| FREIE UNIVERSITAET BERLIN Patent applications |
| Patent application number | Title | Published |
|---|
| 20120065344 | COMPOUND MODIFIED BY A PHOSPHORAMIDATE AND/OR PHOSPHONAMIDE GROUP AND USE THEREOF - A modified compound that has at least one further functional group, in particular a bio- or macromolecule, comprising at least one x-fold (x≧1) chemoselectively incorporated phosphoramidate group of general formula (I), NPO(OR | 03-15-2012 |
| 20120036242 | METHOD AND SENSOR NETWORK FOR ATTRIBUTE SELECTION FOR AN EVENT RECOGNITION - A method for attribute selection for an event recognition in sensor networks is provided. The method comprising the following steps: in a configuration phase providing a quantity of attributes by sensor nodes of a sensor network, which characterize an event to be recognized, together with information on the topological origin of the attributes within the sensor network, and selecting a sub-quantity from the quantity of attributes, wherein the selection is made in consideration of the information on the topological origin of the attributes, and in an execution phase performing an event recognition for an event to be currently recognized on the basis of attributes which belong to a selected sub-quantity. | 02-09-2012 |
| 20120016103 | PEPSTATIN A DERIVATIVES - The invention relates to a compound having a structure according to the general formula P3-P2-P1-P1′-P2′ (I), wherein residues P3, P2, P1, P1′ and P2′ are specifically defined and may be, e.g., certain amino acid residues. The invention further relates to the use of said compound and to a method for synthesizing a peptide. | 01-19-2012 |
| 20110255563 | PULSE SHAPER AND LASER WITH PULSE SHAPER - A pulse shaper for compensating group runtime effects is provided. The pulse shaper comprising a first and a second dispersive element. An optical pulse can be coupled to the pulse shaper along a coupling direction such that said pulse exits from the pulse shaper after passing through the first and the second dispersive element along an exit direction. The first and the second dispersive element are formed and arranged to be movable relative to each other such that the path length to be traversed by the optical pulse through the first and the second dispersive element after coupling to the pulse shaper can be adjusted without any change in an offset between the coupling direction and the exit direction. The first and the second dispersive element are arranged in such a way that the shape of the optical pulse experiences a change as the pulse travels through the pulse shaper. | 10-20-2011 |
| 20110182973 | POLYMERASE INHIBITORS AND THE USE THEREOF FOR THE TREATMENT OF TUMORS - The invention relates to polymerase inhibitors, particularly polymerase alpha inhibitors, and the use thereof in the treatment of cell growth disorders, particularly tumor disorders, preferably actinic keratoses, basal cell carcinomas, and/or spinocellular carcinomas. | 07-28-2011 |
| 20100310521 | POLYNUCLEOTIDE SEQUENCE FOR THE INHIBITION OF PHOSPHOLAMBAN SYNTHESIS - A DNA polynucleotide sequence is disclosed that comprises a transcribed sequence, and a promoter sequence. Transcription of the transcribed sequence by an RNA polymerase in a cell renders an RNA a transcript capable of forming a partially self-complementary hairpin structure which can be processed by the cell to an siRNA product that can degrade phospholamban mRNA in such cell. The promoter is a drug inducible conditional promoter or a cardiomyocyte cell-specific promoter or both, operably linked to the transcribed sequence. The promoter is operable by an RNA polymerase naturally occurring in a mammalian cell. | 12-09-2010 |
| 20100255572 | INFLAMMATION-INDUCED ANTI-FLAMMATORY GENE EXPRESSION - According to one embodiment of the present invention, a self regulating DNA non-viral expression vector is provided that allows after non-viral ex vivo gene therapy for the controlled and regulable inflammation-specific expression of anti-inflammatory polypeptide gene products in the recipient's joint tissues. The inventive gene expression construct comprises a RNA polymerase promoter sequence that is induced by inflammation and which is operable in a mammalian cell, a transcribed sequence under the control of said promoter sequence, encoding a transcription product that has the ability to modulate the inflammatory response, and/or encoding the mRNA for a polypeptide gene product that has the ability to modulate the inflammatory response, whereby the inflammatory response is modulated by a negative feed back response of said gene product on said promoter sequence. | 10-07-2010 |
| 20100116668 | MATERIAL SYSTEM AND METHOD FOR PRODUCING THE SAME - A material system having a matrix and nanoparticles embedded therein, wherein the matrix comprises at least one matrix metal, the nanoparticles have an average size of less than 50 nm and the nanoparticles have in each case at least one functional carrier. A method for producing the material system is also disclosed. | 05-13-2010 |
| 20080260830 | Growth Factor Mutants With Improved Biological Activitiy - The invention relates to novel biosynthetic growth factor mutants which exhibit improved biological activity. | 10-23-2008 |
