INJE UNIVERSITY INDUSTRY- ACADEMIC COOPERATION FOUNDATION Patent applications |
Patent application number | Title | Published |
20160116458 | CELL MODEL FOR NEOVASCULAR DISEASES USING EBV-INFECTED HUMAN CORNEAL EPITHELIAL CELLS - The present invention relates to a cell model for diseases associated with corneal neovascularization by using Epstein Barr virus (EBV)-infected human corneal epithelial cells (HCECs). Provided are a method for preparing a cell model for diseases associated with corneal neovascularization by using EBV-infected HCECs, the method including: infecting HCECs with EBV; culturing the infected HCECs; and determining whether the cultured HCECs are infected with EBV. In addition, provided is a method for screening diseases associated with corneal neovascularization prepared by the cell model for diseases associated with corneal neovascularization. | 04-28-2016 |
20150275386 | METHOD FOR PREPARING NANOSTRUCTURE BY ELECTROCHEMICAL DEPOSITION, AND NANOSTRUCTURE PREPARED THEREBY - The present invention relates to a method for preparing a nanostructure by electrochemical deposition, and a nanostructure prepared thereby, and more specifically, to: a method for preparing a nanostructure by electrochemical deposition, wherein it is possible to prepare a nanostructure having remarkable morphological, structural and optical characteristics by controlling a method for applied power during electrochemical deposition; and a nanostructure prepared thereby. | 10-01-2015 |
20150252030 | N-ACYLHYDRAZONE DERIVATIVES FOR SELECTIVE T CELL INHIBITOR AND ANTI-LYMPHOID MALIGNANCY DRUG - The present invention relates to novel N-acylhydrazone derivatives, and more particularly to novel N-acylhydrazone derivatives having selective T cell inhibitory activity and/or anti-lymphoid malignancy activity, stereoisomers thereof, pharmaceutically acceptable salts thereof, the use thereof for preparing pharmaceutical compositions, pharmaceutical compositions containing the same, treatment methods using the compositions, and methods for preparing the novel N-acylhydrazone derivatives. | 09-10-2015 |
20150176026 | REPLICATION COMPETENT PSEUDO-TYPE RETROVIRUS VECTOR SYSTEM - The present invention provides a vector system in which a MuLV-Gag gene, a MuLV-Pol gene, and a GaLV-Env gene are expressed in two separate vectors. The vector system is capable of inserting a therapeutic gene to these two separate vectors, and in this raged, the size of an inserted gene is not limited and a variety of foreign therapeutic genes may be inserted to the vectors. Accordingly, the foreign therapeutic gene may be delivered in a safe and efficient manner to desired tissue of cells of aberrant proliferation. Therefore, the vector system is applicable in a composition for delivering a gene targeting the aberrantly dividing cells of aberrant proliferation, wherein the composition includes a retrovirus produced by cell line transfection. The vector system is also applicable in a composition for preventing or treating a disease caused by cells of aberrant proliferation of, such as cancer cells. | 06-25-2015 |
20150153324 | NON-INVASIVE METHOD FOR MEASURING PROLIFERATION AND DIFFERENTIATION STATE OF CELLS BY USING MAGNETIC RESONANCE SPECTROSCOPY, AND CELL PROLIFERATION AND DIFFERENTIATION MARKER FOR MAGNETIC RESONANCE SPECTROSCOPY USED THEREFOR - Provided are a noninvasive measurement of cell signals and a method thereof, wherein the measurement method can ascertain cell proliferation and differentiation states using MRS and can enable cells to be reused so that cell states can be evaluated with improved reproducibility and reliability. And since the cell signals are noninvasively measured using the MRS, the corresponding cells can be reused so that the cost and time needed for one experiment can be remarkably reduced. | 06-04-2015 |
20150132225 | PTERYGIUM ANIMAL MODEL USING HUMAN PTERYGIAL EPITHELIAL CELLS - Provided is a pterygium animal model produced by injecting human-derived pterygial epithelial cells that are isolated and cultured in vitro. The animal model has characteristics similar to those of pterygium, which are observed only in humans, wherein such characteristics are caused in such a way that pterygial epithelial cells are isolated from human pterygium corneal tissues and cultured, the cultured pterygial epithelial cells are sub-cultured, and human-derived pterygial epithelial cells of which identify is confirmed are injected into the nasal subconjunctival space of mice. The pterygium animal model allows a pterygium therapeutic agent to be effectively screened. | 05-14-2015 |
20150054496 | MULTI-FUNCTIONAL MEASURING AND WAVEFORM-GENERATING EQUIPMENT WITH PROBE - There is provided a Multi-functional measuring and waveform-generating equipment with a probe. The equipment is capable of measuring element values of electric or electronic devices and electrical quantities such as a voltage, and generating electrical signals with various waveforms. Also, a user can conveniently manipulate and handily carry it. The equipment provides functions of measuring a voltage, a resistance, an inductance, capacitance, a frequency, the number of pulses, and the voltage level of a logic signal; verifying diode polarities, measuring the voltage level of a pulse signal, and modes generating a rectangular pulse train and a PWM signal by the simple combinations of two switches. Additionally, it also offers a much cheaper equipment than other existing expensive apparatuses, and provide better usability at experimental environments because it is small-sized, light, and conveniently portable, compared to conventional equipments that are large-sized, heavy, and not easy to carry. | 02-26-2015 |
20140242694 | COMPOSITION CONTAINING COMPLEX CYTOKINES DERIVED FROM EBV-INFECTED B CELLS FOR INDUCING THE MATURATION OF DENDRITIC CELLS - A composition for deriving the maturation of dendritic cells includes complex cytokines generated by the simulation, the expression of which is induced on EBV-infected B cells. The dendritic cell maturation process, which conventionally takes approximately 7 days, can be shortened to 2 days, thereby producing dendritic cells in a more economically advantageous and effective manner. | 08-28-2014 |
20140012393 | COMPLEX SUPPORT BODY FOR REGENERATING BONE-CARTILAGE, METHOD FOR MANUFACTURING THEREOF, AND COMPOSITION FOR TREATING BONE AND CARTILAGE RELATED DISEASES COMPRISING SAME AS ACTIVE INGREDIENT - The present invention relates to a complex support body for regenerating bone-cartilage, a method for manufacturing thereof, and a composition for treating bone and cartilage related diseases comprising the same as an active ingredient, and more particularly, to a complex support body for regenerating bone-cartilage, which comprises a bone regeneration layer consisting of a biodegradable polymer and a biocompatible ceramic, and a cartilage regeneration layer, which is coupled to the bone regeneration layer and in which cells that can be differentiated into cartilages cells are fixed; a method for manufacturing thereof; and a composition for treating bone and cartilage related diseases comprising the same as an active ingredient. The complex support body of the present invention for regenerating bone-cartilage is manufactured as a three-dimensional support body, which is similar to a living tissue, according to a bioplotting method, and exerts the effect of regeneration into a bone tissue and a cartilage tissue, respectively, depending on materials encountered in the environment where the complex support body for regenerating bone-cartilage is used. | 01-09-2014 |
20130295060 | METHOD FOR CULTURING CARDIAC PROGENITOR CELLS AND USE OF CARDIAC PROGENITOR CELLS - Disclosed is a method for culturing myocardium-resident cardiac progenitor cells, comprising: embedding myocardial fragments into hydrogel; culturing the myocardial fragment into hydrogel; degrading only the hydrogel to recover cardiac progenitor cells grown out of the myocardial fragment to the hydrogel; and amplifying the cardiac progenitor cells in vitro. Also, the cardiac progenitor cells, a method for differentiating the same, and the use thereof as cell therapeutic agent for heart diseases are provided. In addition to possessing the potential to differentiate into cardiomyocytes, osteoblasts, adipocytes, chondrocytes, vascular endothelial cells, smooth muscle cells, neural cells, and skeletal muscle cells, the myocardium-resident cardiac progenitor cells can spontaneously differentiate into cardiomyocytes even in the absence of a special differentiation inducing agent. Thus, the cardiac progenitor cells can be used to produce bio-active medicines such as cell therapeutics and tissue engineering therapeutics with high industrial applicability. | 11-07-2013 |
20130240033 | METHOD FOR PRODUCING COUNTER ELECTRODE BASED ON ELECTROPHORETIC DEPOSITION OF GRAPHENE, COUNTER ELECTRODE PRODUCED BY THE METHOD AND DYE-SENSITIZED SOLAR CELL INCLUDING THE COUNTER ELECTRODE - Disclosed is a method for producing a counter electrode based on electrophoretic deposition of graphene. The method includes: adding graphene to a dispersion medium to prepare a graphene dispersion; dipping a transparent electrode in the graphene dispersion and applying a voltage to the transparent electrode for 5 seconds to 5 minutes to deposit the graphene on the transparent electrode; and annealing the graphene-adsorbed transparent electrode at 350 to 600° C. under a nitrogen atmosphere. Also disclosed are a counter electrode produced by the method and a dye-sensitized solar cell including the counter electrode. | 09-19-2013 |
20130203095 | METHOD OF SCREENING PLACENTAL PROTEINS RESPONSIBLE FOR PATHOPHYSIOLOGY OF PREECLAMPSIA, AND MARKER FOR EARLY DIAGNOSIS AND PREDICTION OF PREECLAMPSIA - The present invention relates to a method of screening placental proteins responsible for pathophysiology of preeclampsia, and a marker for early diagnosis and prediction of preeclampsia. In accordance with one aspect of the present invention, there is provided a method of screening placental proteins responsible for pathophysiology of preeclampsia by 2D E-proteomics analysis, comprising: isolating placental proteins from a placental tissue; separating the isolated proteins two-dimensionally through 2D electrophoresis; and comparing and analyzing the separated proteins based on scanned gel images and differences in the images between normal placental proteins and preeclamptic placental proteins, wherein the comparison and analysis of the placental proteins based on the scanned gel images and differences in the images are accomplished by selecting proteins with differences of 140% or more between two placentas. | 08-08-2013 |
20130189755 | APPARATUS FOR SEPARATING FINE PARTICLES USING MAGNETOPHORESIS, AND METHOD FOR SEPARATING FINE PARTICLES USING SAME - The present invention relates to an apparatus for separating fine particles using magnetophoresis, and to a method for separating fine particles using same, and particularly, to an apparatus for separating fine particles using magnetophoresis, which includes a fine, patterned magnetic structure capable of quickly and efficiently separating even particles that are weakly magnetized and coupled to fine particles, and to a method for separating fine particles using same. | 07-25-2013 |
20130175927 | PLASMA TREATMENT APPARATUS USING LEAKAGE CURRENT TRANSFORMER - Provided is a plasma treatment apparatus using a leakage current transformer, the apparatus, including: a chamber which provides a closed space in which plasma is formed, and receives a treated sample in an inner part thereof; an exhaust unit for forming the inner part of the chamber in a vacuum state; plasma generation electrodes fixed in the chamber, positive and negative poles of which are installed to be opposed to each other; a variable power supply which is installed in an outer part of the chamber and supplies a power source to the plasma generation electrodes; and a leakage current transformer which is installed between the variable power supply and the plasma generation electrodes and adjusts voltage and current applied to the plasma generation electrodes. | 07-11-2013 |
20130129578 | APPARATUS FOR SINGLE CELL SEPARATION AND POSITION FIXING - The present invention relates to an apparatus for single cell trap and position fixing of the trapped cell thereof, and specifically, it induces cell movement from where fluid flows strongly to where the fluid flows weakly, by injecting pressed air to an air channel to modify a thin film of a vibrator, and therefore to induce the fluid flow. | 05-23-2013 |
20130096010 | HtSNPs FOR DETERMINING A GENOTYPE OF CYTOCHROME P450 1A2, 2A6 AND 2D6, PXR AND UDP-GLUCURONOSYLTRANSFERASE 1A GENE AND MULTIPLEX GENOTYPING METHODS USING THEREOF - The present invention relates to htSNPs for determining a genotype of cytochrome P450 1A2 (CYP1A2), 2A6 (CYP2A6) and 2D6 (CYP2D6), PXR and UDP-glucuronosyltransferase 1a (UGT1A) genes and a gene chip using the same, and more particularly, to a selection method of htSNPs for determining a haplotype of human CYP1A2, CYP2A6, CYP2D6, PXR and UGT1A genes, a method of determining a genotype of the genes by using the htSNPs and a gene chip therefor. | 04-18-2013 |
20130095478 | HtSNPs FOR DETERMINING A GENOTYPE OF CYTOCHROME P450 1A2, 2A6 AND 2D6, PXR AND UDP-GLUCURONOSYLTRANSFERASE 1A GENE AND MULTIPLEX GENOTYPING METHODS USING THEREOF - The present invention relates to htSNPs for determining a genotype of cytochrome P450 1A2 (CYP1A2), 2A6 (CYP2A6) and 2D6 (CYP2D6), PXR and UDP-glucuronosyltransferase 1a (UGT1A) genes and a gene chip using the same, and more particularly, to a selection method of htSNPs for determining a haplotype of human CYP1A2, CYP2A6, CYP2D6, PXR and UGT1A genes, a method of determining a genotype of the genes by using the htSNPs and a gene chip therefor. | 04-18-2013 |
20120253456 | METHOD FOR PREPARATION OF ARTIFICIAL BLOOD VESSEL USING TUBE-TYPE POROUS BIODEGRADABLE SCAFFOLD HAVING A DOUBLE-LAYERED STRUCTURE AND STEM CELL, AND ARTIFICIAL BLOOD VESSEL MADE BY THE SAME - The present invention relates to a method for preparation of an artificial blood vessel using a tube-type porous biodegradable scaffold having a double layered structure and a stem cell, and an artificial blood vessel made by the same. Specifically, the present invention relates to a method for preparation of an artificial blood vessel by separately seeding a stem cell onto the inner membrane and an outer membrane of a tube-type porous biodegradable scaffold having a double layered structure, wherein the inner membrane and the outer membrane having different biodegradable polymer nano-fiber arrangements are continuously linked, and by inducing differentiation; and an artificial blood vessel made by the same. | 10-04-2012 |
20110059473 | PROTEINS WITH PTERIDINE GLYCOSYLTRANSFERASE ACTIVITY AND ANALYSIS METHOD USING THE SAME - The present invention relates to proteins with pteridine glycosyltransferase activity and an analysis method using the same. Since the proteins glycate tetrahydrobiopterin selectively through an enzyme reaction, the method enables quantitative analysis of tetrahydrobiopterin and oxides thereof at the same time or quantitative analysis of tetrabiopterin selectively. | 03-10-2011 |
20100159454 | HtSNPs FOR DETERMINING A GENOTYPE OF CYTOCHROME P450 1A2, 2A6 AND 2D6, PXR AND UDP-GLUCURONOSYLTRANSFERASE 1A GENE AND MULTIPLEX GENOTYPING METHODS USING THEREOF - The present invention relates to htSNPs for determining a genotype of cytochrome P450 1A2 (CYP1A2), 2A6 (CYP2A6) and 2D6 (CYP2D6), PXR and UDP-glucuronosyltransferase Ia (UGT1A) genes and a gene chip using the same, and more particularly, to a selection method of htSNPs for determining a haplotype of human CYP1A2, CYP2A6, CYP2D6, PXR and UGT1A genes, a method of determining a genotype of the genes by using the htSNPs and a gene chip therefor. | 06-24-2010 |
20100100986 | PROMOTER FOR THE HIGH LEVEL EXPRESSION IN PLANT-TISSUE CULTURE AND VECTOR USING THE SAME - Disclosed herein are a promoter (SEQ ID NO.: 1) inducing high level expression of a target gene in plant tissue cultured cells, derived from the sweetpotato gene of Ran GTPase, small GTP binding protein, a plant transformation vector for carrying the same and a method for expressing a foreign gene in plant cell using the vector. The activity of promoter according to the present invention is higher than that of universal CaMV 35S promoter in transgenic suspension cultured cell lines, calluses and adventitious roots. Thus, the promoter is useful in the generation of transgenic cell lines including cultured roots to produce valuable materials such as medicinal or industrial proteins in a large quantities with plant tissue cultured cells. | 04-22-2010 |