| GUERBET Patent applications |
| Patent application number | Title | Published |
|---|
| 20120082624 | METHOD FOR PREPARING A PHARMACEUTICAL FORMULATION OF LANTHANIDE CHELATE IN POWDER FORM - The present invention relates to a method for preparing a pharmaceutical formulation of lanthanide chelate in powder form, this powder comprising a mol/mol excess of free chelate of between 0.002 and 0.4%, said method comprising the following successive steps:
| 04-05-2012 |
| 20120064003 | COMPLEX FOLATE-NOTA-Ga68 - The present invention concerns a Ga68 complex of formula FOLATE-(LINKER)i-NOTA-Ga | 03-15-2012 |
| 20120009124 | USE OF BUFFERS FOR RADIONUCLIDE COMPLEXATION - The present invention relates to a method for complexation of a chelate with a radionuclide, advantageously gallium, the complexation being carried out advantageously at ambient temperature without heating, by adding the radionuclide to the chelate in a buffer solution, the buffer of this solution comprising between two and five functions for coordination with the radionuclide, each coordination function being independently chosen from a carboxylic acid function and a hydroxyl function, on the condition that the buffer comprises at least one carboxylic acid function and at most two carboxylic acid functions. It also relates to the injectable solution obtained. | 01-12-2012 |
| 20110243859 | ENCAPSULATING SYSTEM FOR CEST IMAGING WITH CHELATE Q GREATER THAN OR EQUAL TO 2 - The present invention relates to the use of a CEST contrast agent in a method of CEST imaging, wherein the contrast agent is a composition comprising an encapsulating system ES encapsulating at least one CEST agent, wherein the at least one CEST agent is constituted of a monomeric chelate of a chelate of q≧2 type, or of a multimer of monomeric chelates of q≧2 type, and wherein said chelate is free inside the encapsulating system. | 10-06-2011 |
| 20110200533 | COMPOUNDS FOR THE DIAGNOSIS OF DISEASES ASSOCIATED WITH VCAM EXPRESSION - The present invention relates to a compound of the following general formula (I): | 08-18-2011 |
| 20100215586 | NOVEL METHOD FOR PREPARING NANOPARTICLES COVERED WITH A GEM-BISPHOSPHONATE STABILIZING LAYER COUPLED TO HYDROPHILIC BIODISTRIBUTION LIGANDS - A novel method for preparing nanoparticles for medical imaging, including a metal core, an organic stabilizing layer containing gem-bisphosphonate compounds and at least one hydrophilic biodistribution ligand. | 08-26-2010 |
| 20100111876 | USE OF METAL NANOPARTICLES IN THE DIAGNOSIS OF ALZHEIMER'S DISEASE - The invention relates to the use of metal nanoparticles for the preparation of a composition for diagnosing Alzheimer's disease by MRI. | 05-06-2010 |
| 20090299172 | Water Diffusion imaging and Uspio - The invention relates to a method of water diffusion imaging in magnetic resonance imaging in an area of diagnostic interest, characterized in that it comprises, in combination, the administration of a contrast product capable of generating a signal specifically in its specific location area, said location area being included in said area of interest, the application of a water diffusion imaging sequence to the whole area of interest, and the reading of the images in the area of interest, the specific signal due to the contrast product significantly and specifically modifying the signal in the specific location area relative to the signal of the whole area of interest. | 12-03-2009 |
| 20090214441 | Lipophilic Chelates and Their Use in Imaging - The invention relates to chelate compounds which can be used in MRI, the chelates being intended to be conveyed by lipophilic transporters, such as lipid nanoparticles or liposomes. The invention also relates to compounds comprising, in association, these chelates and these transporters, if appropriate connected via chemical bonding groups, and to their use in diagnostic imaging, it being possible for this association additionally to comprise biological targeting markers, denoted biovectors. | 08-27-2009 |
| 20090202435 | Diagnostic compounds for targeting a chemokine receptors - The present invention relates to a compound comprising, firstly a component for targeting at least one chemokine receptor and, secondly, a detection component capable of being identified by a medical imaging method. | 08-13-2009 |
| 20090169479 | Compounds Comprising Short Aminoalcohol Chains and Metal Complexes for Medical Imgaing - The present invention relates to a compound of formula (II) chosen from (IIa) and (IIb) or of formula (VI) chosen from (VIa) and (VIb) of following general formulae: | 07-02-2009 |
| 20090143471 | Process for the Atomization of Ioxilan - The invention relates to a process for the preparation of ioxilan of formula 5-[N-(2,3-dihydroxypropyl)acetamido]-2,4,6-triiodo-N-(2,3-dihydroxypropyl)-N′-(2-hydroxyethyl)isophthalamide by atomization and to the improved product thus obtained. This process makes it possible to avoid a process by crystallization and results in an active principle having an improved solubility. | 06-04-2009 |
