| INSTITUT GUSTAVE ROUSSY (IGR) Patent applications |
| Patent application number | Title | Published |
|---|
| 20100060644 | METHOD AND SYSTEM FOR QUANTIFICATION OF TUMORAL VASCULARIZATION - The invention relates to a method and system for processing a test signal in medical domain comprising following steps:—acquiring ( | 03-11-2010 |
| 20090286720 | PHARMACEUTICAL COMPOSITION FOR THE DIAGNOSIS, PREVENTION OR TREATMENT OF A TUMORAL PATHOLOGY COMPRISING AN AGENT MODULATING THE POLYMERIZATION STATE OF ACTIN - A pharmaceutical composition for the treatment, prevention or diagnosis of a tumoral pathology comprising an active agent which stabilizes an actin network of a cellular cytoskeleton. | 11-19-2009 |
| 20090269363 | METHOD FOR SCREENING PEPTIDES FOR USE IN IMMUNOTHERAPY - Identifying subdominant/cryptic epitopes (I) that are presented by a HLA (human leukocyte antigen) Class I molecule, is new. Identifying subdominant/cryptic epitopes (I) that are presented by a HLA (human leukocyte antigen) Class I molecule comprising selecting at least one peptide (II) of 8-11 amino acids (aa), potentially representing an epitope for Class I presentation, from a protein against which a cytotoxic T cell (CTL) response is to be raised. (II) corresponds to a non-immunogenic peptide with low affinity for Class I molecules. Variants (IIa) of (II) are prepared in which the N-terminal aa is replaced by Tyr and their immunogenicity detected by identifying those that generate a CTL response against target cells expressing the parent protein. Peptide sequences from which active (IIa) are derived are then identified. Independent claims are also included for the following: (1) immunogenic peptide epitopes (IIa) derived from (I) identified this way; and (2) nucleic acid (III) that encodes chimeric polypeptides (IV) containing one or more, same or different, copies of (IIa). | 10-29-2009 |
