| EPPENDORF AG Patent applications |
| Patent application number | Title | Published |
|---|
| 20110286897 | Microtiter plate - Microtiter plate made of plastic, having a plurality of wells in a plate which has at least one break line that divides the plate into various segments. The break line includes a joint line which is formed by molding together various segments of the plate. | 11-24-2011 |
| 20110281775 | DETECTION AND/OR QUANTIFICATION METHOD OF TARGET MOLECULES ON A SOLID SUPPORT - The present invention relates to a method and device for detecting and/or quantifying one or multiple target molecules present in a solution by quantifying online their binding on specific capture molecules immobilized at different locations (spots) of a surface of an optically transparent solid support without substantial detection of target molecules present in solution. The present invention allows multiple target assays to be performed in a simultaneous detection. More particularly, the invention comprises detecting in real-time the hybridization between capture DNA molecules present on a micro-array and target polynucleotides present in solution. The invention is also related to real-time PCR of multiple targets on a micro-array. | 11-17-2011 |
| 20110237455 | ARRAY ANALYSIS FOR ONLINE DETECTION - The invention provides a method and kit for performing the analysis of a microarray surface having immobilized capture molecules used for detection and/or quantification of one or multiple target biological molecules labelled with a fluorophore and being present in a solution comprising a light absorbing agent that has an absorption band which overlaps the emission and/or absorption band of the fluorophore and is not a quencher molecule of the label of the target molecules. | 09-29-2011 |
| 20110212521 | Apparatus and Method for Generating a Tool Motion - The invention relates to an apparatus according to the present invention for generating the motion of a tool, in particular for the work on biological cell material, in particular for performing ICSI, comprises at least one actuator element, an actuated member, a motion section, at which can be arranged a tool and which is linked to the actuated member, the actuated member being elastically deformable, the actuator element being linked to the actuated member such that an actuation by the actuator element elastically deforms the actuated member by a distance, which corresponds to a length change of the actuated member, wherein said length change causes said motion of the motion section. Further, a corresponding method for generating a tool motion is provided. | 09-01-2011 |
| 20110209564 | Positioning Device for a Sample Distribution Apparatus, Sample Distribution Apparatus with Positioning Device and Method for Positioning - The invention relates to a positioning device for a sample distribution apparatus, in particular a pipetting apparatus, providing a first part, at which a sample transport device can be arranged, a second part, at which a sample holder can be arranged, wherein the first part and the second part are arranged moveable in relation to each other between a first position and an adjusted target position of the first and second part for performing a positioning motion, such that a sample can be conveyed towards the sample holder by the positioning motion between the first position and the adjusted target position and is conveyable at the target position by release from the sample transport device to the sample holder, or can be conveyed in the sample transport apparatus towards the sample holder by the positioning motion between the first position and the adjusted target position and is conveyable by a motion of the sample transport device relative to the first part into a release position and is conveyable at the release position by release from the sample transport device to the sample holder, wherein an actuation motion is provided, which serves the conveyance of the sample, a positioning auxiliary device, which provides at least one means for limiting and the relative mobility of the first and the second part in the adjusted target position, which provides, preferably, at least one means for adjusting the n-th target position from a plurality of N predetermined target position as the adjusted target position, which, preferably, provides at least one means for changing of the adjusted target position from the n-th target position to an (n+1)-th target position, and which further provides at least one first means for coupling of said actuation motion and said positioning auxiliary device, or to the at least one means for changing of the same such that the actuation motion can effect the change from said n-th target position to said (n+1)-th target position via said at least one first means for coupling. The invention relates to a corresponding working method for the automatical change of a position of a first part relative to a second part and relates further to a sample distribution apparatus with such a positioning device. | 09-01-2011 |
| 20110181272 | Metering apparatus for liquids and method for metering liquids - A metering apparatus for liquids and a method for metering liquids which facilitate the operation of a further metering after detaching the pipette point or syringe | 07-28-2011 |
| 20110170094 | Cuvette, Insert, Adapter and Method for Optically Examining Small Amounts of Liquid - Cuvette, comprising at least one measuring area on each one of two arms that are pivotally connected to each other such that from a swung-apart condition, they can be swung together into a measuring position in which the two measuring areas have a distance for positioning a sample between the measuring areas, and means for positioning the two arms in a measuring position in a cuvette shaft of an optical measuring device with a sample between the two measuring areas in a beam path of the optical measuring device that crosses the cuvette shaft. | 07-14-2011 |
| 20110168590 | Cover - A cover for an apparatus including a substrate defining the cover and having an exterior surface; a layer over the exterior surface of the substrate; a first portion of the substrate, underlying the layer, having a first composition and defining a first portion of the cover; a second portion of the substrate, underlying the layer, having a second composition and defining a second portion of the cover; wherein the first portion of the cover and the second portion of the cover are substantially opaque in exterior ambient lighting and the second portion of the cover is translucent to backlighting. | 07-14-2011 |
| 20110164245 | Cuvette, Insert, Adapter and Method for Optically Examining Small Amounts of Liquid - A cuvette comprising at least one insert with two measuring surfaces, wherein the insert is a measurement tip, which has the two measuring surfaces on one end, which is distanced from another end of the measuring tip, and an adapter for insertion in a cuvette shaft of an optical measuring device and means of insert and adapter for releasably holding the at least one insert in the adapter with the measuring surfaces at a separation distance from each other for the positioning of a sample between the measuring surfaces in a beam path of the optical measuring device passing through the cuvette shaft. | 07-07-2011 |
| 20110163013 | Apparatus and Method for Moving Particles in a Fluid - The invention relates to an apparatus, in particular for moving particles in a fluid at Reynolds numbers larger than 0.5, which comprises a container section adapted to hold said fluid, and which is adapted to perform a displacement process, which includes a number of repeated displacements of said container section, comprises at least one actuating device, which is adapted to perform said displacements, at least one connecting means, which connects said container section to said actuating device, said displacement comprising a first motion of said container section from a first position to a second position and a second motion of said container section from said second position back to said first position, wherein during said first motion said container section is at least temporarily moved with a first velocity, and wherein during said second motion said container section is at least temporarily moved with a second velocity, which is different from said first velocity, and wherein by means of said displacement process, a force is acting upon said particles in the fluid, which is capable of inducing a directed motion of said particles in relation to said container section, wherein said first and second velocity of said container section control, i.e. influence or determine, said motion of the particles. The invention further relates to a method for in particular moving particles in a fluid at Reynolds numbers larger than 0.5. | 07-07-2011 |
| 20110151519 | Laboratory Apparatus with an Arrangement for the Tempering of Samples and Method of Tempering Samples - The invention relates to a laboratory apparatus, in particular for performing a polymerase chain reaction (PCR) in a plurality of PCR-samples, which comprises an arrangement for tempering samples, the arrangement comprising a tempering block for the tempering of samples, the tempering block comprising a reception side, which provides receptacles for receiving sample vessels, and a contact side for the contact of at least one tempering device, at least one tempering device, arranged in an area of said contact side, a pressure device, which comprises a pressure element and an auxiliary element, said at least one tempering device being arranged between said auxiliary element and the tempering block, the pressure element being linked to said auxiliary element and to the tempering block, and being arranged to press said at least one tempering device against the tempering block by pressing said auxiliary element against said at least one tempering device, wherein at least one tempering device is shaped and arranged in said area to at least partially surround by itself said pressure element. | 06-23-2011 |
| 20110111489 | SENSOR ADAPTER, METHOD FOR THE MANUFACTURE THEREOF, METHOD FOR THE USE OF A SENSOR IN THIS SENSOR ADAPTER AND BIOREACTOR WITH THIS SENSOR ADAPTER - A sensor adapter is described for the noninvasive positioning of a sensor, especially of an electrochemical sensor, in a medium. The sensor adapter comprises an accommodating channel, in which the sensor can be positioned and the one end region of which is closed off by a semipermeable membrane. Moreover, the sensor adapter comprises a hollow cylindrical sealing structure, which is disposed within the accommodating channel coaxially with the longitudinal axis of the latter and with which the sensor can be disposed gas tight adjacent to the semipermeable membrane. | 05-12-2011 |
| 20110088493 | Syringe, syringe family and metering device - Syringe for use with a metering device comprising a centring element with an axial through-passage in a receiver for a syringe cylinder and an axially displaceable piston receiver for a syringe piston, comprising
| 04-21-2011 |
| 20110072915 | HANDHELD PIPETTING APPARATUS - A handheld pipetting apparatus for metering liquids, with a handleable pipette housing, at least one accommodation for a fastening portion of a syringe cylinder of a syringe, at least one plunger accommodation in an accommodation body for a plunger fastening portion of a syringe plunger of the syringe, fastening means for detachably holding the fastening portion in the accommodation and the plunger fastening portion in the plunger accommodation, at least one displacement device with a displacement chamber and a shiftable chamber wall limiting the same, for displacing a fluid; at least one seat for detachably holding a pipette point, a channel, connecting a hole in the seat with a displacement chamber, and at least one drive device, which is connected to and/or couplable with the accommodation body and/or the chamber wall, for shifting the accommodation body with respect to the accommodation, and/or the chamber wall with respect to the displacement chamber. | 03-31-2011 |
| 20110031420 | Optical Sensor System on a Device for the Treatment of Liquids - Optical sensor system on a device for the treatment of liquids with at least one device for the projecting of light in the direction of an optical axis onto at least one illumination area in the space, an adjustment device for the adjustment of the relative position of the at least one illumination area and a boundary surface in a direction diagonal to the optical axis, an adjustment device for the adjustment of the relative position of the at least one illumination area and the boundary surface in the direction of the optical axis, a control device for controlling the adjustment devices, such that they simultaneously adjust the relative position of the at least one illumination area and the boundary surface diagonal to the at least one device for the imaging of the at least one illumination area during the adjustment of the relative position onto at least one photodetector and an evaluation device connected with the at least one photodetector for the evaluation of the at least one measurement signal. | 02-10-2011 |
| 20110027863 | LABORATORY VESSEL WITH SHIFTABLE VESSEL CLOSURE - The present invention pertains to vessels with a vessel closure, and in particular to laboratory vessels with a shiftable closure assembly. The laboratory vessel comprises a container comprising an outwardly extending neck with an opening which provides access to the interior of said container, at least one guiding device comprising a guided member and a guiding member, a closure assembly comprising a vessel closure and at least one guided member which is part of said at least one guiding device, which is characterized in that said vessel closure is arranged to be shifted away from said opening to provide access to the interior of the container, wherein said at least one guiding device guides the shifting of the closure assembly and retains it in connection with the container even in the position in which the vessel closure is removed from the opening. | 02-03-2011 |
| 20110003376 | Cell Culture Dish - A cell culture dish, comprising: a dish with a bottom wall and a circumferential side wall standing upward from the same, a lid, which sits sealingly on the side wall in an aeration position, and means for holding the lid on the dish above the sealing position in an aeration position in which there is an aeration gap between side wall and lid, wherein these means are adapted to be overcome by pressing the lid and the dish together in order to bring the lid from the aeration position into the sealing position. | 01-06-2011 |
| 20100333001 | DEVICE FOR DISPLAYING A FUNCTION CHART - A device for the dimensionally variable display of a function chart on a display ( | 12-30-2010 |
| 20100324834 | Device and Method for Radiometric Measurement of a Plurality of Samples - The invention relates to an apparatus for radiometrically investigating a plurality of samples, with: a radiation device providing a plurality of radiation elements, a radiation element comprising at least one emitter element, wherein the radiation device preferably provides at least two emitter elements which provide radiation with different radiation spectra, wherein at least two of said emitter elements are adapted to emit radiation during time periods which at least partially overlap, and a control device, controlling said radiation elements, a sample holder member providing a plurality of sample positions for supporting a plurality of samples, wherein device and the sample holder member are preferably at least a part of the radiation adapted to be moved against each other during the investigation procedure and wherein at least one radiation element is adapted to irradiate a sample with radiation via a first optical path which causes the sample to emit sample radiation with at least one sample radiation frequency via a second optical path towards at least one detection device, said at least one detection device being adapted to detect the sample radiation of at least two samples as a sum signal during time periods which at least partially overlap; and an evaluation device which is adapted to evaluate the sample radiation of at least one individual sample from said sum signal. The invention relates further to a method for photometrically investigating sample radiations of at least one sample, which are caused by the radiation of N emitter elements of at least one radiation element wherein said N emitter elements are emitting radiation during time periods which at least partially overlap, to detect the sample radiation of at least two samples as a sum signal during time periods which at least partially overlap and to evaluate the sample radiation of at least one individual sample from said sum signal. | 12-23-2010 |
| 20100286382 | DISPOSABLE LABORATORY IMPLEMENT - A method of processing a liquid sample containing an initial quantity of nucleic acids that involves providing a plastic, disposable laboratory implement having at least one transparent wall segment made of a polypropylene mixed with an amount of a clarifier additive that is at least twice as high as is necessary to obtain transparency in the polypropylene, wherein the transparent wall segment exhibits a surface gloss greater than 160 as measured per DIN 67530 at an angle of 60°, bringing the liquid sample into contact with the at least one transparent wall segment and removing the liquid sample from the at least transparent wall segment, wherein the nucleic acid adsorption ratio for the transparent wall segment is less than 3 (wt/wt) relative to relative to the initial quantity of nucleic acids in the liquid sample. | 11-11-2010 |
| 20100285599 | Method and Device for the Quantitative Real Time Analysis of Fluorescent Samples - A method for the quantitative real time analysis of fluorescent samples is provided, at which each of the samples is excited to fluoresce by a sample individual light source ( | 11-11-2010 |
| 20100266457 | Carrier for Pipette Tips - A carrier for pipette tips, with
| 10-21-2010 |
| 20100266454 | Metering Device - A metering device for utilisation with a syringe, which features on a syringe cylinder a fastening portion with at least one axially directed sensing surface projecting from the upside, and at least one alignment nose projecting from the outer perimeter of the fastening portion, and a plunger with a plunger rod, the metering device having an accommodation for the fastening portion of the syringe cylinder, the accommodation having an axial opening for axially inserting the fastening portion into a fastening position, a sensing device disposed in the accommodation with at least one sensing means projecting from a basis surface of the sensing device facing the axial opening, for sensing the at least one sensing surface of a fastening portion inserted in a fastening position. | 10-21-2010 |
| 20100193524 | PRESERVING CONTAINER - Preserving container, characterized in that a sample container ( | 08-05-2010 |
| 20100167415 | ALIQUOTTING DEVICE - Aliquotting device on the basis of a micro litre test tube ( | 07-01-2010 |
| 20100160830 | CODING FOR A SAMPLE CARRIER - Coding for a sample carrier having at least a swab shaft and a piece of cotton wool or the like as sample collector, characterized in that said swab shaft ( | 06-24-2010 |
| 20100155037 | CONTAINER AND A DEVICE FOR INDIRECTLY COOLING MATERIALS AND METHOD FOR PRODUCING THE CONTAINER - The present relates to a container and to a device for indirect material cooling and to a method for producing the container according to the invention. Through the present invention a much more efficient indirect heat transfer is facilitated from the exterior of the container into the interior of the container. The improvement of the heat conductivity and of the heat transfer of centrifuge containers yields a reduction of the necessary power of the refrigeration system for cooled centrifuges. Through the higher performance of the centrifuge a higher speed can be run for identical centrifuge temperatures and/or at the same centrifuge temperature and speed, the input power of the refrigeration unit can be reduced. | 06-24-2010 |
| 20100150203 | Tempering apparatus with testing device and method for testing a tempering apparatus - The invention relates to a tempering apparatus for the execution of a tempering program for at least one sample, in particular PCR-sample, comprising: at least one tempering block, which is configured for the reception of at least one sample, at least one tempering device, which is arranged for tempering said at least one tempering block, at least one temperature measurement device, which is assigned to said tempering device, at least one control loop for the regulation of a temperature, to which at least one tempering device and at least one temperature measurement device, which is assigned to said at least one tempering device, are assigned to, at least one control device, which is configured for the control of the tempering of the at least one tempering block, wherein the tempering apparatus comprises at least two temperature measurement devices, which are assigned to at least one control loop, and that to the tempering apparatus a testing device for performing a test method is assigned to, wherein said testing device comprises a signal-connection to at least one of said at least two temperature measurement devices, such that by means of said signal-connection at least one testing quantity of the tempering apparatus is detectable, which characterizes the operational status of the tempering apparatus. The invention further relates to a method for testing of a tempering apparatus, wherein the method comprises the following steps: starting of the method; operation of at least said first tempering device for the duration of at least one first period from at least one first time; detection of at least one measurement temperature from said at least one first temperature measurement device, which is assigned to said first tempering device, at least at a second time; determining at least one first testing quantity of the tempering apparatus by using said at least one measurement temperature; and comparison of said first testing quantity with one reference quantity. | 06-17-2010 |
| 20100143197 | Container Holder - A container holder for a multiplicity of tubular sample containers with a frame made of a rigid plastic material, comprising a panel with a multiplicity of holes, and a coating of the frame which is made of an elastic plastic material or of rubber, and which partially closes off the cross section of the holes. | 06-10-2010 |
| 20100116896 | THERMOSTAT APPARATUS INCLUDING CALIBRATION DEVICE - A thermostat apparatus is provided for simultaneous thermostatting of at least one sample that is contained, e.g., in sample vessels, having receptacles for receiving the samples or sample vessels, the apparatus having at least one thermostat device for generation of a desired temperature or temperature profile, having a control device for regulating the heating and/or cooling power of the at least one thermostat device, and having at least one regulating temperature sensor that is provided to determine a parameter that is indicative of the temperature and is connected to the control device. In addition to the at least one regulating temperature sensor, at least one calibrating temperature sensor is provided that is arranged in spatial proximity to an allocated regulating temperature sensor to determine a parameter that is indicative of the temperature, and is connected to the control device. | 05-13-2010 |
| 20100116069 | CONTAINER SEAL WITH INTEGRATED SAFETY ARRANGEMENT FOR A SAMPLE CARRIER - Container seal having an integrated safety arrangement for a sample carrier, wherein the container seal ( | 05-13-2010 |
| 20100113298 | DETECTION OF RNA WITH MICRO-ARRAYS - A method for the detection and quantification of RNA via micro-arrays, wherein a first DNA molecule is added to a RNA-pool to be tested, which first DNA molecule is complementary to at least a first segment of a RNA of interest, as well as a second DNA molecule complementary to a second segment of the RNA of interest, which second segment is different from said first segment and further has at the 3′ and 5′ ends specific nucleotide sequences, which are not complementary to the RNA of interest. The DNA molecules are contacted with the RNA-pool under conditions allowing hybridization of complementary strands. Afterwards all RNA molecules are removed to which said first DNA molecule has not hybridized. After releasing of the second DNA molecules, they are contacted with an array having at specific locations thereof probes specific for particular nucleotide sequences. | 05-06-2010 |
| 20100087003 | DEVICE AND METHOD FOR THE MECHANICAL DECOLLATION OF CELLS FROM A CELL COMPOSITE - A device for mechanically decollating cells from a cell composite, particularly a shear rotor, a cell isolation unit including such a shear rotor and a method for decollating cells from a cell composite. The aforementioned device includes a rotor having a rotor wall, which is concentrically arranged in a receptacle. A rotor seat is connected to a motor and to which the rotor can be fixed in a detachable manner. A rotational movement of the motor can be transmitted to the rotor by means of the rotor seat. The rotor tapers longitudinally towards the bottom of the receptacle so that different circumferential speeds of the rotor can be transmitted to a liquid sample in the receptacle via the rotor wall. | 04-08-2010 |
| 20100083775 | PIPETTING DEVICE - The present invention is related to a pipetting device with means for detachably connecting with at least one pipette tip, at least one displacement device, a driving device for driving a displacement member of the displacement device and an adjustment device with a lead screw nut and a lead screw for adjusting the metering volume. | 04-08-2010 |
| 20100083774 | FORENSIC PIPETTE - Forensic pipette on the basis of a microliter pipette tip having a pipette body composed of screwed together a pipette's upper, middle, and lower parts and a syringe inserted into the middle part, characterized in that in said screwed state a cannula is guided from an outlet of said lower part through a screw connection into said middle part and thus into the interior of the syringe body, wherein said connection of the cannula with the interior can be established during a screwing operation by piercing the syringe body, in that in the region of the outlet a sample carrier is provided with a sample collector having the basic shape of a microliter pipette tip, and in that said syringe piston is connected with a fine advancement drive and with a control element in form of a knurled screw for a dosed force exertion onto the syringe content. | 04-08-2010 |
| 20100083773 | SAMPLE CARRIER - Sample carrier in form of a microliter pipette tip for securing microbiological, virological, genetic, medical, veterinary medical, forensic, criminalistic and technical samples, having technical means for being attachable to a tip holder, a conventional microliter pipette or a medical syringe and having an opposite pointed outlet with an opening, characterized in that a sample collector is attached in such a way directly in the region of said opening, that wetting of the sample collection is feasible from the inside of the microliter pipette tip through said opening. | 04-08-2010 |
| 20100007947 | METHOD FOR, IN PARTICULAR, OPTICAL EXAMINATION OF THE SURFACE OF A SAMPLE CARRIER FOR BIOLOGICAL OBJECTS - Method for, in particular, optical examination of the surface of a sample carrier for biological objects, in which the sample carrier is arranged in the spatially-fixed observation area of a measuring facility, whereby the observation area covers a partial area of the surface of the sample carrier, and the sample carrier is moved with respect to the observation area, whereby, for examination, the sample carrier is displaced in the direction of an axis that extends in the plane of the sample carrier and rotated simultaneously in this plane. | 01-14-2010 |
| 20090283512 | Thermal Device - A device for heating of covers of reaction vessels including a directly and/or indirectly heated plate having an upper side which is designed with at least one or without a recessed portion, and a lower side, wherein the heated plate has at least one portion, which is translucent in the optical spectral region, at least one transparent element selected from the group of foils, plates and cuboids for covering portion of the heated plate which is translucent in the optical spectral region, wherein the at least one transparent element does not overlie the recessed portion of the heated plate; and a means for thermal insulating, wherein said means has at least one region, which is translucent in the optical spectral region and which encloses/covers the components defined. | 11-19-2009 |
| 20090253198 | CELL CULTURE DISH - The present invention relates to a to a cell culture dish and particularly to a Petri dish. In the present cell culture dish the wall portion of the base and the top portion of the cover are both provided with markings enabling the correlation of particular cell growth areas to particular coordinates permitting retrieval of particular growth areas avoiding disturbing markings provided on the bottom of the dish. | 10-08-2009 |
| 20090253197 | CULTURE PLATE COMPRISING A LID FOR LATERAL VENTILATION - The present invention pertains to a culture plate, and in particular to a culture plate comprising a lid wherein the peripheral side wall of the lid is formed at least partially of at least one filter element made of a filter material. This enables lateral, uniform ventilation of the culture plate even in a stacked arrangement of the culture plate, avoiding at the same time significant loss of culture medium by evaporation. | 10-08-2009 |
| 20090237655 | APPARATUS FOR POSITIONING A CUVETTE IN AN OPTICAL BEAM PATH OF AN OPTICAL MEASURING INSTRUMENT - An apparatus for positioning a cuvette in an optical beam path of an optical measuring instrument, with a shaft for axially inserting a cuvette, and means for pressing a cuvette against at least one wall surface of the shaft, which comprise at least one arrangement of a magnet, stationarily arranged with respect to the shaft, and a magnet movable with respect to the same, which are oriented such that the movable magnet tends to occupy a certain position with respect to the stationary magnet, in which the movable magnet engages at least partially into the shaft. | 09-24-2009 |
| 20090218518 | APPARATUS FOR CARRYING OUT REAL-TIME PCR REACTIONS - Apparatus for carrying out real-time PCR reactions, including a thermocycler having a reaction region with a plurality of temperature-regulable receptacles for reaction vessels, an illumination device, which has a plurality of light-emitting diodes and is assigned to the reaction region and by means of which excitation light can be radiated into the receptacles, a detector device, which generates measured values in a manner dependent on a measured light intensity, optical devices defining a beam path that leads from the illumination device to the receptacles and from there to the detector device, a reference device, which generates a reference measured value by measurement of the light intensity of a light-emitting diode, and an evaluation device, which takes into account the reference measured value with the measured values, wherein the reference device has a reference light-emitting diode, the light of which is coupled into the beam path behind the reaction region. | 09-03-2009 |
| 20090215638 | ANTIBIOTIC SUSCEPTIBILITY AND VIRULENCE FACTOR DETECTION IN PSEUDOMONAS AERUGINOSA - The present invention relates in general to the detection of antibiotic resistance determinants in | 08-27-2009 |
| 20090213478 | OPTICALLY ACCESSIBLE COVER - The present invention relates to a means for covering and to a device for performing processes and/or reactions involving at least one sample, which are conducted in a temperature-controlled environment and which require optical access to at least one sample. | 08-27-2009 |
| 20090197775 | NUCLEASE ON CHIP - The present invention pertains to a method for determining point mutations on micro-arrays/biochips using a nuclease capable to selectively digest hybridized DNA strands into two DNA fragments, said hybridized DNA strands containing a nucleotide mismatch or nucleotide deletion. The occurrence and/or location of such DNA fragments are indicative for a point mutation. | 08-06-2009 |
| 20090163377 | DETECTION AND/OR QUANTIFICATION METHOD OF TARGET MOLECULES ON A SOLID SUPPORT - The invention relates a method for detecting and/or quantifying different target molecules being bound at different locations (spots) of a surface of an optically transparent solid support having a refractive index n | 06-25-2009 |
| 20090155885 | DEVICE AND METHOD FOR THE INCUBATION OF CELLS - Device for the incubation of cells comprising a sterile or sterilisable, portable receptacle for enclosing in a contamination-proof manner at least one integrated and/or insertable culture vessel for accommodating cells with at least one closable opening for introducing and/or removing cells and/or culture medium and/or a culture vessel into and/or from the receptacle and at least one device for creating culture conditions in the receptacle. | 06-18-2009 |
| 20090155855 | COVER FOR SAMPLE WITH HOMOGENOUS PRESSURE APPLICATION - The present invention relates to means for covering one or more sample(s) that are suitable to avoid or minimize evaporation and/or condensation of any vaporizable substance that may be present in the sample(s) or reaction mixture(s), in particular evaporation of substance at the fringes of a vessel or an array of vessels or condensation of said substance on the lid of a reaction vessel or a plate/block containing the sample(s) and/or the means for covering. This is achieved by providing a device comprising, among others, a force distribution unit that comprises at least one medium or material that is unable to withstand a static shear stress and deforms continuously under the action of a shear force. In a preferred embodiment, this medium or material is a gas, a shear force. | 06-18-2009 |
| 20090139351 | PIPETTE - A pipette with a pipette housing, in which are arranged an accommodation for the fastening portion of a syringe cylinder of a syringe, a plunger accommodation in an accommodation body for a syringe plunger of the syringe, fastening devices for reversibly fixing the fastening portion and the syringe plunger in the accommodations, and plunger setting devices for shifting the accommodation body in the pipette housing, with a pull-up member for removing the accommodation body from the accommodation, and an actuation member for drawing the accommodation body near to the accommodation. | 06-04-2009 |
| 20090087343 | GRIPPING TOOL, DOSAGE TOOL AND TOOL SUPPORT FOR AN AUTOMATIC LABORATORY MACHINE - Gripping tool for automatic laboratory machines, with gripping appliances for gripping vessels, an appliance for converting and/or transferring of movements, the power take-off of which is coupled with the gripping appliances in order to drive them, a coupling appliance for detachable connection with a drive appliance of a tool support of an automatic laboratory machine, which is coupled with the drive of the appliance for converting and/or transferring in order to drive it, and a mounting appliance for detachable mounting of the gripping tool on the tool support of the automatic laboratory machine, while the coupling appliance is connected with the drive appliance of the tool support. | 04-02-2009 |
| 20090032743 | LABORATORY APPARATUS FOR SIMULTANEOUSLY CARRYING OUT REACTIONS IN A PLURALITY OF SAMPLES - The invention relates to a laboratory apparatus for simultaneously carrying out reactions in a plurality of samples which are arranged in an array. The apparatus includes an illumination device, which emits illumination light onto the samples, a detection device, which generates a signal dependent on the light intensity of the light coming from the samples and which forwards the signal to an evaluation device, and a monitoring device for checking the functioning of the illumination device. The illumination device has a plurality of light-emitting diodes assigned in each case to one of the samples, and the monitoring device has electrical devices which can be used to perform an electrical functional check of the light-emitting diodes. The monitoring device is adapted to generate a signal when a functional disturbance of a light-emitting diode is ascertained. | 02-05-2009 |
| 20080318280 | COVER FOR AN ARRAY OF REACTION VESSELS FOR ONE-STEP OPERATION MODUS - The present invention relates to means for covering one or more sample(s) that are suitable to avoid or minimize evaporation and/or condensation of any vaporizable substance that may be present in the sample(s) or reaction mixture(s), in particular evaporation of substance at the fringes of a vessel or an array of vessels or condensation of said substance on the lid of a reaction vessel or a plate/block containing the sample(s) and/or the means for covering. This is achieved by providing a device comprising, among others, a means for positioning a covering means and a means for guiding at least one lid of the covering means. | 12-25-2008 |
| 20080304082 | OPTICAL SENSOR SYSTEM ON AN APPARATUS FOR TREATING LIQUIDS. - An optical sensor system on an apparatus for treating liquids, with a device for projecting light to at least one illumination position in space, at least one device for imaging the at least one illumination position on at least one photo detector in order to supply a measurement signal depending on the received light, wherein the device for projecting is a device for simultaneously projecting light to plural illumination positions and/or the device for projecting is a device for simultaneously projecting light under different angles to the same illumination position, and/or plural photo detectors are existent, and an analysing unit connected to the at least one photo detector for analysing the at least one measurement signal. | 12-11-2008 |
| 20080280775 | Determination of Antibiotic Resistance in Staphylococcus Aureus - The present invention relates to the detection of antibiotic resistance determinants in | 11-13-2008 |
| 20080280330 | COVER FOR SAMPLE WITH SAMPLE-SIZE INDEPENDENT HEIGHT ADJUSTMENT - The present invention relates to a device and a method for controlling the temperature of at least one sample. The device comprises at least the following means: (a) means for accommodating at least one sample; (b) means for heating and/or cooling at least one sample; (c) means for covering at least one sample. These means for covering at least one sample comprise at least one movable contact area and first and second means for fixating said at least one movable contact area in at least one defined direction relative to the sample. Therein said first means for fixating matingly engages with a corresponding second means for fixating. | 11-13-2008 |
| 20080227658 | Cdna Microarrays With Random Spacers - The present invention discloses an improved cDNA microarray, which employs spacers of random sequence and a length of the spacers of at least 50 to 80 nucleotides. The inventive cDNA microarray may be employed for example in fields like the determination of gene expression, DNA sequencing, fingerprinting or mapping. In addition, a method for the preparation of the cDNA microarray, the use of spacer molecules with random sequence and a kit are specified. | 09-18-2008 |
| 20080210700 | Thermocycler - A thermocycler having a base fitted with a temperature-controlled receiving segment for reaction vials is provided. The thermocycler further includes a top, which can be moved into its operational position above the receiving segment and a hermetic seal or wall configured in the top in its operational position that extends between the top and the base thereby sealing both the top and the base. | 09-04-2008 |
| 20080206846 | Thermocycler - A thermocycler is provided that includes a temperature-controlled receiving segment for reaction vials, a top which can be assembled to said base and which in the assembled state may be moved from an open position into an operational position above the receiving segment, an optics configured in the top, where the optics and/or said receiving segment are configured with play in the top respectively the base, the play allowing a relative displacement between the optics and the receiving segment sufficient to adjust the optics relative to the receiving segment, and at least 2 positioning elements are present at each base and each top to allow reproducible alignment between the optics and the receiving segment in a mutually adjusted position. | 08-28-2008 |
