveness of early diagnosis of cancers including gastric cancers. Specifically, the present invention provides an antibody, which is prepared using, as an antigen, (a) a peptide comprising at least contiguous amino acids at positions 69 to 75 in the amino acid sequence of SEQ ID NO: 2, or (b) a peptide consisting of an amino acid sequence in which one or several amino acids are deleted, substituted or added in at least contiguous amino acids at positions 69 to 75 in the amino acid sequence of SEQ ID NO: 2, and having the antigenicity of human MUC1 protein, and which is reactive with human mucin 1 (MUC1) protein. | 02-21-2013 |
| 20130045478 | NOVEL METHOD FOR ANALYZING DNA METHYLATION - This invention provides a method for efficiently detecting DNA methylation. The method for detecting DNA methylation comprises subjecting DNA to bisulfite treatment, subjecting DNA after bisulfite treatment to a first PCR, subjecting the resultant to nested PCR, and subjecting amplified DNA to denaturing gradient gel electrophoresis. | 02-21-2013 |
| 20120244634 | METHOD FOR DETECTION OF BASIC PEPTIDE AND REAGENT FOR DETECTION OF BASIC PEPTIDE - The present invention provides a method for detection of a basic peptide by mixing a sample suspected to contain the basic peptide and a reagent containing denatured albumin and detecting turbidness due to a complex of the basic peptide and denatured albumin. | 09-27-2012 |
| 20120169756 | IMAGE PROCESSING DEVICE, IMAGE PROCESSING METHOD, AND PROGRAM - A hue conversion unit ( | 07-05-2012 |
| 20120128199 | WATERMARK INFORMATION EMBEDDING DEVICE, WATERMARK INFORMATION PROCESSING SYSTEM, WATERMARK INFORMATION EMBEDDING METHOD, AND PROGRAM - The present invention provides a watermark information embedding device, a watermark information processing system, a watermark information embedding method and program that can provide a two-dimensional code enabling detection of copying. The watermark information embedding device comprises a first wavelet transform unit ( | 05-24-2012 |
| 20120127667 | HEAT SINK PACKAGE AND METHOD OF MANUFACTURING - A circuit element is arranged on an organic substrate and connected to a wiring pattern arranged on the organic substrate. An internal connection electrode is formed on a conductive support body by electroforming so as to obtain a unitary block of the internal connection electrode and the support body. Each end of each of the internal connection electrodes connected into a unitary block by the support body is connected to the wiring pattern. After the circuit element is sealed by resin, the support body is peeled off, so as to obtain individual internal connection electrodes separately and the other end of each of the internal connection electrodes is used as an external connection electrode on the front surface while the external connection electrode on the rear surface is connected to the wiring pattern. | 05-24-2012 |
| 20120106084 | Heat Pipe, Method For Manufacturing A Heat Pipe, And A Circuit Board With A Heat Pipe Function - A heat pipe for cooling an exothermic body by the vaporization and condensation of an enclosed cooling medium is disclosed. The heat pipe comprises a flat plate-like upper plate, a flat plate-like lower plate opposed to the upper plate, and a plurality of flat plate-like intermediate plates overlaid on each other between the upper plate and the lower plate and having internal through-holes. The internal through-holes formed in each of a plurality of the intermediate plates are adapted such that only part of each through-hole is overlapped on each other to form capillary tube paths, each having a cross-sectional area smaller than the cross-sectional area of the through-hole in the flat surface direction. | 05-03-2012 |
| 20120095186 | POLYION COMPLEX COMPRISING HYDROPHOBIZED POLYAMINO ACID AND USE OF THE SAME - A polyion complex (PIC) or a PIC nanoparticle that may be easily prepared, and that is finally disappeared in vivo due to its suitable biodegradability while exhibiting high stability in vivo, an immunotherapy agent comprising the PIC nanoparticle to which various antigen proteins or peptides may be easily conjugated or incorporated and/or which may be easily mixed with the antigen proteins or peptides, as well as a process for preparing thereof are provided. Specifically, a polyion complex (PIC) comprising a hydrophobized poly(acidic amino acid) and a basic polypeptide, a nanoparticle thereof having a particle shape, an immunotherapy agent comprising the PIC nanoparticle, as well as a process for preparing the PIC, comprising steps of introducing a hydrophobic amino acid to a poly(acidic amino acid) to prepare a hydrophobized poly(acidic amino acid), and dissolving the hydrophobized poly(acidic amino acid) prepared to a buffer, and it is mixed with a basic polypeptide dissolved in a buffer. | 04-19-2012 |
| 20110308772 | Heat Pipe And Electronic Device - The Present Invention provides a heat pipe and an electronic device which can efficiently cool a light emitting element arranged in an end portion, so that it is possible to efficiently mount the heat pipe in a narrow space. The heat pipe is provided with an upper plate ( | 12-22-2011 |
| 20110229487 | THERAPEUTIC AGENT COMPRISING ANTIBODY CAPABLE OF SPECIFICALLY BINDING TO HUMAN HMGB-1 AS ACTIVE INGREDIENT - Previously, it was difficult to obtain high-affinity antibodies that specifically bind to HMGB-1 but not to HMGB-2. Under this circumstance, the present inventors successfully obtained antibodies that are more reactive to HMGB-1 than to HMGB-2 by using specific peptides as an antigen. The present inventors also demonstrated that the antibodies had a HMGB-1-neutralizing activity. The present inventors administered the antibodies to amyloidosis model animals, and as a result, successfully demonstrated that the antibodies produced a significant therapeutic effect. | 09-22-2011 |
| 20110117602 | HUMAN ANTIBODY CAPABLE OF INDUCING APOPTOSIS - A human antibody that has a specific reactivity with multiple tumor cell lines including ATL cells and possesses both safety and therapeutic efficacy and a fragment of said antibody are provided. A human antibody and a fragment of said antibody that may recognize HLA-DR β chain expressed on the surface of tumor cells were obtained. In particular, it was found that a dimer of scFv (diabody) of said antibody may induce potent apoptosis in cells expressing the HLA-DR β chain. The antibody and a fragment of said antibody obtained in accordance with the present invention are useful for a detection reagent, a diagnostic and a medicament for protection or treatment of cancers including ATL and/or viral infectious diseases. | 05-19-2011 |
| 20110077204 | Agent for Targeted Drug Delivery To Cerebral Neurons - The present invention relates to targeting agents of drugs, more specifically, to targeting agents that cause drugs to be incorporated into brain neurons. The present invention further relates to medicines comprising the targeting agents and drugs. The present invention also relates to a method for targeting drugs to brain neurons. | 03-31-2011 |
| 20100216977 | THERAPEUTIC AGENT FOR INTERSTITIAL PULMONARY DISEASE COMPRISING ANTI-HMGB-1 ANTIBODY - An objective of the present invention is to provide effective methods for treating interstitial pulmonary diseases including interstitial pneumonia such as IPF. The present invention suggests that antibodies against HMGB-1 are effective for treating pulmonary fibrosis. Thus, the present invention provides preparations which comprise an anti-HMGB-1 antibody for treating interstitial pulmonary diseases. | 08-26-2010 |
| 20100173277 | Agent for Suppressing Rejection in Organ Transplantation Comprising Anti-HMGB-1 Antibody - An objective of the present invention is to provide effective methods for suppressing rejection in organ transplantation, in particular, pancreatic islet transplantation which is useful in treating diabetes. The present invention demonstrated that antibodies against HMGB-1 suppressed the rejection in pancreatic islet transplantation and promoted the survival of grafted pancreatic islets. Thus, the present invention provides agents that comprise an anti-HMGB-1 antibody for suppressing rejection in organ transplantation. | 07-08-2010 |
| 20100063394 | OSTEOPOROSIS PROGRESS STAGE MEASURING DEVICE AND OSTEOPOROSIS PROGRESS STAGE MEASURING METHOD - An osteoporosis progress stage measuring device is configured such that an ultrasonic wave oscillating section ( | 03-11-2010 |
| 20090133082 | AUDIO/VIDEO COMMUNICATION SYSTEM - An audio/video communication system includes a large number of nodes connected in a balanced binary tree structure. In constructing a group in a balanced binary tree structure, a root node performs the following process: if a left lower node connector of the root node is vacant, the root node connects a new node to the left lower node connector and increases left weight information by “1”; if the left lower node connector of the root node is occupied and if a right lower node connector of the root node is vacant, the root node connects a new node to the right lower node connector and increases right weight information by “1”; if both of the left lower node connector and the right lower node connector of the root node are occupied and if the left weight information of the root node is equal to or less than the right weight information of the root node, the root node sends a request for an addition of a new node to its left lower node and increases the left weight information by “1”; or if both of the left lower node connector and the right lower node connector of the root node are occupied and if the left weight information of the root node is greater than the right weight information of the root node, the root node sends a request for an addition of a new node to its right lower node and increases the right weight information by “1”. Accordingly, it is possible to provide an audio/video communication system that permits simultaneous communication among a large number of nodes and that performs flexible management of adding a new node to the system and removing a node from the system. | 05-21-2009 |
| 20090054596 | Composite Particulate and Manufacturing Method for the Same - A temperature-responsive polymer (hydrated graft structure) layer ( | 02-26-2009 |