HALGEN CORPORATION Patent applications |
Patent application number | Title | Published |
20130130917 | METHOD FOR SPECIFIC ENRICHMENT OF NUCLEIC ACID SEQUENCES - The invention discloses a method for immobilizing nucleic acid probes to solid substrates. Also disclosed is a micro column format for specific sequence capture which enables efficient and convenient enrichment of target sequences from a complex source. The capture probes are immobilized onto microspheres or fibrous filter as the active component inside the column. The column format allows hybridization, post-hybridization wash and recovery of captured sequences all to take place in a simple device without sophisticated equipment. | 05-23-2013 |
20130005591 | METHOD FOR PARALLEL AMPLIFICATION OF NUCLEIC ACIDS - A new method that enables parallel amplification of nucleic sequences from a complex source is disclosed. The amplification is compartmentized into microdroplets by porous-walled hollow glass microspheres and subjected to PCR thermal cycling or isothermal amplification. The rigid wall of the glass microspheres allows very simple and conventional manipulation of the amplification products for downstream application such as sequencing or detection of copy number of specific sequences in a complex sample. | 01-03-2013 |