Endologix, Inc. Patent applications |
Patent application number | Title | Published |
20160030051 | SYSTEMS AND METHODS FOR FORMING MATERIALS IN SITU WITHIN A MEDICAL DEVICE - A method for forming a material in an in situ medical device by initiating polymerization of water soluble polymer precursors in an aqueous solution during or after transport of the polymerizable solution from its storage container to a space inside the in situ medical device is described. The stored aqueous solution with water soluble precursors lacks a free radical initiator which, in a powder form, is introduced into the aqueous solution during or after its transport into the space inside the in situ medical device. This storage and delivery system provides greater stability to the stored aqueous solution, allowing it to be stored at ambient temperature and providing extended shelf life over the solutions used in existing in situ polymerization systems. The flexibility to store and deliver/transport only one aqueous solution, instead of requiring the use of two different solutions, is also a benefit. | 02-04-2016 |
20150250989 | METHOD AND SYSTEM FOR TREATING ANEURYSMS - Methods for treatment of aneurysms using a sequential manifold console to deploy multiple filling structures are provided herein. In one aspect, aneurysms are treated by simultaneously filling two double-walled filling structure using a sequential manifold console to guide a user in the steps to be followed in the procedure and to reliably achieve a consistent and durable aneurysmal treatment using a curable medium. The structures may be delivered over balloon deployment mechanisms in order to shape and open tubular lumens therethrough. Pairs of filling structures delivered to the aneurysm from different access openings of a patient can be simultaneously prepared and pressurized from a single treatment console when treating abdominal aortic aneurysms using the described systems and methods. | 09-10-2015 |
20140277385 | METHOD FOR FORMING MATERIALS IN SITU WITHIN A MEDICAL DEVICE - A method for forming a material in an in situ medical device by initiating polymerization of water soluble polymer precursors in an aqueous solution during or after transport of the polymerizable solution from its storage container to a space inside the in situ medical device is described. The stored aqueous solution with water soluble precursors lacks a free radical initiator which, in a powder form, is introduced into the aqueous solution during or after its transport into the space inside the in situ medical device. This storage and delivery system provides greater stability to the stored aqueous solution, allowing it to be stored at ambient temperature and providing extended shelf life over the solutions used in existing in situ polymerization systems. The flexibility to store and deliver/transport only one aqueous solution, instead of requiring the use of two different solutions, is also a benefit. | 09-18-2014 |
20140249615 | APPARATUS AND METHOD OF PLACEMENT OF A GRAFT OR GRAFT SYSTEM - An endoluminal prosthesis system deployable in a region of a patient's vasculature having one or more branch vessels, having a main graft body having a first opening in a wall portion of the main graft body and a pre-loaded guidewire positioned inside the main graft body and advanced through the first opening. One or more branch grafts can be attached to the main graft body to cover one or more openings in the main graft body. | 09-04-2014 |
20130253638 | ENDOLUMENAL VASCULAR PROSTHESIS WITH NEOINTIMA INHIBITING POLYMERIC SLEEVE - The present invention is related to a low profile endolumenal prosthesis. The prosthesis comprises a radially expandable tubular wire support and an expanded PTFE membrane. The density, wall thickness and intranodal distance of the ePTFE are selected to inhibit the formation and nourishment of a viable neointima on the inner surface of the prosthesis, through the ePTFE membrane. | 09-26-2013 |
20130253632 | DEVICES AND METHODS TO TREAT VASCULAR DISSECTIONS - A device system and method for the treatment of aortic dissections comprising placing a stent in the true lumen and displacing the blood in the false lumen with an inflatable bag. | 09-26-2013 |
20130138200 | BIFURCATED GRAFT DEPLOYMENT SYSTEMS AND METHODS - A method for deploying an endoluminal vascular prosthesis using a deployment catheter that has at least a main graft portion and a first branch graft portion. The deployment catheter preferably comprises an elongate, flexible catheter body having a proximal end and a distal end, and an outer sheath and an inner core that is axially moveable with respect to the outer sheath. The catheter preferably comprises a main graft restraint that has a main graft release mechanism comprising a main graft sheath and a suture threaded through a plurality of the openings in the main graft sheath. The catheter further comprises at least one branch graft restraint comprising at least one branch graft release mechanism. | 05-30-2013 |
20120277847 | CATHETER SYSTEM AND METHODS OF USING SAME - Some embodiments are directed to a catheter system comprising an introducer having a main body, an introducer sheath projecting from the main body, and a first seal supported within the introducer and a catheter having a main body, an outer sheath projecting from the main body, a second seal supported within the catheter, and an inner core configured to be advanced axially through the main body, the second seal, and the outer sheath. The introducer can be configured to be selectively engageable with the catheter so that the catheter can be selectively and removably linked with the introducer in the axial direction. The catheter system can also be configured such that, when the introducer and the catheter are linked, the catheter can be rotatable relative to the introducer. The introducer can be configured to radially restrain an endoluminal prosthesis. | 11-01-2012 |
20120277846 | APPARATUS AND METHOD OF PLACEMENT OF A GRAFT OR GRAFT SYSTEM - An endoluminal prosthesis system deployable in a region of a patient's vasculature having one or more branch vessels, having a main graft body having a first opening in a wall portion of the main graft body and a pre-loaded guidewire positioned inside the main graft body and advanced through the first opening. One or more branch grafts can be attached to the main graft body to cover one or more openings in the main graft body. | 11-01-2012 |
20120226341 | CATHETER SYSTEM AND METHODS OF USING SAME - A modular catheter system including a sheath projecting distally from a delivery catheter having a main body module An inner core module carrying a stent thereon, the inner core being axially movable through the main body of the delivery catheter and the delivery catheter sheath, a handle member supported by the main body of the delivery catheter, the handle member being selectively axially engageable with the inner core such that the handle member and the inner core move together in an axial direction when the handle member is engaged with the inner core; and an adjustment member supported by the main body, the adjustment member being configured such that rotation of the adjustment member causes the adjustment member to move axially along the main body by either axially sliding the handle member relative to the main body or by rotating the adjustment member. | 09-06-2012 |
20120203264 | Graft Systems Having Semi-Permeable Filling Structures and Methods for Their Use - Aneurysms are treated by filling at least one double-walled filling structure with a filling medium within the aneurysm, such as filling structures having a membrane that allows water molecules to permeate across the membrane in response to a water potential differential across the membrane. The transport of fluid across the membrane allows the bag to expand or shrink to accommodate changes in the size or shape of the aneurysm, thereby maintaining a seal between the filling structure against the vessel wall and maintaining apposition of the filling structure against the inside surface of the aneurysm. Transport of water molecules into or out of the filling structure is controlled by adjusting for the osmolarity of the filling fluid medium. The filling structures may be delivered over balloon deployment mechanisms in order to shape occlude the aneurysm and open a tubular lumen for flow of blood through the filling structure. | 08-09-2012 |
20120184982 | Methods and Systems for Treating Aneurysms - A system for treating an aneurysm comprises an elongate flexible shaft and a nosecone. An expandable member may be used to expand an expandable endoframe within a double-walled filling structure. The filling structure is adapted to be filled with a hardenable fluid filing medium so that an outer wall conforms to an inside surface of the aneurysm and an inner wall forms a substantially tubular lumen to provide a path for blood flow. In the expanded configuration the endoframe engages the inner wall of the filling structure. One or more tethers releasably couple the filling structure and/or endoframe with the shaft thereby constraining axial movement of the structures relative to each other. The nosecone is constructed to have a series of side ports and a through lumen such that the nosecone can be positioned with a guidewire and simultaneously receive a contrast media for performing angiography through the lumen. | 07-19-2012 |
20120165917 | STENT GRAFT - Some embodiments are directed to a stent graft comprising a first stent graft having a first and a second stent and a first and a second inner graft supported by the first stent, and an outer graft. The second inner graft can be spaced apart from the first inner graft so that a portion of the first stent is not covered by either the first inner graft or the second inner graft. A first and second portion of the outer graft can be attached to the first stent, the outer graft being unsupported by the stent between the first and second portions so as to form a fillable space between the outer graft, the first inner graft, and the second inner graft. Some embodiments further comprise a second stent graft deployable within the inside of the first stent graft to sealingly cover the uncovered portion of the first stent. | 06-28-2012 |
20120109279 | APPARATUS AND METHOD OF PLACEMENT OF A GRAFT OR GRAFT SYSTEM - A fenestrated graft deployment system, with a delivery catheter having a catheter body, An endoluminal prosthesis having a main graft body, the main graft body having a lumen therethrough and a first opening laterally through a wall of the main graft body. A first guidewire prepositioned within the delivery catheter extending through at least a portion of the catheter body into a main lumen of the endoluminal prosthesis and through the first opening in the wall of the prosthesis when the delivery catheter is in a predeployed configuration. A first fenestration alignment device is configured to extend through at least a portion of the delivery catheter and is configured to be axially moveable relative to the first guidewire. The first fenestration alignment device has an end portion having an outside perimeter configured such that when an end portion of the fenestration alignment device moves toward the first opening of said main graft body the outside perimeter of the first opening is smaller than the outside perimeter of the first fenestration alignment device and prevents it from passing through the first opening and causes the main graft body adjacent to the first opening to move with the end of the first fenestration alignment device to act as alignment tool to allow an operator to align the first opening in the side of the endoluminal prosthesis with an ostium of a target branch vessel into which said first opening is to extend and act as a guide and seal for a subsequently delivered branch graft endoluminal prosthesis. | 05-03-2012 |
20120046684 | Graft Systems Having Filling Structures Supported by Scaffolds and Methods for Their Use - Aneurysms are treated by filling at least one double-walled filling structure with a curable medium within the aneurysm. The filling structures may be delivered over balloon deployment mechanisms in order to shape and open tubular lumens therethrough. Scaffolds are placed into the tubular lumens in order to help maintain the shape, anchor the filling structures in place, and provide improved blood flow transition into and out of the tubular lumens. | 02-23-2012 |
20120029610 | GRAFT DEPLOYMENT SYSTEM - A method for deploying a bifurcated endoluminal prosthesis at the junction of a main vessel and first and second branch vessels, comprising providing a deployment system containing a prosthesis having a main body section and first and second proximally extending branch sections, introducing the deployment system into the first branch vessel at a first access site, advancing the deployment system distally through at least a portion of the first branch vessel and into the main vessel, releasing the second branch section of the prosthesis by proximally retracting an outer sheath of the deployment system, expanding the main body section of the prosthesis from a radially compressed state within the deployment system to a radially expanded state within the main vessel by removing a first peelable sheath from the main branch section, and expanding the second branch section within the second branch vessel by proximally retracting a second branch release wire. | 02-02-2012 |
20120016456 | Stent Graft Delivery System - A system for treating an aneurysm comprises an elongate flexible shaft and an expandable member. An expandable scaffold is disposed over the expandable member and may be expanded from a collapsed configuration to an expanded configuration. A double-walled filling structure is disposed over the scaffold and has an outer wall and an inner wall. The filling structure is adapted to be filled with a hardenable fluid filing medium so that the outer wall conforms to an inside surface of the aneurysm and the inner wall forms a substantially tubular lumen to provide a path for blood flow. In the expanded configuration the scaffold engages the inner wall of the filling structure. A tether is releasably coupled with the filling structure and the flexible shaft thereby constraining axial movement of the structures relative to each other. | 01-19-2012 |
20110224782 | SELF EXPANDING BIFURCATED ENDOVASCULAR PROSTHESIS - Disclosed is a bifurcated tubular endoluminal vascular prosthesis, useful in treating, for example, an abdominal aortic aneurysm. The prosthesis comprises a self expandable wire support structure surrounded at least in part by a flexible tubular membrane. A delivery catheter and methods are also disclosed. | 09-15-2011 |
20110224772 | BIFURCATED GRAFT DEPLOYMENT SYSTEMS AND METHODS - A method for deploying an endoluminal vascular prosthesis using a deployment catheter that has at least a main graft portion and a first branch graft portion. The deployment catheter preferably comprises an elongate, flexible catheter body having a proximal end and a distal end, and an outer sheath and an inner core that is axially moveable with respect to the outer sheath. The catheter preferably comprises a main graft restraint that has a main graft release mechanism comprising a main graft sheath and a suture threaded through a plurality of the openings in the main graft sheath. The catheter further comprises at least one branch graft restraint comprising at least one branch graft release mechanism. | 09-15-2011 |
20110218617 | ENDOLUMINAL VASCULAR PROSTHESIS - Some embodiments of an endoluminal prosthesis comprise a graft having a first end and a second end, a first stent positioned at a first end of the graft, the first stent comprising a plurality of proximal apices and a plurality of distal apices, a second stent positioned axially adjacent to the first stent comprising a plurality of proximal apices positioned at a first end of the second stent. In some embodiments, the first stent can be partially covered by the graft such that the proximal apices of the first stent are not covered by the graft. The distal apices of the first stent can be positioned approximately on a first or a second plane offset from the first plane. The second stent can be positioned relative to the first stent such that the plurality of proximal apices of the second stent are spaced apart from the plurality of distal apices of the first stent. Further, one or more of the proximal apices of the second stent can be positioned approximately on a third or a fourth plane. The distal apices of the first stent can be circumferentially offset from the proximal apices of the second stent. | 09-08-2011 |
20110054594 | FENESTRATED PROSTHESIS - Some embodiments of the present disclosure are directed to endoluminal prostheses having one or more reinforced fenestrations therein. The one or more reinforced fenestrations can have improved sealing capabilities with respect to branch grafts deployed within the fenestrations, improved tear resistance and expandability, and improved pull-out resistance for branch grafts. In some embodiments, the endoluminal prosthesis can have a main graft body defining a flow lumen therethrough, a first opening passing through a wall of the main graft body, and a first support member supported by the main graft body and overlapping an edge of the first opening, the first support member being configured to at least increase the tear resistance of the main graft body adjacent to the first opening. The support member can be stitched or otherwise attached to the main graft adjacent to the fenestration. | 03-03-2011 |
20110054587 | APPARATUS AND METHOD OF PLACEMENT OF A GRAFT OR GRAFT SYSTEM - Some embodiments of the present disclosure are directed to a method of deploying a graft in a patient's blood vessel having at least a first and a second branch blood vessel, comprising advancing a delivery catheter into a blood vessel, the delivery catheter supporting a fenestrated prosthesis therein, wherein the prosthesis comprises a main graft body, exposing at least one branch sheath, the branch sheath being positioned within the delivery catheter so as to project from a main lumen of the prosthesis through a first opening formed through a wall of the prosthesis, and advancing an angiographic catheter into the branch sheath and cannulating a first target branch vessel before expanding the main graft body of the prosthesis. | 03-03-2011 |
20110054586 | APPARATUS AND METHOD OF PLACEMENT OF A GRAFT OR GRAFT SYSTEM - Some embodiments relate to endoluminal prostheses having a first stent portion and a second stent portion, a main graft body comprising first, second, and third portions, the second portion having a cross-sectional size that is significantly larger than a cross-sectional size of the first or third portions, and also significantly larger than a cross-sectional size of the target vessel. In some embodiments, the first portion of the main graft body can be attached to the first stent portion and the third portion of the main graft body can be attached to the second stent portion. The prostheses can be configured such that the second portion of the main graft body is not directly attached to the first stent portion, the second stent portion, or any other internal support structure. In some embodiments, one or more openings can be formed in the second portion of the main graft body. | 03-03-2011 |
20110022153 | STENT GRAFT - Some embodiments are directed to a stent graft comprising a first stent graft having a first stent, a first inner graft supported by the first stent, a second inner graft supported by the first stent, and an outer graft. The second inner graft can be spaced apart from the first inner graft along the length of the first stent so that a portion of the first stent is not covered by either the first inner graft or the second inner graft. A first portion and a second portion of the outer graft can be attached to the first stent, the outer graft being unsupported by the stent between the first and second portions so as to form a fillable space between the outer graft, the first inner graft, and the second inner graft. Some embodiments further comprise a second stent graft deployable within the inside of the first stent graft to sealingly cover the uncovered portion of the first stent. | 01-27-2011 |
20110015718 | STENT GRAFT - Some embodiments are directed to a deployment system for deploying a stent graft within a passageway, comprising a delivery catheter having an outer sheath, a proximal end, and a distal end, a stent having a first end and a second end, a graft having a first end and a second end, and at least one connecting element extending from the second end of the stent to the first end of the graft so as to connect the stent to the graft. In some embodiments, the stent can be supported within the outer sheath at a first axial position in a collapsed state, and the graft can be supported within the outer sheath at a second axial position different than the first axial position in a collapsed state, such that the stent does not overlap or substantially overlap the graft in the collapsed state within the deployment system. | 01-20-2011 |
20100318181 | IMPLANTABLE VASCULAR GRAFT - Disclosed is a tubular endoluminal vascular prosthesis, useful in treating, for example, an abdominal aortic aneurysm. The prosthesis comprises a self-expandable wire support structure having a tubular main body support and first and second branch supports. The prosthesis can have a plurality of radially outwardly extending barbs. The branch supports may articulate with the main body to permit the branches to pivot laterally from the axis of the main body throughout a substantial range of motion. | 12-16-2010 |
20100318174 | IMPLANTABLE VASCULAR GRAFT - Disclosed is a tubular endoluminal vascular prosthesis, useful in treating, for example, an abdominal aortic aneurysm. The prosthesis comprises a self-expandable wire support structure having a tubular main body support and first and second branch supports. The prosthesis can have a plurality of radially outwardly extending barbs. The branch supports may articulate with the main body to permit the branches to pivot laterally from the axis of the main body throughout a substantial range of motion. | 12-16-2010 |
20100280588 | PERCUTANEOUS METHOD AND DEVICE TO TREAT DISSECTIONS - Some embodiments of the present disclosure are directed to methods and systems for percutaneously treating dissections in a patient's vasculature, such as, without limitation, the aorta. The method can include deploying a catheter containing a collapsed anchoring element, frame, and cover through a first vessel to an entry point of the dissection. In some embodiments, the anchoring element can be secured to the second branch vessel. The frame can be expanded in the first branch vessel. The cover can be unfolded over at least a portion of the entry point. The cover then reduces blood flow into the entry point. | 11-04-2010 |
20100261662 | UTILIZATION OF MURAL THROMBUS FOR LOCAL DRUG DELIVERY INTO VASCULAR TISSUE - The present disclosure is directed to methods and systems for stabilizing an extracellular matrix in a wall of a blood vessel. The method comprises delivering a therapeutic agent into mural thrombus, which covers the wall of the blood vessel. The agent is transported from the mural thrombus into the extracellular matrix of the vessel wall by diffusion. The agent then acts to reduce the enzymatic degradation of protein in the extracellular matrix. | 10-14-2010 |
20100179638 | SINGLE PUNCTURE BIFURCATION GRAFT DEPLOYMENT SYSTEM - The present invention relates to the endoluminal repair of abdominal aortic aneurysms at the aortic and iliac bifurcation. In particular, a deployment system and graft are disclosed for deploying the bifurcated graft within both iliac branches, as well as the aortic trunk, from a single vascular access. | 07-15-2010 |
20100004730 | CATHETER SYSTEM AND METHODS OF USING SAME - Some embodiments are directed to a catheter system comprising an introducer having a main body, an introducer sheath projecting from the main body, and a first seal supported within the introducer and a catheter having a main body, an outer sheath projecting from the main body, a second seal supported within the catheter, and an inner core configured to be advanced axially through the main body, the second seal, and the outer sheath. The introducer can be configured to be selectively engageable with the catheter so that the catheter can be selectively and removably linked with the introducer in the axial direction. The catheter system can also be configured such that, when the introducer and the catheter are linked, the catheter can be rotatable relative to the introducer. The introducer can be configured to radially restrain an endoluminal prosthesis. | 01-07-2010 |
20090216315 | METHOD OF PLACEMENT OF A GRAFT OR GRAFT SYSTEM - An endoluminal prosthesis system deployable in a region of a patient's vasculature having one or more branch vessels, having a first main graft body having at least a first and second opening therein and a second main graft body having at least a first and a second opening therein. The first openings can be smaller than the second openings. The second main graft body can be expandable substantially within the first main graft body such that the second openings of each graft body do not substantially cover the first openings of the other graft body. The resulting graft system can have two openings therein, each being defined by the first openings in each of the first and second main graft bodies. One or more branch grafts can be attached to cover the openings in the main graft bodies, and the main graft bodies can have one or more cutouts therein. | 08-27-2009 |
20090155337 | METHOD AND AGENT FOR IN-SITU STABILIZATION OF VASCULAR TISSUE - A method for stabilizing an extra cellular matrix layer in the vascular system of the body is disclosed herein. The method can comprise placing a vascular catheter adjacent to the extra cellular matrix layer, delivering a solution containing a bioflavonoid to the extra cellular matrix layer with the vascular catheter, and cross-linking protein in the extra cellular matrix layer. The bioflavonoid can be a catechin, particularly epigallocatechin gallate (EGCG). | 06-18-2009 |
20090105806 | STENT - A tubular prosthesis can be formed by rolling a sheet of material about a longitudinal axis, thereby forming a plurality of annular rings that can be arranged so as to be longitudinally adjacent one another, thus forming a tubular prosthesis. Each annular member can expand and contract independent of the other annular members. A graft material can extend between the plurality of annular members. | 04-23-2009 |