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Johnson & Johnson Pharmaceutical Research & Development, LLC

Johnson & Johnson Pharmaceutical Research & Development, LLC Patent applications
Patent application numberTitlePublished
20100189654ANIMAL MODEL FOR EVALUATING VASOMOTOR RESPONSE IN VIVO - A method for evaluating the effect of a compound on vasomotor response in vivo comprises the steps of administering said compound to a rabbit and measuring the diameter of the vessel lumen of a central ear artery of said rabbit in comparison with the baseline diameter of the vessel lumen of said central ear artery of said rabbit, said baseline diameter being measured prior to the administration of said compound.07-29-2010
20100136594HIGH-THROUGHPUT ASSAY FOR EVALUATING DIPEPTIDYL PEPTIDASE I ACTIVITY - A method of screening a compound which modulates dipeptidyl peptidase I (DPPI) activities comprises the steps of adding a peptide substrate of DPPI to a reaction mixture which comprises DPPI and a compound, wherein the peptide substrate of DPPI has at least 3 amino acids and binds to a binding site of DPPI in addition to the S06-03-2010