FUNDACAO OSWALDO CRUZ Patent applications |
Patent application number | Title | Published |
20150057174 | DIFFERENTIAL DIAGNOSTIC METHOD AND KIT FOR INFECTIOUS AND PARASITIC DISEASES, USING FLOW CYTOMETRY - The present invention relates to a differential diagnostic method using flow cytometry, performed by means of differential fluorescent marking of biological agents, such as cells and pathogens of interest, with fluorescent substances. The diagnostic method generally consists in performing fluorescent marking of biological agents with gradual concentrations of fluorescent substances, and in analysing the reactivity profile of IgG1 to the biological agents. The present invention further relates to a diagnostic kit. | 02-26-2015 |
20140246812 | PROCESS FOR PRODUCING POLYMERIC STRUCTURES THAT HAVE ACTIVATED SURFACES AND ACTIVATED POLYMERIC STRUCTURES - The present invention relates to a process for producing polymeric structures that have activated surfaces. The process proved to be simple, quick, with high production capacity and low operating costs. The process occurs by depositing a polymer solution, which is assisted by a high electric field, on a conductive liquid surface to produce particles and/or filaments that have an activated surface. More particularly, the process of the present invention has the ability to produce particles and/or filaments that have chemically activated surfaces, in a single process. | 09-04-2014 |
20130104674 | AQUATIC MACROINVERTEBRATE SUBSAMPLING EQUIPMENT | 05-02-2013 |
20130085159 | COMPOUNDS DERIVED FROM ARTESUNATE, PREPARATION PROCESS, PHARMACEUTICAL COMPOSITION AND USE OF THE RESPECTIVE MEDICINE - The present invention refers to new compounds represented by the general formula (I) where X is represented by the general formula (II) and Y is represented by the general formula (III). The relation X to Y may vary from 1:1 to 1:7. The radicals R | 04-04-2013 |
20120308603 | DNA VACCINE AGAINST VIRUS OF YELLOW FEVER - The present invention relates to vaccines of DNA that code for specific viral sequences. The DNA vaccines against yellow fever according to the invention are based on the sequence that codes for the yellow fever virus envelope protein (p/YFE). Besides the wild p/YFE construct, sequence E was also fused with the sequence that codes for the human lysosome-associated membrane protein (h-LAMP), generating the construct (pL/YFE). The results of the invention are considered to be very promising, since both constructs can induce T-cell response against the same epitopes induced by the 17DD vaccine, and the pL/YFE construct can also induce a satisfactory concentration of neutralising antibodies. The pL/YFE vector was inoculated in mice, before intracerebral challenge with the virus of yellow fever. Surprisingly, 100% of the mice immunised with pL/YFE survived the challenge. | 12-06-2012 |
20120251570 | METHOD, KIT, PLASMID AND COMPOSITION FOR INDUCING AN IMMUNE RESPONSE TO DENGUE VIRUS, ON THE BASIS OF DNA AND CHIMERIC VIRUS VACCINES - The present invention relates to a method for inducing an immune response to the dengue virus, on the basis of DNA and 17D chimeric virus vaccines in combined or co-administered immunisation. The scope of the present invention also includes DNA vaccines against the four serotypes of the dengue virus, produced by forming, from each viral serotype of the dengue virus (DENV1-4), various recombinant plasmids that contain the gene that codes for the E protein, or that contain only the sequence that corresponds to the domain III of this protein. The invention also provides a vaccine composition consisting of (a) DNA vaccines against the four serotypes of the dengue virus; (b) chimeric viruses comprising the modified yellow fever vaccination virus 17D; and (c) a pharmaceutically acceptable carrier, all of which are covered by the scope of the invention. | 10-04-2012 |
20120195907 | MONOCLONAL ANTIBODIES AGAINST THE PBP2-A PROTEIN AND HOMOLOGOUS SEQUENCES FOR THE TREATMENT OF INFECTIONS BY AND IMMUNODIAGNOSTICS OF BACTERIA OF THE FIRMICUTES PHYLUM - The present invention relates to monoclonal antibodies capable of recognising and binding to the PBP2-a protein and to other proteins having sequences homologous to PBP2-a, including pathogenic species such as the methyciline-resistant | 08-02-2012 |
20110220672 | ALTERNATIVE FEEDING DEVICE FOR INFANTS AT RISK - The present request is for a utility model referring to an easy to use object, most appropriate for use as an alternative for feeding premature newborns, for phonotherapy and could be used for other people. The device basically consists of a cup with a raised colored graded scale placed on the cup side easy visualization, a flow reducer composed of folds and a round spout formed from the actual cup rim facilitating contact with the mouth of the baby, a lid of the cup rim where it will fit using pressure avoiding food contamination. | 09-15-2011 |
20110045016 | UTILIZATION OF RECOMBINANT INFLUENZA VIRUSES AND MODIFIED VACCINIA ANKARA VIRUS (MVA) WITH GENES THAT ENCODE FOR THE TOXOPLASMA GONDII SAG1 AND SAG2 SURFACE PROTEINS, AS VACCINES AGAINST TOXOPLASMOSIS - The present invention concerns to recombinant influenza viruses and modified Vaccinia Ankara viruses (MVA), and to a process for construction of recombinant influenza viruses and modified vaccinia Ankara viruses (MVA) with genes that encode for the | 02-24-2011 |
20100045677 | SYSTEM AND METHOD FOR CREATION OF PERSPECTIVE IMAGES GENERATED BY A NEGATIVE EXPONENTIAL ALGORITHM - A system for creation of perspective images of the present invention includes: A new method for transforming three-dimensional (3D) world coordinates into two-dimensional (2D) screen coordinates using a negative exponential algorithm, instead of the classical projection algorithms that have the distance āzā to the observer in the denominator (division algorithms); A new method for generating realistic perspective images of objects located at any distance from the observer (positive, negative or zero distances) that does not need any correction for zero or negative distances; The demonstration of practical use of the invention by computer graphics programs that generates and displays perspective images based on this exponential algorithm. | 02-25-2010 |