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GRIFOLS,S.A.

GRIFOLS,S.A. Patent applications
Patent application numberTitlePublished
20110137283PROCESS FOR OBTAINING HIGH EFFICIENCY HUMAN ALBUMIN FOR USE IN DETOXIFICATION THERAPY - A process for purifying and collecting albumin from plasma and plasma fractions involves diafiltration of an albumin-containing plasma fraction; stabilizing the resulting albumin fraction with sodium chloride and an amino acid in the absence of any added fatty acid; pasteurizing the stabilized albumin fraction; and diafiltering the pasteurized fraction to remove, along other things, stabilizers. In one embodiment, the amino acid stabilizing agent is acetyl tryptophan. The resulting albumin has at least about 80% albumin binding capacity relative to natural plasma albumin, and is storage stable for about 30 months at 30° C.06-09-2011