FUSO PHARMACEUTICAL INDUSTRIES, LTD. Patent applications |
Patent application number | Title | Published |
20160000418 | HEMOSTATIC AGENT APPLICATOR - Disclosed is a hemostatic agent applicator capable of effectively placing a fluid hemostatic agent on an incision surface. The present invention is a hemostatic agent applicator for use in disposing a fluid hemostatic agent, including a tool body in which a hollow part surrounded by a wall part is formed and which includes an open end part on a downstream side of the wall part, and an inlet provided to a portion of the wall part of the tool body to communicate with the hollow part. This hemostatic agent applicator is useful in medical settings relating to surgical procedures, particularly for surface bleeding of a liver and internal organ surgery such as a spleen and fibroid enucleation. An applicator further reduced in size can be applied not only in abdominal surgery, but in endoscopic surgery as well. | 01-07-2016 |
20150366851 | OSTEOPONTIN PRODUCTION INHIBITOR CONTAINING DICTYOPYRONE DERIVATIVE OR DIHYDRODICTYOPYRONE DERIVATIVE AS ACTIVE INGREDIENT - Disclosed herein is an osteopontin production inhibitor capable of preventing a disease resulting from increased production of osteopontin. | 12-24-2015 |
20150184230 | DETECTION OF BACTERIA BELONGING TO THE GENUS CAMPYLOBACTER BY TARGETING CYTOLETHAL DISTENDING TOXIN - An objective of the present invention is to provide the cytolethal distending toxin (CDT) of | 07-02-2015 |
20150147447 | METHOD FOR PRODUCING DETOXIFIED LIVER - The present invention has demonstrated that microorganisms present in a liver can be killed by washing the bile duct and the portal vein with hot water, and then disinfecting the liver using a chlorine-based disinfectant. It has also been demonstrated that sterilizing effects can be enhanced by freezing the liver after disinfection with a chlorine-based disinfectant. | 05-28-2015 |
20140370602 | TROPHECTODERMAL CELL-SPECIFIC GENE TRANSFER METHODS - The present inventors discovered that genes could be introduced specifically into trophectodermal cells with high efficiency, by infecting blastocysts with viral vectors carrying an arbitrary polynucleotide, or by using a nucleic acid transfection reagent in blastocysts, from which zona pellucida (extracellular matrix covering preimplantation early embryos to protect them from infection of viruses and the like) is removed. This method has no risk of infecting cells of the inner cell mass, which develops into a fetus in the future, with the introduced polynucleotide because the trophectoderm serves as a barrier. The present invention provides methods for introducing foreign genes into only placenta but not fetus, which enables rescue of genetically mutant animals from embryonic lethality due to placental abnormality and allows their birth. Furthermore, it is possible to analyze expression and effect of genes that regulate placental formation or placental function by using these methods. | 12-18-2014 |
20140335198 | STABLE BICARBONATE ION-CONTAINING DRUG SOLUTION - The invention relates to a stable bicarbonate ion-containing drug solution, particularly a bicarbonate-containing drug solution for dialysis in which the stability has been improved by the presence of a phosphate ion. Further, the invention relates to a drug solution for acute blood purification, particularly a dialysate and a substitution liquid for acute blood purification to be mixed before use containing the drug solution. Still further, the invention relates to a dialysate and a substitution liquid for acute blood purification to be mixed before use in which the formation of insoluble fine particles or precipitates is prevented for a long time after mixing and with which hypokalemeia and hypophosphatemia are not caused. | 11-13-2014 |
20140315322 | METHOD FOR MEASURING ACETIC ACID CONCENTRATION IN BLOOD PLASMA - The present invention relates to providing a simple and highly reproducible method for measuring the concentration of acetic acid in blood plasma by using a gas chromatography/mass spectrometry (GC/MS), and more specifically relates to a method for measuring the concentration of acetic acid in blood plasma by using a gas chromatography/mass spectrometry (GC/MS), which comprises extracting acetic acid in blood plasma with methyl-tert-butyl ether (MTBE). | 10-23-2014 |
20130230918 | NOVEL COLLECTIN - Novel collectin related molecules i.e., a novel collectin gene comprising a nucleotide sequence set out in SEQ ID NO: 1, and a novel collectin comprising an amino acid sequence set out in SEQ ID NO: 2, which are expected to exhibit anti-bacterial, anti-viral activity or the like especially in human body, and methods in which these molecules are used are provided. | 09-05-2013 |
20130183764 | HIGH PURITY HEPARIN AND PRODUCTION METHOD THEREFOR - The present invention provides a high purity heparin useful to be a pharmaceutical product, cosmetics, research reagent, or the like, and a method for producing the same, more specifically, a heparin which does not substantially contain a nitrous acid degradation-resistant impurity and a method for producing a heparin, comprising mixing an aqueous solution of 5 to 30% by weight of the heparin with ethanol having an amount (volume) 0.2 to 1 times the amount (volume) of the aqueous heparin solution to obtain a colloidal precipitate of heparin. | 07-18-2013 |
20130150565 | NOVEL COLLECTIN - Provided are isolated collectin (CL-L2s) genes including a base sequence set out in SEQ ID NO: 1, 3, 5, 7, 9, 12, 36, 38 or 40 relating to a novel collectin which are expected to exhibit an antibacterial activity, an antiviral activity and the like particularly in a human body; and isolated collectin proteins including an amino acid sequence set out in SEQ ID NO: 2, 4, 6, 8, 10, 13, 37, 39 or 41 and derivatives and fragments thereof. | 06-13-2013 |
20130123313 | BENZOFURANONE COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME - Provided is a novel compound having an effective anti-cancer activity. | 05-16-2013 |
20130065817 | POLYPEPTIDE ACTING TO ENHANCE ISCHEMIC DISEASES - Disclosed is a polypeptide of use in the development of reagents or medicines favourable to application for prevention or treatment of ischemic disorders such as conditions caused by ateriosclerosis. The polypeptide has at least one part containing an amino acid of sequence ID 1, and also enhances expression levels of the amino acid in mammalian blood vessels removed from ischemic conditions by means of blood reperfusion. | 03-14-2013 |
20130025058 | RESPIRATORY TRACT WIDENING TOOL AND RESPIRATORY TRACT WIDENING UNIT PROVIDED THEREWITH - A respiratory tract widening tool capable of reliably managing a respiratory tract in a supine posture and freely changing the posture, and a respiratory tract widening unit provided therewith are provided. | 01-31-2013 |
20120015400 | HCL-K1 Polypeptide Which Offers Collectin Activity - Disclosed is the novel hCL-K1 polypeptide which offers collectin activity. This polypeptide consists of consecutive 271 amino acids set out in SEQ ID NO: 2 and does not bind to both maltose and N-acetylgalactosamine. | 01-19-2012 |
20110224154 | PEPTIDE DERIVATIVE AND COMPOSITION FOR PROMOTING TEAR SECRETION COMPRISING THE SAME - A composition for promoting lacrimal secretion which can be used safely and effectively in the lacrimal secretion promoting therapy, not in the conventional supplemental therapy of lacrimal fluid components is provided. The composition for promoting lacrimal secretion comprising a peptide derivative represented by the formula (I): | 09-15-2011 |
20110065177 | Novel Collectin - Novel collectin related molecules i.e., a novel collectin gene comprising a nucleotide sequence set out in SEQ ID NO: 1, and a novel collectin comprising an amino acid sequence set out in SEQ ID NO: 2, which are expected to exhibit anti-bacterial, anti-viral activity or the like especially in human body, and methods in which these molecules are used are provided. | 03-17-2011 |
20110008431 | THERAPEUTIC TABLET FOR POSTHERPETIC NEURALGIA AND METHOD OF TREATING POSTHERPETIC NEURALGIA - The present invention provides a tablet for treating postherpetic neuralgia and a method of treating postherpetic neuralgia with the use of the tablet. The therapeutic tablet for postherpetic neuralgia according to the present invention is characterized in comprising buprenorphine hydrochloride, having a double layer structure consisting of a quick-release layer and a sustained-release layer, wherein the tablet is adhesive to the oral mucosa. | 01-13-2011 |
20100206753 | STABLE BICARBONATE ION-CONTAINING DRUG SOLUTION - The invention relates to a stable bicarbonate ion-containing drug solution, particularly a bicarbonate-containing drug solution for dialysis in which the stability has been improved by the presence of a phosphate ion. Further, the invention relates to a drug solution for acute blood purification, particularly a dialysate and a substitution liquid for acute blood purification to be mixed before use containing the drug solution. Still further, the invention relates to a dialysate and a substitution liquid for acute blood purification to be mixed before use in which the formation of insoluble fine particles or precipitates is prevented for a long time after mixing and with which hypokalemeia and hypophosphatemia are not caused. | 08-19-2010 |
20100113750 | NOVEL SCAVENGER RECEPTOR - Novel scavenger receptors having an SR structure and a collectin-like structure are provided, which can be utilized in the elucidation of mechanisms of macrophage and basic immunity; in the elucidation of mechanisms of the development of a wide variety of diseases such as arteriosclerosis, diabetic complications and Alzheimer's disease, hyper β-lipoproteinemia, hypercholesterolemia, hypertriglyceridemia. hypo α-lipoproteinemia, transplantation, atherectomy, post angiogenic restenosis, bacterial infections; in the diagnostic, prophylactic and therapeutic methods thereof; and in the development of reagents and drugs for the same. The novel scavenger receptors include proteins comprising an amino acid sequence set out in SEQ ID NO: | 05-06-2010 |
20100113749 | NOVEL SCAVENGER RECEPTOR - Novel scavenger receptors having an SR structure and a collectin-like structure are provided, which can be utilized in the elucidation of mechanisms of macrophage and basic immunity; in the elucidation of mechanisms of the development of a wide variety of diseases such as arteriosclerosis, diabetic complications and Alzheimer's disease, hyper β-lipoproteinemia, hypercholesterolemia, hypertriglyceridemia, hypo α-lipoproteinemia, transplantation, atherectomy, post angiogenic restenosis, bacterial infections; in the diagnostic, prophylactic and therapeutic methods thereof; and in the development of reagents and drugs for the same. The novel scavenger receptors include proteins comprising an amino acid sequence set out in SEQ ID NO: 2, 4 or 24 or proteins having equivalent properties to the same, or derivatives or fragments thereof as well as isolated polynucleotides comprising a nucleotide sequence encoding these proteins, and related molecules such as antibodies, antagonists and the like. Also disclosed are methods for the treatment using the same. | 05-06-2010 |
20100098757 | PROCESS FOR PRODUCTION OF BUPRENORPHINE PHARMACEUTICAL PREPARATION TO BE APPLIED TO MOUTH MUCOSA - The objective of the present invention is to provide a process for producing a buprenorphine pharmaceutical preparation to be applied to mouth mucosa. The process according to the present invention for producing a buprenorphine pharmaceutical preparation to be applied to mouth mucosa includes steps of: preparing a granule for an immediate-release layer containing a buprenorphine hydrochloride crystal having 90% cumulative diameter of 200 μm or less; preparing a granule for a sustained-release layer containing a buprenorphine hydrochloride crystal having 90% cumulative diameter of 250 μm or less; and tabletting the granule for the immediate-release layer and the granule for the sustained-release layer into a two-layer tablet. | 04-22-2010 |
20090305341 | HCL-K1 Polypeptide Which Offers Collectin Activity - Disclosed is the novel hCL-K1 polypeptide which offer collectin activity. This polypeptide consists of consecutive 271 amino acids set out in SEQ ID NO: 2 and does not bind to both maltose and N-acetylgalactosamine. | 12-10-2009 |
20090275740 | NOVEL COLLECTIN - Provided are isolated collectin (CL-L2s) genes including a base sequence set out in SEQ ID NO: 1, 3, 5, 7, 9, 12, 36, 38 or 40 relating to a novel collectin which are expected to exhibit an antibacterial activity, an antiviral activity and the like particularly in a human body; and isolated collectin proteins including an amino acid sequence set out in SEQ ID NO: 2, 4, 6, 8, 10, 13, 37, 39 or 41 and derivatives and fragments thereof. | 11-05-2009 |
20090048165 | ANTI-HIV AGENT - Disclosed are anti-HIV agents which comprise a mannose binding protein (MBP) as an active component and are useful for effectively inhibiting progress of diseases state in and useful in therapy for individuals infected with human immunodeficiency virus (HIV). Also disclosed are a method for evaluating an anti-HIV activity of MBP comprising the step of culturing HIV infected cells under the presence of MBP. | 02-19-2009 |
20080274484 | Method for Diagnosing Renal Disorder, Hemolytic Uremic Syndrome and Enterohemorrhagic Infectious Disease Caused by Escherichia Coli - Methods for diagnosing renal disorder, hemolytic uremic syndrome and enterohemorrhagic | 11-06-2008 |
20080274483 | Method for Diagnosing Renal Disorder, Hemolytic Uremic Syndrome and Enterohemorrhagic Infectious Disease Caused by Escherichia Coli - Methods for diagnosing renal disorder, hemolytic uremic syndrome and enterohemorrhagic | 11-06-2008 |