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INTAS PHARMACEUTICALS LIMITED

INTAS PHARMACEUTICALS LIMITED Patent applications
Patent application numberTitlePublished
20110282094PROCESS FOR PREPARATION OF PHENOLIC MONOESTERS OF HYDROXYMETHYL PHENOLS - A process for the preparation of phenolic monoesters of 2-(3-diisopropylamino-1-phenylpropyl)-4-(hydroxymethyl)phenol by converting (±)6-halo-4-phenylchroman-2-one to (±)4-halo-2-(3-hydroxy-1-phenylpropyl)phenol. The two hydroxyl groups are protected and the protected compound is reacted with diisopropylamine to give (±)[3-(2-benzyloxy-5-halophenyl)-3-phenylpropyl]diisopropylamine. The halo substituent on the benzene ring is converted to corresponding benzyl alcohol and then the protection is removed to give racemic 5-HMT. Racemic 5-HMT is converted R enantiomer and then it is esterified.11-17-2011
20110177137NOVEL DOSAGE FORM OF PALIPERIDONE AND PROCESS FOR PREPARING THE SAME - The present invention relates to an extended release composition of paliperidone for oral administration comprising paliperidone and at least one matrixing agent. The said extended release composition maintains desired therapeutic drug effect over a prolonged period of time and thereby reduces the side effects resulting due to excess drug blood plasma concentration. Further, the invention also relates to process for the preparation of an extended release oral composition of paliperidone.07-21-2011
20110098506METHOD OF PREPARING O-DESMETHYLVENLAFAXINE - A method of preparing O-desmethylvenlafaxine from Venlafaxine or its pharmaceutically acceptable salt is disclosed. The disclosed method involves the use of mercapto carboxylic acids in the presence of suitable solvents under alkaline conditions. The disclosed process provides a novel and industrially feasible process for the preparation of O-desmethylvenlafaxine. The disclosed process also provides a cost effective, non-hazardous and efficient process for preparing O-desmethylvenlafaxine.04-28-2011
20100267824STABLE OXALIPLATIN COMPOSITION FOR PARENTERAL ADMINISTRATION - The present invention relates to a stable parenteral composition of oxaliplatin having pH range in between 3 to 4.5, which comprises of a solution of oxaliplatin in water wherein the said pH is attained by sparging of carbon dioxide in the composition. Further, a method for the preparation of oxaliplatin composition of the present invention is also disclosed.10-21-2010
20090275647TAXANE DERIVATIVE COMPOSITION - A stable, absolutely ethanol free composition of docetaxel that prevents alcoholic intoxication or anaphylactic shock. The composition can be in the form of a stable injectable composition that includes a taxane derivative, wherein the composition includes a mixture of docetaxel, one or more stabilizer, one or more surfactant, or more co-solvent and water for injection wherein the composition is absolutely free of ethanol.11-05-2009

Patent applications by INTAS PHARMACEUTICALS LIMITED