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FREUND CORPORATION

FREUND CORPORATION Patent applications
Patent application numberTitlePublished
20100247665Spherical Particle and Method for Producing the Same - A spherical particle of the present invention contains a sugar alcohol and a crystalline cellulose and/or powdered cellulose, wherein the mass ratio between the sugar alcohol and the crystalline cellulose and/or powdered cellulose is within a range from 50:50 to 90:10, the particle size is within a range from 75 to 250 μm, the sphericity is not less than 0.8, and the bulk density is not less than 0.6 g/ml. Further, a method for producing the spherical particle of the present invention includes a granulation step of rolling a sugar alcohol having an average particle size of not more than 40 μm and a crystalline cellulose and/or powdered cellulose having an average particle size of not more than 50 μm while spraying a liquid thereon.09-30-2010
20100047323CHITOSAN SOLUTION AND MEDICAL PREPARATION WITH CHITOSAN COATING FORMED FROM THE SOLUTION - A chitosan coating solution safe for oral administration, a water resistant chitosan coating film with reduced content of residual organic acid, and a coated medical preparation having the coating film are described. The preparation method includes incorporating a glycerin fatty acid ester into an aqueous chitosan solution prepared through dissolution with a volatile organic acid. The chitosan coating film is obtained by drying and solidifying the solution through film coating. The organic acid used in the dissolution remains in the coating film only minutely and the film is water resistant. When the chitosan coating solution (containing a glycerin fatty acid ester, and prepared through dissolution with a volatile organic acid) is coated, a film is formed therewith, and the organic acid volatilizes simultaneously, producing a chitosan water resistant coating film. Forming a known enteric coating film in combination with the outer coating film allows application to large-intestine drug delivery.02-25-2010
20100034956Highly Water Dispersible Powder and Production Method Thereof - Provided is a highly water dispersible powder which exhibits a high water dispersibility in spite of the inclusion of a poorly water soluble component, and maintains the high water dispersibility stably over time.02-11-2010