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JAPANESE FOUNDATION FOR CANCER RESEARCH

Tokyo, JP

JAPANESE FOUNDATION FOR CANCER RESEARCH Patent applications
Patent application numberTitlePublished
20120115146METHOD OF ANALYZING GENETICALLY ABNORMAL CELLS - The present invention relates to a method for analyzing genetically abnormal cells including (a) preparing a cell sample containing eukaryotic cells, (b) conducting an antigen-antibody reaction to cells contained in the cell sample using antibodies which specifically bind to a molecule existing on the cell surface of eukaryotic cells after (a), (c) subjecting the cells contained in the cell sample to a permeation treatment after (b), (d) subjecting the cells contained in the cell sample to an immobilization treatment after (b), (e) conducting FISH to the cells contained in the cell sample using nucleic acid probes after (d), (f) analyzing fluorescence signals from the nucleic acid probes in the cells contained in the cell sample using a three-dimensional image analysis method after (e), and (g) determining whether the cells contained in the cell sample are genetically abnormal cells or not based on the results of (b) and (f).05-10-2012
20120095331INFORMATION PROCESSING APPARATUS AND INFORMATION PROCESSING METHOD AND PROGRAM FOR THEM - Disclosed herein is an information processing apparatus including: a lesion progress rate recognition section configured to perform prescribed image recognition processing on a plurality of entered medical images, thereby recognizing the lesion progress rate that represents the rate of progress of the disease-induced change in living body; and a presentation control section configured to cause a presentation section to present the medical images according to the lesion progress rate which has been recognized by the lesion progress rate recognition section.04-19-2012
20120033064MICROSCOPE SYSTEM, SPECIMEN OBSERVING METHOD, AND COMPUTER-READABLE RECORDING MEDIUM - A microscope system includes a pigment amount calculating unit, a cell component identification processing unit, a target molecule expression portion extraction unit, a cell variant setting unit, a cell variant classification determining unit, and a display image generating unit. The pigment amount calculating unit calculates a pigment amount of a molecule target pigment for each pixel of a VS image. The cell component identification processing unit identifies a cell component based on the pigment amount. The target molecule expression portion extraction unit extracts expression portions of target molecules in the area of the cell component. The cell variant setting unit sets a cell variant including a combination of presence/absence of expressions of target molecules. The cell variant classification determining unit classifies a cell area in the VS image into a cell variant based on the combination of the expression portions of the target molecules included in the cell area.02-09-2012
20110243405IMAGE PROCESSING APPARATUS, IMAGE PROCESSING METHOD, AND PROGRAM - There is provided an image processing apparatus that analyzes a pathology image obtained by imaging an analysis object including a setting device for calculating an amount of a luminance difference characteristic as an amount of characteristic of each pixel of a pathology image, and for setting a cellular tissue region in the pathology image, based on the amount of the luminance difference characteristic, using a cellular tissue detector that has studied in advance. The cellular tissue detector may have studied in advance by statistical learning that uses an image corresponding to a cellular tissue.10-06-2011
20110212486Microscope System, Specimen Observation Method, and Computer Program Product - A microscope system includes an acquisition unit that obtains a specimen image acquired by capturing the specimen stained by an element identification dye that visualizes a predetermined cell constituent element and a molecule target dye that visualizes a predetermined target molecule by using a microscope; a dye amount unit that obtains dye amounts of the element identification dye and the molecule target dye that stain corresponding positions on the specimen for each pixel of the image; an element area identification unit that identifies an area of the cell constituent element based on the dye amount of the element identification dye; a condition setting unit that sets the presence or absence of the predetermined target molecule on the cell constituent element as a condition; and an extraction unit that extracts an area of a target portion that satisfies the condition based on the dye amount of the molecule target dye.09-01-2011
20100322502MEDICAL DIAGNOSIS SUPPORT DEVICE, IMAGE PROCESSING METHOD, IMAGE PROCESSING PROGRAM, AND VIRTUAL MICROSCOPE SYSTEM - The present invention provides a medical diagnosis support device, which is capable of acquiring information to support medical diagnosis for easily and precisely determining chromosome abnormality and/or gene amplification related to cancer or genetic disorder.12-23-2010
20100291242ANTAGONIST AGAINST TOLERANCE TO ANTICANCER DRUGS - An ABC transporter protein expression inhibitor comprising, as the active ingredient(s), 0.001 to 100 nM of one or more members selected from among steroid hormones, compounds having a female hormone function, analogous compounds thereof and antagonistic inhibitors therefor; an anticancer composition containing this ABC transporter protein expression inhibitor and an anticancer drug; and cells useful in the development of an anticancer drug. The present invention provides a drug which inhibits the expression of an ABC transporter to thereby overcome resistance to anticancer drugs; cancer cells useful in screening such drugs; and an anticancer drug efficacious even against such a cancer as having acquired resistance to anticancer drugs.11-18-2010
20090155241Prophylactic/therapeutic agent for cancer - A compound or its salt that inhibits the activity of a protein having the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID NO: 1; a compound or its salt that inhibits the expression of a gene for the protein; an antisense polynucleotide comprising a nucleotide sequence complementary or substantially complementary to the nucleotide sequence of a polynucleotide encoding the protein or a partial peptide thereof or a part of the nucleotide sequence; an antibody against the protein; etc. are useful as preventive/therapeutic agents for cancer, apoptosis promoters for cancer cells, or the like.06-18-2009
20080249036Antagonist Against Tolerance to Anticancer Drugs - An ABC transporter protein expression inhibitor comprising, as the active ingredient(s), 0.001 to 100 nM of one or more members selected from among steroid hormones, compounds having a female hormone function, analogous compounds thereof and antagonistic inhibitors therefor; an anticancer composition containing this ABC transporter protein expression inhibitor and an anticancer drug; and cells useful in the development of an anticancer drug. The present invention provides a drug which inhibits the expression of an ABC transporter to thereby overcome resistance to anticancer drugs; cancer cells useful in screening such drugs; and an anticancer drug efficacious even against such a cancer as having acquired resistance to anticancer drugs.10-09-2008

Patent applications by JAPANESE FOUNDATION FOR CANCER RESEARCH