| HIROSHIMA UNIVERSITY Patent applications |
| Patent application number | Title | Published |
| 20120128645 | PROPHYLACTIC, AMELIORATING OR THERAPEUTIC AGENT FOR ORAL DISEASES - To provide a novel lactic acid bacterium strain having a broad antibacterial spectrum against bacteria that cause oral diseases, from which a fermented product having good flavor and being excellent in palatability can be produced, and a prophylactic, ameliorating or therapeutic agent for oral diseases using the same. | 05-24-2012 |
| 20120095379 | PELVIC BELT - A pelvic belt | 04-19-2012 |
| 20120064631 | METHOD FOR AMPLIFICATION AND HIGH-LEVEL EXPRESSION OF TARGET GENE IN MAMMALIAN CELL, AND KIT FOR ACHIEVING THE METHOD - The present invention provides novel means for amplifying a target gene outside a chromosome of the mammalian cell with a high probability in amplifying a target gene with use of IR/MAR plasmid, to further improve a high-level gene amplification system. The present invention is a method of amplifying a target gene outside a chromosome of a mammalian cell, and includes the step of transferring, concurrently to a mammalian cell, (i) a vector including (a) a mammalian replication initiation region functioning in a mammalian cell and (b) a nuclear matrix attachment region functioning in a mammalian cell, (ii) a target gene, and (iii) a polynucleotide including a telomere repetitive sequence. | 03-15-2012 |
| 20120046452 | ANTIBODY-MEDIATED REJECTION INHIBITOR - A purpose of the present disclosure to achieve transplantation from ABO-incompatible donors and inhibition of autoimmune disease, for example, without significantly impairing defense mechanisms. | 02-23-2012 |
| 20120046362 | ANTIVIRAL AGENT AND CLEANSING AGENT - It is an object to provide an antiviral agent that can be used for persons having sensitive skin or on the face, inactivates viruses such as a norovirus and an influenza virus, and is excellent in germicidal properties. Further provided is a cleansing agent that does not lead to environmental pollution since the cleansing agent is easily decomposed in the natural environment, scarcely causes eczema and allergic dermatitis since no germicidal agent is added, and has an antiviral performance. The antiviral agent containing a surface-active agent having a C18 unsaturated alkyl group as an active component. It is not always necessary to lather or rinse off with water like cleansing agents such as medicated soaps since the antiviral agent of the present invention at a very low concentration can inactivate the virus. | 02-23-2012 |
| 20120041228 | PHARMACEUTICAL COMPOSITION FOR AMELIORATING AND/OR PREVENTING LEPTIN RESISTANCE, AND USE THEREOF - The present invention provides a pharmaceutical composition for ameliorating and/or preventing leptin resistance. The pharmaceutical composition of the present invention contains flurbiprofen. | 02-16-2012 |
| 20120018675 | ALUMINUM OXIDE PHOSPHOR AND METHOD FOR PRODUCING THE SAME - The present invention provides an Al—C—O based phosphor using neither heavy metal nor rare metal and composed of elements with high environmental compatibility and excellent economic efficiency, wherein the wavelength of the peak intensity of the emission spectrum can be changed without changing the basic composition. An aluminum oxide phosphor which comprises aluminum (Al), carbon (C), and oxygen (O) respectively in an amount of 30 mol %| 01-26-2012 | |
| 20110311502 | AGENT FOR PREVENTION OR AMELIORATION OF OBESITY - To provide a pharmaceutical product or food which has an excellent fat-accumulation-inhibiting activity and/or fat-metabolism-improving activity and which is effective for inhibition or improvement of obesity, fatty liver, etc. | 12-22-2011 |
| 20110303910 | Field Effect Transistor - A heterocyclic compound represented by formula (1) and a field effect transistor having a semiconductor layer comprising the compound. (In the formula, X | 12-15-2011 |
| 20110300364 | POLYMER SHEET AND METHOD FOR PRODUCING SAME - A polymer sheet according to at least one embodiment of the present invention is a polymer sheet whose main component is oriented nanocrystals of a polymer, and which satisfies the following conditions (I), (II), and (III): (I) having a crystallinity of not less than 70%; (II) having a tensile strength at break of not less than 100 MPa and a tensile modulus of not less than 3 GPa; and (III) having an average thickness of not less than 0.15 mm. According to at least one embodiment of the present invention, it is possible to provide a polymer sheet excelling in properties such as mechanical strength, heat tolerance, and transparency, particularly a polymer sheet having excellent properties such as mechanical strength, heat tolerance, and transparency in general-purpose plastics such as polypropylene. | 12-08-2011 |
| 20110260108 | METHOD OF PRODUCING M-C-N-O BASED PHOSPHOR - A method of producing an M-C—N—O based phosphor with reduced non-uniform emission and improved color purity is provided. The method of producing an M-C—N—O based phosphor comprising a group IIIB element (M), carbon (C), nitrogen (N) and oxygen (O) comprises: heating a mixture comprising a group IIIB element-containing compound and a nitrogen-containing organic compound to form a pyrolysate; disintegrating the resulting pyrolysate-containing product; and firing the disintegrated product. | 10-27-2011 |
| 20110245187 | MESENCHYMAL CELL PROLIFERATION PROMOTER AND SKELETAL SYSTEM BIOMATERIAL - It is found that a SVVYGLR peptide (SEQ ID NO: 1) can promote proliferation of mesenchymal cells such as marrow-derived mesenchymal stem cells and dental pulp cells. A carbonate apatite-collagen sponge containing the SVVYGLR peptide (SEQ ID NO: 1) is useful as a biomaterial for the regeneration of bone marrow or dental pulp. It becomes possible to provide a skeletal system biomaterial which is capable of promoting the proliferation of the mesenchymal cells and is useful as artificial bone marrow or artificial dental pulp for repairing a defect in a bone marrow tissue or a dental pulp tissue. | 10-06-2011 |
| 20110204295 | Novel Heterocyclic Compound And Use Thereof - Disclosed are a heterocyclic compound characterized by being represented by formula (1), and a composition of the compound. Also disclosed is an organic electronic device using the compound. (In formula (1), X | 08-25-2011 |
| 20110172183 | METHOD OF FIXING ANTIBACTERIAL AGENT ARTICLE OBTAINED BY THE METHOD - An object of the present invention is to provide a method of fixing an antibacterial agent, by which method it is possible to impart articles of a wide range of materials with excellent antibacterial property and good persistence of antibacterial activity. Specifically, the method of fixing an antibacterial agent, comprises the steps of:
| 07-14-2011 |
| 20110156045 | CRYSTAL MANUFACTURING APPARATUS, SEMICONDUCTOR DEVICE MANUFACTURED USING THE SAME, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE USING THE SAME - A crystal manufacturing apparatus capable of manufacturing a crystal in a desired position on a substrate is provided. A spring has one end fixed to a mount and the other end coupled to a magnetic body. The magnetic body has one end coupled to the spring and the other end coupled to a piston. A coil is wound around the magnetic body and electrically connected between a power supply circuit and a ground node (GND). The piston has a linear member inserted in a cylinder. The cylinder has a hollow columnar shape and a small hole at a bottom surface. The cylinder holds a silicon melt. A substrate is supported by an XY stage to be opposed to the small hole of the cylinder. The power supply circuit passes pulse shaped current through the coil to move the piston in an up-down direction (DR | 06-30-2011 |
| 20110117103 | ANTI-SWEAT ANTIGEN MONOCLONAL ANTIBODY - [Object of the Invention] To provide an antibody that inhibits histamine releasing activity induced by an antigenic substance contained in sweat. | 05-19-2011 |
| 20110066048 | APPARATUS FOR EVALUATING VASCULAR ENDOTHELIAL FUNCTION - An apparatus for evaluating a vascular endothelial function, includes: a first cuff, to be wound around a first body part of a subject; a second cuff, to be wound around a second body part of the subject; a cuff pressure controller, configured to control a cuff pressure of each of the first and second cuffs, and configured to perform continuous pressure stimulation on the first body part of the subject for a time period by using the first cuff; a cuff pressure detector, configured to detect the cuff pressure of the second cuff from an output of a pressure sensor connected to the second cuff; a pulse wave detector, configured to detect, from the output of the pressure sensor, pulse waves before and after the continuous pressure stimulation is performed; and an analyzer, configured to evaluate the vascular endothelial function by comparing the pulse waves detected before and after the continuous pressure stimulation is performed. | 03-17-2011 |
| 20110033951 | ASSAY METHOD AND KIT FOR NUCLEIC ACID BINDING PROTEIN - An object of the present invention is to provide a method of detecting a nucleic acid binding protein and a method of screening for a binding inhibitor or promoter for a nucleic acid binding protein. According to the present invention, there is provided a method of detecting binding between a nucleic acid and a nucleic acid binding protein, comprising determining the degree of structural change in a nucleic acid complex having at least two nucleic acid duplex moieties. | 02-10-2011 |
| 20110027399 | Antiviral Agent and Antiviral Composition - An antiviral agent is provided which has an excellent effect on a non-enveloped virus and which is highly safe to the human body, and an antiviral composition which comprises the antiviral agent and which is useful for disinfection of the virus or prevention of infection of the virus. The antiviral agent comprises as an active ingredient an extract from a plant of the genus | 02-03-2011 |
| 20100324623 | TRANSCRANIAL ELECTRICAL STIMULATION DEVICE - A transcranial electrical stimulation device | 12-23-2010 |
| 20100317060 | METHOD FOR HIGHLY AMPLIFYING TARGET GENE IN MAMMALIAN CELL AND VECTOR THEREFOR - A vector of the present invention is a vector for amplifying a target gene in a mammalian cell, the vector including an amplification-activating fragment, which is a partial fragment of a mammalian replication initiation region and has a gene amplification activity site, and a mammalian nuclear matrix attachment region. In the case where the mammalian replication initiation region as described above derives from a c-myc locus, for example, the above-described partial fragment at least contains a duplex unwinding element and a topoisomerase II-binding domain. The vector as described above improves gene transfer efficiency and gene amplification efficiency compared with the existing high gene amplification systems. Thus, a method whereby a “high gene amplification system” developed by the inventors can amplify a target gene with better gene transfer efficiency and a vector to be used in this method are provided. | 12-16-2010 |
| 20100304467 | METHODS FOR PRODUCING HUMAN CERAMIDE USING YEAST TRANSFORMANTS - The present invention provides a method for producing human ceramide in a yeast cell. | 12-02-2010 |
| 20100289143 | METHOD FOR PRODUCING LOW-k FILM, SEMICONDUCTOR DEVICE, AND METHOD FOR MANUFACTURING THE SAME - Hydrophobicity of a low dielectric constant film comprising a porous silica film is improved by applying a raw material for forming a porous silica film onto a substrate, and performing vapor-phase transport treatment to expose the substrate to an atmosphere of organic amine vapor to which no water is added. Simultaneously, reduction in a dielectric constant, reduction in leakage current, and improvement in mechanical strength are attained by controlling a pore diameter in a predetermined range. | 11-18-2010 |
| 20100285177 | METHOD OF PRODUCING GABA-CONTAINING FERMENTED PRODUCT - It is intended to provide a method of efficiently producing a fermented fruit or vegetable product which contains GABA at an elevated concentration without damaging the inherent flavor of the fruit or the vegetable. A method of producing a fermented product containing γ-aminobutyric acid which is characterized by comprising fermenting a plant or its press juice by using | 11-11-2010 |
| 20100274538 | PROGRAM FOR OUTPUTTING STRESS-STRAIN EQUATION AND ITS DEVICE - There is provided a model that can evaluate properties of viscoelasticity and also rubber elasticity of an elastic material. A correlation equation between stress and strain that is calculated from: a correlation equation between stress, strain, elastic modulus and relaxation time, calculated based on a Maxwell model in which an elastic element and a viscous element are placed in series; and a correlation equation between strain and elastic modulus, including different moduli depending on properties, the correlation equation between stress and strain including different moduli depending on said properties as parameters is output as a stress-strain curve formula. There is one feature in finding a correlation between the strain and the elastic modulus, and this allows a large deformation behavior of an elastic material having properties of both rubber elasticity and viscoelasticity to be expressed with high quantitative characteristics on simulation. | 10-28-2010 |
| 20100267145 | IMMUNOCOMPETENT CELL HAVING ANTI-CD38 ANTIBODY ON ITS CELL SURFACE - An immunocompetent cell expressing an anti-CD38 antibody on its surface through genetic introduction of a DNA coding for part of the anti-CD38 antibody; and a method of producing an immunocompetent cell expressing the antibody on its cell surface, which includes amplifying a cDNA using the mRNA coding for part of the anti-CD38 antibody isolated from a hybridoma, inserting the amplified cDNA into a retroviral vector, transfecting the vector into a packaging cell to produce a packaging cell capable of producing an anti-CD38 antibody expressing-retroviral particle, and infecting a human immunocompetent cell with the retroviral particle released from the packaging cell. | 10-21-2010 |
| 20100240600 | Anti-Norovirus Agent and Composition Containing the Same - Provided is an anti-norovirus agent that has high norovirus-inactivating activity and is safe for the human body, and an anti-norovirus composition that contains the anti-norovirus agent and is useful for disinfection and infection control against the norovirus. The anti-norovirus agent includes, as an active ingredient, an extract from a plant of the genus | 09-23-2010 |
| 20100179976 | SEMICONDUCTOR DEVICE PERFORMING OPERATIONAL PROCESSING - A semiconductor device includes a decoder receiving first multiplier data of 3 bits indicating a multiplier to output a shift flag, an inversion flag, and an operation flag in accordance with Booth's algorithm, and a first partial product calculation unit receiving first multiplicand data of 2 bits indicating a multiplicand, a shift flag, an inversion flag, and an operation flag to select one of the higher order bit and lower order bit of the first multiplicand data based on the shift flag, invert or non-invert the selected bit based on the inversion flag, select one of the inverted or non-inverted data and data of a predetermined logic level based on the operation flag, and output the selected data as partial product data indicating the partial product of the first multiplier data and the first multiplicand data. | 07-15-2010 |
| 20100140683 | SILICON NITRIDE FILM AND NONVOLATILE SEMICONDUCTOR MEMORY DEVICE - Provided is a silicon nitride film which has an excellent charge storage capacity and thus is useful as a charge storage layer of a semiconductor memory device. The silicon nitride film having substantially uniform trap density in the film thickness direction has high charge storage performance. The silicon nitride film is formed by plasma CVD by using a plasma processing apparatus ( | 06-10-2010 |
| 20100137617 | METHOD FOR PRODUCING AROMATIC COMPOUND - Disclosed is a method for producing an aromatic compound represented by the general formula (2) below, which is characterized in that a compound represented by the general formula (1) below is reacted with a sulfur compound (at least one member selected from the group consisting of sulfur, hydrogen sulfide, metal hydrosulfides and metal sulfides) or a selenium compound. (In the formula (1), R | 06-03-2010 |
| 20100135898 | METHOD FOR PRODUCING METAL HYDRIDE - Disclosed is a method for producing a metal hydride, which enables to obtain a metal hydride from a metal imide or a metal amide. Specifically, in an air current containing a hydrogen gas having a hydrogen partial pressure of 0.1 MPa or greater, hydrogen is reacted with one or both of a metal imide and a metal amide, thereby producing a metal hydride. The metal constituting the metal amide and the metal imide is preferably lithium, sodium or potassium. | 06-03-2010 |
| 20100116913 | POWDER GREEN COMPACT, SINTERED COMPACT AND PROCESSES FOR PRODUCING THEM - A process for producing powder green compacts includes centrifugally compacting a slip containing a material powder, a binder resin and a dispersion medium in a mold, into a compact containing the material powder and the binder resin. A process for producing sintered compacts includes sintering the green compact. A powder green compact contains a material powder and a binder resin, the binder resin being present between particles of the material powder and binding the material particles. A sintered compact is obtained by sintering the green compact. | 05-13-2010 |
| 20100109508 | M-C-N-O BASED PHOSPHOR - M-C—N—O based phosphors having high emission intensity are provided without using heavy metals, rare metals, and special activator agents. Colors of the M-C—N—O based phosphors can be changed by adjusting a peak top of an emission spectrum. Highly environmentally-compatible polymer dispersions, inorganic EL devices, light emitting devices, fluorescent tubes, and the like are also provided, which use the M-C—N—O based phosphors. | 05-06-2010 |
| 20100086006 | TEMPERATURE MEASURING DEVICE, THERMAL TREATMENT DEVICE USING THE SAME, TEMPERATURE MEASURING METHOD - A temperature measuring apparatus, a temperature measuring method, and a thermal treatment apparatus which are suitable for temperature measurement of a substrate subjected to a rapid heating in thermal treatment are provided. The temperature measuring apparatus includes a light intensity measuring unit, a calculation unit, and a temperature output unit. In the light intensity measuring unit, an object to be heated having a uniquely defined correlation between temperature and refractive index is irradiated with a probe laser beam, and a light intensity property X is determined which represents a relationship between time and light intensity of a reflected light or a transmitted light occurring as a result of interference of the multiply-reflected probe laser beam within the object to be heated. In the calculation unit, which is for acquisition of a replicated object to be heated, a virtual object to be heated having equivalent dimensional, thermal, and optical characteristics to those of the object to be heated is subjected to a thermal incidence equivalent to the heating conditions of the object to be heated, a light intensity property of the virtual object to be heated being irradiated with a probe laser beam having an equivalent property to the above-mentioned probe laser beam is acquired, and a virtual object to be heated having a light intensity property Z, which is closest to the light intensity property X, is obtained as a replicated object to be heated. The temperature output unit acquires temperature of the object to be heated at a predetermined position thereon at a predetermined time on the basis of the replicated object to be heated. | 04-08-2010 |
| 20100030309 | EVOKED SPINAL CORD POTENTIAL MONITORING APPARATUS AND EVOKED SPINAL CORD POTENTIAL MONITORING SYSTEM - The evoked spinal cord potential monitoring apparatus of the present invention includes: a pair of electrodes | 02-04-2010 |
| 20100029905 | METHOD FOR PURIFYING PROTEIN - The present invention provides a method for purifying a protein, includes the step of: contacting a fusion protein of a first protein and a second protein with a bivalent cation-containing solution, the fusion protein being adsorbed to a silicon oxide-containing substance, the first protein being capable of binding to the silicon oxide-containing substance in a solution containing 0.1M sodium chloride. With this arrangement, it is possible to easily produce large quantity of proteins which are high in purity without sacrificing activity of the proteins. | 02-04-2010 |
| 20100001791 | CURRENT AMPLIFYING ELEMENT AND CURRENT AMPLIFICATION METHOD - A current amplifying element that operates at a higher speed than conventional semiconductor devices is provided. An input current flows through an input current path | 01-07-2010 |
| 20090325247 | METHODS FOR PRODUCING CERAMIDE USING TRANSFORMED YEAST - The present invention provides methods for producing human ceramide in a yeast cell. | 12-31-2009 |
| 20090305255 | Substrate Protein for M-Phase Kinase and use Thereof - An isolated protein of (a) a protein having an amino acid sequence of SEQ ID No. 2; (b) a protein having an amino acid sequence partially different from the amino acid sequence of SEQ ID No. 2 that is a substrate of M-period kinase and has nucleic acid-methylating activity suppressed by phosphorylation; (c) a protein having the amino acid sequence of SEQ ID No. 2 that is phosphorylated by M-period kinase; or (d) a protein having an amino acid sequence partially different from the amino acid sequence of SEQ ID No. 2 that is phosphorylated by M-period kinase. | 12-10-2009 |
| 20090298062 | METHOD FOR DETERMINATION OF THE LENGTH OF THE G-TAIL SEQUENCE AND KIT FOR THE METHOD - A method of measuring the length of a G tail sequence, characterized by hybridizing the G tail of an nondenatured chromosomal DNA in a sample with a labeled DNA probe having a sequence complementary to the telomere repeat sequence, measuring chemiluminescence from the hybridized DNA probe, and determining the length of the G tail sequence from the measured value, and a kit used for use in such a method. | 12-03-2009 |
| 20090291040 | ACTIVATION METHOD FOR LITHIUM HYDRIDE, AND HYDROGEN GENERATION METHOD - A lithium hydride activation method includes: a nitrification treatment process of reacting lithium hydride with a nitride and therefore forming a chemical compound layer stable to the nitride, on a surface of the lithium hydride; and a particle size reduction process of reducing a particle size of the lithium hydride provided with the chemical compound layer by a mechanical pulverization treatment after the nitrification treatment process is performed. A hydrogen generation method includes generating hydrogen by reacting ammonia with the lithium hydride activated by the activation method. | 11-26-2009 |
| 20090259131 | APPARATUS AND METHOD OF EVALUATING VASCULAR ENDOTHELIAL FUNCTION - An apparatus for evaluating a vascular endothelial function includes: a cuff, to be wound around a part of a body of a subject; a cuff pressure controller, configured to control a pressure of the cuff, and configured to apply continuous pressure stimulation; a cuff pressure detector, configured to detect the pressure of the cuff from output of a pressure sensor connected to the cuff; a pulse wave detector, configured to detect, from the output of the pressure sensor, pulse waves before and after the continuous pressure stimulation is applied; and an analyzer, configured to evaluate the vascular endothelial function by comparing the pulse waves detected before and after the continuous pressure stimulation is applied. | 10-15-2009 |
| 20090253636 | Novel Antifungal Agent - It is intended to provide a novel peptide which can exert higher antifungal effect also on a patient whose organ function is impaired with no side effect problems. The peptide comprises the following amino acid sequence: (1) SEQ ID NO:1: Lys-Arg-Leu-Phe-Arg-Arg-Trp-Gln-Trp-Arg-Tyr, (2) SEQ ID NO:2: Arg-Arg-Trp-Gln-Trp-Arg-Met-Lys-Lys-Tyr, (3) SEQ ID NO:3: Lys-Arg-Trp-Gln-TTp-Arg-Leu-Tyr, or (4) SEQ ID NO:4: Lys-Arg-Leu-Phe-Lys-Tyr, an antifungal agent comprising the peptide, a composition having a fungicidal and/or growth inhibitory action against fungus containing an effective amount of the peptide as an active ingredient, a medical apparatus/device which contains the peptide, whereby a fungicidal action is conferred, and a fungicidal and/or growth inhibiting method against fungus comprising administering the peptide and the like. | 10-08-2009 |
| 20080283763 | Method of Measuring Exposed Dose of Ionizing Radiation - A method of measuring an exposed dose of ionizing radiation, containing: (a) extracting proteins from a tissue or blood collected from a living body, and (b) determining the content of at least one of products of LyGDI protein degraded by caspase-1 and caspase-3 in the extracted proteins. | 11-20-2008 |