| JAPAN TOBACCO INC. Patent applications |
| Patent application number | Title | Published |
|---|
| 20120121703 | TABLET CONTAINING FERRIC CITRATE - The present invention provides a new preparation which is a tablet containing (1) ferric citrate, (2) a polyvinyl alcohol-polyethylene glycol graft copolymer, and (3) a polyvinyl alcohol-acrylic acid-methyl methacrylate copolymer. | 05-17-2012 |
| 20120115827 | 3-AMINOBENZAMIDE COMPOUNDS AND VANILLOID RECEPTOR SUBTYPE 1 (VR1) INHIBITORS - The present invention relates to a novel 3-aminobenzamide, compound represented by the following formula which effectively inhibits vanilloid receptor subtype 1 (VR1) activity (wherein, for example, R | 05-10-2012 |
| 20120107273 | NEW PIPERAZINE COMPOUND AND USE THEREOF AS A HCV POLYMERASE INHIBITOR - The present invention relates to a compound represented by the following formula [I] | 05-03-2012 |
| 20120090799 | METHOD AND APPARATUS FOR MANUFACTURING CIGARETTE WRAPPING PAPER - Web to be formed into wrapping paper is applied with combustion inhibitor and then dried. Water is applied onto the entire surface of the opposite side to the combustion-inhibitor applied side of the web. The web applied with water is dried while pinched between drying and pressing rollers and stretched in a width direction. In this way, unwrinkled high-quality cigarette wrapping paper having a low ignition propensity can be stably and inexpensively manufactured. As the pressing roller, a heat-resistant rubber roller provided in its surface with a soft portion in a helical way is utilized. | 04-19-2012 |
| 20120070409 | TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR - The present invention relates to a tetracyclic fused heterocyclic compound represented by the following formula [I] | 03-22-2012 |
| 20120064543 | METHOD FOR DETECTING SUBSTANCE IN BIOLOGICAL SAMPLE - The present invention provides a method for detecting a substance in a biological sample, a carrier for using in the method, and a kit. The method of the present invention according to an embodiment includes:
| 03-15-2012 |
| 20120039874 | HUMAN MONOCLONAL ANTIBODY AGAINST A COSTIMULATORY SIGNAL TRANSDUCTION MOLECULE AILIM AND PHARMACEUTICAL USE THEREOF - Immunization of human antibody-producing transgenic mice, which have been created using genetic engineering techniques, with AILIM molecule as an antigen resulted in various human monoclonal antibodies capable of binding to AILIM and capable of controlling a variety of biological reactions (for example, cell proliferation, cytokine production, immune cytolysis, cell death, induction of ADCC, etc.) associated with AILIM-mediated costimulatory signal (secondary signal) transduction. Furthermore, it has been revealed that the human monoclonal antibody is effective to treat and prevent various diseases associated with AILIM-mediated costimulatory signal transduction, being capable of inhibiting the onset and/or advancement of the diseases. | 02-16-2012 |
| 20120020920 | 5-5-MEMBERED FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR - The present invention relates to a fused ring compound represented by the following formula [I] | 01-26-2012 |
| 20120003231 | CELL SURFACE MOLECULE MEDIATING CELL ADHESION AND SIGNAL TRANSMISSION - Novel cell surface molecules recognized by monoclonal antibodies against a cell surface molecule of lymphocytic cells that play an important role in autoimmune diseases and allergic diseases have been isolated, identified, and analyzed for their functions. The cell surface molecules are expressed specifically in thymocytes, lymphocytes activated by ConA-stimulation, and peripheral blood lymphocytes, and induce cell adhesion. Antibodies against the cell surface molecules significantly ameliorate pathological conditions of autoimmune diseases and allergic diseases. | 01-05-2012 |
| 20110306599 | INDOLE COMPOUNDS AND PHARMACEUTICAL USE THEREOF - Provided is an agent for the treatment or prophylaxis of inflammatory diseases, allergic diseases, autoimmune diseases, transplant rejection or the like. | 12-15-2011 |
| 20110277181 | DROUGHT TOLERANT PLANTS AND RELATED CONSTRUCTS AND METHODS INVOLVING GENES ENCODING DTP21 POLYPEPTIDES - Isolated polynucleotides and polypeptides and recombinant DNA constructs useful for conferring drought tolerance, compositions (such as plants or seeds) comprising these recombinant DNA constructs, and methods utilizing these recombinant DNA constructs. The recombinant DNA construct comprises a polynucleotide operably linked to a promoter that is functional in a plant, wherein said polynucleotide encodes a DTP21 polypeptide. | 11-10-2011 |
| 20110245223 | HETEROCYCLIC COMPOUNDS - The present invention provides a compound represented by the following formula [1′] or a salt thereof: | 10-06-2011 |
| 20110212952 | 3,4-DIHYDROBENZOXAZINE COMPOUNDS AND INHIBITORS OF VANILLOID RECEPTOR SUBTYPE 1 (VRI) ACTIVITY - A 3,4-dihydrobenzoxazine compound of the present invention is represented by the following formula [1] (wherein X is a nitrogen atom or CR | 09-01-2011 |
| 20110192408 | NON-COMBUSTION FLAVOR INHALATION ARTICLE - A non-combustion flavor inhalation article includes a heating device including a heater to be heated to a temperature between 80 and 140° C., and a roll including a tobacco sheet to be disposed in contact with the heater. | 08-11-2011 |
| 20110189210 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION - The present invention aims at provision of a method for inhibiting remnant lipoprotein production and a remnant lipoprotein production inhibitor, which includes administering a compound having a CETP inhibitory activity to an administration subject. The remnant lipoprotein production inhibitor of the present invention contains a compound having a CETP inhibitory activity as an active ingredient. | 08-04-2011 |
| 20110178944 | SYSTEM FOR CALCULATING THE NUMBER OF DELIVERY ROUTES, AND METHOD FOR CALCULATING THE NUMBER OF DELIVERY ROUTES - The necessary number of delivery routes is accurately calculated corresponding to properties of an area. A system | 07-21-2011 |
| 20110136778 | NITROGEN-CONTAINING SPIROCYCLIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF - A compound of the following general formula [I]: | 06-09-2011 |
| 20110107469 | NOVEL PROTEIN, A GENE ENCODING THEREFOR AND A METHOD OF USING THE SAME - An object of the present invention is to search and identify novel antifungal proteins capable of inhibiting the growth of plant pathogenic microorganisms including | 05-05-2011 |
| 20110077267 | TRIAZOLOPYRIDINE COMPOUND, AND ACTION THEREOF AS PROLYL HYDROXYLASE INHIBITOR OR ERYTHROPOIETIN PRODUCTION-INDUCING AGENT - The present invention provides a triazolopyridine compound having a prolyl hydroxylase inhibitory action and an erythropoietin production-inducing ability. The present invention relates to a compound represented by the following formula [I]: | 03-31-2011 |
| 20110053250 | ENRICHMENT METHOD OF VIRUS - The present invention provides a novel method that can increase readily a virus or viral vector concentration in a solution having a low concentration and a kit for performing the method. Conventional methods require complicated operations, expensive equipment, or highly trained experts for efficiently concentrating viruses from low-concentration virus solutions. The method of the present invention can concentrate viral vectors readily while maintaining infection abilities of the viral vectors, and thus it can be used as a safe and simple technique for concentrating a vector useful in the field of a genetic therapy or a vaccine therapy using a viral vector. | 03-03-2011 |
| 20110053145 | QUANTITATION METHOD OF VIRUS - The present invention relates to a method of quantitatively determining the number of human herpesvirus (HHV) collected from a body fluid and a kit for performing the method. Conventionally, a trained technician has been required to accurately quantitatively determine a number of HHV collected from a body fluid. The method of the present invention is a novel method of quantitative determination that enables measurement of a number of HHV in a body fluid to be simply, accurately, and efficiently determined. The method of the present invention can enable continuous evaluation of the number of HHV in body fluids and, therefore, can be applied to quantitative evaluation of the accumulation of fatigue. | 03-03-2011 |
| 20100331301 | AZETIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF - Compounds of formula [I]: | 12-30-2010 |
| 20100330701 | USE OF HEAT-RESISTANT BIOTIN-BINDING PROTEIN, AND SOLID SUPPORT HAVING THE PROTEIN ATTACHED THERETO - The present invention relates to a solid support having a heat-resistant biotin-binding protein attached thereto. The present invention also relates to the use of the solid support of the present invention having a heat-resistant biotin-binding protein attached thereto. The present invention further relates to technical fields such as purification, concentration, detection and/or capture of a biotin-linked substance by means of a heat-resistant biotin-binding protein. Such a biotin-binding protein used in the solid support of the present invention is heat-resistant and is therefore useful for use in assay systems involving exposure to a temperature of 70° C. or more. | 12-30-2010 |
| 20100305958 | DATA PROCESSING SYSTEM, COMPUTER PROGRAM USED THEREFOR, AND DATA PROCESSING METHOD - A temperature sensing unit senses a plurality of specific temperatures caused by a specific consumable commodity consumed by an ordinary consumer at a specific space, while allowing a behavior storage unit to store q plurality of combinations of the plurality of specific temperatures as a plurality of consumption behaviors of the specific consumable commodity by ordinary consumers. A behavior specifying unit specifies consumption behaviors which match a combination of the plurality of specific temperatures sensed for each piece of the specific consumable commodity, and a data collection unit compiles the specified consumption behavior. Accordingly, data regarding the consumption behaviors of the ordinary consumers, which are uncollectible at the points of time of order intake, production, shipping and selling and so forth of the specific consumable commodity, can be collected. A data processing system capable of efficiently collecting data regarding the consumption behaviors of the specific consumable commodity, such as a cigarette, may be provided. | 12-02-2010 |
| 20100291631 | Novel Beta-Galactoside-Alpha 2,3-Sialyltransferase, a Gene Encoding Thereof, and a Method for Producing Thereof - The present invention provides a novel β-galactoside-α2,3-sialyltransferase and a nucleic acid encoding the sialyltransferase. The present invention also provides a microorganism producing the sialyltransferase, as well as a method for producing the sialyltransferase using such a microorganism. The present invention further provides a vector carrying a nucleic acid encoding the sialyltransferase, and a host cell transformed with the vector, as well as a method for producing a recombinant β-galactoside-α2,3-sialyltransferase. The present invention further provides a method for preparing a sialylsugar chain, which uses the sialyltransferase of the present invention. | 11-18-2010 |
| 20100286416 | PRODUCTION METHOD OF CARBOXYLIC ACID COMPOUND - The present invention provides the production method of carboxylic acid compound, as shown in Scheme I. | 11-11-2010 |
| 20100240634 | Fluorene Compound and Pharmaceutical Use Thereof - The present invention provides an agent for the prophylactic or treatment of diabetes, diabetic complications, insulin resistance syndrome, metabolic syndrome, hyperglycemia, dyslipidemia, atherosclerosis, cardiac failure, cardiomyopathy, myocardial ischemia, brain ischemia, cerebral apoplexy, pulmonary hypertension, hyperlactacidemia, mitochondrial disease, mitochondrial encephalomyopathy or cancer, namely, a PDHK inhibitor and the like. A compound represented by the following formula [I] or a pharmaceutically acceptable salt thereof, or a solvate thereof: | 09-23-2010 |
| 20100240613 | PYRIMIDINE COMPOUND AND MEDICAL USE THEREOF - The present invention relates to a pyrimidine compound or a pharmaceutically acceptable salt thereof represented by the following formula [I] | 09-23-2010 |
| 20100197736 | CETP ACTIVITY INHIBITORS - The present invention provides a CETP activity inhibitor comprising as an active ingredient a compound represented by the formula (I): | 08-05-2010 |
| 20100132068 | Cosmid Vector For Plant Transformation And Use Thereof - The present invention aims to provide novel vectors for plant transformation. | 05-27-2010 |
| 20100132066 | AGROBACTERIUM-MEDIATED METHOD FOR PRODUCING TRANSFORMED PLANT WITHOUT SELECTION STEP - The present invention aims to provide a novel | 05-27-2010 |
| 20100112616 | NOVEL BETA-GALACTOSIDE-a2,6-SIALYLTRANSFERASE, A GENE ENCODING THEREOF, AND A METHOD FOR ENHANCING ENZYME ACTIVITY - The present invention provides an extremely useful and novel β-galactoside-α2,6-sialyltransferase having an optimum reaction pH in a neutral to alkaline range, and a nucleic acid encoding the sialyltransferase. The present invention further provides a vector carrying a nucleic acid encoding the sialyltransferase, and a host cell transformed with the vector, as well as a method for producing a recombinant β-galactoside-α2,6-sialyltransferase. | 05-06-2010 |
| 20100072150 | CIGARETTE DISPLAY SYSTEM, FRAME UNIT, TRAY UNIT, MAGAZINE UNIT, AND SLIDER UNIT - An apparatus main body of a frame structure and an apparatus main body of a wall structure are formed separately, tray units | 03-25-2010 |
| 20100068812 | METHOD FOR INCREASING TRANSFORMATION EFFICIENCY IN PLANTS, COMPRISING COCULTURE STEP FOR CULTURING PLANT TISSUE WITH COCULTURE MEDIUM CONTAINING 3, 6-DICHLORO-O-ANISIC ACID - The present invention aims to provide a method for increasing transformation efficiency in plants when compared to conventionally known | 03-18-2010 |
| 20100025345 | CIGARETTE DISPLAY SYSTEM - A cigarette display system | 02-04-2010 |
| 20100022523 | 3-AMINOBENZAMIDE COMPOUNDS AND VANILLOID RECEPTOR SUBTYPE 1 (VR1) INHIBITORS - The present invention relates to a novel 3-aminobenzamide compound represented by the following formula which effectively inhibits vanilloid receptor subtype 1 (VR1) activity (wherein, for example, R | 01-28-2010 |
| 20100012603 | CIGARETTE DISPLAY SYSTEM - In a cigarette display system | 01-21-2010 |
| 20100010219 | METHOD FOR PRODUCING PYRROLIDINE COMPOUND - Provided is a method capable of efficiently producing a compound having a superior HSD1 inhibitory action and a compound useful as a synthetic intermediate therefor, with superior achievability of asymmetric synthesis (i.e., superior selectivity), superior yield, superior safety and superior industrial workability at a low cost. | 01-14-2010 |
| 20090326058 | CaSR Antagonist - A compound represented by the following formula (1), a pharmaceutically acceptable salt thereof or an optically active form thereof: | 12-31-2009 |
| 20090301506 | LOW IGNITION PROPENSITY CIGARETTE, WRAPPING PAPER THEREFOR, AND METHOD OF PRODUCING WRAPPING PAPER - A low ignition propensity cigarette has wrapping paper ( | 12-10-2009 |
| 20090291471 | Novel Beta-Galactoside Alpha 2,6-Sialyltransferase, Gene Coding For The Transferase And Process For Producing The Same - The present invention provides a novel β-galactoside-α2,6-sialyltransferase having high productivity and/or high activity, and a nucleic acid encoding the sialyltransferase. The present invention also provides a microorganism producing the sialyltransferase. The present invention further provides a vector carrying a nucleic acid encoding the sialyltransferase, and a host cell transformed with the vector, as well as a method for producing a recombinant β-galactoside-α2,6-sialyltransferase. | 11-26-2009 |
| 20090221635 | QUINOLINYL AND BENZOTHIAZOLYL MODULATORS - Compounds, compositions and methods are provided that are useful in the treatment or prevention of a condition or disorder mediated by PPARγ. In particular, the compounds of the invention modulate the function of PPARγ. The subject methods are particularly useful in the treatment and/or prevention of diabetes, obesity, hypercholesterolemia, rheumatoid arthritis and atherosclerosis. | 09-03-2009 |
| 20090170908 | SPIRO COMPOUNDS AND PHARMACEUTICAL USE THEREOF - The Spiro compound represented by the following general formula [Ia], its pharmaceutically acceptable salt or a solvate thereof | 07-02-2009 |
| 20090155273 | REMEDIES FOR INFLAMMATORY BOWEL DISEASES - Antibodies against AILIM (also called ICOS and 8F4) were found to significantly suppress the onset of inflammatory bowel diseases (especially Crohn's disease and colitis (ulcerative colitis and such)), and exhibit a significant therapeutic effect against inflammatory bowel diseases. | 06-18-2009 |
| 20090148444 | PHARMACEUTICAL COMPOSITION FOR TREATING IMMUNE DISEASES - An antibody against AILIM (alternatively called JTT-1 antigen, JTT-2 antigen, ICOS and 8F4) was found to have a significant therapeutic effect on arthrosis, for example, rheumatoid arthritis and osteoarthritis, graft versus host disease, graft immune rejection, inflammation (hepatitis and inflammatory bowel diseases), diseased condition accompanied by the excessive production of an antibody against a foreign antigen triggered by immunological sensitization by the antigen. | 06-11-2009 |
| 20090087894 | Method for improving enzymatic activity of glycosyltransferases - The present invention provides an inexpensive and simple method which allows efficient glycosylation with glycosyltransferases derived from microorganisms of the Vibrionaceae family when compared to conventional enzymatic reaction systems. | 04-02-2009 |
| 20090064575 | Method for Evaluating Deep Rooting Property of Plant - The present invention relates to a method of evaluating multiple plant individuals or plant lines for deep rooting property under the same culture medium moisture conditions. A method of the present invention is a method of evaluating multiple plant individuals for deep rooting property under the same culture medium moisture conditions, by planting multiple plant individuals together in a sufficiently deep culture vessel and lowering the culture medium moisture content gradually. The present invention also provides a method for evaluating plants for deep rooting property, wherein a culture vessel is installed in a water tank so that the culture medium moisture content can be readily adjusted, and thus management of cultivation conditions is facile and efficient. It is possible to select a plant which can grow in dry and low-groundwater level environment efficiently, by using the method of the present invention. Thus, the method of the present invention can find application in breeding a crop suitable for dry land cultivation and trees usable in desert greening. | 03-12-2009 |
| 20090047292 | GRAFT REJECTION SUPPRESSORS - Graft rejection is a serious problem associated with tissue or organ transplantation (e.g., allotransplantation or xenotransplantation), performed to treat various organ failures (e.g., liver, heart, lung, kidney, or pancreas). Described are pharmaceutical compositions for suppressing, treating, or preventing graft rejection comprising a substance having an activity to modulate signal transduction mediated by AILIM, and a pharmaceutically acceptable carrier. | 02-19-2009 |
| 20090038965 | Cigarette package and method of producing same - A cigarette package is provided with a box body ( | 02-12-2009 |
| 20090036450 | PYRAZOLE COMPOUNDS AND USE THEREOF - The pyrazole compound of the present invention is represented by the following general formula (I). The pyrazole compound of the present invention or a salt thereof or a solvate thereof potently inhibits liver glycogen phosphorylase, and, therefore, is useful as a therapeutic or prophylactic agent for diabetes. | 02-05-2009 |
| 20090036444 | 5-5-Membered fused heterocyclic compound and use thereof as HCV polymerase inhibitor - The present invention relates to a fused ring compound represented by the following formula [I] | 02-05-2009 |
| 20080316483 | Mixture indentification system - A mixture identification system for detecting foreign matter admixed in a tobacco material (T) includes a conveyor ( | 12-25-2008 |
| 20080312228 | PYRIMIDINE COMPOUND AND MEDICAL USE THEREOF - The present invention relates to a pyrimidine compound or a pharmaceutically acceptable salt thereof represented by the following formula [I] | 12-18-2008 |
| 20080305169 | Pharmaceutical Compositions Comprising Nitrogen-Containing Fused Ring Coumpounds - [Problems] The present invention provides pharmaceutical composition which is effective for the prophylaxis or treatment of pathology showing involvement of uric acid (hyperuricemia, gouty tophus, acute gout arthritis, chronic gout arthritis, gouty kidney, urolithiasis, renal function disorder, coronary arterial disease, ischemic heart disease and the like) and the like, and is superior in the time-course stability and dissolution property (disintegration property).
| 12-11-2008 |
| 20080301832 | Method for Screening Genomic Dna Fragments - The present invention provides a method for selecting genomic DNA fragments which are useful for providing a plant with an agriculturally advantageous improvement. | 12-04-2008 |
| 20080300957 | Simulation Apparatus, Effect Measurement Apparatus, and Sales Promotion Support System - There is provided a simulation apparatus that predicts an effect of sending out a direct mail for a product of a specific brand, including a planned budget acceptance unit | 12-04-2008 |
| 20080255042 | CaSR Antagonist - A compound represented by the following formula (1), a pharmaceutically acceptable salt thereof or an optically active form thereof: | 10-16-2008 |
| 20080248031 | CELL SURFACE MOLECULE MEDIATING CELL ADHESION AND SIGNAL TRANSMISSION - Novel cell surface molecules recognized by monoclonal antibodies against a cell surface molecule of lymphocytic cells that play an important role in autoimmune diseases and allergic diseases have been isolated, identified, and analyzed for their functions. The cell surface molecules are expressed specifically in thymocytes, lymphocytes activated by ConA-stimulation, and peripheral blood lymphocytes, and induce cell adhesion. Antibodies against the cell surface molecules significantly ameliorate pathological conditions of autoimmune diseases and allergic diseases. | 10-09-2008 |
| 20080199466 | HUMAN MONOCLONAL ANTIBODY AGAINST A COSTIMULATORY SIGNAL TRANSDUCTION MOLECULE AILIM AND PHARMACEUTICAL USE THEREOF - Immunization of human antibody-producing transgenic mice, which have been created using genetic engineering techniques, with AILIM molecule as an antigen resulted in various human monoclonal antibodies capable of binding to AILIM and capable of controlling a variety of biological reactions (for example, cell proliferation, cytokine production, immune cytolysis, cell death, induction of ADCC, etc.) associated with AILIM-mediated costimulatory signal (secondary signal) transduction. Furthermore, it has been revealed that the human monoclonal antibody is effective to treat and prevent various diseases associated with AILIM-mediated costimulatory signal transduction, being capable of inhibiting the onset and/or advancement of the diseases. | 08-21-2008 |
