| ISIS INNOVATION LTD. Patent applications |
| Patent application number | Title | Published |
|---|
| 20120078084 | SYSTEMS AND METHODS FOR SHORTENED LOOK LOCKER INVERSION RECOVERY (Sh-MOLLI) CARDIAC GATED MAPPING OF T1 - A shortened version of the MOLLI sequence (Sh-MOLLI) is described which generates rapid and high-resolution myocardial spin-lattice (T1) maps. The Sh-MOLLI technique is based on a significant abbreviation of pre-existing TI sampling scheme combined with the use of processing logic to bypass the major side effects of the above sampling scheme abbreviation and distinguish between long and short T1 relaxation times in order to conditionally utilize available TI samples for non-linear T1 fitting. | 03-29-2012 |
| 20110309726 | ELECTRIC MACHINE- MODULAR - An electric machine ( | 12-22-2011 |
| 20110309699 | ELECTRIC MACHINE-COOLING - An electric machine ( | 12-22-2011 |
| 20110309694 | ELECTRIC MACHINE- FLUX - An electric machine ( | 12-22-2011 |
| 20110237550 | 5-AZAINDOLE BISPHOSPHONATES - Novel 5-azaindole bisphosphonate compounds are disclosed, as well as methods of preparing the compounds, pharmaceutical compositions including the compounds, and administration of the compounds in methods of treating abnormal calcium and phosphate metabolism, including bone and joint diseases and other disorders. | 09-29-2011 |
| 20110230443 | IMIDAZO[1,2-a] PYRIDINYL BISPHOSPHONATES - Novel imidazo[1,2-α]pyridinyl bisphosphonate compounds are disclosed, as well as methods of preparing the compounds, pharmaceutical compositions including the compounds, and administration of the compounds in methods of treating abnormal calcium and phosphate metabolism, including bone and joint diseases and other disorders. | 09-22-2011 |
| 20100329652 | ELECTRICITY GENERATOR - A wind turbine and generator arrangement comprises a turbine that drives a self-excited induction generator via a shaft and mechanical gearbox. The induction generator includes an electrical circuit that includes a variable capacitance and a variable resistance. The variable capacitance may be constituted by a fixed capacitor and a triac under the control of a controller, or by a bank of capacitors switched by a relay under control of the controller. The variable resistance includes a triac controlled resistor or a bank of relay-switched resistors which constitute heating elements for heating domestic hot water. In use the generator frequency and voltage are allowed to ‘float’ whilst the optimal generator power output is maintained, but adjusting the impedance of the electrical circuit as the wind speed varies. | 12-30-2010 |
| 20100291061 | PROCESS FOR MAKING OLIGOPEPTIDES - There is described a method of synthesising a family of oligopeptides of predetermined amino acid sequence, which together make up from 7 amino acids to the complete amino acid sequence of a target protein, which comprises: synthesising a nucleic acid construct which codes for a fusion protein composed of overlapping peptides derived from the desired portion of the target protein, interspersed with regions which code for protease cleavage sites, expressing the nucleic acid construct in a suitable expression vector, harvesting the fusion protein corresponding to the nucleic acid sequence, and digesting the fusion protein with a protease selective for the cleavage sites to generate the oligopeptides. The oligopeptides may be generated in vitro or in vitro and may be used as vaccines against viral infections and in epitope mapping. | 11-18-2010 |
| 20100279317 | Method - The present invention provides a method for identifying a single or group of T cell receptors (TCR) protective and/or effective against a disease, having the following steps: i) obtaining T cells from a donor non-human animal; ii) adoptive transfer of the T cells into a plurality of T cell-deficient recipient non-human animals in a number such that at least one recipient animal is protected against the disease but at least one animal remains unprotected; and iii) determination of the TCR(s) present only in the protected animals. These TCR can be used to identify the determinants or antigens for inclusion in a vaccine or other treatment. | 11-04-2010 |
| 20100183676 | COMPOSITIONS COMPRISING OPA PROTEIN EPITOPES - The present invention relates to a composition comprising at least one purified Opa HV 1 protein epitope and at least one purified Opa HV2 protein epitope. The epitopes are preferably purified protein epitopes, preferably recombinant epitopes. The composition is preferably a pharmaceutical composition, more preferably a vaccine composition. The invention also relates to methods of immunisation and to specific formulations presented in the tables, and to novel nucleic acids encoding Opa alleles. | 07-22-2010 |
| 20100147705 | Amperometric Sensor and Method for the Detection of Gaseous Analytes Comprising A Working Electrode Comprising Edge Plane Pyrolytic Graphite - An electrochemical sensor and method of detecting gaseous analytes are provided, which involve the use of a working electrode comprising edge plane pyrolytic graphite. | 06-17-2010 |
| 20100134662 | IMAGE CAPTURE DEVICE AND METHOD - An image capture device ( | 06-03-2010 |
| 20100130382 | Liposome, Proteoliposome, Biochip, and Method for Producing Liposome and Proteoliposome - A liposome comprising a region of a lipid bilayer membrane with different membrane thicknesses, wherein each lipid bilayer membrane region is composed of a different lipid, and a thick membrane side in the region of the lipid bilayer membrane is formed of lipid having a phase transition temperature higher than that of the lipid forming a thin membrane side in the region of the lipid bilayer membrane. A proteoliposome, wherein the above-described liposome includes membrane proteins. A biochip, wherein the above-described liposome or the above-described proteoliposome is spread on a substrate. The above-described biochip, wherein the substrate includes at least one kind selected from the group consisting of mica, SiO | 05-27-2010 |
| 20100129433 | Proteoliposome, Production Method Thereof, and Biochip - A proteoliposome, which is obtained by removing a surfactant from a mixed solution including lipid, membrane proteins and the surfactant, wherein the content of the surfactant in the mixed solution is equal to or more than 1.5 times of the sum of a maximum amount of the surfactant associating with the lipid and a maximum amount of the surfactant associating with the membrane protein. A biochip wherein the above-described proteoliposome is spread on a substrate. A method for producing a proteoliposome by removing a surfactant from a mixed solution including lipid, membrane proteins and the surfactant, wherein the content of the surfactant in the mixed solution is made equal to or more than the sum of a maximum amount of the surfactant associating with the lipid and a maximum amount of the surfactant associating with the membrane protein. | 05-27-2010 |
| 20100113549 | PYRROLIDINE COMPOUNDS - The present invention relates to a process for the preparation of a pyrrolidone compound of the formula (I): where R | 05-06-2010 |
| 20100016560 | Vaccine - The invention relates to a vaccine for the treatment of disease caused by | 01-21-2010 |
| 20100015175 | Vaccine - The invention relates to a vaccine for the treatment of disease caused by | 01-21-2010 |
| 20100010211 | Vaccine - The invention relates to a vaccine for the treatment of disease caused by | 01-14-2010 |
| 20100010210 | Vaccine - The invention relates to a vaccine for the treatment of disease caused by | 01-14-2010 |
| 20090206838 | Systems and Methods for Correction of Inhomogeneities in Magnetic Resonance Images - Intensity inhomogeneities can obscure areas of interest and are problematic for MR image segmentation algorithms. An efficient approach to estimating these inhomogeneities by computing a calibration factor that is a function of an estimated bias field from a series of calibration scans is disclosed. This enables correction of T | 08-20-2009 |
| 20090006395 | SHAPE RECOGNITION METHODS AND SYSTEMS FOR SEARCHING MOLECULAR DATABASES - The present disclosure presents novel shape comparison methods. Methods for determining shape similarity between a query molecule and a target molecule and methods for screening one or more molecules in a database based on shape similarity to a query molecule are described. | 01-01-2009 |
| 20080311048 | Imaging Agent - The invention provides a conjugate comprising an iron containing colloidal particle, the particle being conjugated to one or more sugar targeting moieties. The conjugate is useful as a contrast agent in medical imaging, particularly in magnetic resonance imaging (MRI). The agents of the present invention may cross the blood brain barrier and so may be particularly useful in the monitoring or diagnosis of conditions affecting the brain. | 12-18-2008 |
