| FUDAN UNIVERSITY Patent applications |
| Patent application number | Title | Published |
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| 20120122902 | PYRIMIDINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF - A pyrimidine derivative and the preparation method and usethereof. The said pyrimidine derivative is a diaryl pyrimidine derivative or a diaryl benzo pyrimidine derivative which has the structure shown as the Formula I and IV. | 05-17-2012 |
| 20120119268 | Mixed Junction Source/Drain Field-Effect-Transistor and Method of Making the Same - The present invention is related to microelectronic technologies, and discloses specifically a mixed junction source/drain field-effect-transistor and methods of making the same. The field-effect-transistor with mixed junction source/drain comprises a semiconductor substrate, a gate structure, sidewalls, and source and drain regions having mixed junction structures, which are combinations of Schottky and P-N junctions. Compared with Schottky junction field-effect-transistors, the mixed junction source/drain field-effect-transistor described in the present invention has the characteristics of relatively low source/drain leakage. At the same time, this field-effect-transistor has lower source/drain series resistances than that associated with P-N junction field-effect-transistors. | 05-17-2012 |
| 20120081155 | Dual-Mode Voltage Controlled Oscillator, Frequency Synthesizer and Wireless Receiving Device - The invention provides a dual-mode voltage-controlled oscillator (DMVCO), a frequency synthesizer and a wireless receiving device, and pertains to the technical field of integrated circuit of radio frequency wireless receiver. The DMVCO and the frequency synthesizer can operate in a wideband mode and a quadrature mode. When operating in the quadrature mode, a quadrature signal is provided for a Single Sideband Mixer of the frequency synthesizer by a quadrature coupling of a first voltage-controlled oscillator unit and a second voltage-controlled oscillator unit in the DMVCO in the overlapped frequency band so that the frequency synthesizer can cover a higher output frequency band. Therefore, the tuning range of the DMVCO of the invention is wide, and the frequency synthesizer using the DMVCO is low in power consumption, simple in structure and has good frequency spur performance. | 04-05-2012 |
| 20120065135 | Genetically Modified TFPI And Method Of Making The Same - The present invention provides long half life genetically modified TFPI sequences (LTFPI) for anticoagulation. On the genetically modified TFPI sequence, the lysine at the carboxy-terminal sites 241, 254, 260 and 261 are replaced by alanin and the amino acid asparagine at glycosylation sites 117, 167, 228 and the amino acids serine and threonine at glycosylation sites 174 and 175 are substitutionally mutated. The present invention also provides methods of making the LTFPI through high efficient LTFPI expression from yeast production system. | 03-15-2012 |
| 20110316070 | CHARGE TRAPPING NON-VOLATILE SEMICONDUCTOR MEMORY DEVICE AND METHOD OF MAKING - The present invention provides a charge trapping non-volatile semiconductor memory device and a method of making the device. The charge trapping non-volatile semiconductor memory device comprises a semiconductor substrate, a source region, a drain region, and, consecutively formed over the semiconductor substrate, a channel insulation layer, a charge trapping layer, a blocking insulation layer, and a gate electrode. The drain region includes a P-N junction, and the source region includes a metal-semiconductor junction formed between the semiconductor substrate and a metal including titanium, cobalt, nickel, platinum or one of their various combinations. The charge trapping non-volatile semiconductor memory device according to the present disclosure has low programming voltage, fast programming speed, low energy consumption, and relatively high device reliability. | 12-29-2011 |
| 20110124521 | Use of MiR-26 Family as a Predictive Marker for Hepatocellular Carcinoma and Responsiveness to Therapy - It is disclosed herein that expression of microRNA-26 is decreased in hepatocellular (HCC) tumor tissue relative to non-cancerous tissue, and that a low level of microRNA-26 is associated with a poor clinical outcome. It is also disclosed herein that a low expression level of microRNA-26 is correlated with a favorable response to interferon (IFN)-α therapy in HCC patients. Thus, provided herein is a method of predicting the clinical outcome of a patient diagnosed with HCC comprising detecting the level of microRNA-26 expression in a sample obtained from the patient. Also provided is a method of selecting a patient diagnosed with HCC as a candidate for IFN-α therapy, comprising detecting the level of microRNA-26 expression in a sample obtained from the patient. A method of identifying therapeutic agents for the treatment of HCC, comprising screening candidate agents in vitro to select an agent that increases expression of microRNA-26 in HCC cells are also provided. Further provided are methods of treating a patient diagnosed with HCC and expressing a low level of miR-26, wherein treatment comprises IFN-α therapy. | 05-26-2011 |
| 20110002905 | COMPOSITIONS OF FAT-SOLUBLE ACTIVE INGREDIENTS CONTAINING PROTEIN-POLYSACCHARIDE CONJUGATES - The present invention relates to compositions containing one or more proteins, one or more polysaccharides and one or more fat-soluble active ingredients and their use for the enrichment, fortification and/or coloration of food beverages, animal feed and/or cosmetics. | 01-06-2011 |
| 20100055135 | ENHANCIN OF HEPATITIS B VIRUS VACCINE AND ITS GENE - This invention relates to a HB vaccine enhancing protein, its gene, gene engineering method for expressing this protein, and the application of this method. The cDNA of this protein, which is screened out from human liver cDNA library, is sequenced and then cloned into prokaryotic or eukaryotic (animal or plant) cell for expression of protein coded by the cDNA (for example, cloning into prokaryotic expression carrier and expression in | 03-04-2010 |
| 20090087421 | Novel Recombinant Staphylokinase Derivatives and the Preparations and Applications thereof - The present invention relates to the biotechnology field, more particularly, to novel recombinant staphylokinase (RGD/KGD-Sak) derivatives and the preparation the thereof. The derivatives, have a low polymerizing ability, low immunogenicity and a bifunctionality of thrombolytics and anticoagulant. Based on the line, structural analysis of the monomer and dimer of recombinant staphylokinases and their biochemical properties, we designed two novel bifunctional staphylokinase molecular structures. Mutant genes were constructed by PCR site-directed mutagenesis which were then recombined with a prokaryotic vector and used to transform | 04-02-2009 |
