JUSTUS-LIEBIG-UNIVERSITAT GIESSEN Patent applications |
Patent application number | Title | Published |
20140106379 | Immunological Test for Detecting Autoantibodies Against Testicular Antigens - The present invention discloses an immunological test for the detection and specific determination of autoantibodies against testicular antigens which are associated with inflammation-related fertility disorders of male mammals in a biological sample of a male mammal, in particular the detection of testicular ER-60 autoantibodies and/or transferrin autoantibodies. | 04-17-2014 |
20130267731 | Tripodal Bisphosphonate Derivatives - The present invention describes tripodal bisphosphonate derivatives with a flexible basic framework for the functionalisation of surfaces, and methods for their production and use. The central atom of the flexible framework is hereby a tertiary aliphatic carbon atom. A fourth remaining position of the flexible framework is suitable to be optionally functionalised by so-called click reactions, for example with biomolecules, polyethylene glycol or active agents. | 10-10-2013 |
20130266645 | DERIVATIVES OF STEROID BENZYLAMINES, HAVING AN ANTIPARASITIC ANTIBACTERIAL, ANTIMYCOTIC AND/OR ANTIVIRAL ACTION - The present invention relates to compounds derived from steroids of the general formula (I) | 10-10-2013 |
20130245270 | Synthesis of Trivalent Flexible Frameworks with Ligands Comprising Catechol Units for Functionalizing Surfaces - The present invention describes tripodal catechol derivatives with a flexible basic framework for the functionalisation of surfaces, and methods for their production and use. The central atom of the flexible framework is hereby a tertiary aliphatic carbon atom. The remaining fourth bridgehead position is easily suitable to be further functionalised via so-called click reactions, e.g. with biomolecules, dyes, radiomarkers, polyethylene glycol or active agents. | 09-19-2013 |
20130220178 | Re-Dispersible Metal Oxide Nanoparticles and Method of Making Same - The current invention relates to a method of making metal oxide nanoparticles comprising the reaction of—at least one metal oxide precursor (P) containing at least one metal (M) with—at least one monofunctional alcohol (A) wherein the hydroxy group is bound to a secondary, tertiary or alpha-unsaturated carbon atom—in the presence of at least one aliphatic compound (F) according to the formula Y | 08-29-2013 |
20130217916 | Synthesis of Tripodal Bisphosphonate Derivatives Having an Adamantyl Basic Framework for Functionalizing Surfaces - The present invention describes tripodal catechol derivatives with an adamantyl basic framework for the functionalisation of surfaces, and methods for their production and use. A fourth remaining position of the adamantane skeleton is suitable to be optionally functionalised by so-called click reactions, for example with biomolecules, polyethylene glycol or active agents. | 08-22-2013 |
20130165625 | PEPTIDES INCORPORATING 3-AMINOADAMANTANE CARBOXYLIC ACIDS ENHANCE SYNAPTIC PLASTICITY AND ACT AS NEUROGENIC AGENTS - The disclosed invention relates to peptides incorporating 3-aminoadamantane-1-carboxylic acids. These peptides are disclosed as surprisingly possessing neurogenic and neurotrophic properties. These pharmacological activities can advantageously be utilized for restoring or maintaining neuronal function in the CNS. In particular, the compounds can be used for treatment and prophylaxis of neurodegenerative diseases, e. g., Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, as well as in post-acute traumatic brain injury, or cerebral ischemia. | 06-27-2013 |
20130149535 | BIODEGRADABLE NANO-, MESO-, AND MICRO-POLYMER PARTICLES FOR MAINTAINING A LOW SURFACE TENSION IN THE LUNG AND FOR PROTECTING THE PULMONARY SURFACTANT - The present invention provides nano-, meso- and micro-polymer particles which are able to bind pathogenic proteins penetrating into the lining layer of the lung. Known pathogenic proteins in the pulmonary lining layer are negatively charged. These proteins damage the pulmonary surfactant system which is essential to maintain a low surface tension in the lung and thus a functional respiration. Polymer particles of this invention have a diameter between 20 nm and 10 μm, are water-insoluble, have a positive surface charge and a low surface hydrophobicity. The isoelectric point of said particles is greater than 5 to that said particles are present in the lining layer of the lung as positively charged particles, and at the same time higher than the isoelectric point of the pathogenic protein to be bound. Polymer particles of this invention can for example be prepared using the precipitation or emulsion method. Polymer particles of this invention can be utilized for maintaining a low surface tension in the lung and for protecting the pulmonary surfactant. | 06-13-2013 |
20130095108 | FACTOR XII INHIBITORS FOR TREATING INTERSTITIAL LUNG DISEASE - The present invention provides methods for treating interstitial lung diseases, comprising administering to an individual an effective amount of an inhibitor of coagulation factor XII. The invention further provides uses and pharmaceutical kits for that treatment. | 04-18-2013 |
20120270942 | Spreading Active Agricultural Agents - Disclosed herein is a device for the application of agricultural active agents, wherein the device is suitable to be brought to the site of action in a manner temporally and spatially separated from the production process, and comprises a dispenser and non-water-soluble nanofibers and/or mesofibers charged with agricultural active agents. The polymers from which the nanofibers and/or mesofibers are made are preferably biodegradable. The agricultural active agents are selected from fungicides, herbicides, batericides, plant growth regulators and plant nutrients. These are preferably pheromones, kairomones and signaling substances. Furthermore, a method for the production of this device is disclosed, wherein the nanofibers and/or mesofibers charged with active agents are produced via electrospinning. The device is suitable to be used to bring agricultural active agents to the site of action in a manner temporally and spatially separated from the production of this device. The application is suitable to be carried out mechanically or automatically. This is preferably agricultural land used for fruit growing, viticulture, gardening or a commercial row crop. The device according to the present invention is particularly suitable to be used for the regulation of arthropods. | 10-25-2012 |
20120148493 | Composite Materials Loaded with Therapeutic and Diagnostic Agents Comprising Polymer Nanoparticles and Polymer Fibers - The invention relates to composite materials comprising polymer nanofibers and polymer nanoparticles, wherein at least one of the two polymer materials is loaded with a substance selected from therapeutic and diagnostic agents. Fibers and nanoparticles can comprise identical or different polymers; the polymer materials are, however, biocompatible in every case. Therapeutic and diagnostic agents can be hydrophilic or lipophilic and the two polymer materials likewise. The at least one polymer material and the substance with which said material is loaded are either both hydrophilic or both lipophilic. The polymer nanoparticles of the composite materials have a diameter of 10 nm to 600 nm. The polymer fibers have diameters of 10 nm to 50 μm and lengths of 1 μm to several meters. The invention further relates to a method for producing said composite materials. Polymer nanoparticles can be produced in different ways, such as through controlled precipitation of a polymer solution that optionally comprises a loading substance. The nanoparticles are then mixed with another polymer and a loading substance as applicable, depending on whether particles, fibers or both are to be loaded with substance. The processing of this solution into composites comprising polymer fibers polymer nanoparticles can occur by means of electrospinning, melt spinning, extruding or template process. Composite materials according to the invention are suitable for the production of pharmaceuticals that release therapeutically or diagnostically effective substances slowly and in a controlled manner. | 06-14-2012 |
20120129800 | Agent For Preventing And Treating Pityriasis Versicolor - The present invention concerns an agent for prevention and treatment of pityriasis. | 05-24-2012 |
20110300383 | NANOSCALED POLYMER FIBERS - The invention relates to supports consisting of nanoscalar polymer fibres, polymer tubes or hollow fibres for the application and targeted and/or delayed release of ingredients, in particular, agricultural active ingredients. The invention also relates to a method and a device for the production of supports of this type in a charged or empty state. The method and device use electrospinning technology. | 12-08-2011 |
20110300251 | DEVICE FOR THE EXECUTION OF THE OUTPUT OF NANOSCALED POLYMER FIBERS - Carriers for the production and targeted and/or delayed release, particularly of agricultural active substances, as well as a method for the output and a device for the production of such carriers in a loaded or unloaded state are proposed. The method and the device use the technology of electrospinning. | 12-08-2011 |
20110293846 | METHOD FOR COATING TARGET SURFACES IN THE FORM OF DIELECTRIC SUBSTANCES OR FERROELECTRIC CRYSTALS - The invention relates to supports consisting of nanoscalar polymer fibres, polymer tubes or hollow fibres for the application and targeted and/or delayed release of ingredients, in particular, agricultural active ingredients. The invention also relates to a method and a device for the production of supports of this type in a charged or empty state. The method and device use electrospinning technology. | 12-01-2011 |
20110269157 | Immunological Test For Detecting Autoantibodies Against Testicular Antigens - The present invention discloses an immunological test for the detection and specific determination of autoantibodies against testicular antigens which are associated with inflammation-related fertility disorders of male mammals in a biological sample of a male mammal, in particular the detection of testicular ER-60 autoantibodies and/or transferrin autoantibodies. The immunological test is utilized to detect the presence of immunologically-caused and infection-related infertility in male mammals, particularly in humans. | 11-03-2011 |
20110124912 | MONOETHERIFIED DIOLS OF DIAMONDOIDS - The invention at hand describes functionalized diols of diamondoids, in which one of the two hydroxy groups is masked by a protective group, as well as methods for producing these functionalized diols. The protective group is a group —CHR | 05-26-2011 |