GENESEQUE AS Patent applications |
Patent application number | Title | Published |
20140045703 | METHOD OF SEQUENCING - The present invention provides a method of sequencing a polynucleotide using a stepwise ligation and cleavage method in which two or more cleavage enzymes which are specific to two or more test probes are used sequentially to identify which test probe bound and hence the sequence of the target polynucleotide. In a preferred aspect the probes and/or bases used in the reaction are labelled, e.g. with a bead. | 02-13-2014 |
20140031239 | METHOD OF SEQUENCING - The present invention provides a method of sequencing a single polynucleotide in which the nucleotide base and/or probe which is incorporated during sequencing is labelled with a bead which is detected to identity the base and/or probe which has bound to the single polynucleotide. Particularly, the detection of the bead may be carried out using an apparatus comprising a surface provided with a means for detecting a bead e.g. with one or more light sensitive elements. | 01-30-2014 |
20120015833 | METHOD AND APPARATUS FOR DETECTING MOLECULES - The present invention is directed to a method of detecting a molecule attached to a surface comprising detecting a bead attached to said molecule. The method may be used for the detection of single molecules and the surface shape may be adapted to receive beads. The invention further encompasses an apparatus for detecting the presence of a molecule having a bead attached thereto comprising a surface which is provided with a means for detecting a bead wherein the shape of said surface is configured to receive and retain a bead. Kits comprising the apparatus are provided and a use of the apparatus for detecting a bead or a molecule attached thereto is contemplated. | 01-19-2012 |