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IMBA-INSTITUT FUR MOLEKULARE BIOTECHNOLOGIE GMBH

IMBA-INSTITUT FUR MOLEKULARE BIOTECHNOLOGIE GMBH Patent applications
Patent application numberTitlePublished
20100317563METHODS FOR MODULATING THE PROLIFERATION AND DIFFERENTIATION POTENTIAL OF STEM CELLS AND PROGENITOR CELLS - Modulators of TRIM-NHL proteins and their use for modulating the proliferation and differentiation potential of stem cells and progenitor cells. Inhibitors of TRIM-NHL proteins, e.g. TRIM32, are useful for stem cell maintenance in vitro and in vivo. Assay methods for identifying TRIM-NHL protein modulators make use of the E3 ligase activity of TRIM32 or its interaction with Argonaute-1.12-16-2010
20090162426Use of a Compound with RANKL Activity - The present invention relates to the use of a compound with receptor activator of nuclear factor-kB ligand (RANKL) activity for the manufacture of a topical pharmaceutical formulation for the modulation of local or systemic Treg numbers and the treatment or the prevention of skin-associated or systemic diseases.06-25-2009