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Ikonisys, Inc.

Ikonisys, Inc. Patent applications
Patent application numberTitlePublished
20120094868DETECTION OF CIRCULATING TUMOR CELLS IN PERIPHERAL BLOOD WITH AN AUTOMATED SCANNING FLUORESCENCE MICROSCOPE - An automated, highly sensitive, specific and potentially quantitative detection method using an automated microscope for identifying and enumerating rare cancer cells in blood and other fluids.04-19-2012
20120075453Method for Detecting and Quantitating Multiple-Subcellular Components - A method for detecting and quantitating multiple and unique fluorescent signals from a cell sample is provided. The method combines immunohistochemistry and a fluorescent-labeled in situ hybridization techniques. The method is useful for identifying specific subcellular components of cells such as chromosomes and proteins.03-29-2012
20120020542SYSTEM FOR DETECTING INFECTIOUS AGENTS USING COMPUTER-CONTROLLED AUTOMATED IMAGE ANALYSIS - A method for providing quantitative information regarding the extent of infection of host cells by an infectious agent. A microscope image of a specimen of a bodily fluid is analyzed using image processing techniques to quantify the percentage of the area of the specimen that is infected.01-26-2012
20110317904IMAGE PROCESSING METHOD FOR A MICROSCOPE SYSTEM - An embodiment is disclosed for performing the image processing for analyzing the results of a fluorescence in situ hybridization (FISH) microscopic automated sample analysis to determine specific chromosomal characteristics.12-29-2011
20110280013FILTER WHEEL - An improved filter wheel is disclosed, through embodiments, that comprises a plurality of reflector support structures formed as a unitized structure with a circular base member. In some embodiments, the filter wheel further comprises a plurality of light sources mounted on the filter wheel.11-17-2011
20110129138SYSTEM FOR DETECTING INFECTIOUS AGENTS USING COMPUTER-CONTROLLED AUTOMATED IMAGE ANALYSIS - A method for recognizing an object in an image is disclosed wherein a fractal map of the image is generated by estimating the fractal dimension of each pixel in the image. The fractal map may be segmented by thresholding and locations of candidate objects are determined. The pixel value of the image pixel corresponding to the same location where the candidate object is found in the fractal map may be compared to a threshold value. If the pixel value is greater than the threshold value, the candidate object is recognized as a valid object.06-02-2011
20110122492CUSTOM FILTRATION SLIDE AND FILTRATION APPARATUS AND METHOD - An filter, apparatus and method for preparing microscope slides is presented. After filtration of the specimen is performed, the filter containing the filtrand is configured to be microscopically examined. The filter may either be affixed to a microscope slide or, in an embodiment, the filter may be incorporated into a microscope slide.05-26-2011
20110079640METHODS FOR DETECTING FLUORESCENT SIGNALS IN A BIOLOGICAL SAMPLE - A method for automated microscopic analysis wherein the test protocol is obtained from interrogatable data affixed to each microscope slide. The method further comprises the algorithms that implement the test protocol.04-07-2011
20100315502SYSTEM AND METHOD FOR REMOTE CONTROL OF A MICROSCOPE - A system and method for remote control of an automated microscope via a widely distributed network.12-16-2010
20100238287SYSTEM AND METHOD FOR FRACTIONATION OF A CENTRIFUGED SAMPLE - The present invention relates generally to a fractionator for collecting at least one of a plurality of segregated components from a segregated sample disposed in a sample tube. The fractionator has a head with a head surface at its forward end. The head may be configured to form a slideable seal with the inside surface of a sample tube. A collection port is disposed forward of the head surface, and a fluid passageway is in fluid communication with the collection port and is configured and arranged to allow fluid transport from the sample tube to a sample receptacle. The fractionator may have a valve in fluid communication with the collection port and may have a valve controller configured and arranged to operate the valve based, at least in part, on the location of the collection port with respect to a sample disposed in the sample tube.09-23-2010
20100203527Process for identifying fish signals - Among embodiments is disclosed a process for immunostaining a sample such that the stain is stable under FISH conditions.08-12-2010
20100046068AUTOMATED MICROSCOPE SLIDE READ SYSTEM - A method and apparatus for automating microscopic analysis of a plurality of data-encoded microscope slides. In embodiments, the data written to or read from the slides may comprise images, analysis protocols, analytic results and other pertinent data. Embodiments also encompass a magazine that contains a plurality of data encoded slides.02-25-2010
20100012822IMAGER SYSTEM - An imager system is disclosed comprising a image intensifier and a CMOS image sensor. The system provides fast capture speed and high sensitivity.01-21-2010
20090280496NON-INVASIVE METHOD FOR DIAGNOSING FETAL CELLS AND CANCER CELLS - A non-invasive method for determining the developmental age of a fetus or detecting cancer cells in a sample is provided. The method utilizes, for example, a sample of blood from a pregnant female and telomeric nucleic acid probes.11-12-2009
20090253145METHOD FOR DETECTING AND QUANTITATING MULTIPLE SUBCELLULAR COMPONENTS - A method for detecting and quantitating multiple and unique fluorescent signals from a cell sample is provided. The method combines immunohistochemistry and a fluorescent-labeled in situ hybridization techniques. The method is useful for identifying specific subcellular components of cells such as chromosomes and proteins.10-08-2009
20090250629Methods for Detecting Fluorescent Signals in a Biological Sample - Operational means for automatic microscopic detection and analysis of fluorescent signals from a treated biological sample.10-08-2009
20090208965AUTOMATED METHOD FOR DETECTING CANCERS AND HIGH GRADE HYPERPLASIAS - Automated methods for detecting cancer and related hyperplasias in biological samples.08-20-2009
20090123054DETECTION OF CIRCULATING TUMOR CELLS IN PERIPHERAL BLOOD WITH AN AUTOMATED SCANNING FLUORESCENCE MICROSCOPE - An automated, highly sensitive, specific and potentially quantitative detection method using an automated microscope for identifying and enumerating rare cancer cells in blood and other fluids.05-14-2009
20090116101MICROSCOPE ENCLOSURE SYSTEM - A light-tight enclosure system for housing an automated microscope.05-07-2009
20090111101Automated Cancer Diagnostic Methods Using FISH - In various embodiments methods for automated screening for gene amplification in biological tissue samples using an automated fluorescence microscope to analyze fluorescence in situ hybridized samples are provided. Various additional embodiments provide methods of high throughput screening for gene amplification.04-30-2009
20090074293METHOD AND SYSTEM FOR OBJECT RECOGNITION USING FRACTAL MAPS - A method for recognizing an object in an image is disclosed wherein a fractal map of the image is generated by estimating the fractal dimension of each pixel in the image. The fractal map may be segmented by thresholding and locations of candidate objects are determined. The pixel value of the image pixel corresponding to the same location where the candidate object is found in the fractal map may be compared to a threshold value. If the pixel value is greater than the threshold value, the candidate object is recognized as a valid object.03-19-2009
20090052795SYSTEM AND METHOD FOR AUTO-FOCUSING AN IMAGE - A method and system for auto-focusing is disclosed where the number of the fractal pixels having a fractal dimension within a predetermined range is determined. The focused image is determined by adjusting the image to maximize the fractal pixel count. Alternatively, the focused image may be selected from a set of images, the image having the largest fractal pixel count selected as the focused image.02-26-2009
20080317566Automated Cassette and Slide Handling System for an Automatic Microscope - An automated cassette and slide handling system is disclosed which organizes microscope slides in cassettes, automatically and sequentially removes individual slides from their respective cassettes, positioned each slide under the microscope as provided by the protocol, and after examination returns the slide to its proper cassette.12-25-2008
20080285837Method for Detecting and Quantitating Multiple-Subcellular Components - A method for detecting and quantitating multiple and unique fluorescent signals from a cell sample is provided. The method combines immunohistochemistry and a fluorescent-labeled in situ hybridization techniques. The method is useful for identifying specific subcellular components of cells such as chromosomes and proteins.11-20-2008
20080268456METHOD FOR DETECTING AND QUANTITATING MULTIPLE-SUBCELLULAR COMPONENTS - A method for detecting and quantitating multiple and unique fluorescent signals from a cell sample is provided. The method combines immunohistochemistry and a fluorescent-labeled in situ hybridization techniques. The method is useful for identifying specific subcellular components of cells such as chromosomes and proteins.10-30-2008
20080241848METHODS FOR PRENATAL DIAGNOSIS OF ANEUPLOIDY - Methods are disclosed for the automated prenatal genetic diagnosis of aneuploidy using an automated fluorescence microscope, conducted on samples of maternal blood that have been hybridized with FISH probes.10-02-2008
20080238674SYSTEM FOR AUTOMATICALLY LOCATING AND MANIPULATING POSITIONS ON AN OBJECT - A system for automatically locating positions on an object and uniquely identifying the object employing an electronic tag positioned in or on the object. The system utilizes a plurality of sensors to locate the electronic tag and identify the object, and triangulation techniques to locate positions on the object where the object may be manipulated according to instructions coded with respect to the positions. Advantageously, the present invention may be used for automatically locating specimens on a microscope slide without regards to their positions on the slide, and for uniquely labeling a microscope slide.10-02-2008
20080231973MECHANISM FOR A MICROSCOPE OBJECTIVE CHANGER AND FILTER CHANGER - A mechanism is disclosed for incorporation into automatic microscope which permits the interchanging of optical path components such as objective lens assemblies, filters, and imaging devices. The mechanism features good placement accuracy and repeatability to permit the maintenance of system calibrations.09-25-2008
20080213902Slide Holder for Staining Procedures - Improvements in FISH staining employing a microscope slide holder which allows for batch processing of slides in the hybridization process.09-04-2008
20080213824Synthesis of Labeled Probes - Improvements in FISH staining employing an aqueous acetonitrile/dimethylsulfoxide mixture in a fluorophore coupling reaction.09-04-2008
20080213769Automated Method for Detecting Cancers and High Grade Hyperplasias - Automated methods for detecting cancer and related hyperplasias in biological samples.09-04-2008
20080212865Image Processing Method for a Microscope System - An embodiment is disclosed for performing the image processing for analyzing the results of a fluorescence in situ hybridization (FISH) microscopic automated sample analysis to determine specific chromosomal characteristics.09-04-2008
20080212172Image Processing Method for a Microscope System - An embodiment is disclosed for performing the image processing for analyzing the results of a fluorescence in situ hybridization (FISH) microscopic automated sample analysis to determine specific chromosomal characteristics.09-04-2008
20080206774AUTOMATED CANCER DIAGNOSTIC METHODS USING FISH - In various embodiments methods for automated screening for gene amplification in biological tissue samples using an automated fluorescence microscope to analyze fluorescence in situ hybridized samples are provided. Various additional embodiments provide methods of high throughput screening for gene amplification.08-28-2008
20080199948SYSTEM FOR DETECTING INFECTIOUS AGENTS USING COMPUTER-CONTROLLED AUTOMATED IMAGE ANALYSIS - A method for recognizing an object in an image is disclosed wherein a fractal map of the image is generated by estimating the fractal dimension of each pixel in the image. The fractal map may be segmented by thresholding and locations of candidate objects are determined. The pixel value of the image pixel corresponding to the same location where the candidate object is found in the fractal map may be compared to a threshold value. If the pixel value is greater than the threshold value, the candidate object is recognized as a valid object.08-21-2008
20080198450Z-MOTION MICROSCOPE SLIDE MOUNT - A microscope slide mount capable of z-axis movement.08-21-2008

Patent applications by Ikonisys, Inc.