| JULIUS MAXIMILIANS-UNIVERSITÄT WÜRZBURG Patent applications |
| Patent application number | Title | Published |
|---|
| 20120100151 | Antibodies or Fragments Thereof Directed Against a Staphylococcus Aureus Epitope of ISAA or ISAB - The invention concerns antibodies or fragments thereof that are directed against a | 04-26-2012 |
| 20110157594 | OPTICAL ASSEMBLY, APPARATUS AND METHOD FOR COHERENT TWO-OR-MORE-DIMENSIONAL OPTICAL SPECTROSCOPY - An optical assembly for use in coherent two- or more-dimensional optical spectroscopy includes a beam splitter that splits a base light pulse into first, second, third and fourth light pulse and a delay element that varies the arrival times of the first to fourth light pulses at a sample location with respect to each other. The beam splitter includes a cross-grating a first reflector arranged to receive the first to fourth light pulses emerging from the cross-grating and to reflect the same in parallel to each other, a second reflector arranged to receive the first to fourth light pulses from the delay element and to focus the same at the sample location, wherein the delay element is arranged between first and second reflectors. Also shown is an apparatus including such optical assembly and a method for carrying out two- or more-dimensional optical spectroscopy using the assembly. | 06-30-2011 |
| 20110141467 | APPARATUS AND METHOD FOR COHERENT MULTI-DIMENSIONAL OPTICAL SPECTROSCOPY - An apparatus and a method for coherent multi-dimensional optical spectroscopy employs a beam splitter for splitting a base light pulse into at least first to fourth light pulses, three of which are suitable for interaction with a sample, lens system focuses the first to fourth light pulses at a sample site, and an optical delay varies the arrival times of the first to fourth light pulses at the sample. A detector detects an interference signal. The beam splitter is a non-diffractive optical element. The light pulses, at least along part of their light paths, are guided pairwisely such that changes in the optical path length due to vibration of the beam splitter or due to the delay element are identical for each pair of pulses, where the pulse pairs compensate for any change in the interference signal due to a change of the arrival times of the pair of pulses. | 06-16-2011 |
| 20110071211 | MicroRNA (miRNA) And Downstream Targets For Diagnostic And Therapeutic Purposes - The present invention relates to a promoter region of a microRNA, the use of a microRNA, in particular miR-21, and related elements for the diagnosis and for the manufacture of a medicament for the treatment and/or prevention of fibrosis and/or fibrosis related diseases. Additionally, the invention concerns antisense oligonucleotides against targets of miR-21. A cell deficient for miR-21, the promoter region and targets of miR-21 and a knock-out organism thereof are also encompassed. Finally, the invention is directed to a method for diagnosing fibrosis and/or fibrosis related diseases and to a method for screening a pharmaceutically active compound for the treatment of fibrosis and/or fibrosis related diseases. The present invention further relates to compositions for use in the treatment, amelioration, and/or prevention of fibrosis. In certain embodiments, the compositions modulate the activity of a miRNA for the treatment, amelioration, and/or prevention of fibrosis. In certain embodiments, the compositions inhibit the activity of miR-21 for the treatment, amelioration, and/or prevention of fibrosis. | 03-24-2011 |
| 20100010073 | MICRORNA (MIRNA) FOR THE DIAGNOSIS AND TREATMENT OF HEART DISEASES - The invention relates to microRNAs (miRNAs) for the diagnosis, prophylaxis and/or treatment of heart diseases. It relates in particular to SEQ ID No: 1 to SEQ ID No: 29 for the diagnosis, prophylaxis and/or treatment of heart diseases. In addition, the invention relates to the use of these sequences to produce a medicament for heart diseases and for the diagnosis thereof. Also encompassed are a method for the diagnosis of a heart disease, a kit and an expression vector comprising these sequences, a cell which contains the expression vector, and also a method for modulating a heart disease and a method for screening a pharmaceutically active compound for the treatment and/or prophylaxis of a heart disease. | 01-14-2010 |
