| IEP GMBH Patent applications |
| Patent application number | Title | Published |
|---|
| 20120040425 | PROCESS FOR THE STEREOSELECTIVE ENZYMATIC REDUCTION OF KETO COMPOUNDS - In a process for the stereoselective, in particular enantioselective enzymatic reduction of keto compounds to the corresponding chiral hydroxy compounds, wherein the keto compounds are reduced with an enantioselective, NADH-specific oxidoreductase, a polypeptide is used for reducing the keto compounds, which polypeptide exhibits an R-ADH-signature H-[P; A]-[I; A; Q; V; L]-[G; K]-R at positions 204-208 and the following further structural features in their entirety:
| 02-16-2012 |
| 20120040424 | PROCESS FOR THE ENANTIOSELECTIVE ENZYMATIC REDUCTION OF SECODIONE DERIVATIVES - The invention relates to a process for the enantioselective enzymatic reduction of secodione derivatives. The secodione derivative is reduced with an oxidoreductase/dehydrogenase in the presence of NADH or NADPH as a cofactor. The secodione derivative is used in the reaction batch at a concentration of ≧10 g/l and the oxidized cofactor NAD or NADP formed by the oxidoreductase/dehydrogenase is regenerated continuously. | 02-16-2012 |
| 20110020887 | PROCESS FOR THE ENANTIOSELECTIVE ENZYMATIC REDUCTION OF SECODIONE DERIVATIVES - The invention relates to a process for the enantioselective enzymatic reduction of secodione derivatives. | 01-27-2011 |
| 20100248317 | PROCESS FOR THE ENANTIOSELECTIVE ENZYMATIC REDUCTION OF INTERMEDIATES - A process for the enantioselective enzymatic reduction of a keto compound of general formula I | 09-30-2010 |
| 20090311762 | OXIDOREDUCTASES FOR THE STEREOSELECTIVE REDUCTION OF KETO COMPOUNDS - The invention relates to a process for the enantioselective enzymatic reduction of a keto compound to the corresponding chiral hydroxy compound, wherein the keto compound is reduced with an oxidoreductase in the presence of a cofactor, and is characterized in that an oxidoreductase is used which has an amino acid sequence in which (a) at least 70% of the amino acids are identical to the amino acids of one of the amino acid sequences SEQ ID No 1, SEQ ID No 6 and SEQ ID No 8, or (b) at least 55% of the amino acids are identical to the amino acids of the amino acid sequence SEQ ID No 2, or (c) at least 65% of the amino acids are identical to the amino acids of the amino acid sequence SEQ ID No 3, or (d) at least 75% of the amino acids are identical to the amino acids of the amino acid sequence SEQ ID No 4, or (e) at least 65% of the amino acids are identical to the amino acids of the amino acid sequence SEQ ID No 5, or (f) at least 50% of the amino acids are identical to the amino acids of the amino acid sequence SEQ ID No 7, or (g) at least 72% of the amino acids are identical to the amino acids of the amino acid sequence SEQ ID No 129. | 12-17-2009 |
| 20090280525 | PROCESS FOR THE ENANTIOSELECTIVE REDUCTION AND OXIDATION, RESPECTIVELY, OF STEROIDS - A process for the enantioselective enzymatic reduction of compounds which comprise a steroid structure (ABCD) including one or several heteroatoms, one or several double bonds and/or one aromatic component in the ring structure and have at least one oxo group at position 3, 7, 11, 12 or 17 in the steroid ring system or in the α-position at any carbon moiety on the steroid skeleton (=oxosteroid compound), | 11-12-2009 |
| 20090221044 | Process for the Enantioselective Enzymatic Reduction of Hydroxy Keto Compounds - In a process for the enantioselective enzymatic reduction of a hydroxy ketone of general formula I | 09-03-2009 |
| 20090148917 | METHOD FOR PRODUCING CHIRAL ALCOHOLS - The invention relates to a method for producing an enantiopure alcohol of general formula (Ia) or (Ib), wherein R | 06-11-2009 |
| 20080233619 | Process For the Enantioselective Enzymatic Reduction of Keto Compounds - The present invention relates to a process for the enantioselective enzymatic reduction of keto compounds which is carried out in two phases and uses 4-methyl-2-pentanol, 5-methyl-2-hexanol and/or 2-heptanol for coenzyme regeneration. | 09-25-2008 |
