| JIANGSU UNIVERSITY Patent applications |
| Patent application number | Title | Published |
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| 20120060648 | METHOD FOR PRODUCING MULTIPHASE PARTICLE-REINFORCED METAL MATRIX COMPOSITES - A method for producing multiphase particle-reinforced metal matrix composites is provided. The method is characterized by the combination of an in-situ reaction process under an external electromagnetic field and an in-situ crystallization process under an external electromagnetic field. A traveling wave magnetic field or a rotating magnetic field is employed during the in-situ reaction process, and a rotating magnetic field or a high frequency magnetic field is employed during the in-situ crystallization process. Said method can obtain homogeneous, gradient enhanced or surface reinforced composite materials. | 03-15-2012 |
| 20120029064 | FORMULATION OF SILIBININ WITH HIGH EFFICACY AND PROLONGED ACTION AND THE PREPARATION METHOD THEREOF - A high-efficacy, long-acting formulation of silibinin, comprising silibinin solid dispersion, silibinin-loaded silica nanoparticles, slow-release matrix material and release enhancer, wherein the mass ratio of these components is silibinin solid dispersion:silibinin-loaded silica nanoparticles:slow-release matrix material:release enhancer=1:0.5˜1.25:0.1˜0.3:0.1˜0.3; the drug loading rate of the said silibinin-loaded silica nanoparticles is 51.29˜51.77%; the said silibinin solid dispersion contains povidone K30, soybean lecithin, acrylic resin IV, wherein the mass ratio between silibinin and other medical accessories is silibinin:povidone K30:soybean lecithin:acrylic resin IV=1:1˜3:0.3˜0.8:0.2˜0.5. Compared with the existing formulations, the half life of the high-efficacy, long-acting formulation of silibinin disclosed in this invention is 14.8 times longer while the mean residence time (MRT) of which is 4.52 times longer; when tested in vivo in Beagle dogs, this new formulation of silibinin presents a smoother concentration-time curve and reaches the continuous release for 72 hours. This invention discloses its preparation method. | 02-02-2012 |
| 20110250269 | HIGHLY EFFICIENT AND LONG-ACTING SLOW-RELEASE FORMULATION OF POORLY SOLUBLE DRUGS AND PREPARATION METHOD THEREOF - A high-efficacy, long-acting, slow-release formulation of the poorly soluble drug, comprising solid dispersion of the poorly soluble drug, silica nanoparticles loaded with the poorly soluble drug, matrix material, and release enhancer, wherein the mass ratio of these components is solid dispersion of the poorly soluble drug: silica nanoparticles loaded with the poorly soluble drug: matrix material: release enhancer=1: 0.5˜1.25: 0.1˜0.3: 0.1˜0.3; the said solid dispersion of the poorly soluble drug contains povidone K30, soybean lecithin, and acrylic resin IV, wherein the mass ratio of the drug and the accessory materials is poorly soluble drug: povidone K30: soybean lecithin: acrylic resin IV=1: 1-3: 0.3˜0.8: 0.2˜0.5. Compared with the existing formulations, the in vivo half life of the high-efficacy, long-acting formulation of the poorly soluble drug disclosed in this invention is 2.3˜14.8 times longer while the mean residence time (MRT) of which is 7.94˜4.52 times longer; when tested in vivo in Beagle dogs, this new formulation of the poorly soluble drug presents a smoother concentration-time curve and reaches a continuous release for 72 hours. This invention discloses its preparation method. | 10-13-2011 |
| 20110247778 | METHOD OF SYNTHESIZING METAL -BASED COMPOSITE MATERIAL BY MELT REACTION IN COUPLING MAGNETIC FIELD AND ULTRASONIC FIELD - A method of synthesizing metal matrix composite material by melt reaction in coupling magnetic field and ultrasonic field comprises: adjusting metal-base melt to the onset reaction temperature after refining, then adding reactants which generate reinforced particles by in-situ synthesis reaction with melt, keeping the reacted melt stand until it is cooled to casting temperature after the reaction, and then casting. Magnetic field and high-energy ultrasonic field are exerted simultaneously during the reaction. The magnetic field can be high-power pulse magnetic filed, high-frequency oscillating magnetic field or low-frequency alternating magnetic field. The metal matrix composite material produced by the above-mentioned method exhibits that reinforced particles are much finer, more uniformly distributed, and fit with metal matrix better. | 10-13-2011 |
| 20110247263 | CONTROL METHOD AND APPARATUS OF WIND MACHINE FOR PLANT FROST PROTECTION - This invention relates to control method and apparatus of wind machine for plant frost protection, and belongs to the domain of agro-meteorological disaster monitoring and control. Existing wind machines for plant frost protection only rely on critical damage temperature or wind speed as a condition to start. If there is no thermal inversion, operation of the wind machine will aggravate freezing injury to plants. If the strength of thermal inversion is weak, the effect will be minimal The feature of this invention is that when temperature at the plant canopy is lower than the critical damage temperature of a certain plant and temperature difference between the top and bottom of the thermal inversion layers exceeds set threshold, wind machine will start automatically. Otherwise it will remain off. The control apparatus mainly consists of sensor | 10-13-2011 |
| 20110201680 | FORMULATION OF SILYMARIN WITH HIGH EFFICACY AND PROLONGED ACTION AND THE PREPARATION METHOD THEREOF - A high-efficacy, long-acting formulation of silymarin, comprising silymarin solid dispersion, silymarin-loaded silica nanoparticles, slow-release matrix material and release enhancer, wherein the mass ratio of these components is silymarin solid dispersion:silymarin-loaded silica nanoparticles:slow-release matrix material:release enhancer=1:0.5˜1.25:0.1˜0.3:0.1˜0.3; the drug loading rate of the said silymarin-loaded silica nanoparticles is 51.95%-52.87%; the said silymarin solid dispersion contains povidone K30, soybean lecithin and acrylic resin IV, and the mass ratio between silymarin and other medical accessories in silymarin solid dispersion is silymarin:povidone K30:soybean lecithin:acrylic resin IV=1:1˜3:0.3˜0.8:0.2˜0.5. Compared with the existing formulations, the half life of the high-efficacy, long-acting formulation of silymarin disclosed in this invention is 2.3 times longer while the mean residence time (MRT) of which is 9.94 times longer; when tested in vivo in Beagle dogs, this new formulation of silymarin presents a smoother concentration-time curve and reaches a continuous release for 72 hours. This invention discloses its preparation method. | 08-18-2011 |
