| FINNZYMES OY Patent applications |
| Patent application number | Title | Published |
|---|
| 20120082981 | ENZYME MIXTURE - Polymorphisms are present throughout an organism's genome, and understanding which alleles are present in a particular organism's genome can be advantageous. When probing the identity of these alleles, one must minimize incorrect readings due to inefficiencies in the system. In hydrolysis probe applications, these inefficiencies may be due to over-activity of an exonuclease functionality that excises nucleotides from probes that are only partially, complementary to a region of a target. The present invention provides a mixture that contains a plurality of polymerases including one that has a 5′→3′ exonuclease functionality and one that lacks or substantially lacks it, each in a sufficient relative amount and concentration to increase efficiencies of the system. | 04-05-2012 |
| 20120015831 | METHOD FOR DELIVERING NUCLEIC ACID INTO EUKARYOTIC GENOMES - The present invention relates to genetic engineering and especially to the use of DNA transposition complex of bacteriophage Mu. In particular, the invention provides a gene transfer system for eukaryotic cells, wherein in vitro assembled Mu transposition complexes are introduced into a target cell and subsequently transposition into a cellular nucleic acid occurs. The invention further provides a kit for producing insertional mutations into the genomes of eukaryotic cells. The kit can be used, e.g., to generate insertional mutant libraries. | 01-19-2012 |
| 20110251080 | SAMPLE PROCESSING APPARATUS AND METHOD - The invention relates to a sample processing apparatus comprising a holder for a microtiter plate comprising a plurality of microwells, optical measurement unit for measuring optical responses of samples dosed to the microwells, and a computing unit configured to analyze the optical responses in order to detect dosing failures in said plurality of microwells, and if a dosing failure has been detected in one or more of the microwells, to communicate the existence of the dosing failure to a user of the apparatus through signaling means or to store data indicative of the dosing failure to data storage means for further use. In particular, the invention relates to detecting dosing failures in before, during and after a PCR process. | 10-13-2011 |
| 20100173800 | DELIVERY OF NUCLEIC ACIDS INTO GENOMES OF HUMAN STEM CELLS USING IN VITRO ASSEMBLED MU TRANSPOSITION COMPLEXES - The present invention relates to genetic engineering and especially to the use of DNA transposition complex of bacteriophage Mu. In particular, the invention provides a gene transfer system for isolated human stem cells, wherein in vitro assembled Mu transposition complexes are introduced into a target cell and subsequently transposition into a cellular nucleic acid occurs. The invention further provides a kit for producing insertional mutations into the genomes of isolated human stem cells. The kit can be used, e.g., to generate insertional mutant libraries. | 07-08-2010 |
| 20090191561 | METHODS AND OLIGONUCLEOTIDES FOR DETECTION OF MASTITIS CAUSING BACTERIA - The present invention relates to the field of polymerase chain reaction (PCR) based diagnostic assays. More specifically, the present invention provides a PCR-method for detecting mastitis causing bacteria, particularly | 07-30-2009 |
