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FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBER

FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBER Patent applications
Patent application numberTitlePublished
20100048415METHOD FOR THE DETECTION OF INTERFERON-ASSOCIATED ANGIOSTATIC TUMORSTAGES IN COLORECTAL CARCINOMA - The present invention is directed to a microarray for the detection of an angiostatic tumor stage/tumor area of colorectal carcinoma in a patient, wherein the microarray comprises gene probes capable of specifically hybridizing to predefined nucleic acids. The invention is further directed to an inhibitor or modulator of one or more of these nucleic acids, as well as to a pharmaceutical composition, comprising those inhibitors or modulators. In a further aspect, the present invention is directed to an ex vivo method for the diagnosis of an angiostatic tumor stage/tumor area in a patient suffering from a colorectal carcinoma. In a further aspect the invention is directed to predict the response of patients with colorectal carcinoma but also other diseases to therapy.02-25-2010