| GE HEALTHCARE LIMITED Patent applications |
| Patent application number | Title | Published |
|---|
| 20120100072 | PET IMAGING OF FIBROGENESIS - The present invention relates to peptide compounds and their use for in vivo imaging using positron emission tomography (PET). More specifically, the invention relates to the use of such peptide-based compounds in a method for the in vivo imaging of liver fibrosis. | 04-26-2012 |
| 20120077967 | NOVEL TECHNETIUM AND RHENIUM COMPLEXES - Novel radioactive technetium and rhenium complexes comprising tripodal ligands are provided by the present invention. In particular, Tc(I) complexes are provided by the present invention. Novel ligands suitable for the formation of the technetium and rhenium complexes of the invention are also provided, as well as radiopharmaceutical compositions comprising said complexes, kits for their preparation. The invention also relates to the use of | 03-29-2012 |
| 20120004423 | SYNTHESIS OF OBTAINING MODIFIED POLYETHYLENE GLYCOL INTERMEDIATES - The present invention provides novel and more efficient synthesis's for obtaining an intermediate in the synthesis of obtaining a protecting group aminoxy PEG linker. | 01-05-2012 |
| 20110293518 | DIAGNOSIS OF WHIPLASH ASSOCIATED DISORDERS (WAD) BY USING PET WITH D-[METHYL-11C]-DEPRENYL (DDE) - Positron Emission Tomography (PET) tracers such as D-[methyl- | 12-01-2011 |
| 20110256055 | APPLICATION OF 99MTC PEPTIDE-BASED COMPOUND AS A BONE MARROW IMAGING AGENT - The present invention relates to methods and materials involved in using peptide-based compounds in bone marrow imaging. More specifically the invention relates to the use of 99mTc peptide-based compounds as targeting vectors that bind to receptors associated with angiogenesis, in particular integrin receptors, e.g. the αvβ3 integrin receptor. Such contrast agents may thus be used for diagnosis of haemolytic anaemia, myeloproliferative disorders, myelofibrosis, selection of biopsy sites, and early detection of skeletal metastatasis as well as detecting avascular necrosis of the femoral heads. | 10-20-2011 |
| 20110196149 | FLUORIDATION METHOD - A method for the fluoridation of an iodonium salt with a fluoride ion source which can be carried out in an aqueous reaction solvent. | 08-11-2011 |
| 20110129419 | IN VIVO IMAGING AGENTS - The present invention relates to the field of medical imaging, and in particular to imaging of disease states associated with the upregulation of the chemokine receptor 5 (CCR5). Imaging agents, precursors and methods are provided which are useful in imaging such disease states. | 06-02-2011 |
| 20110117012 | RADIOLABELED GALLIUM COMPLEXES, METHODS FOR SYNTHESIS AND USE FOR PET IMAGING OF EGFR EXPRESSION IN MALIGNANT TUMORS - The Invention relates to conjugates of formula (III) or (IIIa), or a salt thereof, their use as radiopharmaceuticals, processes for their preparation, and synthetic intermediates used in such processes. | 05-19-2011 |
| 20110070161 | ACTIVE ENANTIOMER - The present invention provides a PET tracer that has improved properties for imaging the peripheral benzodiazepine receptor (PBR) as compared with known such PET tracers. The present invention also provides a precursor compound useful in the preparation of the PET tracer of the invention and methods for the preparation of said precursor compound and said PET tracer. Also provided by the present invention is a radiopharmaceutical composition comprising the PET tracer of the invention. Methods for using the PET tracer and the radiopharmaceutical composition are also provided. | 03-24-2011 |
| 20110033387 | METHOD OF DETERMINATION OF PDH ACTIVITY AND IMAGING MEDIA FOR USE IN SAID METHOD - The invention relates to a method of determination of PDH activity by | 02-10-2011 |
| 20110028751 | PERFLUORO SULFONYL HALIDES AND RELATED SPECIES AS POLYMER SUPPORT MODIFIERS - Activated Supports, support-bound activators, strongly acidic supports, and silylating supports are provided; the activated support having the formula: | 02-03-2011 |
| 20110008261 | METHOD TO PRODUCE HYPERPOLARISED AMINO ACIDS AND AMINOSULPHONIC ACIDS - The invention relates to a dynamic nuclear polarisation (DNP) method for producing hyperpolarised amino acids and amino sulphonic acids and compositions for use in the method. As a sample, an ammonium salt of an amino acid, an ammonium salt of an aminosulphonic acid, a carboxylate salt of an amino acid, a sulphonate salt of an aminosulphonic acid or mixtures thereof is used. | 01-13-2011 |
| 20110008252 | STABALISED 99MTC COMPOSITIONS - The present invention relates to stabilised | 01-13-2011 |
| 20100234611 | Fluorination Process of Anilide Derivatives and Benzothiazole Fluorinate Derivatives as in VIVO Imaging Agents - The invention relates to a process for preparation of a compound of formula (I): R | 09-16-2010 |
| 20100178253 | PEPTIDE IMAGING AGENTS - The present invention relates to labelled cMet binding peptides suitable for optical imaging in vivo. The peptides are labelled with a benzopyrylium dye suitable for imaging in the red to near-infrared region. Also disclosed are pharmaceutical compositions and kits, as well as in vivo imaging methods, especially of use in the detection, staging, diagnosis, monitoring of disease progression or monitoring of treatment of colorectal cancer (CRC). | 07-15-2010 |
| 20100158804 | METHOD FOR THE USE OF [11C] CARBON MONOXIDE IN LABELING SYNTHESIS OF 11C-LABELLED ESTERS AND ACIDS BY SENSITIZED PHOTO-INDUCED FREE RADICAL CARBONYLATION - Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using alkyl/aryl iodides with alcohols or water treated by photosensitizers are provided. The resultant carbon-isotope labeled esters and acids, and pharmaceutical acceptable salts and solvates are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits and method for PET studies are also provided. | 06-24-2010 |
| 20100092387 | Novel Compound Having Affinity For Amyloid - A compound that has affinity with amyloid, exhibits sufficiently rapid clearance from normal tissues, and is suppressed in toxicity such as mutagenicity is provided, which is represented by the following formula (1): | 04-15-2010 |
| 20100040542 | CHELATOR CONJUGATES - The present invention relates to improved chelator conjugates with biological targeting molecules, suitable for forming metal complexes with radiometals. The radiometal complexes, especially with the radiometal | 02-18-2010 |
| 20090311178 | PYRROLINIDIUM DERIVATIVES AS M3 MUSCARINIC RECEPTORS - Compounds of formula (I) in salt or zwitterionic form, wherein R | 12-17-2009 |
| 20090155167 | AUTOMATED METHOD - The present invention provides an automated method for the preparation of | 06-18-2009 |
| 20080293969 | 18F-Labeled Daa Analogues and Method of Labeling These Analogues as Positron Emission Tomography (Pet) Tracers For Imaging Peripheral Benzodiazepine Receptors - Methods for selecting novel DAA analogues for a peripheral type benzodiazepine receptor were labeled with | 11-27-2008 |
| 20080279771 | Novel Imaging Agents for Cancer - A novel imaging agent is described which comprises a semaphorin moiety and an imaging moiety. The novel imaging agent of the invention may be used in the diagnostic imaging of cancer and in particular, for targeting angiogenesis or metaplasia. Further aspects of the present invention presented herein include a method for the preparation of the imaging agent, a pharmaceutical composition comprising the imaging agent of the invention and a kit for the preparation of said pharmaceutical. | 11-13-2008 |
| 20080274052 | RADIOFLORINATION METHODS - The present invention relates to methods and reagents for [ | 11-06-2008 |
| 20080242889 | METHOD FOR THE PRODUCTION OF PYRUVIC ACID - The invention relates to a method for the production of pyruvic acid, in particular pyruvic acid that is | 10-02-2008 |
| 20080226552 | Automated Radiolabelling Method - The present invention provides an automated method for the preparation of | 09-18-2008 |
