EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH Patent applications |
Patent application number | Title | Published |
20140343324 | SYNTHETIC MATRIX FOR CONTROLLED CELL INGROWTH AND TISSUE REGENERATION - Biomaterials containing a three-dimensional polymeric network formed from the reaction of a composition containing at least a first synthetic precursor molecule having n nucleophilic groups and a second precursor molecule having m electrophilic groups wherein the sum of n+m is at least five and wherein the sum of the weights of the first and second precursor molecules is in a range from about 8 to about 16% b weight of the composition, preferably from about 10 to about 15%, more preferably from about 12 to about 14.5% by weight of the composition. In one embodiment, the first and second precursor molecules are polyethylene glycols functionalized with nucleophilic and electrophilic groups, respectively. In a preferred embodiment, the nucleophilic groups are amino and/or thiol groups and the electrophilic groups are conjugated, unsaturated groups. The ratio of the equivalent weights of the electrophilic groups (second precursor molecule) and the nucleophilic groups (first precursor molecule) is in the range of between 0.7 and 1.1, more preferably between 0.8 and 1.0. The first and/or second precursor molecule may be covalently bound to one or more molecules selected from the group consisting of cell adhesion peptides, growth factors, and growth factor-like peptides. | 11-20-2014 |
20140133745 | OBJECT RECOGNITION DEVICE - A learning unit | 05-15-2014 |
20140072670 | METHOD FOR PRODUCING NON-BOVINE CHYMOSIN AND USE HEREOF - A method of recombinantly producing a non-bovine pre-prochymosin, prochymosin or chymosin derived from ruminant species including deer species, buffalo species, antelope species, giraffe species, ovine species and caprine species; | 03-13-2014 |
20130189663 | MEDICAL TRAINING SYSTEMS AND METHODS - Simulation systems and methods may enable virtual imaging. A data processing unit may receive data from a calibration unit indicating a position and/or orientation of a position and orientation sensor relative to a physical model. The data processing unit may also receive data from the position and orientation sensor indicating a position and/or orientation of the physical model. The data processing unit may generate a virtual image using the data from the position and orientation sensor and the data from the calibration unit. The data processing unit may render the virtual image to a display. | 07-25-2013 |
20130146758 | HIGH-DENSITY SAMPLE SUPPORT PLATE FOR AUTOMATED SAMPLE ALIQUOTING - A sample support plate ( | 06-13-2013 |
20120314017 | Transparent Autostereoscopic Image Display Apparatus and Method - An image display apparatus includes a display layer and an image separation layer. The image separation layer is adapted to separate a displayed image on the display layer into a first image for a left eye of an observer and into a second image for a right eye of an observer. This renders the image display apparatus autostereoscopic. In order to improve the appearance of the displayed image, the apparatus is adapted to activate the display layer and the image separation layer substantially only within a given two-dimensional silhouette and to remain substantially transparent outside of the silhouette. In other aspects, the apparatus may be adapted to dynamically adjust an observation angle between the first image and the second image by controlling the distance between the display layer and the image separation layer by an actuator. The apparatus may be mounted on a robotic unit. | 12-13-2012 |
20120130538 | Method to Control a Robot Device and Robot Device - A method to control a robot device that includes at least one manipulator which is moveable in an operating space, at least one actuator which actuates the manipulator, a sensor arrangement having at least one position sensor to determine the actual position of the manipulator and a controller which controls the actuator. The manipulator moves along an actual trajectory by means of an external force provided by an operator. The actuator provides compensation forces onto the manipulator influencing the torques or forces exchanged between operator and manipulator. The controller includes a conservative force field module having a conservative force field. The controller provides control signals for the actuator which provides the compensation force based on the control signals. The control signals are based on the conservative force field and on the actual position of the manipulator. | 05-24-2012 |
20110233472 | POROUS CERAMIC CATALYSTS AND METHODS FOR THEIR PRODUCTION AND USE - A method of producing a rigid catalytically active porous ceramic is disclosed. Catalyst particles comprising a catalytically active material or a precursor thereof are mixed with a chemical additive, a ceramic binder, a carrier liquid and, optionally, substantially inert carrier particles to obtain a slurry having a gel-or paste-like consistency. The slurry may be transported to a substrate, e.g., by printing, or to a reactor cavity by a suitable flow method. The slurry is then heated to substantially evaporate said carrier liquid to obtain a rigid, catalytically active porous ceramic in situ. A catalyst obtainable by such a method and the use of such a catalyst are also disclosed. | 09-29-2011 |
20110227247 | POLYMER ARTICLES, AND METHODS AND DIES FOR MAKING THE SAME - Provided are dies having a first section for orienting material being pressed through the die and a second section for shaping the oriented material into a desired form. In an embodiment, the surface area for shaping the oriented material into a desired form is limited. Also provided are polymer articles and processes for making the same. In an embodiment, the processes employ the dies. | 09-22-2011 |
20110178273 | METHOD FOR HIGH THROUGHPUT PEPTIDE/PROTEIN ASSAY GENERATION AND ASSAYS GENERATED THEREWITH - The invention relates to a method for the determination of an MRM or SRM assay for a protein of interest, a peptide of interest, or a group of proteins/peptides of interest or a whole proteome. It essentially includes the following steps: (1) a list of proteins of interest is selected and for each member at least one or a list of candidate proteotypic peptides is derived (2) this at least one peptide is synthesized/generated essentially without subsequent purification; (3) this at least one unpurified peptide is analyzed by selected reaction monitoring (SRM) preferably coupled to liquid chromatography (LC-SRM) or analogous techniques; (4) validation and/or optimisation of the corresponding assay of the at least one peptide with determination of the SRM coordinates for a peptide/protein of interest and/or of a regulator of interest is achieved. A protein sample of interest is enzymatically digested and can then be analyzed in SRM mode or time-constrained SRM mode, using elution times to trigger acquisition of the set of selected SRM traces, thus drastically increasing the throughput. The analysis allows to detect and quantify the set of peptides/proteins of interest. The method additionally relates to a tagging strategy to achieve absolute quantification of the peptides/proteins of interest at low-budget and high-throughput. | 07-21-2011 |
20110093066 | Degradable Biocompatible Block Copolymer - Disclosed is a biocompatible block copolymer containing the polycondensation product of a diol and an additional component selected from the group of the same diol, an α,ω-dihydroxy-polyester or an α,ω-dihydroxy-polyether. Also disclosed are a medical implant containing the block copolymer, the use of said block copolymer for the production of a medical implant, a diol and a method for the production thereof. The diol may be obtained by transesterification of α,ω-dihydroxy-[(oligo(3-(R)-hydroxybutyrate)-ethylene-oligo-(3-(R)-hydroxybutyrate)] with diglycolide. Transesterification is carried out, preferably, in the presence of a catalyst. | 04-21-2011 |
20110042310 | METHOD AND DEVICE FOR CHROMATOGRAPHIC PURIFICATION - A process for continuous or quasi-continuous purification of a multi-component mixture (F) by means of individual chromatographic columns through which the mixture is fed by means of at least one solvent(s). The multi-component mixture (F) at least comprises light impurities (A), an intermediate product (B) to be purified and heavy impurities (C), and the columns are grouped into at least four sections (α,β,γ,δ). After or within a switch time (t*) the last column from the first section (α) is moved to the first position of the second section (β), the last column of the second section (β) is moved to the first position of the third section (γ), the last column of the third section (γ) is moved to the first position of the fourth section (δ) and the last column of the fourth section (δ) is moved to become the first column of the first section (α). | 02-24-2011 |
20100309226 | METHOD AND SYSTEM FOR IMAGE-BASED INFORMATION RETRIEVAL - For retrieving information based on images, a first image is taken (S | 12-09-2010 |
20100276734 | ELECTROCHEMICAL BIOSENSOR ARRAYS AND SYSTEMS AND METHODS OF MAKING SAME - Electrochemical biosensor arrays and systems, as well as methods of making the electrochemical biosensor arrays and systems, are described herein. The electrochemical biosensor systems can be used with CMOS detection circuits that have a plurality of chemical detection and/or actuation channels or sites. The biosensor systems generally include a first inert conducting electrode disposed on a first portion of a CMOS detection circuit and a polymeric layer adjacent the first inert conducting electrode. The biosensor systems can also include a capture biomolecule bound to the polymeric layer. The biosensor system can also include the CMOS detection and/or actuation circuit having a plurality of channels. | 11-04-2010 |
20100062484 | Recombinant n-glycosylated proteins from procaryotic cells - The present invention relates to recombinant N-glycosylated proteins, comprising one or more introduced N-glycosylated optimized amino acid sequence(s), nucleic acids encoding these proteins as well as corresponding vectors and host cells. In addition, the present invention is directed to the use of said proteins, nucleic acids, vectors and host cells for preparing medicaments. Furthermore, the present invention provides methods for producing said proteins. | 03-11-2010 |
20100051916 | METHOD FOR FORMING AN ELECTRONIC DEVICE IN MULTI-LAYER STRUCTURE - A method for forming an organic or partly organic switching device, comprising: depositing layers of conducting, semiconducting and/or insulating layers by solution processing and direct printing; defining microgrooves in the multilayer structure by solid state embossing; and forming a switching device inside the microgroove. | 03-04-2010 |
20100035375 | MASKLESS NANOFABRICATION OF ELECTRONIC COMPONENTS - The present invention relates to systems, materials and methods for the formation of conducting, semiconducting, and dielectric layers, structures and devices from suspensions of nanoparticles. Drop-on-demand systems are used in some embodiments to fabricate various electronic structures including conductors, capacitors, FETs. Selective laser ablation is used in some embodiments to pattern more precisely the circuit elements and to form small channel devices. | 02-11-2010 |
20090315978 | METHOD AND SYSTEM FOR GENERATING A 3D REPRESENTATION OF A DYNAMICALLY CHANGING 3D SCENE - A method for generating a 3D representation of a dynamically changing 3D scene, which includes the steps of:
| 12-24-2009 |
20090295019 | Polymer gel-processing techniques and high modulus products - The present invention provides polymer gel-processing techniques and polymer articles of high modulus. | 12-03-2009 |
20090291224 | Porous Ceramic Thin Film - A sheet-like substrate ( | 11-26-2009 |
20090252965 | Surface functionalization and coating of flame-generated nanoparticles - A method for generating a chemically bonded organic functionality on the surface of particles or for condensing an organic compound onto the particle surface giving an organic coating is described. The method comprises a step of contacting a vapour containing an organic compound and a gaseous process stream containing flame-generated particles so as to react the organic compound with surface groups on the particles to give a chemically bonded organic functionality to the particle surface or so as to result in an organic coating. | 10-08-2009 |
20090248172 | POROUS MEMBRANE COMPRISING A BIOCOMPATIBLE BLOCK-COPOLYMER - The invention relates to a membrane comprising a biocompatible block copolymer and has a porous structure with regularly distributed pores. A method for preparing said membranes is also provided. | 10-01-2009 |
20090215588 | Device and Method for an Automatic Treadmill Therapy - A method to control the velocity of a treadmill according to the walking velocity of the person that is using the treadmill. A reaction force is measured, which occurs when a longitudinal repulsion force is created between the treadmill ( | 08-27-2009 |
20090186838 | Amphotericin Derivatives - The present invention provides new polyene macrolide derivatives which show very low toxicity while retaining high antifungal activity as compared with amphotericin B (AmB). These polyene macrolide derivatives comprise a polyene macrolide backbone having at least one free amino group, wherein the amino group is doubly alkylated with at least one hydrocarbon group carrying a total of at least two basic groups. | 07-23-2009 |
20090149783 | System And Method For A Cooperative Arm Therapy And Corresponding Rotation Module - A system for arm therapy of a user comprises a device for determining the position of the user, a first drive, an upper arm rotation module, an upper arm cuff, at least one hinge movably connecting the upper arm cuff and the first drive, a second drive, and a rotation drive provided on the upper arm rotation module itself. The upper arm cuff is connected to the arm of the user and has a substantially hollow-cylindrical shape when it is closed. The first drive and the second drive are adapted to place the upper arm rotation module in a defined spatial position, and the rotation drive is adapted to turn the upper arm cuff about its main axis relative to the outer part of the upper arm rotation module. | 06-11-2009 |
20090050567 | Method and device for chromatographic purification - A process for continuous or quasi-continuous purification of a multi-component mixture (F) by means of individual chromatographic columns through which the mixture is fed by means of at least one solvent (s), is proposed. The multi-component mixture (F) at least comprises light impurities (A), an intermediate product (B) to be purified and heavy impurities (C), and the columns are grouped into at least four sections (α, β, γ, δ), in which the first section (α) is provided with at least one inlet of solvent (s) and at least one outlet for purified intermediate product (B), such that it washes the purified intermediate product (B) out of the system, but keeps the heavy impurities (C) inside the section (α), the one inlet of solvent (β) and at least one outlet connected to an inlet of the fourth section (δ), such that it washes the intermediate product (B), which is contaminated with heavy impurities (C) into the fourth section (δ) through said outlet, but keeps the pure heavy impurities (C) inside the section (β), the third section (γ) is provided with at least one inlet of solvent (s) and an outlet for heavy impurities (C), such that it washes out the heavy impurities (C) through said outlet and cleans the chromatographic column(s), the fourth section (δ) is provided with at least one inlet to receive output of the outlet of the second section (β) as well as at least one inlet for feeding in the multi-component mixture (F) and at least one outlet for light impurities (A), such that it washes the light impurities (A) out of the system, but keeps the intermediate product (B) inside the section (δ), wherein after or within a switch time (t*) the last column from the first section (α) is moved to the first position of the second section (β), the last column of the second section (β) is moved to the first position of the third section (γ), the last column of the third section (γ) is moved to the first position of the fourth section (δ) and the last column of the fourth section (δ) is moved to become the first column of the first section (α). | 02-26-2009 |
20090029195 | THIN FILM AND COMPOSITE ELEMENT PRODUCED FROM THE SAME - A thin film consisting of at least two layers of a ceramic material, a ceramic and metallic material, or in the case of several layers a metallic material. All layers of the thin film have a maximum average particle size of approximately 500 nm and at least two layers consist of different material. In at least one of said layers, an essentially stable average particle size remains after a relaxation time, even in an increased temperature range. The mechanical stability is preferably reinforced by a supporting, essentially flat substrate. In the composite element, the thickness of the substrate is at least five times and in particular between ten and a hundred times the thickness of the thin film. The composite element can be successfully used in a miniaturised electrochemical device, in particular in a solid oxide fuel cell SOFC, a sensor or as a gas separation membrane. | 01-29-2009 |
20090011315 | Thin-Film Composite and a Glass Ceramic Substrate Used in a Miniaturized Electrochemical Device - A composite element comprising a thin film that consists of at least two layers of an oxide-ceramic and metallic material, or a metallic material and an essentially flat substrate that supports the thin film. Said substrate is composed of a ceramicizable glass, a glass ceramic, a hybrid form or an intermediate product. To produce the substrate, selected regions are dissolved out of the photostructurable glass substrate. The composite element can be successfully used in a miniaturised electrochemical device, in particular in a solid oxide fuel cell SOFC, a sensor or as a gas separation membrane. | 01-08-2009 |
20080287813 | Blood Pressure Monitoring Device and Methods for Making and for Using Such a Device - Disclosed are a system and a method for noninvasively and continuously monitoring blood pressure. Also disclosed is a method for making such a device. The system includes a semiconductor chip comprising a transducer array of individual pressure or force sensors and associated circuitry providing control signals to and/or processing signals from these sensors, all of the above integrated in the chip. Also disclosed is a specific sensor structure provided on said chip. The invention further encompasses a system for measuring and/or tracking the blood pressure waveform and for combining the latter with related blood values like the heartbeat, derived from the above or other measuring devices. | 11-20-2008 |