| FOLDRX PHARMACEUTICALS, INC. Patent applications |
| Patent application number | Title | Published |
|---|
| 20100331297 | MODULATION OF PROTEIN TRAFFICKING - Compounds and compositions are provided for treatment or amelioration of one or more disorders characterized by defects in protein trafficking. A method of treating a disorder characterized by impaired protein trafficking includes administering to a subject or contacting a cell with a compound of Formula I: [formula here] or pharmaceutically acceptable salts or derivatives thereof. | 12-30-2010 |
| 20100305068 | COMPOUNDS AND METHODS FOR MODULATING PROTEIN TRAFFICKING - Disclosed are compositions and methods for modulating protein trafficking and treating or preventing disorders characterized by impaired protein trafficking. Also disclosed are methods for producing a protein and identifying compounds that rescue protein trafficking defects. | 12-02-2010 |
| 20100273776 | INHIBITION OF ALPHA-SYNUCLEIN TOXICITY - Compounds and compositions are provided for treatment or amelioration of one or more symptoms of α-synuclein toxicity, α-synuclein mediated diseases or diseases in which α-synuclein fibrils are a symptom or cause of the disease. | 10-28-2010 |
| 20100122362 | CELLS EXPRESSING ALPHA-SYNUCLEIN AND USES THEREFOR - Disclosed are mammalian neuronal cells expressing alpha synuclein as well as methods of screening to identify compounds that decrease toxicity induced by alpha synuclein expression. Compounds identified by such screens can be used to treat or prevent synucleinopathies such as Parkinson's disease, familial Parkinson's disease, Lewy body disease, the Lewy body variant of Alzheimer's disease, dementia with Lewy bodies, multiple system atrophy, or the Parkinsonism-dementia complex of Guam. | 05-13-2010 |
| 20100004277 | COMPOUNDS AND METHODS FOR MODULATING PROTEIN TRAFFICKING - Disclosed are compositions and methods for modulating protein trafficking and treating or preventing disorders characterized by impaired protein trafficking. Also disclosed are methods for identification of compounds that rescue protein trafficking defects and methods of enhancing protein production. | 01-07-2010 |
| 20080261953 | Compounds, Compositions and Methods of Inhibiting Alpha-Synuclein Toxicity - Compounds and compositions are provided for treatment or amelioration of one or more symptoms of α-synuclein toxicity, α-synuclein mediated diseases or diseases in which α-synuclein fibrils are a symptom or cause of the disease. In one embodiment, the compounds for use in the compositions and methods are heteroaryl acylguanidines, heteroarylhydrazones, dihy-dropyridones, heteroaryl and aryl styryl ketones, and heteroarylpyrazoles. | 10-23-2008 |
