| HUNTINGTON MEDICAL RESEARCH INSTITUTES Patent applications |
| Patent application number | Title | Published |
|---|
| 20110095759 | METHODS AND APPARATUS FOR PASADENA HYPERPOLARIZATION - The present subject matter relates to methods and apparatus for using hyperpolarization to improve imaging. Am exemplary embodiment, a PASADENA polarizer, is capable of delivering 2.5-5 ml of highly hyperpolarized biological | 04-28-2011 |
| 20100233089 | IMAGING OF GENETIC MATERIAL WITH MAGNETIC RESONANCE - A method for imaging genetic material such as DNA, RNA and genes by magnetic resonance imaging incorporating hyperpolarization techniques, such as PASADENA or DNP may be used in various app metabolomics, medical diagnosis and genetic research. | 09-16-2010 |
| 20100092391 | IMAGING AGENTS AND METHODS OF USE THEREOF - Compositions and methods useful in connection with magnetic resonance imaging are provided. Metabolites hyperpolarized by dynamic nuclear polarization are used as reporter molecules in nuclear magnetic resonance (“NMR”) spectroscopy to study metabolic pathways and diagnose disease states. The reporter molecules include hyperpolarized glutamine and hyperpolarized acetate. The invention includes the reporter molecules, compositions including the reporter molecules in pharmaceutically acceptable carriers, methods for studying metabolic pathways that include introducing one or more of the reporter molecules to a mammalian subject and imaging a target substance using NMR spectroscopy, and kits useful in studying metabolic pathways that incorporate one or more of the reporter molecules and instructions for their use. | 04-15-2010 |
| 20100087896 | APPARATUS AND METHOD FOR TREATING OBSTRUCTIVE SLEEP APNEA - The present invention describes an apparatus, a system and a method for the treatment of obstructive sleep apnea. The treatment involves monitoring the position of the tongue and/or the force exerted by the tongue and electrical stimulation of the hypoglossal nerve to move the tongue into an anterior position or to maintain the tongue in an anterior position | 04-08-2010 |
| 20090264732 | IMAGING AGENTS AND METHODS OF USE THEREOF - The present invention relates to compositions and methods useful in connection with magnetic resonance imaging. In various embodiments, the invention employs the PASADENA polarization technique to prepare contrast agents that target complementary molecules in the body and/or that are processed through predetermined, natural metabolic pathways. The invention includes methods of using the contrast agents and kits including the same. In one embodiment, a diagnostic and prognostic method relating to Alzheimer's disease is described. Further embodiments relate to medical devices including the contrast agents. | 10-22-2009 |
