| Grindeks A Joint Stock Company Patent applications |
| Patent application number | Title | Published |
|---|
| 20100063292 | PROCESS FOR THE PREPARATION OF TRIFLUOROETHOXYTOLUENES. - The present invention relates to an process for the preparation 2,5-bis(2,2,2-trifluoroethoxy)toluene [II]. The compound 2,5-bis(2,2,2-trifluoroethoxy)toluene is useful as intermediate for pharmaceutical industry, especially useful as an intermediate for the preparation of Flecainide and pharmaceutically acceptable salts. | 03-11-2010 |
| 20100056794 | PROCESS FOR THE PREPARATION OF 2,5-BIS-(2,2,2-TRIFLUOROETHOXY)-N-(2-PIPERIDYL-METHYL)-BENZAMIDE AND SALTS THEREOF - Process for the preparation of 2,5-bis(2,2,2-trifluoroethoxy)-N-(2-piperidylmethyl)benzamide, its pharmaceutically acceptable salts and important intermediates thereof that involves 1,4-dihalotoluenes as starting material. The method involves a technique for preparing the starting material 2,5-bis(2,2,2-trifluoroethoxy)toluene in high yields by reacting 1,4-dibromotoluene with 2,2,2-trifluoroethanol in presence of a base and a copper-containing catalyst. | 03-04-2010 |
| 20100048915 | METHOD FOR PREPARING MEDETOMIDINE AND ITS SALTS. - The invention provides an improved, highly efficient method for preparing Medetomidine, and its salts, in particular its pharmaceutically acceptable salts. The method utilizes the high reactivity of halogenated imidazoles towards transmetalation with Grignard reagents and the subsequent reaction with 2,3-dimethylbenzaldehyde. | 02-25-2010 |
