| GYROS PATENT AB Patent applications |
| Patent application number | Title | Published |
|---|
| 20120003682 | MICROFABRICATED APPARATUS FOR CELL BASED ASSAYS - Apparatus and methods are provided for performing cell growth and cell based assays in a liquid medium. The apparatus comprises a base plate supporting a plurality of micro-channel elements, each micro-channel element comprising a cell growth chamber, an inlet channel and an outlet channel, a cover plate positioned over the base plate to define the chambers and connecting channels. Means are incorporated in the cell growth chambers, for cell attachment and cell growth. In particular, the invention provides a rotatable disc microfabricated for performing cell growth and cell based assays. The apparatus and method can be used for the growth of cells and the detection and measurement of variety of biochemical processes and products using non-invasive techniques, that is techniques which do not compromise the integrity or viability of cells. | 01-05-2012 |
| 20110091904 | METHOD FOR DETERMINATION OF AFFINITY AND KINETIC CONSTANTS - The invention is related to a method for quantification of a first dissociation equilibrium constant K | 04-21-2011 |
| 20100091604 | MIXING METHOD - The present invention includes a method of mixing at least two aliquots in a microchannel structure ( | 04-15-2010 |
| 20100068099 | LID - An aspect of the present invention includes a microfluidic assembly comprising: a planar substrate, a least a first surface of which has at least one open microchannel structure, a lid forming sheet material attached with a first surface to said first surface of said planar substrate, said lid forming sheet material is covering at least a portion of said at least one microchannel structure, wherein said lid forming sheet material has a first region with a first rigidity and a second region with a second rigidity. Other aspects of the present invention are reflected in the detailed description, figures and claims. | 03-18-2010 |
| 20100044376 | METHOD OF BONDING A MICRIFLUIDIC DEVICE AND A MICROFLUIDIC DEVICE - An aspect of the present invention includes a microfluidic assembly comprising: a planar substrate, a least a first surface of which has at least one open microchannel structure, a lid-forming sheet material attached with a first surface to said first surface of said planar substrate, said lid-forming sheet material is covering at least a portion of said at least one microchannel structure, wherein said lid-forming sheet material is attached to said planar substrate with a bonding material comprising particles to control the spacing between said substrate and said lid-forming sheet material. Other aspects of the present invention are reflected in the detailed description, figures and claims. | 02-25-2010 |
| 20090308470 | SPINNER HOME SEQUENCE - The present invention relates to a method for determining the identity of a microfluidic device and a home position by means of a set of home position marks on the microfluidic device, which is of the type used in a microfluidic system. Said method comprises following phases: a microfluidic device scanning phase, wherein a microfluidic device is scanned for mark identifiers; a microfluidic device identifying phase, wherein at least one a characteristic feature of the set of home marks is/are determined and used for identifying the identity of the microfluidic device; a home position determining phase, wherein the home position is determined by the use of at least a subset of the home position marks identified during said previous phases. The present invention relates to a set of home marks, a microfluidic device carrying such a set of home marks, a microfluidic system, a computer program product and a computer program on a computer usable medium. | 12-17-2009 |
| 20090215196 | Sequential Method - A method for determination of an analyte in an original liquid sample by performing an inhibition affinity assay in a microchannel structure of a microfluidic device. The main characteristic feature is the steps of: (i) providing the microfluidic device in a form where the microchannel structure comprises a reaction microcavity which a) an inlet end, and b) contains a solid phase with binding sites (BS) for an analyte or an analyte-related entity, (ii) providing a liquid sample (1) containing the analyte or the analyte-related entity within the microchannel structure at the inlet end of the reaction microcavity, and flowing sample (1) through the reaction microcavity under conditions such that the analyte or the analyte-related entity is captured by BS leaving a portion of BS unoccupied (free BS), (iii) providing a liquid sample (2) which contains an analytically detectable analogue of the analyte or of the analyte-related entity, and flowing sample (2) through said reaction microcavity to capture the analogue by free BS, and (iv) measuring the amount of analyte analogue captured in step (iii) and relating this amount to the amount of analyte in an original sample. | 08-27-2009 |
| 20090120504 | Liquid plugs - A rotatable microfluidic device that comprises a hydrophilic microchannel structure in which there is a) an upstream microcavity I with a liquid outlet I, b) a microconduit I connected to liquid outlet I, and c) a capillary valve I associated with microconduit I. The inlet end of the microconduit is closer to the spin axis than the outlet end of the microconduit. The difference in radial distance between the inlet end and the outlet end of microconduit I is typically ≧5%, such as ≧10% or ≧100% or ≧500%, of the difference in radial distance between the uppermost part of the upstream microcavity and liquid outlet I. | 05-14-2009 |
| 20090111190 | Meander - A centrifugal based microfluidic device that comprises a microchannel structure in which there is a detection microcavity which in the upstream direction is attached to an inlet microconduit for transport of liquid (transport microconduit) to the detection microcavity and which is used for detecting the result of a reaction taking place in the detection microcavity or in a reaction microcavity positioned upstream of the detection microcavity. The detection microcavity comprises a detection microconduit having an inlet part and an outlet part and therebetween an upward or a downward meander. | 04-30-2009 |
| 20090010819 | VERSATILE FLOW PATH - A flow path comprising a reaction cavity in which there is a solid phase to which an affinity reactant I1 has been immobilized by the use of an immobilizing pair of reactive structures that comprises a) a plurality of functional equal structures RSsp on the solid phase, and b) a structure RSari on affinity reactant I1, where RSsp and RSari are mutually reactive with each other to the formation of a link structure that immobilizes affinity reactant I1 to the solid phase. The characteristic feature is that the solid phase comprises a plurality of structures that derive from RSsp but do not immobilize affinity reactant I1 to the solid phase. | 01-08-2009 |
| 20080286156 | Upward Microconduits - A microfluidic device comprising a hydrophilic microchannel structure in which there is a functional unit that comprises a microconduit which a) is intended for the transportation of liquid aliquots, and b) has an inlet end and an outlet end between which there is a capillary valve I. Microconduit I comprises an upwardly directed section that extends over a part of or over the full length of microconduit I. Capillary valve I is preferably placed in this section. | 11-20-2008 |
| 20080233594 | Method For Detecting An At Least Bivalent Analyte Using Two Affinity Reactants - A method for the determination of an analyte which is a) present in a liquid sample 1 suspected of containing the analyte, and b) at least bivalent with respect to simultaneous affinity binding of at least two binding structures BSs. The method comprises formation of an affinity complex that comprises the analyte and an affinity reactant 1 that is immobilized to a solid phase. The method comprises the steps of: (i) providing a microfluidic flow path that comprises a reaction cavity containing a solid phase to which affinity reactant 1 is immobilized, (ii) providing sample 1 upstream of the cavity and flowing it through the cavity for the formation of the affinity complex under flow conditions, (iii) measuring the amount of complex formed in the solid phase by a) incorporating an analytically detectable and soluble affinity reactant 2 that comprises a binding structure BS into the complex subsequent to step (ii), and b) measuring the amount of affinity reactant 2 incorporated. | 09-25-2008 |
| 20080226501 | Microfluidic Device With Finger Valves - A microfluidic device ( | 09-18-2008 |
| 20080206110 | SEPARATION STRUCTURE - A centrifugal-based microfluidic device ( | 08-28-2008 |
