| FRAUNHOFER U.S.A., INC. Patent applications |
| Patent application number | Title | Published |
|---|
| 20120122831 | METHOD AND DEVICE FOR RAPID DETECTION OF BACTERIAL ANTIBIOTIC RESISTANCE/SUSCEPTIBILITY - Described herein is a method and a device for expediting delivery of an agent to a damaged bacterial cell. In one embodiment, the methods and devices are useful for screening candidate antibiotics. In another embodiment, the methods and devices described herein are used to determine susceptibility of bacteria to an antibiotic. The methods also provide a method for determining an appropriate antibiotic to treat an individual having a bacterial infection. | 05-17-2012 |
| 20120118071 | METHODS AND APPARATUS FOR DETECTING CROSS-LINKING IN A POLYMER - Methods and apparatus for detecting cross-linking in a polymer, wherein, in some exemplary implementations, the polymer may constitute an encapsulation layer for a photovoltaic module. In one example, a polymer sample is physically deformed, and sample information relating to a relaxation or a recovery of the polymer sample in response to the deformation is obtained. The sample information is then compared to reference information relating to cross-linking of the polymeric material so as to determine a degree of cross-linking in the tested polymer sample. In one aspect, such a determination of polymer cross-linking is achieved without adversely affecting a relevant functionality of the polymer/encapsulation layer (e.g., without destruction to the polymer/encapsulation layer). | 05-17-2012 |
| 20120115705 | DISPOSABLE SEPARATOR/CONCENTRATOR DEVICE AND METHOD OF USE - The present invention relates to methods, devices and systems for separation and concentration of particles from liquid and fluid samples. In some embodiments, the separation/concentration is achieved by sequential centrifugation steps. In particular, one aspect of the invention relates to a separation/concentration device which comprises at least a first chamber ( | 05-10-2012 |
| 20120077260 | RESERVOIR-BUFFERED MIXERS AND REMOTE VALVE SWITCHING FOR MICROFLUIDIC DEVICES - The present invention relates generally to the control of fluid flow rate and direction on a microfluidic device. In particular, the present invention provides an integrated valveless microfluidic device, where directional fluid control is controlled using off-chip remote valve switching and fluid flow rate changes are controlled using on-chip flow-rate changing fluid reservoirs. The present invention provides methods and systems for directional fluid control and control of fluid flow rate in an integrated microfluidic device which enables processes with different flow rates to be performed on one device without the need of on-chip valves. | 03-29-2012 |
| 20120034253 | Influenza Vaccines, Antigens, Compositions, and Methods - The present invention relates to the intersection of the fields of immunology and protein engineering, and particularly to antigens and compositions useful in inducing or enhancing an immune response agains influenza antigens. Provided are recombinant protein antigens, compositions, and methods for the production of such antigens in plants. In some embodiments, influenza antigens include hemagglutinin polypeptides, neuraminidase polypeptides, and/or combinations thereof. | 02-09-2012 |
| 20110314575 | Plasmodium Vaccines, Antigens, Compositions and Methods - The present invention relates to the intersection of the fields of immunology and protein engineering, and particularly to antigens and vaccines useful in prevention of infection by | 12-22-2011 |
| 20110313145 | ISOLATION OF RNA - Disclosed herein are methods for purification of RNA from a sample. The RNA can be total RNA or mRNA. The method involves preparing the sample in a solution of lysis buffer and depositing into a first end of a lysis straw such that the sample solution flows through the matrix of the lysis straw and is eluted from the opposite end of the lysis straw, and depositing the eluted material into a first end of a solid phase extraction (SPE) straw, such that the deposited solution flows through the matrix of the SPE straw towards the opposite end of the SPE straw, and eluting the RNA from the SPE straw by depositing a solution of elution buffer, into the first end of the SPE straw, such that the deposited solution flows through the matrix of the SPE straw and is eluted from the opposite end of the SPE straw, wherein purified RNA from the sample is present in the eluate of the SPE straw. When the RNA is total RNA, and the sample is a cell sample, and step b) requires adding a precipitating solution to the eluted material from step a), and depositing the solution into the first end of the SPE straw, wherein the straw comprises silica microspheres, such that the deposited solution flows through the matrix of the SPE straw toward the opposite end of the SPE straw. When the RNA is mRNA and step b) further comprises depositing the solution into the first end of the solid phase extraction (SPE) straw, wherein the straw comprises oligo-dT. Pressure (e.g., at least 10 psi pressure) and heat (e.g., about 60° C.) can be applied to the samples, and/or eluates and/or straws. Examples of lysis buffers, loading buffers and elution buffers are provided. Also disclosed are the specific straws and porous polymer monolith matrix components. | 12-22-2011 |
| 20110311612 | Humanized Neuraminidase Antibody and Methods of Use Thereof - Antibodies against influenza neuraminidase, compositions containing the antibodies, and methods of using the antibodies are provided herein. | 12-22-2011 |
| 20110070609 | Production of Foreign Nucleic Acids and Polypeptides in Sprout Systems - The present invention provides systems and methods for producing a nucleic acid or protein in transgenic sprouted seedlings or sprouted seedlings engineered to transiently express a nucleic acid or protein of interest. The sprouted seedlings of the invention are grown in a contained, regulatable environment, wherein expression of a pharmaceutically active protein is controlled by an exogenously inducible promoter or a viral promoter. The sprouted seedlings may be eaten live or preferably harvested live to preserve the maximal biological activity of the nucleic acid or protein. | 03-24-2011 |
| 20110065122 | METHOD FOR ACCESSING MICROBIAL DIVERSITY - A method of interfering with quorum sensing regulation of genes to promote cell growth is disclosed. The method of is aimed at accessing microbial biodiversity. The method involves obtaining an environmental sample comprising at least one novel (uncultivated in the laboratory) microorganism, contacting the environmental sample with an effective amount of an agent or combination of agents which interferes with the quorum sensing regulation of genes, growing the treated sample in a culture medium containing the quorum sensing signal disrupting agent or agents, and analyzing the colonies of microorganisms grown to demonstrate genetic novelty. | 03-17-2011 |
| 20110060188 | LOW COST DISPOSABLE MEDICAL FORCEPS TO ENABLE A HOLLOW CENTRAL CHANNEL FOR VARIOUS FUNCTIONALITIES - The present invention relates to an endoscopic biopsy forceps ( | 03-10-2011 |
| 20110059130 | PROPHYLACTIC AND THERAPEUTIC INFLUENZA VACCINES, ANTIGENS, COMPOSITIONS AND METHODS - The present invention relates to the intersection of the fields of immunology and protein engineering, and particularly to antigens and vaccines useful in prevention of infection by influenza virus. Provided are recombinant protein antigens, compositions, and methods for the production and use of such antigens and subunit vaccine compositions. In some embodiments, influenza antigens include hemagglutinin polypeptides neuraminidase polypeptides, and/or combinations thereof. | 03-10-2011 |
| 20110027304 | YERSINIA PESTIS ANTIGENS, VACCINE COMPOSITIONS AND RELATED METHODS - The present invention provides antigens and vaccines useful in prevention of infection by | 02-03-2011 |
| 20100227373 | Recombinant Carrier Molecule for Expression, Delivery and Purification of Target Polypeptides - Recombinant carrier molecules having amino acid sequences from thermostable enzymes and methods of use for expression, recovery and delivery of foreign sequences (peptides and polypeptides) produced in different systems (bacteria, yeast, DNA, cell cultures such as mammalian, plant, insect cell cultures, protoplast and whole plants in vitro or in vivo are provided. The recombinant carrier molecule using sequences from lichenase B(Lic B) were also made and used as part of carrier protein to express, recover and deliver a variety of target polypeptides of interest. | 09-09-2010 |
| 20090276757 | Systems and methods for inference and management of software code architectures - Systems, computer program products, and methods for extracting, evaluating, and updating the architecture of a software system are provided. In an embodiment, the method operates by defining the planned architecture for the system and extracting the implemented software code architecture from the source code of the system. The method compares the actual architecture to the planned architecture defined to identify architectural deviations, and suggested changes to the architecture are identified based upon the architectural deviations. The modeled code architecture and defined planned architecture information enables verification and determination of whether a software system's source code conforms to the intended structure of the system. The code architecture and planned architecture comparison also enables analysis and display of the effects that changes to source code may have on the structure of a software system. | 11-05-2009 |
