| Hospital for Special Surgery Patent applications |
| Patent application number | Title | Published |
| 20110288199 | Fiber-Hydrogel Composite for Tissue Replacement - The present invention includes tailored fiber-reinforced hydrogel composites for implantation into a subject. The present invention also includes systems and methods for controlling the relative percent volume of the hydrogel and fibers, cross-linking, fiber orientation, weave and density, such that the material properties of the composite can be controlled and/or customized to match particular tissue types. The composites of the present invention are suitable for repairing or replacing musculoskeletal tissues and/or fibrocartilage, such as the meniscus, ligaments and tendons. | 11-24-2011 |
| 20110238016 | DRUG DELIVERY TO A JOINT - A drug delivery device may include a base to be percutaneously affixable in an attachment zone of a synovial joint and a sustained-release drug carrier coupled to the base. The drug delivery device may also include an access device to provide access to the attachment zone. The attachment zone may comprise a non-articulating portion of a bone and/or cartilage with the synovial joint and the drug carrier may elute the drug into the synovial fluid sufficient to sustain a therapeutically effective concentration of the drug in the synovial fluid for at least 8 hours. | 09-29-2011 |
| 20090068251 | METHODS AND COMPOSITIONS FOR PROMOTING WOUND HEALING - Provided herein are compositions and methods that inhibit expression of Adam12 gene products, such as ADAM12 mRNA and/or ADAM12 polypeptides, as a therapeutic approach for the treatment of, or promotion of healing of, wounds. | 03-12-2009 |