| KABUSHIKI KAISHA YAKULT HONSHA Patent applications |
| Patent application number | Title | Published |
|---|
| 20130095073 | SKIN PROPERTIES IMPROVING AGENT FOR ORAL ADMINISTRATION - Disclosed is a skin property-improving agent which exerts excellent effects by oral administration. The skin property-improving agent for oral administration contains, as an active ingredient, a bacterium belonging to the genus | 04-18-2013 |
| 20130064928 | NOVEL LACTOBACILLUS CLASSIFIED AS LACTOBACILLUS PLANTARUM, AND USE THEREOF - Disclosed is a novel lactic acid bacterium belonging to | 03-14-2013 |
| 20130042575 | CONTINUOUS ROTARY TYPE FILLING AND PACKING MACHINE PROVIDED WITH PRINTING MECHANISM - A high-speed continuous rotary type filling and packaging machine can identifies a defective filling head and a defective seal head and it also identify which part of a seal working surface in the seal head has a defect. In a sealing device of the high-seed continuous rotary type filling and packaging machine that covers a container body, which is filled with liquid contents, with a molded lid and seals the container body and the molded lid to produce a sealed container, a filling head number and a seal head number are inkjet-printed, desirably transparent ink, which can be read by irradiation of an ultraviolet ray, on a container body in which a seal working surface in the seal head and the top surface of the container molded lid are brought into press-contact and a positional relation between a seal working surface and the sealed container is fixed. | 02-21-2013 |
| 20130036709 | LID SHAPING DEVICE - The lid shaping device includes: container placing table | 02-14-2013 |
| 20130036708 | CONTINUOUS ROTARY FILLING AND PACKAGING MACHINE - A continuous rotary filling and packaging machine covers a container body with a molded lid and ultrasonically seals the container body. The molded lid to produce a sealed container includes a lid detecting device | 02-14-2013 |
| 20120329059 | METHOD FOR CONSTRUCTING NOVEL BACTERIUM BELONGING TO THE GENUS BIFIDOBACTERIUM - A method for producing bacteria belonging to the genus | 12-27-2012 |
| 20120302524 | 1,3,4-OXADIAZOLE-2-CARBOXAMIDE COMPOUND - Provided is a 1,3,4-oxadiazole-2-carboxamide compound which has STAT3 inhibitory activity and is useful as an anticancer agent. Provided is a 1,3,4-oxadiazole-2-carboxamide compound represented by formula (I) or a pharmacologically acceptable salt thereof (in the formula, Ar represents a furyl group or the like; R | 11-29-2012 |
| 20120220618 | ANTICANCER AGENT SENSITIVITY-DETERMINING MARKER - To provide a marker for determining sensitivity of a patient to an anti-cancer agent, and novel cancer therapeutic means employing the marker. | 08-30-2012 |
| 20120220613 | METHOD FOR DETERMINING SENSITIVITY TO AN ANTICANCER AGENT - To provide a marker for determining sensitivity of a patient to an anti-cancer agent, and novel cancer therapeutic means employing the marker. | 08-30-2012 |
| 20120214831 | METHOD FOR DETERMINATION OF SENSITIVITY TO ANTI-CANCER AGENT - To provide a marker for determining sensitivity of a patient to an anti-cancer agent, and novel cancer therapeutic means employing the marker. | 08-23-2012 |
| 20120201797 | AGENT FOR REDUCING RISK OF DEVELOPING CANCER - Provided is an agent or a food or drink for reducing the risk of developing breast cancer. An agent for reducing the risk of developing breast cancer which comprises a composition containing living cells of | 08-09-2012 |
| 20120142926 | Process for Production of Camptothecin Derivative - Disclosed is a process for production of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin from a camptothecin composition containing 18,19-dehydrocamptothecin without producing any vinyl form of the compound. The process is characterized by catalytically reducing at least one compound selected from a compound (1) and others in the process of producing a compound (5) from a composition containing the compound (1). | 06-07-2012 |
| 20120129880 | METHOD FOR DETERMINING SENSITIVITY TO IRINOTECAN AND USE THEREOF - To provide a method for determining the sensitivity of a patient to irinotecan, SN-38, and/or a salt thereof, which method can determine the therapeutic response of the patient and to provide a novel cancer therapeutic means employing the method. | 05-24-2012 |
| 20120067765 | Method For Producing Food Filled and Sealed Container - It is a method for producing a food-filled and sealed container having a high product value, in which a container lid made of resin is not deformed after sealing. In this method for producing a food-filled and sealed container, after a food is filled in a container body ( | 03-22-2012 |
| 20120041204 | PROCESS FOR PRODUCING TRICYCLIC KETONE - In order to efficiently supply CPT, which is a starting compound of irinotecan hydrochloride and a variety of camptothecin derivatives, by a practical total synthesis, the invention provides a means of efficiently preparing a tricyclic ketone that corresponds to a CDE ring moiety of a camptothecin (CPT) skeleton. | 02-16-2012 |
| 20120040054 | METHOD FOR CULTURING LACTIC ACID BACTERIA, AND A FOOD AND DRINK PRODUCT - The object of the present invention is to provide a method of culturing lactic acid bacteria to obtain a lactic acid bacteria culture in which the number of lactic acid bacteria can be stably maintained, and to obtain food and drink products comprising a lactic acid bacteria culture excellent in product stability. | 02-16-2012 |
| 20120021418 | GENE THAT IMPARTS OXYGEN RESISTANCE AND APPLICATION THEREOF - To provide a gene useful for imparting oxygen resistance to a microorganism and use of the gene. | 01-26-2012 |
| 20110318309 | EQUOL-PRODUCING BACTERIUM AND USE THEREOF - The present invention is directed to a microorganism having an ability of converting daidzein to equol in 24 hours of 50% or higher; a food/beverage or pharmaceutical composition containing the microorganism; an equol production method employing the microorganism; and a nucleic acid fragment which can specifically detect the microorganism. | 12-29-2011 |
| 20110201638 | PHENANTHROINDOLIZIDINE COMPOUND AND NFkB INHIBITOR CONTAINING SAME AS ACTIVE INGREDIENT - A novel compound having an excellent NFκB inhibitory effect is provided and specifically disclosed is a compound represented by the following formula (1) or a salt thereof: | 08-18-2011 |
| 20110201637 | PHENANTHROINDOLIZIDINE DERIVATIVE AND NFKB INHIBITOR CONTAINING SAME AS ACTIVE INGREDIENT - A novel compound having an excellent NFκB inhibitory effect is provided. Specifically disclosed is a compound represented by the following formula (1) or a salt thereof:
| 08-18-2011 |
| 20110172429 | STAT3 INHIBITOR CONTAINING QUINOLINECARBOXAMIDE DERIVATIVE AS ACTIVE INGREDIENT - The present invention provides a STATS inhibitor containing as an active ingredient, a quinolinecarboxamide derivative represented by the formula (I) (in the formula, W represents a bond or an alkylene chain; X represents O, S, or NR | 07-14-2011 |
| 20110071224 | NOVEL GAMMA-SECRETASE INHIBITOR - It is intended to provide a novel compound that has an excellent γ-secretase inhibitory effect and specifically inhibits Aβ production. | 03-24-2011 |
| 20110003842 | MARKER FOR DETERMINATION OF SENSITIVITY TO ANTI-CANCER AGENT - Provided are a marker for determining sensitivity to an anticancer agent capable of distinguishing a therapeutic response of an individual patient and a novel means for a cancer therapy using the marker. The marker for determining sensitivity to an anticancer agent contains a substance in a metabolic pathway in which L-phenylalanine and/or N,N-dimethyl glycine are/is involved. | 01-06-2011 |
| 20100323034 | METHOD FOR DETERMINATION OF SENSITIVITY TO ANTI-CANCER AGENT - Provided are an marker for determining sensitivity to an anticancer agent capable of distinguishing a therapeutic response of an individual patient and a novel means for a cancer therapy using the marker. The marker for determining sensitivity to an anticancer agent contains a calcium-binding protein S100A7, S100A8, or S100A10. | 12-23-2010 |
| 20100291242 | ANTAGONIST AGAINST TOLERANCE TO ANTICANCER DRUGS - An ABC transporter protein expression inhibitor comprising, as the active ingredient(s), 0.001 to 100 nM of one or more members selected from among steroid hormones, compounds having a female hormone function, analogous compounds thereof and antagonistic inhibitors therefor; an anticancer composition containing this ABC transporter protein expression inhibitor and an anticancer drug; and cells useful in the development of an anticancer drug. The present invention provides a drug which inhibits the expression of an ABC transporter to thereby overcome resistance to anticancer drugs; cancer cells useful in screening such drugs; and an anticancer drug efficacious even against such a cancer as having acquired resistance to anticancer drugs. | 11-18-2010 |
| 20100291049 | ANTI-WRINKLE AGENT - The invention provides an anti-wrinkle agent which has an excellent effect of inhibiting the formation of wrinkles and excellent safeness. | 11-18-2010 |
| 20100249209 | GENE INVOLVED IN IMMORTALIZATION OF HUMAN CANCER CELL AND USE THEREOF - The present invention provides a gene related to cancer cell immortalization (an immortalization determining gene) and a process that is useful for selective cancer treatment targeting a cancer cell having the gene. The present invention determines an immortalized cancer cell using a polynucleotide having a base sequence of at least 15 bases that specifically hybridizes with a continuous base sequence of at least 15 bases within any one of abase sequences represented by SEQ ID Nos. 1 to 13. In the foregoing process, the polynucleotide is used as a primer or probe for detecting an immortalization determining gene that exhibits high expression specifically in an immortalized cancer cell. | 09-30-2010 |
| 20100249089 | ABCG2 INHIBITOR - The present invention relates to a breast cancer resistance protein (BCRP/ABCG2) inhibitor. | 09-30-2010 |
| 20100166271 | Method for Counting Colonies - Problem to be Solved There is provided a colony counting method capable of obtaining highly reliable and stable colony count values with easy and simple means by eliminating the variation in colony count due to image capturing conditions when the number of colonies is counted by performing data processing on an image obtained by image capturing means performing image capturing on a petri dish. | 07-01-2010 |
| 20100144551 | CYTOKINE PRODUCTION REGULATOR GENE AND USE THEREOF - The invention provides a gene encoding a protein selected from among the following proteins (a) to (c): (a) a protein having any of the amino acid sequences of SEQ ID NOs: 2, 4, 6, 8, 10, 12, 14, 16, 82, 84, 86, 88, 90, 92, 94, 96, 98, 100, 102, 104, 106, and 108; (b) a protein which has an amino acid sequence equivalent to any of the amino acid sequences of (a), except that one to several amino acid residues are deleted, substituted, or added, and which exhibits cytokine production regulatory activity; and (c) a protein which has an amino acid sequence having 90% or higher identity to any of the amino acid sequences of (a), and which exhibits cytokine production regulatory activity, as well as a gene useful for regulating cytokine production and use of the gene. | 06-10-2010 |
| 20100130525 | AQUEOUS SOLUTION PREPARATION CONTAINING CAMPTOTHECIN COMPOUNDS - An object of the invention is to provide a camptothecin compounds-containing aqueous pharmaceutical preparation which can be produced without heating and in which camptothecin compounds are dissolved in a stable state. The invention provides a camptothecin compound-containing aqueous pharmaceutical preparation, containing the following ingredients (a) to (c):
| 05-27-2010 |
| 20100015281 | FERMENTED FOOD CONTAINING BIFIDOBACTERIUM BACTERIA AND METHOD FOR PRODUCING THE SAME - Provided is a fermented food containing an extract of at least one plant material selected from the group consisting of turmeric, | 01-21-2010 |
| 20090253656 | BCRP/ABCG2 INHIBITOR - The present invention is directed to a breast cancer resistance protein (BCRP/ABCG2) inhibitor. | 10-08-2009 |
| 20090253643 | EQUOL LEVEL REGULATOR - An object of the invention is to provide a medical drug, a food and drink having a role in regulating the concentration of equal in vivo and being capable of taking for a long time with high safety and provide a selective medium for a microorganism having conversion ability to equal and a method of detecting the same. Provided are an equal concentration-raising or reducing agent containing a carbohydrate as an active ingredient; use of a carbohydrate for producing the equal concentration-raising or reducing agent; a method of raising or reducing the concentration of equal by administrating a carbohydrate in an effective dose; a selective medium containing a carbohydrate for a microorganism having conversion ability to equal; and a method of detecting a microorganism having conversion ability to equal by use of the selective medium. | 10-08-2009 |
| 20090252709 | NOVEL BACTERIUM BELONGING TO THE GENUS BIFIDOBACTERIUM AND UTILIZATION OF THE SAME - It is intended to provide | 10-08-2009 |
| 20090212060 | Packaging Container - It is to provide a packaging container comprising: a synthetic resin container body having a flange part at a periphery of an opening at an upper end thereof; and a container cap having a top board part and a skirt part provided such that it is suspended from a-periphery of the top board part, and wherein the top board part is heat-sealed onto an upper surface of the flange part of the container body; wherein the packaging container has a first cutout part at an upper end of an outer edge of the flange part. By providing a first cutout part, a packaging container possible to achieve sealing with the container cap stably, and to open the sealing easily and surely as well can be provided, by suppressing the effect of a molten resin on a folded corner part of the skirt of the container cap when the container body is heat-sealed with the container cap. | 08-27-2009 |
| 20090170185 | CHOLESTEROL ABSORPTION INHIBITOR - To provide a bacterium belonging to the genus | 07-02-2009 |
| 20090170078 | METHOD OF QUANTITATIVELY ANALYSING MICROORGANISM TARGETING RRNA - An object of the present invention is to provide a method of quantitating or detecting a microorganism, capable of detecting a live microorganism at high sensitivity and more precisely. A method of quantitating a microorganism of interest, using as an index the amount of rRNA of the microorganism of interest is provided. | 07-02-2009 |
| 20090087500 | GUAVA LEAF EXTRACT POWDER AND METHOD FOR PRODUCTION THEREOF - To provide a guava leaf extract powder which exhibits less deterioration in quality and functions after storage of the solution thereof for a long period of time. | 04-02-2009 |
| 20090074897 | AGENT FOR ELEVATING ADIPONECTIN CONCENTRATION - To provide a highly safe medicament or food or beverage which exhibits the effect of elevating blood adiponectin level, and which allows intake thereof over a long period of time. The invention provides an adiponectin level elevating agent including guava leaf extract as an active ingredient. | 03-19-2009 |
| 20090023927 | Process for producing tricyclic ketone - In order to efficiently supply CPT, which is a starting compound of irinotecan hydrochloride and a variety of camptothecin derivatives, by a practical total synthesis, the invention provides a means of efficiently preparing a tricyclic ketone that corresponds to a CDE ring moiety of a camptothecin (CPT) skeleton. | 01-22-2009 |
| 20080292751 | Lactic Acid Bacteria Fermented Substance and Fermented Milk Food Product Containing the Same - An object of the invention is to provide a lactic acid bacteria fermentation product, which has been obtained by culturing lactic acid bacteria on a medium containing an extract of at least one food material selected from the group consisting of rice bran, persimmon leaves, | 11-27-2008 |
| 20080289986 | Overwrap Packed Body, Perforated Line Forming Method and Perforated Line Forming Apparatus - An overwrap packed body is obtained by heating and shrinking a wrapping material in a condition that five drink products collectively wrapped by the wrapping material. Three perforated lines passing through gap portions between the adjacent drink products are formed on the wrapping material at an interval of 2 mm in parallel. When the three perforated line portions are pushed with fingers in the gap portion between the adjacent drink products, the wrapping material torn from the pushed portion in a vertical direction. Thus, the packed drink products DG can be easily taken out one by one. | 11-27-2008 |
| 20080287374 | BREAST CANCER-RESISTANT PROTEIN INHIBITOR - The invention provides a cancer cell useful in screening BCRP-inhibitors, and a BCRP-inhibitor. | 11-20-2008 |
| 20080260709 | CHOLESTEROL-LOWERING AGENTS, SECONDARY BILE ACID PRODUCTION INHIBITORS AND FOODS AND DRINKS - Secondary bile acid production inhibitors and cholesterol-lowering agents containing a yeast as the active ingredient. | 10-23-2008 |
| 20080249036 | Antagonist Against Tolerance to Anticancer Drugs - An ABC transporter protein expression inhibitor comprising, as the active ingredient(s), 0.001 to 100 nM of one or more members selected from among steroid hormones, compounds having a female hormone function, analogous compounds thereof and antagonistic inhibitors therefor; an anticancer composition containing this ABC transporter protein expression inhibitor and an anticancer drug; and cells useful in the development of an anticancer drug. The present invention provides a drug which inhibits the expression of an ABC transporter to thereby overcome resistance to anticancer drugs; cancer cells useful in screening such drugs; and an anticancer drug efficacious even against such a cancer as having acquired resistance to anticancer drugs. | 10-09-2008 |
| 20080242691 | Aqueous Solution Preparation Containing Camptothecins - An aqueous solution preparation containing camptothecins which does not require heating in its production, and wherein camptothecins have been solubilized in a stable manner is provided. | 10-02-2008 |
| 20080227165 | Process for producing conjugated fatty acid and food/drink produced by the process - A conjugated fatty acid such as the cis-9, trans-11 isomer of conjugated linoleic acid having high bioactivities is selectively and efficiently produced by conjugating an unsaturated fatty acid having at least two double bonds with the use of viral cells, dead cells or a cell extract of at least one bacterium selected from the group consisting of | 09-18-2008 |
