| FREIE UNIVERSITÄT BERLIN Patent applications |
| Patent application number | Title | Published |
|---|
| 20110117009 | DRUG CONJUGATES WITH POLYGLYCEROLS - The present invention relates to a drug polymer conjugate comprising a pharmaceutically active compound and a dendritic polyglycerol, as well as to a drug polymer conjugate comprising a pharmaceutically and/or diagnostically active compound bound to a dendritic polyglycerol core having a polyethylene glycol shell. | 05-19-2011 |
| 20110045568 | METHOD FOR RESTORING BMP-RECEPTOR SIGNALING IN A CELL - The invention relates to a method for restoring BMP-receptor signaling in a cell. According to the invention, the activity of the protein cGKI is increased in a cell. Furthermore, the invention relates to the use of cGKI for the treatment of a disease selected from the group consisting of pulmonary artery hypertension (PAH), cancer, fibrosis, bone diseases, and neurodegenerative diseases, and the use of cGKI for manufacturing a pharmaceutical composition for the treatment of said diseases, the use of a BMP receptor for screening for compounds having cGKI activity, the use of cGKI for screening for receptors associated with it, and the use of cGKI for the transcriptional activation of genes containing a BMP response element. | 02-24-2011 |
| 20100143880 | ANALYSIS METHOD FOR DETERMINING A FUNCTIONAL PARAMETER OF AN ORGAN USING PREFERABLY AN AQUEOUS 13C-METHACETIN SOLUTION - The invention relates to an analysis method for determining a functional parameter of an organ of a human or animal individual by measuring the | 06-10-2010 |
| 20100115666 | Transcriptional Repressors of Cytokinin Signaling and Their Use - The invention relates to fusion proteins capable of acting as transcriptional repressors of cytokinin signaling, to polynucleotides encoding these fusion proteins, to vectors and cells comprising these polynucleotides, and to transgenic plants and parts thereof comprising these polynucleotides, vectors, and cells. | 05-06-2010 |
| 20100081773 | DIVALENT METAL-ION LOADED NANO-TRANSPORT SYSTEM HAVING A DENDRITIC ARCHITECTURE USEFUL FOR THERAPY - Described is the use of a nanocarrier having a dendritic structure which is composed of a dendritic core and at least one shell for the non-covalent encapsulation and/or transport of divalent metal-ions, preferably Cu-ions or Zn(II) -ions. Also described is a pharmaceutical composition containing such nanocarrier complexed divalent metal-ions in a non-covalent encapsulated form. Finally several therapeutic uses of such a nanocarrier divalent metal-ion complex are described, for example for slowing down ageing or for the treatment of Cu-ion transport disorders like Alzheimer's disease (AD) or Menkes disease. | 04-01-2010 |
